10 New Thesis Statement about Depression & Anxiety | How to Write One?

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Did you know according to the National Institute of Mental Health; it is estimated that approximately 8.4% of adults are patients of major depression in the US? Well, depression is a common illness globally that affects a lot of people. Yet, the reasons for this psychological sickness vary from person to person and numerous studies are being conducted to discover more about depression.

Therefore, college and university students are currently assigned to write research papers, dissertations, essays, and a thesis about depression. However, writing essays on such topics aims to increase the awareness of physical and mental well-being among youth and help them find solutions.

However, a lot of students find it pretty challenging to write a thesis statement about depression and seek someone to write my essay . No worries! In this article, you will learn about what is a good thesis statement about mental health and some effective methods and approaches to write a killer headline and compose an astonishing essay about depression.

5 Thesis Statement About Depression:

  • “The complexity of depression, which includes biological, psychological, and environmental components, emphasizes the need for individualized treatment plans that consider each person’s particular requirements.”
  • “Depression in the workplace not only affects an individual’s productivity but also carries economic implications, emphasizing the importance of fostering a mental health-friendly work environment.”
  • “Alternative, holistic approaches to mental health care have the potential to be more successful as the link between creative expressions, such as art therapy, and depression management becomes more commonly recognized.”
  • “It is critical to enhance geriatric mental health treatment and reduce the stigma associated with mental illness in older people since depression in senior populations is typically underdiagnosed and mistreated.”
  • “The link between early childhood adversity and the risk of developing depression later in life accentuates the importance of early intervention and support systems for children exposed to adverse experiences.”

5 Thesis Statements about Anxiety & Depression :

  • “Depression and anxiety Co-occurring disorders are a major concern in mental health, necessitating integrated treatment options that meet the unique challenges that co-occurring diseases provide.”
  • “The utilization of technology-driven therapies, such as smartphone apps and telehealth services, is a realistic approach of addressing persons suffering from anxiety and depression, while also increasing access to mental health care.”
  • “The examination of the gut-brain connection and its potential role in anxiety and depression showcases a burgeoning area of research that could lead to novel treatments emphasizing nutrition and gut health.”
  • “Adolescents who experience both anxiety and depression face a serious issue that calls for comprehensive school-based mental health programs and preventative measures to promote young people’s mental health.”
  • “Exploring the impact of sociocultural factors and the role of community support systems in the experience of anxiety and depression provides insights into the development of culturally sensitive mental health interventions.”

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Follow 7 Proven Methods to Compose Thesis Statement about Depression

A thesis is the overview of the concepts and ideas that you will write in your research paper or in the essay. Yet, a thesis statement about anxiety focuses more on the stress and depression topics for the paper you’re working on, which can be written by following the tips given below.

Nonetheless, you can compose an outline by covering the points mentioned below:

1. Pick a good study topic and perform a basic reading. Look for some intriguing statistics and try to come up with creative ways to approach your subject. Examine a few articles for deficiencies in understanding.

2. Make a list of your references and jot down when you come across a noteworthy quotation. You can cite them in your paper as references. Organize all of the information you’ve acquired in one location.

3. In one phrase, state the purpose of your essay. Consider what you want to happen when other people read your article.

4. Examine your notes and construct a list of all the key things you wish to emphasize. Make use of brainstorming strategies and jot down any ideas that come to mind.

5. Review and revise the arguments and write a thesis statement for a research paper or essay about depression.

6. Organize your essay by organizing the list of points. Arrange the points in a logical sequence. Analyze all elements to ensure that they are all relevant to your goal.

7. Reread all of your statements and arrange your outline in a standard manner, such as a bulleted list.

Final Words

So, what is an ideal way to write a thesis statement about depression for your research paper or essay? We hope you have a thorough idea of the essay you’re writing before picking a thesis statement about mental well-being. That will assist you in developing the greatest thesis for our essay.

But don’t get too worked up over your thesis statement for a research paper on mental disorders. Our professional subject experts have produced a list of thesis statements about mental health and depression themes for research paper writing, so you’ve got your job cut out for you. For your essay assignments or assignments, we will also offer appropriate thesis statements.

If you’re still confused about which statement to use, contact us right away. We have a staff of highly qualified and seasoned writers who can assist you with your essay or research work and guarantee that you receive the highest possible score.

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What Is a Good Thesis Statement About Depression?

Lonely girl with depression

Do you need to compose an informative or an argumentative essay on depression? One of the vital parts of your paper is a thesis statement on depression. Note there are various types of thesis statements, and what you use depends on the type of essay you are writing. A thesis summarizes the concept that you write on your research paper or the bottom line that you will write in your essay. It should elaborate more on the depression topics for the research paper you are working on. But at times, you might have a hard time writing your thesis statement.

Good Thesis Statement about Teenage Depression

Bipolar disorder thesis statements about depression, interesting thesis statements about depression, interesting thesis statement about diagnosis and treatment of depression, thesis statement about stress and depression, free thesis statements about depression and anxiety, get help with your depression research paper.

Here is a list of thesis statements to have an easier time writing your essay. They cover different topics, making it easy to select what excites you. Here we go!

Are you writing about teenagers and how they are always overthinking about their future, and they end up getting depressed? You need to write a good thesis statement for a depression research paper. That will help your depression argumentative essay stand out. Here are some thesis statement for depression to check out.

  • There is a link between depression and alcohol among teenagers and the various ways to control it.
  • Teenagers dealing with mood disorders eat and sleep more than usual, getting less interested in regular activities.
  • Mediation is an effective way to reach out to adolescents that show heightened symptoms of depression.
  • Self-blaming attributions are social cognitive mechanisms among adolescents.
  • Peer victimization causes high-stress levels among adolescents and has negative psychological consequences.

Choosing a good depression thesis statement on bipolar disorder can be hectic. Research on bipolar will require a good thesis statement for mental health. Choose a thesis statement about mental health awareness here.

  • People with Bipolar depression have more difficulties getting quality sleep.
  • Bipolar disorder influences every aspect of a person’s life and changes their quality of life.
  • Bipolar disorder causes depressive moods or lows of mental disorder.
  • Bipolar is a severe mental issue that can negatively impact your moods, self-esteem, and behavior.
  • Psychological evaluations play a significant role in diagnosing bipolar disorder.

When writing your essay, ensure that the thesis statement for mental health is fascinating. You will impress your professors if you get the right depression research paper outline as your thesis statement. Here is a depression thesis statement you can use.

  • The effects of human psychology are viewed in the form of depression.
  • Clinical psychology can help to bring outpatients who have depression.
  • Treating long-term depression in bipolar patients is possible.
  • Bipolar patients are drained to the roots of depression.
  • Well-established rehabilitation centers can help bring drug addicts from depression.

Are you thinking of writing a thesis on depression and how to treat it? If so, you need to have an excellent thesis statement about mental health that will impress your professor. Read this list to find a thesis you need for your research paper.

  • There are different ways to diagnose and treat depression from its early stage.
  • People who show signs of depression from an early stage and seek treatment are likely to recover instead of those who do not show early signs.
  • After you receive treatment for depression, putting the right measure in place is one of the best and effective ways to ensure that you do not get it again for the second time.
  • Anxiety can interfere with daily living, and it can get anyone from children to adults.
  • Besides medication, you need a lifestyle change and acceptance to treat depression.

Is your research about stress and how it can impact mental health? Getting a thesis statement for depression research paper that impresses your examiners can be challenging. Choose a thesis statement for your mental illness research paper below.

  • Although it is normal for various situations to cause stress, having constant stress can have detrimental effects.
  • To survive the modern industrial society, you need to have stress management strategies.
  • The challenges of understanding and adapting to the changing environment can lead to stress.
  • Lack of proper stress management will lead to inefficiency in everything people do.
  • Stress does not come unless there are underlying stressors in your life.

Our team of writers is well-conversant about a free thesis statement about anxiety you can use. The best anxiety thesis statement will help you get the best grades. Here is a list of statements that stands out:

  • Many factors can lead to early anxiety, but the leading cause of anxiety in adolescents is directly linked to families.
  • Anxiety is a severe mental disorder that can occur without any apparent triggers.
  • Long-term depression and anxiety can impact your mental health, but you can recover if you seek treatment.
  • Depression and anxiety are not interlinked, and it is essential to learn how to differentiate them on practical grounds.
  • Society has a role to play in helping people come out of depression and anxiety.

How do you write a research paper about depression and how it affects mental health? Before choosing a thesis statement on mental health, have a clear understanding of the essay that you are writing. That will help you get the best thesis to make our essay stand out.

But don’t keep stressing out about your thesis statement for mental illness research paper. We have your work cut out because our skilled writers have compiled a list of thesis statements about mental health and depression topics for research paper writing. We will also suggest correct thesis statements for your essay homework or assignment.

If you are still unsure of the statement to use, get in touch with us today. We have a team of skilled and experienced writers that can help you with your essay or research project and ensure that you get the best grades.

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7 Depression Research Paper Topic Ideas

In psychology classes, it's common for students to write a depression research paper. Researching depression may be beneficial if you have a personal interest in this topic and want to learn more, or if you're simply passionate about this mental health issue. However, since depression is a very complex subject, it offers many possible topics to focus on, which may leave you wondering where to begin.

If this is how you feel, here are a few research titles about depression to help inspire your topic choice. You can use these suggestions as actual research titles about depression, or you can use them to lead you to other more in-depth topics that you can look into further for your depression research paper.

What Is Depression?

Everyone experiences times when they feel a little bit blue or sad. This is a normal part of being human. Depression, however, is a medical condition that is quite different from everyday moodiness.

Your depression research paper may explore the basics, or it might delve deeper into the  definition of clinical depression  or the  difference between clinical depression and sadness .

What Research Says About the Psychology of Depression

Studies suggest that there are biological, psychological, and social aspects to depression, giving you many different areas to consider for your research title about depression.

Types of Depression

There are several different types of depression  that are dependent on how an individual's depression symptoms manifest themselves. Depression symptoms may vary in severity or in what is causing them. For instance, major depressive disorder (MDD) may have no identifiable cause, while postpartum depression is typically linked to pregnancy and childbirth.

Depressive symptoms may also be part of an illness called bipolar disorder. This includes fluctuations between depressive episodes and a state of extreme elation called mania. Bipolar disorder is a topic that offers many research opportunities, from its definition and its causes to associated risks, symptoms, and treatment.

Causes of Depression

The possible causes of depression are many and not yet well understood. However, it most likely results from an interplay of genetic vulnerability  and environmental factors. Your depression research paper could explore one or more of these causes and reference the latest research on the topic.

For instance, how does an imbalance in brain chemistry or poor nutrition relate to depression? Is there a relationship between the stressful, busier lives of today's society and the rise of depression? How can grief or a major medical condition lead to overwhelming sadness and depression?

Who Is at Risk for Depression?

This is a good research question about depression as certain risk factors may make a person more prone to developing this mental health condition, such as a family history of depression, adverse childhood experiences, stress , illness, and gender . This is not a complete list of all risk factors, however, it's a good place to start.

The growing rate of depression in children, teenagers, and young adults is an interesting subtopic you can focus on as well. Whether you dive into the reasons behind the increase in rates of depression or discuss the treatment options that are safe for young people, there is a lot of research available in this area and many unanswered questions to consider.

Depression Signs and Symptoms

The signs of depression are those outward manifestations of the illness that a doctor can observe when they examine a patient. For example, a lack of emotional responsiveness is a visible sign. On the other hand, symptoms are subjective things about the illness that only the patient can observe, such as feelings of guilt or sadness.

An illness such as depression is often invisible to the outside observer. That is why it is very important for patients to make an accurate accounting of all of their symptoms so their doctor can diagnose them properly. In your depression research paper, you may explore these "invisible" symptoms of depression in adults or explore how depression symptoms can be different in children .

How Is Depression Diagnosed?

This is another good depression research topic because, in some ways, the diagnosis of depression is more of an art than a science. Doctors must generally rely upon the patient's set of symptoms and what they can observe about them during their examination to make a diagnosis. 

While there are certain  laboratory tests that can be performed to rule out other medical illnesses as a cause of depression, there is not yet a definitive test for depression itself.

If you'd like to pursue this topic, you may want to start with the Diagnostic and Statistical Manual of Mental Disorders (DSM). The fifth edition, known as DSM-5, offers a very detailed explanation that guides doctors to a diagnosis. You can also compare the current model of diagnosing depression to historical methods of diagnosis—how have these updates improved the way depression is treated?

Treatment Options for Depression

The first choice for depression treatment is generally an antidepressant medication. Selective serotonin reuptake inhibitors (SSRIs) are the most popular choice because they can be quite effective and tend to have fewer side effects than other types of antidepressants.

Psychotherapy, or talk therapy, is another effective and common choice. It is especially efficacious when combined with antidepressant therapy. Certain other treatments, such as electroconvulsive therapy (ECT) or vagus nerve stimulation (VNS), are most commonly used for patients who do not respond to more common forms of treatment.

Focusing on one of these treatments is an option for your depression research paper. Comparing and contrasting several different types of treatment can also make a good research title about depression.

A Word From Verywell

The topic of depression really can take you down many different roads. When making your final decision on which to pursue in your depression research paper, it's often helpful to start by listing a few areas that pique your interest.

From there, consider doing a little preliminary research. You may come across something that grabs your attention like a new study, a controversial topic you didn't know about, or something that hits a personal note. This will help you narrow your focus, giving you your final research title about depression.

Remes O, Mendes JF, Templeton P. Biological, psychological, and social determinants of depression: A review of recent literature . Brain Sci . 2021;11(12):1633. doi:10.3390/brainsci11121633

National Institute of Mental Health. Depression .

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition . American Psychiatric Association.

National Institute of Mental Health. Mental health medications .

Ferri, F. F. (2019). Ferri's Clinical Advisor 2020 E-Book: 5 Books in 1 . Netherlands: Elsevier Health Sciences.

By Nancy Schimelpfening Nancy Schimelpfening, MS is the administrator for the non-profit depression support group Depression Sanctuary. Nancy has a lifetime of experience with depression, experiencing firsthand how devastating this illness can be.  

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An Exploratory Study of Students with Depression in Undergraduate Research Experiences

  • Katelyn M. Cooper
  • Logan E. Gin
  • M. Elizabeth Barnes
  • Sara E. Brownell

*Address correspondence to: Katelyn M. Cooper ( E-mail Address: [email protected] ).

Department of Biology, University of Central Florida, Orlando, FL, 32816

Search for more papers by this author

Biology Education Research Lab, Research for Inclusive STEM Education Center, School of Life Sciences, Arizona State University, Tempe, AZ 85281

Depression is a top mental health concern among undergraduates and has been shown to disproportionately affect individuals who are underserved and underrepresented in science. As we aim to create a more inclusive scientific community, we argue that we need to examine the relationship between depression and scientific research. While studies have identified aspects of research that affect graduate student depression, we know of no studies that have explored the relationship between depression and undergraduate research. In this study, we sought to understand how undergraduates’ symptoms of depression affect their research experiences and how research affects undergraduates’ feelings of depression. We interviewed 35 undergraduate researchers majoring in the life sciences from 12 research-intensive public universities across the United States who identify with having depression. Using inductive and deductive coding, we identified that students’ depression affected their motivation and productivity, creativity and risk-taking, engagement and concentration, and self-perception and socializing in undergraduate research experiences. We found that students’ social connections, experiencing failure in research, getting help, receiving feedback, and the demands of research affected students’ depression. Based on this work, we articulate an initial set of evidence-based recommendations for research mentors to consider in promoting an inclusive research experience for students with depression.

INTRODUCTION

Depression is described as a common and serious mood disorder that results in persistent feelings of sadness and hopelessness, as well as a loss of interest in activities that one once enjoyed ( American Psychiatric Association [APA], 2013 ). Additional symptoms of depression include weight changes, difficulty sleeping, loss of energy, difficulty thinking or concentrating, feelings of worthlessness or excessive guilt, and suicidality ( APA, 2013 ). While depression results from a complex interaction of psychological, social, and biological factors ( World Health Organization, 2018 ), studies have shown that increased stress caused by college can be a significant contributor to student depression ( Dyson and Renk, 2006 ).

Depression is one of the top undergraduate mental health concerns, and the rate of depression among undergraduates continues to rise ( Center for Collegiate Mental Health, 2017 ). While we cannot discern whether these increasing rates of depression are due to increased awareness or increased incidence, it is clear that is a serious problem on college campuses. The percent of U.S. college students who self-reported a diagnosis with depression was recently estimated to be about 25% ( American College Health Association, 2019 ). However, higher rates have been reported, with one study estimating that up to 84% of undergraduates experience some level of depression ( Garlow et al. , 2008 ). Depression rates are typically higher among university students compared with the general population, despite being a more socially privileged group ( Ibrahim et al. , 2013 ). Prior studies have found that depression is negatively correlated with overall undergraduate academic performance ( Hysenbegasi et al. , 2005 ; Deroma et al. , 2009 ; American College Health Association, 2019 ). Specifically, diagnosed depression is associated with half a letter grade decrease in students’ grade point average ( Hysenbegasi et al. , 2005 ), and 21.6% of undergraduates reported that depression negatively affected their academic performance within the last year ( American College Health Association, 2019 ). Provided with a list of academic factors that may be affected by depression, students reported that depression contributed to lower exam grades, lower course grades, and not completing or dropping a course.

Students in the natural sciences may be particularly at risk for depression, given that such majors are noted to be particularly stressful due to their competitive nature and course work that is often perceived to “weed students out”( Everson et al. , 1993 ; Strenta et al. , 1994 ; American College Health Association, 2019 ; Seymour and Hunter, 2019 ). Science course instruction has also been described to be boring, repetitive, difficult, and math-intensive; these factors can create an environment that can trigger depression ( Seymour and Hewitt, 1997 ; Osborne and Collins, 2001 ; Armbruster et al ., 2009 ; Ceci and Williams, 2010 ). What also distinguishes science degree programs from other degree programs is that, increasingly, undergraduate research experiences are being proposed as an essential element of a science degree ( American Association for the Advancement of Science, 2011 ; President’s Council of Advisors on Science and Technology, 2012 ; National Academies of Sciences, Engineering, and Medicine [NASEM], 2017 ). However, there is some evidence that undergraduate research experiences can add to the stress of college for some students ( Cooper et al. , 2019c ). Students can garner multiple benefits from undergraduate research, including enhanced abilities to think critically ( Ishiyama, 2002 ; Bauer and Bennett, 2003 ; Brownell et al. , 2015 ), improved student learning ( Rauckhorst et al. , 2001 ; Brownell et al. , 2015 ), and increased student persistence in undergraduate science degree programs ( Jones et al. , 2010 ; Hernandez et al. , 2018 ). Notably, undergraduate research experiences are increasingly becoming a prerequisite for entry into medical and graduate programs in science, particularly elite programs ( Cooper et al. , 2019d ). Although some research experiences are embedded into formal lab courses as course-based undergraduate research experiences (CUREs; Auchincloss et al. , 2014 ; Brownell and Kloser, 2015 ), the majority likely entail working with faculty in their research labs. These undergraduate research experiences in faculty labs are often added on top of a student’s normal course work, so they essentially become an extracurricular activity that they have to juggle with course work, working, and/or personal obligations ( Cooper et al. , 2019c ). While the majority of the literature surrounding undergraduate research highlights undergraduate research as a positive experience ( NASEM, 2017 ), studies have demonstrated that undergraduate research experiences can be academically and emotionally challenging for students ( Mabrouk and Peters, 2000 ; Seymour et al. , 2004 ; Cooper et al. , 2019c ; Limeri et al. , 2019 ). In fact, 50% of students sampled nationally from public R1 institutions consider leaving their undergraduate research experience prematurely, and about half of those students, or 25% of all students, ultimately leave their undergraduate research experience ( Cooper et al. , 2019c ). Notably, 33.8% of these individuals cited a negative lab environment and 33.3% cited negative relationships with their mentors as factors that influenced their decision about whether to leave ( Cooper et al. , 2019c ). Therefore, students’ depression may be exacerbated in challenging undergraduate research experiences, because studies have shown that depression is positively correlated with student stress ( Hish et al. , 2019 ).

While depression has not been explored in the context of undergraduate research experiences, depression has become a prominent concern surrounding graduate students conducting scientific research. A recent study that examined the “graduate student mental health crisis” ( Flaherty, 2018 ) found that work–life balance and graduate students’ relationships with their research advisors may be contributing to their depression ( Evans et al. , 2018 ). Specifically, this survey of 2279 PhD and master’s students from diverse fields of study, including the biological/physical sciences, showed that 39% of graduate students have experienced moderate to severe depression. Fifty-five percent of the graduate students with depression who were surveyed disagreed with the statement “I have good work life balance,” compared to only 21% of students with depression who agreed. Additionally, the study highlighted that more students with depression disagreed than agreed with the following statements: their advisors provided “real” mentorship, their advisors provided ample support, their advisors positively impacted their emotional or mental well-being, their advisors were assets to their careers, and they felt valued by their mentors. Another recent study identified that depression severity in biomedical doctoral students was significantly associated with graduate program climate, a perceived lack of employment opportunities, and the quality of students’ research training environment ( Nagy et al. , 2019 ). Environmental stress, academic stress, and family and monetary stress have also been shown to be predictive of depression severity in biomedical doctoral students ( Hish et al. , 2019 ). Further, one study found that self-esteem is negatively correlated and stress is positively correlated with graduate student depression; presumably research environments that challenge students’ self-esteem and induce stress are likely contributing to depressive symptoms among graduate students ( Kreger, 1995 ). While these studies have focused on graduate students, and there are certainly notable distinctions between graduate and undergraduate research, the research-related factors that affect graduate student depression, including work–life balance, relationships with mentors, research environment, stress, and self-esteem, may also be relevant to depression among undergraduates conducting research. Importantly, undergraduates in the United States have reported identical levels of depression as graduate students but are often less likely to seek mental health care services ( Wyatt and Oswalt, 2013 ), which is concerning if undergraduate research experiences exacerbate depression.

Based on the literature on the stressors of undergraduate research experiences and the literature identifying some potential causes of graduate student depression, we identified three aspects of undergraduate research that may exacerbate undergraduates’ depression. Mentoring: Mentors can be an integral part of a students’ research experience, bolstering their connections with others in the science community, scholarly productivity, and science identity, as well as providing many other benefits ( Thiry and Laursen, 2011 ; Prunuske et al. , 2013 ; Byars-Winston et al. , 2015 ; Aikens et al. , 2016 , 2017 ; Thompson et al. , 2016 ; Estrada et al. , 2018 ). However, recent literature has highlighted that poor mentoring can negatively affect undergraduate researchers ( Cooper et al. , 2019c ; Limeri et al. , 2019 ). Specifically, one study of 33 undergraduate researchers who had conducted research at 10 institutions identified seven major ways that they experienced negative mentoring, which included absenteeism, abuse of power, interpersonal mismatch, lack of career support, lack of psychosocial support, misaligned expectations, and unequal treatment ( Limeri et al. , 2019 ). We hypothesize negative mentoring experiences may be particularly harmful for students with depression, because support, particularly social support, has been shown to be important for helping individuals with depression cope with difficult circumstances ( Aneshensel and Stone, 1982 ; Grav et al. , 2012 ). Failure: Experiencing failure has been hypothesized to be an important aspect of undergraduate research experiences that may help students develop some the most distinguishing abilities of outstanding scientists, such as coping with failure, navigating challenges, and persevering ( Laursen et al. , 2010 ; Gin et al. , 2018 ; Henry et al. , 2019 ). However, experiencing failure and the stress and fatigue that often accompany it may be particularly tough for students with depression ( Aldwin and Greenberger, 1987 ; Mongrain and Blackburn, 2005 ). Lab environment: Fairness, inclusion/exclusion, and social support within one’s organizational environment have been shown to be key factors that cause people to either want to remain in the work place and be productive or to want to leave ( Barak et al. , 2006 ; Cooper et al. , 2019c ). We hypothesize that dealing with exclusion or a lack of social support may exacerbate depression for some students; patients with clinical depression react to social exclusion with more pronounced negative emotions than do individuals without clinical depression ( Jobst et al. , 2015 ). While there are likely other aspects of undergraduate research that affect student depression, we hypothesize that these factors have the potential to exacerbate negative research experiences for students with depression.

Depression has been shown to disproportionately affect many populations that are underrepresented or underserved within the scientific community, including females ( American College Health Association, 2018 ; Evans et al. , 2018 ), first-generation college students ( Jenkins et al. , 2013 ), individuals from low socioeconomic backgrounds ( Eisenberg et al. , 2007 ), members of the LGBTQ+ community ( Eisenberg et al. , 2007 ; Evans et al. , 2018 ), and people with disabilities ( Turner and Noh, 1988 ). Therefore, as the science community strives to be more diverse and inclusive ( Intemann, 2009 ), it is important that we understand more about the relationship between depression and scientific research, because negative experiences with depression in scientific research may be contributing to the underrepresentation of these groups. Specifically, more information is needed about how the research process and environment of research experiences may affect depression.

Given the high rate of depression among undergraduates, the links between depression and graduate research, the potentially challenging environment of undergraduate research, and how depression could disproportionately impact students from underserved communities, it is imperative to begin to explore the relationship between scientific research and depression among undergraduates to create research experiences that could maximize student success. In this exploratory interview study, we aimed to 1) describe how undergraduates’ symptoms of depression affect their research experiences, 2) understand how undergraduate research affects students’ feelings of depression, and 3) identify recommendations based on the literature and undergraduates’ reported experiences to promote a positive research experience for students with depression.

This study was done with an approved Arizona State University Institutional Review Board protocol #7247.

In Fall 2018, we surveyed undergraduate researchers majoring in the life sciences across 25 research-intensive (R1) public institutions across the United States (specific details about the recruitment of the students who completed the survey can be found in Cooper et al. (2019c) ). The survey asked students for their opinions about their undergraduate research experiences and their demographic information and whether they would be interested in participating in a follow-up interview related to their research experiences. For the purpose of this study, we exclusively interviewed students about their undergraduate research experiences in faculty member labs; we did not consider students’ experiences in CUREs. Of the 768 undergraduate researchers who completed the survey, 65% ( n = 496) indicated that they would be interested in participating in a follow-up interview. In Spring 2019, we emailed the 496 students, explaining that we were interested in interviewing students with depression about their experiences in undergraduate research. Our specific prompt was: “If you identify as having depression, we would be interested in hearing about your experience in undergraduate research in a 30–60 minute online interview.” We did not define depression in our email recruitment because we conducted think-aloud interviews with four undergraduates who all correctly interpreted what we meant by depression ( APA, 2013 ). We had 35 students agree to participate in the interview study. The interview participants represented 12 of the 25 R1 public institutions that were represented in the initial survey.

Student Interviews

We developed an interview script to explore our research questions. Specifically, we were interested in how students’ symptoms of depression affect their research experiences, how undergraduate research negatively affects student depression, and how undergraduate research positively affects student depression.

We recognized that mental health, and specifically depression, can be a sensitive topic to discuss with undergraduates, and therefore we tried to minimize any discomfort that the interviewees might experience during the interview. Specifically, we conducted think-aloud interviews with three graduate students who self-identified with having depression at the time of the interview. We asked them to note whether any interview questions made them uncomfortable. We also sought their feedback on questions given their experiences as persons with depression who had once engaged in undergraduate research. We revised the interview protocol after each think-aloud interview. Next, we conducted four additional think-aloud interviews with undergraduates conducting basic science or biology education research who identified with having depression to establish cognitive validity of the questions and to elicit additional feedback about any questions that might make someone uncomfortable. The questions were revised after each think-aloud interview until no question was unclear or misinterpreted by the students and we were confident that the questions minimized students’ potential discomfort ( Trenor et al. , 2011 ). A copy of the final interview script can be found in the Supplemental Material.

All interviews were individually conducted by one of two researchers (K.M.C. and L.E.G.) who conducted the think-aloud interviews together to ensure that their interviewing practices were as similar as possible. The interviews were approximately an hour long, and students received a $15 gift card for their participation.

Personal, Research, and Depression Demographics

All student demographics and information about students’ research experiences were collected using the survey distributed to students in Fall 2018. We collected personal demographics, including the participants’ gender, race/ethnicity, college generation status, transfer status, financial stability, year in college, major, and age. We also collected information about the students’ research experiences, including the length of their first research experiences, the average number of hours they spend in research per week, how they were compensated for research, who their primary mentors were, and the focus areas of their research.

In the United States, mental healthcare is disproportionately unavailable to Black and Latinx individuals, as well as those who come from low socioeconomic backgrounds ( Kataoka et al. , 2002 ; Howell and McFeeters, 2008 ; Santiago et al. , 2013 ). Therefore, to minimize a biased sample, we invited anyone who identified with having depression to participate in our study; we did not require students to be diagnosed with depression or to be treated for depression in order to participate. However, we did collect information about whether students had been formally diagnosed with depression and whether they had been treated for depression. After the interview, all participants were sent a link to a short survey that asked them if they had ever been diagnosed with depression and how, if at all, they had ever been treated for depression. A copy of these survey questions can be found in the Supplemental Material. The combined demographic information of the participants is in Table 1 . The demographics for each individual student can be found in the Supplemental Material.

Student-level demographics, research demographics, and depression demographics of the 35 interview participants

Student-level demographicsInterview participants = 35 (%)Research demographicsInterview participants = 35 (%)Depression demographicsInterview participants = 35 (%)
 Female27 (77%) Less than 6 months7 (20%) Yes21 (60%)
 Male7 (23%) 6 months6 (17%) No10 (29%)
 Declined to state1 (3%) 1 year11 (31%) Declined to state4 (11%)
 1.5 years4 (11%)
 Asian9 (26%) 2 years2 (6%) Medication15 (43%)
 Black1 (3%) 3 years3 (9%) Counseling17 (49%)
 Latinx5 (14%) 3.5 years1 (3%) Other2 (6%)
 Middle Eastern1 (3%) Declined to state1 (3%) No treatment15 (43%)
 Mixed race1 (3%)  Declined to state2 (6%)
 White17 (49%) 1–5 hours6 (17%)
 Declined to state1 (3%) 6–10 hours16 (46%)
 11–15 hours7 (20%)
 First generation10 (29%) 16 + hours5 (14%)
 Continuing generation24 (69%) Declined to state1 (3%)
 Declined to state1 (3%)
 Money13 (37%)
 Transfer5 (14%) Course credit24 (69%)
 Nontransfer29 (83%) Volunteer7 (20%)
 Declined to state1 (3%) Declined to state2 (6%)
 No6 (17%) PI9 (26%)
 Yes, but only sometimes12 (34%) Postdoc3 (9%)
 Yes16 (46%) Graduate student14 (40%)
 Declined to state1 (3%) Staff member 7 (20%)
 Undergraduate student1 (3%)
 First year1 (3%) Declined to state1 (3%)
 Second year5 (14%)
 Third year6 (17%) Cell/molecular biology4 (11%)
 Fourth year or greater22 (63%) Ecology/evolution9 (26%)
 Declined to state1 (3%) Genetics5 (14%)
 Immunology4 (11%)
 Biology32 (91%) Neuroscience3 (9%)
 Biochemistry2 (6%) Physiology/health3 (9%)
 Declined to state1 (3%) Other 6 (17%)
 Declined to state1 (3%)
 18–195 (14%)
 20–2117 (49%)
 22–2311 (31%)
 24 or older1 (3%)
 Declined to state1 (3%)

a Students reported the time they had spent in research 6 months before being interviewed and only reported on the length of time of their first research experiences.

b Students were invited to report multiple ways in which they were treated for their depression; other treatments included lifestyle changes and meditation.

c Students were invited to report multiple means of compensation for their research if they had been compensated for their time in different ways.

d Students were asked whether they felt financially stable, particularly during the undergraduate research experience.

e Students reported who they work/worked with most closely during their research experiences.

f Staff members included lab coordinators or lab managers.

g Other focus areas of research included sociology, linguistics, psychology, and public health.

Interview Analysis

The initial interview analysis aimed to explore each idea that a participant expressed ( Charmaz, 2006 ) and to identify reoccurring ideas throughout the interviews. First, three authors (K.M.C., L.E.G., and S.E.B.) individually reviewed a different set of 10 interviews and took detailed analytic notes ( Birks and Mills, 2015 ). Afterward, the authors compared their notes and identified reoccurring themes throughout the interviews using open coding methods ( Saldaña, 2015 ).

Once an initial set of themes was established, two researchers (K.M.C. and L.E.G.) individually reviewed the same set of 15 randomly selected interviews to validate the themes identified in the initial analysis and to screen for any additional themes that the initial analysis may have missed. Each researcher took detailed analytic notes throughout the review of an interview, which they discussed after reviewing each interview. The researchers compared what quotes from each interview they categorized into each theme. Using constant comparison methods, they assigned quotes to each theme and constantly compared the quotes to ensure that each quote fit within the description of the theme ( Glesne and Peshkin, 1992 ). In cases in which quotes were too different from other quotes, a new theme was created. This approach allowed for multiple revisions of the themes and allowed the authors to define a final set of codes; the researchers created a final codebook with refined definitions of emergent themes (the final coding rubric can be found in the Supplemental Material). Once the final codebook was established, the researchers (K.M.C. and L.E.G.) individually coded seven additional interviews (20% of all interviews) using the coding rubric. The researchers compared their codes, and their Cohen’s κ interrater score for these seven interviews was at an acceptable level (κ  =  0.88; Landis and Koch, 1977 ). One researcher (L.E.G.) coded the remaining 28 out of 35 interviews. The researchers determined that data saturation had been reached with the current sample and no further recruitment was needed ( Guest et al. , 2006 ). We report on themes that were mentioned by at least 20% of students in the interview study. In the Supplemental Material, we provide the final coding rubric with the number of participants whose interview reflected each theme ( Hannah and Lautsch, 2011 ). Reporting the number of individuals who reported themes within qualitative data can lead to inaccurate conclusions about the generalizability of the results to a broader population. These qualitative data are meant to characterize a landscape of experiences that students with depression have in undergraduate research rather than to make claims about the prevalence of these experiences ( Glesne and Peshkin, 1992 ). Because inferences about the importance of these themes cannot be drawn from these counts, they are not included in the results of the paper ( Maxwell, 2010 ). Further, the limited number of interviewees made it not possible to examine whether there were trends based on students’ demographics or characteristics of their research experiences (e.g., their specific area of study). Quotes were lightly edited for clarity by inserting clarification brackets and using ellipses to indicate excluded text. Pseudonyms were given to all students to protect their privacy.

The Effect of Depressive Symptoms on Undergraduate Research

We asked students to describe the symptoms associated with their depression. Students described experiencing anxiety that is associated with their depression; this could be anxiety that precedes their depression or anxiety that results from a depressive episode or a period of time when an individual has depression symptoms. Further, students described difficulty getting out of bed or leaving the house, feeling tired, a lack of motivation, being overly self-critical, feeling apathetic, and having difficulty concentrating. We were particularly interested in how students’ symptoms of depression affected their experiences in undergraduate research. During the think-aloud interviews that were conducted before the interview study, graduate and undergraduate students consistently described that their depression affected their motivation in research, their creativity in research, and their productivity in research. Therefore, we explicitly asked undergraduate researchers how, if at all, their depression affected these three factors. We also asked students to describe any additional ways in which their depression affected their research experiences. Undergraduate researchers commonly described five additional ways in which their depression affected their research; for a detailed description of each way students’ research was affected and for example quotes, see Table 2 . Students described that their depression negatively affected their productivity in the lab. Commonly, students described that their productivity was directly affected by a lack of motivation or because they felt less creative, which hindered the research process. Additionally, students highlighted that they were sometimes less productive because their depression sometimes caused them to struggle to engage intellectually with their research or caused them to have difficulty remembering or concentrating; students described that they could do mundane or routine tasks when they felt depressed, but that they had difficulty with more complex and intellectually demanding tasks. However, students sometimes described that even mundane tasks could be difficult when they were required to remember specific steps; for example, some students struggled recalling a protocol from memory when their depression was particularly severe. Additionally, students noted that their depression made them more self-conscious, which sometimes held them back from sharing research ideas with their mentors or from taking risks such as applying to competitive programs. In addition to being self-conscious, students highlighted that their depression caused them to be overly self-critical, and some described experiencing imposter phenomenon ( Clance and Imes, 1978 ) or feeling like they were not talented enough to be in research and were accepted into a lab by a fluke or through luck. Finally, students described that depression often made them feel less social, and they struggled to socially engage with other members of the lab when they were feeling down.

Ways in which students report that depression affected their undergraduate research experience with example student quotes

DescriptionExample quote 1Example quote 2
Motivation and productivity
Lack of motivation in researchStudents describe that their depression can cause them to feel unmotivated to do research.Crystal: “[Depression] can make it hard to motivate myself to keep doing [research] because when I get into [depression] it doesn’t matter. [All my organisms] are going to die and everything’s going to go horribly sideways and why do I even bother? And then that can descend into a state of just sadness or apathy or a combination of the two.”Naomi: “I don’t feel as motivated to do the research because I just don’t feel like doing anything. [Depression] definitely does not help with the motivation.”
Less productiveStudents describe that depression can cause them to be less productive, less efficient, or to move slower than usual.Marta: “I think at times when [my depression is] really, really bad, I’ll just find myself just sitting at my desk looking busy but not actually doing anything. (…) And I think that obviously affects productivity because I’m not really doing anything.”Julie: “I think I literally moved and thought slower. (…) I think that if I could redo all of that time while not depressed, I would have gotten so much more done. I feel like so much of this stalling I had on various projects was because of [my depression].”
Creativity and risk-taking
Lack of creativity in researchStudents describe that depression can cause them to be less creative in their research.Michelle: “In that depressive episode, I probably won’t be even using my brain in that, sort of, [creative] sense. My mind will probably be just so limited and blank and I won’t even want to think creatively.”Amy: “I think [depression] definitely has super negatively impacted my research creativity. I just feel like I’m not as creative with my problem solving skills when I am depressed as when I am not depressed.”
Held back from taking risks or contributing thoughts and ideasStudents describe that their depression can hold them back from sharing an idea with their lab mates or from taking risks like applying for competitive positions or trying something in research that might not work.Marta: “[Depression affects my research] because I’m so scared to take a risk. That has really put a very short cap on what I’ve been able to do. And maybe I would’ve been able to get internships at institutions like my peers. But instead, because I was so limited by my depression, it kept me from doing that.”Christian: “That’s where I think [depression] definitely negatively affects what I have accomplished just because I feel personally that I could have achieved more if I wasn’t held down, I guess, by depression. So, I feel like I would’ve been able to put myself out there more and take more risks, reaching out to others to take opportunities when I was in lab.”
Engagement and concentration
Struggle to intellectually engageStudents describe that they struggle to do research activities that require intellectual engagement when they are feeling depressed.Freddy: “I find mechanical things like actually running an experiment in the lab, I can pretty much do regardless of how I’m feeling. But things that require a ton of mental energy, like analyzing data, doing statistics, or actually writing, was [ ] a lot more difficult if I was feeling depressed.”Rose: “When you’re working on a research project you’re like ‘I wonder what this does? Or why is that the way it is?,’ and then you’ll read more articles and talk to a few people. And when I’m depressed, I don’t care. I’m like this is just another thing I have to do.”
Difficulty concentrating or rememberingStudents describe that, because of their depression, they can have difficulty concentrating or remembering when they are conducting research.Julie: “My memory absolutely goes to hell, especially my short-term memory. My attention span nosedives. Later, I will look back on work and have no idea how any of that made sense to me.”Adrianna: “Yeah. [Sometimes when I’m depressed] it’s like, ‘Oh, I forgot a step,’ or ‘Oh, I mislabeled the tube.’ It’s like, okay, I got to slow down even more and pay more attention. But it’s really hard to get myself to focus.”
Self-perception and socializing
Overly self-criticalStudents describe that depression causes them to have low self-esteem or to be overly self-critical.Heather: “I guess [my depression can cause me to] beat myself up about different things. Especially when the experiment didn’t really work. I guess blaming myself to the point where it was unhealthy about different things. If I had an experiment and it didn’t work, even if I was working with someone else, then I’d put all the blame on myself. I guess [your depression] worsens it because you just feel worse about yourself mentally.”Taylor: “I feel like I’m sort of not good enough, right? And I’ve sort of fooled [my research advisor] for letting me into their lab, and that I should just stop. I guess that’s really how [my depression] would relate directly to research.”
Less socialStudents describe that their depression can cause them to not want to interact with others in the lab or to be less social in general.Adrianna: “There are days I’m emotionally flat and obviously those I just don’t engage in conversation as much and [my lab mates] are probably like, ‘Oh, she’s just under the weather.’ I don’t know. It just affects my ability to want to sit down and talk to somebody.”Michelle: “When I’m depressed I won’t talk as much, so [my lab mates and I] won’t have a conversation.”

The Effect of Undergraduate Research Experiences on Student Depression

We also wanted to explore how research impacted students’ feelings of depression. Undergraduates described how research both positively and negatively affected their depression. In the following sections, we present aspects of undergraduate research and examine how each positively and/or negatively affected students’ depression using embedded student quotes to highlight the relationships between related ideas.

Lab Environment: Relationships with Others in the Lab.

Some aspects of the lab environment, which we define as students’ physical, social, or psychological research space, could be particularly beneficial for students with depression.

Specifically, undergraduate researchers perceived that comfortable and positive social interactions with others in the lab helped their depression. Students acknowledged how beneficial their relationships with graduate students and postdocs could be.

Marta: “I think always checking in on undergrads is important. It’s really easy [for us] to go a whole day without talking to anybody in the lab. But our grad students are like ‘Hey, what’s up? How’s school? What’s going on?’ (…) What helps me the most is having that strong support system. Sometimes just talking makes you feel better, but also having people that believe in you can really help you get out of that negative spiral. I think that can really help with depression.”

Kelley: “I know that anytime I need to talk to [my postdoc mentors] about something they’re always there for me. Over time we’ve developed a relationship where I know that outside of work and outside of the lab if I did want to talk to them about something I could talk to them. Even just talking to someone about hobbies and having that relationship alone is really helpful [for depression].”

In addition to highlighting the importance of developing relationships with graduate students or postdocs in the lab, students described that forming relationships with other undergraduates in the lab also helped their depression. Particularly, students described that other undergraduate researchers often validated their feelings about research, which in turn helped them realize that what they are thinking or feeling is normal, which tended to alleviate their negative thoughts. Interestingly, other undergraduates experiencing the same issues could sometimes help buffer them from perceiving that a mentor did not like them or that they were uniquely bad at research. In this article, we use the term “mentor” to refer to anyone who students referred to in the interviews as being their mentors or managing their research experiences; this includes graduate students, postdoctoral scholars, lab managers, and primary investigators (PIs).

Abby: “One of my best friends is in the lab with me.  A lot of that friendship just comes from complaining about our stress with the lab and our annoyance with people in the lab. Like when we both agree like, ‘Yeah, the grad students were really off today, it wasn’t us,’ that helps. ‘It wasn’t me, it wasn’t my fault that we were having a rough day in lab; it was the grad students.’ Just being able to realize, ‘Hey, this isn’t all caused by us,’ you know? (…) We understand the stresses in the lab. We understand the details of what each other are doing in the lab, so when something doesn’t work out, we understand that it took them like eight hours to do that and it didn’t work. We provide empathy on a different level.”

Meleana: “It’s great to have solidarity in being confused about something, and it’s just that is a form of validation for me too. When we leave a lab meeting and I look at [another undergrad] I’m like, ‘Did you understand anything that they were just saying?’ And they’re like, ‘Oh, no.’ (…) It’s just really validating to hear from the other undergrads that we all seem to be struggling with the same things.”

Developing positive relationships with faculty mentors or PIs also helped alleviate some students’ depressive feelings, particularly when PIs shared their own struggles with students. This also seemed to normalize students’ concerns about their own experiences.

Alexandra: “[Talking with my PI] is helpful because he would talk about his struggles, and what he faced. A lot of it was very similar to my struggles.  For example, he would say, ‘Oh, yeah, I failed this exam that I studied so hard for. I failed the GRE and I paid so much money to prepare for it.’ It just makes [my depression] better, like okay, this is normal for students to go through this. It’s not an out of this world thing where if you fail, you’re a failure and you can’t move on from it.”

Students’ relationships with others in the lab did not always positively impact their depression. Students described instances when the negative moods of the graduate students and PIs would often set the tone of the lab, which in turn worsened the mood of the undergraduate researchers.

Abby: “Sometimes [the grad students] are not in a good mood. The entire vibe of the lab is just off, and if you make a joke and it hits somebody wrong, they get all mad. It really depends on the grad students and the leadership and the mood that they’re in.”

Interviewer: “How does it affect your depression when the grad students are in a bad mood?”

Abby: “It definitely makes me feel worse. It feels like, again, that I really shouldn’t go ask them for help because they’re just not in the mood to help out. It makes me have more pressure on myself, and I have deadlines I need to meet, but I have a question for them, but they’re in a bad mood so I can’t ask. That’s another day wasted for me and it just puts more stress, which just adds to the depression.”

Additionally, some students described even more concerning behavior from research mentors, which negatively affected their depression.

Julie: “I had a primary investigator who is notorious in the department for screaming at people, being emotionally abusive, unreasonable, et cetera. (…) [He was] kind of harassing people, demeaning them, lying to them, et cetera, et cetera. (…) Being yelled at and constantly demeaned and harassed at all hours of the day and night, that was probably pretty bad for me.”

While the relationships between undergraduates and graduate, postdoc, and faculty mentors seemed to either alleviate or worsen students’ depressive symptoms, depending on the quality of the relationship, students in this study exclusively described their relationships with other undergraduates as positive for their depression. However, students did note that undergraduate research puts some of the best and brightest undergraduates in the same environment, which can result in students comparing themselves with their peers. Students described that this comparison would often lead them to feel badly about themselves, even though they would describe their personal relationship with a person to be good.

Meleana: “In just the research field in general, just feeling like I don’t really measure up to the people around me [can affect my depression]. A lot of the times it’s the beginning of a little spiral, mental spiral. There are some past undergrads that are talked about as they’re on this pedestal of being the ideal undergrads and that they were just so smart and contributed so much to the lab. I can never stop myself from wondering like, ‘Oh, I wonder if I’m having a contribution to the lab that’s similar or if I’m just another one of the undergrads that does the bare minimum and passes through and is just there.’”

Natasha: “But, on the other hand, [having another undergrad in the lab] also reminded me constantly that some people are invested in this and meant to do this and it’s not me. And that some people know a lot more than I do and will go further in this than I will.”

While students primarily expressed that their relationships with others in the lab affected their depression, some students explained that they struggled most with depression when the lab was empty; they described that they did not like being alone in the lab, because a lack of stimulation allowed their minds to be filled with negative thoughts.

Mia: “Those late nights definitely didn’t help [my depression]. I am alone, in the entire building.  I’m left alone to think about my thoughts more, so not distracted by talking to people or interacting with people. I think more about how I’m feeling and the lack of progress I’m making, and the hopelessness I’m feeling. That kind of dragged things on, and I guess deepened my depression.”

Freddy: “Often times when I go to my office in the evening, that is when I would [ sic ] be prone to be more depressed. It’s being alone. I think about myself or mistakes or trying to correct mistakes or whatever’s going on in my life at the time. I become very introspective. I think I’m way too self-evaluating, way too self-deprecating and it’s when I’m alone when those things are really, really triggered. When I’m talking with somebody else, I forget about those things.”

In sum, students with depression highlighted that a lab environment full of positive and encouraging individuals was helpful for their depression, whereas isolating or competitive environments and negative interactions with others often resulted in more depressive feelings.

Doing Science: Experiencing Failure in Research, Getting Help, Receiving Feedback, Time Demands, and Important Contributions.

In addition to the lab environment, students also described that the process of doing science could affect their depression. Specifically, students explained that a large contributor to their depression was experiencing failure in research.

Interviewer: “Considering your experience in undergraduate research, what tends to trigger your feelings of depression?”

Heather: “Probably just not getting things right. Having to do an experiment over and over again. You don’t get the results you want. (…) The work is pretty meticulous and it’s frustrating when I do all this work, I do a whole experiment, and then I don’t get any results that I can use. That can be really frustrating. It adds to the stress. (…) It’s hard because you did all this other stuff before so you can plan for the research, and then something happens and all the stuff you did was worthless basically.”

Julie: “I felt very negatively about myself [when a project failed] and pretty panicked whenever something didn’t work because I felt like it was a direct reflection on my effort and/or intelligence, and then it was a big glaring personal failure.”

Students explained that their depression related to failing in research was exacerbated if they felt as though they could not seek help from their research mentors. Perceived insufficient mentor guidance has been shown to be a factor influencing student intention to leave undergraduate research ( Cooper et al. , 2019c ). Sometimes students talked about their research mentors being unavailable or unapproachable.

Michelle: “It just feels like [the graduate students] are not approachable. I feel like I can’t approach them to ask for their understanding in a certain situation. It makes [my depression] worse because I feel like I’m stuck, and that I’m being limited, and like there’s nothing I can do. So then I kind of feel like it’s my fault that I can’t do anything.”

Other times, students described that they did not seek help in fear that they would be negatively evaluated in research, which is a fear of being judged by others ( Watson and Friend, 1969 ; Weeks et al. , 2005 ; Cooper et al. , 2018 ). That is, students fear that their mentor would think negatively about them or judge them if they were to ask questions that their mentor thought they should know the answer to.

Meleana: “I would say [my depression] tends to come out more in being more reserved in asking questions because I think that comes more like a fear-based thing where I’m like, ‘Oh, I don’t feel like I’m good enough and so I don’t want to ask these questions because then my mentors will, I don’t know, think that I’m dumb or something.’”

Conversely, students described that mentors who were willing to help them alleviated their depressive feelings.

Crystal: “Yeah [my grad student] is always like, ‘Hey, I can check in on things in the lab because you’re allowed to ask me for that, you’re not totally alone in this,’ because he knows that I tend to take on all this responsibility and I don’t always know how to ask for help. He’s like, ‘You know, this is my lab too and I am here to help you as well,’ and just reminds me that I’m not shouldering this burden by myself.”

Ashlyn: “The graduate student who I work with is very kind and has a lot of patience and he really understands a lot of things and provides simple explanations. He does remind me about things and he will keep on me about certain tasks that I need to do in an understanding way, and it’s just because he’s patient and he listens.”

In addition to experiencing failure in science, students described that making mistakes when doing science also negatively affected their depression.

Abby: “I guess not making mistakes on experiments [is important in avoiding my depression]. Not necessarily that your experiment didn’t turn out to produce the data that you wanted, but just adding the wrong enzyme or messing something up like that. It’s like, ‘Oh, man,’ you know? You can get really down on yourself about that because it can be embarrassing.”

Commonly, students described that the potential for making mistakes increased their stress and anxiety regarding research; however, they explained that how other people responded to a potential mistake was what ultimately affected their depression.

Briana: “Sometimes if I made a mistake in correctly identifying an eye color [of a fly], [my PI] would just ridicule me in front of the other students. He corrected me but his method of correcting was very discouraging because it was a ridicule. It made the others laugh and I didn’t like that.”

Julie: “[My PI] explicitly [asked] if I had the dedication for science. A lot of times he said I had terrible judgment. A lot of times he said I couldn’t be trusted. Once I went to a conference with him, and, unfortunately, in front of another professor, he called me a klutz several times and there was another comment about how I never learn from my mistakes.”

When students did do things correctly, they described how important it could be for them to receive praise from their mentors. They explained that hearing praise and validation can be particularly helpful for students with depression, because their thoughts are often very negative and/or because they have low self-esteem.

Crystal: “[Something that helps my depression is] I have text messages from [my graduate student mentor] thanking me [and another undergraduate researcher] for all of the work that we’ve put in, that he would not be able to be as on track to finish as he is if he didn’t have our help.”

Interviewer: “Why is hearing praise from your mentor helpful?”

Crystal: “Because a lot of my depression focuses on everybody secretly hates you, nobody likes you, you’re going to die alone. So having that validation [from my graduate mentor] is important, because it flies in the face of what my depression tells me.”

Brian: “It reminds you that you exist outside of this negative world that you’ve created for yourself, and people don’t see you how you see yourself sometimes.”

Students also highlighted how research could be overwhelming, which negatively affected their depression. Particularly, students described that research demanded a lot of their time and that their mentors did not always seem to be aware that they were juggling school and other commitments in addition to their research. This stress exacerbated their depression.

Rose: “I feel like sometimes [my grad mentors] are not very understanding because grad students don’t take as many classes as [undergrads] do. I think sometimes they don’t understand when I say I can’t come in at all this week because I have finals and they’re like, ‘Why though?’”

Abby: “I just think being more understanding of student life would be great. We have classes as well as the lab, and classes are the priority. They forget what it’s like to be a student. You feel like they don’t understand and they could never understand when you say like, ‘I have three exams this week,’ and they’re like, ‘I don’t care. You need to finish this.’”

Conversely, some students reported that their research labs were very understanding of students’ schedules. Interestingly, these students talked most about how helpful it was to be able to take a mental health day and not do research on days when they felt down or depressed.

Marta: “My lab tech is very open, so she’ll tell us, ‘I can’t come in today. I have to take a mental health day.’ So she’s a really big advocate for that. And I think I won’t personally tell her that I’m taking a mental health day, but I’ll say, ‘I can’t come in today, but I’ll come in Friday and do those extra hours.’ And she’s like, ‘OK great, I’ll see you then.’  And it makes me feel good, because it helps me take care of myself first and then I can take care of everything else I need to do, which is amazing.”

Meleana: “Knowing that [my mentors] would be flexible if I told them that I’m crazy busy and can’t come into work nearly as much this week [helps my depression]. There is flexibility in allowing me to then care for myself.”

Interviewer: “Why is the flexibility helpful given the depression?”

Meleana: “Because sometimes for me things just take a little bit longer when I’m feeling down. I’m just less efficient to be honest, and so it’s helpful if I feel like I can only go into work for 10 hours in a week. It declutters my brain a little bit to not have to worry about all the things I have to do in work in addition the things that I need to do for school or clubs, or family or whatever.”

Despite the demanding nature of research, a subset of students highlighted that their research and research lab provided a sense of stability or familiarity that distracted them from their depression.

Freddy: “I’ll [do research] to run away from those [depressive] feelings or whatever. (…) I find sadly, I hate to admit it, but I do kind of run to [my lab]. I throw myself into work to distract myself from the feelings of depression and sadness.”

Rose: “When you’re sad or when you’re stressed you want to go to things you’re familiar with. So because lab has always been in my life, it’s this thing where it’s going to be there for me I guess. It’s like a good book that you always go back to and it’s familiar and it makes you feel good. So that’s how lab is. It’s not like the greatest thing in the world but it’s something that I’m used to, which is what I feel like a lot of people need when they’re sad and life is not going well.”

Many students also explained that research positively affects their depression because they perceive their research contribution to be important.

Ashlyn: “I feel like I’m dedicating myself to something that’s worthy and something that I believe in. It’s really important because it contextualizes those times when I am feeling depressed. It’s like, no, I do have these better things that I’m working on. Even when I don’t like myself and I don’t like who I am, which is again, depression brain, I can at least say, ‘Well, I have all these other people relying on me in research and in this area and that’s super important.’”

Jessica: “I mean, it just felt like the work that I was doing had meaning and when I feel like what I’m doing is actually going to contribute to the world, that usually really helps with [depression] because it’s like not every day you can feel like you’re doing something impactful.”

In sum, students highlighted that experiencing failure in research and making mistakes negatively contributed to depression, especially when help was unavailable or research mentors had a negative reaction. Additionally, students acknowledged that the research could be time-consuming, but that research mentors who were flexible helped assuage depressive feelings that were associated with feeling overwhelmed. Finally, research helped some students’ depression, because it felt familiar, provided a distraction from depression, and reminded students that they were contributing to a greater cause.

We believe that creating more inclusive research environments for students with depression is an important step toward broadening participation in science, not only to ensure that we are not discouraging students with depression from persisting in science, but also because depression has been shown to disproportionately affect underserved and underrepresented groups in science ( Turner and Noh, 1988 ; Eisenberg et al. , 2007 ; Jenkins et al. , 2013 ; American College Health Association, 2018 ). We initially hypothesized that three features of undergraduate research—research mentors, the lab environment, and failure—may have the potential to exacerbate student depression. We found this to be true; students highlighted that their relationships with their mentors as well as the overall lab environment could negatively affect their depression, but could also positively affect their research experiences. Students also noted that they struggled with failure, which is likely true of most students, but is known to be particularly difficult for students with depression ( Elliott et al. , 1997 ). We expand upon our findings by integrating literature on depression with the information that students provided in the interviews about how research mentors can best support students. We provide a set of evidence-based recommendations focused on mentoring, the lab environment, and failure for research mentors wanting to create more inclusive research environments for students with depression. Notably, only the first recommendation is specific to students with depression; the others reflect recommendations that have previously been described as “best practices” for research mentors ( NASEM, 2017 , 2019 ; Sorkness et al. , 2017 ) and likely would benefit most students. However, we examine how these recommendations may be particularly important for students with depression. As we hypothesized, these recommendations directly address three aspects of research: mentors, lab environment, and failure. A caveat of these recommendations is that more research needs to be done to explore the experiences of students with depression and how these practices actually impact students with depression, but our national sample of undergraduate researchers with depression can provide an initial starting point for a discussion about how to improve research experiences for these students.

Recommendations to Make Undergraduate Research Experiences More Inclusive for Students with Depression

Recognize student depression as a valid illness..

Allow students with depression to take time off of research by simply saying that they are sick and provide appropriate time for students to recover from depressive episodes. Also, make an effort to destigmatize mental health issues.

Undergraduate researchers described both psychological and physical symptoms that manifested as a result of their depression and highlighted how such symptoms prevented them from performing to their full potential in undergraduate research. For example, students described how their depression would cause them to feel unmotivated, which would often negatively affect their research productivity. In cases in which students were motivated enough to come in and do their research, they described having difficulty concentrating or engaging in the work. Further, when doing research, students felt less creative and less willing to take risks, which may alter the quality of their work. Students also sometimes struggled to socialize in the lab. They described feeling less social and feeling overly self-critical. In sum, students described that, when they experienced a depressive episode, they were not able to perform to the best of their ability, and it sometimes took a toll on them to try to act like nothing was wrong, when they were internally struggling with depression. We recommend that research mentors treat depression like any other physical illness; allowing students the chance to recover when they are experiencing a depressive episode can be extremely important to students and can allow them to maximize their productivity upon returning to research ( Judd et al. , 2000 ). Students explained that if they are not able to take the time to focus on recovering during a depressive episode, then they typically continue to struggle with depression, which negatively affects their research. This sentiment is echoed by researchers in psychiatry who have found that patients who do not fully recover from a depressive episode are more likely to relapse and to experience chronic depression ( Judd et al. , 2000 ). Students described not doing tasks or not showing up to research because of their depression but struggling with how to share that information with their research mentors. Often, students would not say anything, which caused them anxiety because they were worried about what others in the lab would say to them when they returned. Admittedly, many students understood why this behavior would cause their research mentors to be angry or frustrated, but they weighed the consequences of their research mentors’ displeasure against the consequences of revealing their depression and decided it was not worth admitting to being depressed. This aligns with literature that suggests that when individuals have concealable stigmatized identities, or identities that can be hidden and that carry negative stereotypes, such as depression, they will often keep them concealed to avoid negative judgment or criticism ( Link and Phelan, 2001 ; Quinn and Earnshaw, 2011 ; Jones and King, 2014 ; Cooper and Brownell, 2016 ; Cooper et al. , 2019b ; Cooper et al ., unpublished data ). Therefore, it is important for research mentors to be explicit with students that 1) they recognize mental illness as a valid sickness and 2) that students with mental illness can simply explain that they are sick if they need to take time off. This may be useful to overtly state on a research website or in a research syllabus, contract, or agreement if mentors use such documents when mentoring undergraduates in their lab. Further, research mentors can purposefully work to destigmatize mental health issues by explicitly stating that struggling with mental health issues, such as depression and anxiety, is common. While we do not recommend that mentors ask students directly about depression, because this can force students to share when they are not comfortable sharing, we do recommend providing opportunities for students to reveal their depression ( Chaudoir and Fisher, 2010 ). Mentors can regularly check in with students about how they’re doing, and talk openly about the importance of mental health, which may increase the chance that students may feel comfortable revealing their depression ( Chaudoir and Quinn, 2010 ; Cooper et al ., unpublished data ).

Foster a Positive Lab Environment.

Encourage positivity in the research lab, promote working in shared spaces to enhance social support among lab members, and alleviate competition among undergraduates.

Students in this study highlighted that the “leadership” of the lab, meaning graduate students, postdocs, lab managers, and PIs, were often responsible for establishing the tone of the lab; that is, if they were in a bad mood it would trickle down and negatively affect the moods of the undergraduates. Explicitly reminding lab leadership that their moods can both positively and negatively affect undergraduates may be important in establishing a positive lab environment. Further, students highlighted how they were most likely to experience negative thoughts when they were alone in the lab. Therefore, it may be helpful to encourage all lab members to work in a shared space to enhance social interactions among students and to maximize the likelihood that undergraduates have access to help when needed. A review of 51 studies in psychiatry supported our undergraduate researchers’ perceptions that social relationships positively impacted their depression; the study found that perceived emotional support (e.g., someone available to listen or give advice), perceived instrumental support (e.g., someone available to help with tasks), and large diverse social networks (e.g., being socially connected to a large number of people) were significantly protective against depression ( Santini et al. , 2015 ). Additionally, despite forming positive relationships with other undergraduates in the lab, many undergraduate researchers admitted to constantly comparing themselves with other undergraduates, which led them to feel inferior, negatively affecting their depression. Some students talked about mentors favoring current undergraduates or talking positively about past undergraduates, which further exacerbated their feelings of inferiority. A recent study of students in undergraduate research experiences highlighted that inequitable distribution of praise to undergraduates can create negative perceptions of lab environments for students (Cooper et al. , 2019). Further, the psychology literature has demonstrated that when people feel insecure in their social environments, it can cause them to focus on a hierarchical view of themselves and others, which can foster feelings of inferiority and increase their vulnerability to depression ( Gilbert et al. , 2009 ). Thus, we recommend that mentors be conscious of their behaviors so that they do not unintentionally promote competition among undergraduates or express favoritism toward current or past undergraduates. Praise is likely best used without comparison with others and not done in a public way, although more research on the impact of praise on undergraduate researchers needs to be done. While significant research has been done on mentoring and mentoring relationships in the context of undergraduate research ( Byars-Winston et al. , 2015 ; Aikens et al. , 2017 ; Estrada et al. , 2018 ; Limeri et al. , 2019 ; NASEM, 2019 ), much less has been done on the influence of the lab environment broadly and how people in nonmentoring roles can influence one another. Yet, this study indicates the potential influence of many different members of the lab, not only their mentors, on students with depression.

Develop More Personal Relationships with Undergraduate Researchers and Provide Sufficient Guidance.

Make an effort to establish more personal relationships with undergraduates and ensure that they perceive that they have access to sufficient help and guidance with regard to their research.

When we asked students explicitly how research mentors could help create more inclusive environments for undergraduate researchers with depression, students overwhelmingly said that building mentor–student relationships would be extremely helpful. Students suggested that mentors could get to know students on a more personal level by asking about their career interests or interests outside of academia. Students also remarked that establishing a more personal relationship could help build the trust needed in order for undergraduates to confide in their research mentors about their depression, which they perceived would strengthen their relationships further because they could be honest about when they were not feeling well or their mentors might even “check in” with them in times where they were acting differently than normal. This aligns with studies showing that undergraduates are most likely to reveal a stigmatized identity, such as depression, when they form a close relationship with someone ( Chaudoir and Quinn, 2010 ). Many were intimidated to ask for research-related help from their mentors and expressed that they wished they had established a better relationship so that they would feel more comfortable. Therefore, we recommend that research mentors try to establish relationships with their undergraduates and explicitly invite them to ask questions or seek help when needed. These recommendations are supported by national recommendations for mentoring ( NASEM, 2019 ) and by literature that demonstrates that both social support (listening and talking with students) and instrumental support (providing students with help) have been shown to be protective against depression ( Santini et al. , 2015 ).

Treat Undergraduates with Respect and Remember to Praise Them.

Avoid providing harsh criticism and remember to praise undergraduates. Students with depression often have low self-esteem and are especially self-critical. Therefore, praise can help calibrate their overly negative self-perceptions.

Students in this study described that receiving criticism from others, especially harsh criticism, was particularly difficult for them given their depression. Multiple studies have demonstrated that people with depression can have an abnormal or maladaptive response to negative feedback; scientists hypothesize that perceived failure on a particular task can trigger failure-related thoughts that interfere with subsequent performance ( Eshel and Roiser, 2010 ). Thus, it is important for research mentors to remember to make sure to avoid unnecessarily harsh criticisms that make students feel like they have failed (more about failure is described in the next recommendation). Further, students with depression often have low self-esteem or low “personal judgment of the worthiness that is expressed in the attitudes the individual holds towards oneself” ( Heatherton et al. , 2003 , p. 220; Sowislo and Orth, 2013 ). Specifically, a meta-analysis of longitudinal studies found that low self-esteem is predictive of depression ( Sowislo and Orth, 2013 ), and depression has also been shown to be highly related to self-criticism ( Luyten et al. , 2007 ). Indeed, nearly all of the students in our study described thinking that they are “not good enough,” “worthless,” or “inadequate,” which is consistent with literature showing that people with depression are self-critical ( Blatt et al. , 1982 ; Gilbert et al. , 2006 ) and can be less optimistic of their performance on future tasks and rate their overall performance on tasks less favorably than their peers without depression ( Cane and Gotlib, 1985 ). When we asked students what aspects of undergraduate research helped their depression, students described that praise from their mentors was especially impactful, because they thought so poorly of themselves and they needed to hear something positive from someone else in order to believe it could be true. Praise has been highlighted as an important aspect of mentoring in research for many years ( Ashford, 1996 ; Gelso and Lent, 2000 ; Brown et al. , 2009 ) and may be particularly important for students with depression. In fact, praise has been shown to enhance individuals’ motivation and subsequent productivity ( Hancock, 2002 ; Henderlong and Lepper, 2002 ), factors highlighted by students as negatively affecting their depression. However, something to keep in mind is that a student with depression and a student without depression may process praise differently. For a student with depression, a small comment that praises the student’s work may not be sufficient for the student to process that comment as praise. People with depression are hyposensitive to reward or have reward-processing deficits ( Eshel and Roiser, 2010 ); therefore, praise may affect students without depression more positively than it would affect students with depression. Research mentors should be mindful that students with depression often have a negative view of themselves, and while students report that praise is extremely important, they may have trouble processing such positive feedback.

Normalize Failure and Be Explicit about the Importance of Research Contributions.

Explicitly remind students that experiencing failure is expected in research. Also explain to students how their individual work relates to the overall project so that they can understand how their contributions are important. It can also be helpful to explain to students why the research project as a whole is important in the context of the greater scientific community.

Experiencing failure has been thought to be a potentially important aspect of undergraduate research, because it may provide students with the potential to develop integral scientific skills such as the ability to navigate challenges and persevere ( Laursen et al. , 2010 ; Gin et al. , 2018 ; Henry et al. , 2019 ). However, in the interviews, students described that when their science experiments failed, it was particularly tough for their depression. Students’ negative reaction to experiencing failure in research is unsurprising, given recent literature that has predicted that students may be inadequately prepared to approach failure in science ( Henry et al. , 2019 ). However, the literature suggests that students with depression may find experiencing failure in research to be especially difficult ( Elliott et al. , 1997 ; Mongrain and Blackburn, 2005 ; Jones et al. , 2009 ). One potential hypothesis is that students with depression may be more likely to have fixed mindsets or more likely to believe that their intelligence and capacity for specific abilities are unchangeable traits ( Schleider and Weisz, 2018 ); students with a fixed mindset have been hypothesized to have particularly negative responses to experiencing failure in research, because they are prone to quitting easily in the face of challenges and becoming defensive when criticized ( Forsythe and Johnson, 2017 ; Dweck, 2008 ). A study of life sciences undergraduates enrolled in CUREs identified three strategies of students who adopted adaptive coping mechanisms, or mechanisms that help an individual maintain well-being and/or move beyond the stressor when faced with failure in undergraduate research: 1) problem solving or engaging in strategic planning and decision making, 2) support seeking or finding comfort and help with research, and 3) cognitive restructuring or reframing a problem from negative to positive and engaging in self encouragement ( Gin et al. , 2018 ). We recommend that, when undergraduates experience failure in science, their mentors be proactive in helping them problem solve, providing help and support, and encouraging them. Students also explained that mentors sharing their own struggles as undergraduate and graduate students was helpful, because it normalized failure. Sharing personal failures in research has been recommended as an important way to provide students with psychosocial support during research ( NASEM, 2019 ). We also suggest that research mentors take time to explain to students why their tasks in the lab, no matter how small, contribute to the greater research project ( Cooper et al. , 2019a ). Additionally, it is important to make sure that students can explain how the research project as a whole is contributing to the scientific community ( Gin et al. , 2018 ). Students highlighted that contributing to something important was really helpful for their depression, which is unsurprising, given that studies have shown that meaning in life or people’s comprehension of their life experiences along with a sense of overarching purpose one is working toward has been shown to be inversely related to depression ( Steger, 2013 ).

Limitations and Future Directions

This work was a qualitative interview study intended to document a previously unstudied phenomenon: depression in the context of undergraduate research experiences. We chose to conduct semistructured interviews rather than a survey because of the need for initial exploration of this area, given the paucity of prior research. A strength of this study is the sampling approach. We recruited a national sample of 35 undergraduates engaged in undergraduate research at 12 different public R1 institutions. Despite our representative sample from R1 institutions, these findings may not be generalizable to students at other types of institutions; lab environments, mentoring structures, and interactions between faculty and undergraduate researchers may be different at other institution types (e.g., private R1 institutions, R2 institutions, master’s-granting institutions, primarily undergraduate institutions, and community colleges), so we caution against making generalizations about this work to all undergraduate research experiences. Future work could assess whether students with depression at other types of institutions have similar experiences to students at research-intensive institutions. Additionally, we intentionally did not explore the experiences of students with specific identities owing to our sample size and the small number of students in any particular group (e.g., students of a particular race, students with a graduate mentor as the primary mentor). We intend to conduct future quantitative studies to further explore how students’ identities and aspects of their research affect their experiences with depression in undergraduate research.

The students who participated in the study volunteered to be interviewed about their depression; therefore, it is possible that depression is a more salient part of these students’ identities and/or that they are more comfortable talking about their depression than the average population of students with depression. It is also important to acknowledge the personal nature of the topic and that some students may not have fully shared their experiences ( Krumpal, 2013 ), particularly those experiences that may be emotional or traumatizing ( Kahn and Garrison, 2009 ). Additionally, our sample was skewed toward females (77%). While females do make up approximately 60% of students in biology programs on average ( Eddy et al. , 2014 ), they are also more likely to report experiencing depression ( American College Health Association, 2018 ; Evans et al. , 2018 ). However, this could be because women have higher rates of depression or because males are less likely to report having depression; clinical bias, or practitioners’ subconscious tendencies to overlook male distress, may underestimate depression rates in men ( Smith et al. , 2018 ). Further, females are also more likely to volunteer to participate in studies ( Porter and Whitcomb, 2005 ); therefore, many interview studies have disproportionately more females in the data set (e.g., Cooper et al. , 2017 ). If we had been able to interview more male students, we might have identified different findings. Additionally, we limited our sample to life sciences students engaged in undergraduate research at public R1 institutions. It is possible that students in other majors may have different challenges and opportunities for students with depression, as well as different disciplinary stigmas associated with mental health.

In this exploratory interview study, we identified a variety of ways in which depression in undergraduates negatively affected their undergraduate research experiences. Specifically, we found that depression interfered with students’ motivation and productivity, creativity and risk-taking, engagement and concentration, and self-perception and socializing. We also identified that research can negatively affect depression in undergraduates. Experiencing failure in research can exacerbate student depression, especially when students do not have access to adequate guidance. Additionally, being alone or having negative interactions with others in the lab worsened students’ depression. However, we also found that undergraduate research can positively affect students’ depression. Research can provide a familiar space where students can feel as though they are contributing to something meaningful. Additionally, students reported that having access to adequate guidance and a social support network within the research lab also positively affected their depression. We hope that this work can spark conversations about how to make undergraduate research experiences more inclusive of students with depression and that it can stimulate additional research that more broadly explores the experiences of undergraduate researchers with depression.

Important note

If you or a student experience symptoms of depression and want help, there are resources available to you. Many campuses provide counseling centers equipped to provide students, staff, and faculty with treatment for depression, as well as university-dedicated crisis hotlines. Additionally, there are free 24/7 services such as Crisis Text Line, which allows you to text a trained live crisis counselor (Text “CONNECT” to 741741; Text Depression Hotline , 2019 ), and phone hotlines such as the National Suicide Prevention Lifeline at 1-800-273-8255 (TALK). You can also learn more about depression and where to find help near you through the Anxiety and Depression Association of American website: https://adaa.org ( Anxiety and Depression Association of America, 2019 ) and the Depression and Biopolar Support Alliance: http://dbsalliance.org ( Depression and Biopolar Support Alliance, 2019 ).

ACKNOWLEDGMENTS

We are extremely grateful to the undergraduate researchers who shared their thoughts and experiences about depression with us. We acknowledge the ASU LEAP Scholars for helping us create the original survey and Rachel Scott for her helpful feedback on earlier drafts of this article. L.E.G. was supported by a National Science Foundation (NSF) Graduate Fellowship (DGE-1311230) and K.M.C. was partially supported by a Howard Hughes Medical Institute (HHMI) Inclusive Excellence grant (no. 11046) and an NSF grant (no. 1644236). Any opinions, findings, conclusions, or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the NSF or HHMI.

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thesis statement in depression

Submitted: 4 November 2019 Revised: 24 February 2020 Accepted: 6 March 2020

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How To Write A Strong Essay On Depression?

Jared Houdi

Table of Contents

thesis statement in depression

Looking for useful information that will help you write a powerful essay on depression? You’ve come to the right place, then!

Depression is a worldwide spread disease that negatively affects how people feel, the way they think, and how they act. It is also the leading cause of disability. There are estimates that more than 300 million people are affected by depression globally, and this condition is also one of the most common mental disorders in the USA.

No wonder depression essay is a typical assignment for high school and college students. The goal of writing about this mental condition is to increase awareness among young people about mental health and help them find solutions to this problem.

In this guide, you will find all the necessary information for writing the best essays on this topic.

Depression essay: what’s the deal?

At some point in our lives, we all may experience symptoms like sadness, loss of interest, lack of pleasure from performing daily activities, etc.

For most people, these symptoms are a completely normal response to unpleasant or stressful events that they experience, for example, romantic relationships failures or financial issues.

Negative feelings are usually painful and overwhelming, but as time goes by, they become less intense and disappear.

But if these feelings persist, they may affect people’s life substantially and result in depression.

In recent decades, clinical depression has reached epidemic proportions and is widespread in the suburbs inner cities, farms, refugee camps, boardrooms, and classrooms, and women are more likely to be depressed than man.

Recent research reveals that the United States is the most depressed country in the world.

When writing an essay about this mental illness, you need to examine different aspects. For example, you may write a postpartum depression essay or explore how this mental condition affects the brain, personality, and physical health.

The choice of topics is endless, but you should follow standard writing requirements when working on your projects. Let’s discuss some important steps of writing an essay about mental disorders in detail.

Depression research paper outline: a brief how-to

Many students skip this stage in the writing process and as a result, may waste a lot of time when doing research and actually writing.

Creating a working outline for your project is an essential step that will help you stay focused and increase your overall productivity. Never skip this crucial step if you want to succeed.

Here are some tips on how you can do it right.

  • Choose a topic for your research and do some preliminary reading. Search for some interesting facts and try to think about new ways to address your topic. Scan some articles and look for knowledge gaps.
  • Take notes when you see an interesting quote and create a list of your sources. You can use them as references in your essay. Keep all the information you have gathered in one place.
  • Write down the objective of your essay in one sentence. Think about the outcome you want to achieve when other people read your essay.
  • Look through your notes and make a list of all the important points you want to make. Use brainstorming techniques and write down all ideas that pop into your head.
  • Review the points and create a thesis statement for depression research paper or essay.
  • Organize the list of points to create a structure of your essay . Put the points in a logical order. Check all aspects to make sure that each of them is relevant to your objective.
  • Revise all your points and try to put your outline in a standard format: numbered or bulleted list.

Depression essay introduction: how to start?

The introduction of your essay should provide some context and prepare your readers for the arguments you would present next.

Start your introduction with an attention grabber to engage your audience. It can be a provocative question, statistics, an anecdote, an interesting fact, etc.

Introduce your specific topic and provide some context to help your readers understand your paper. For example, you can define some key terms.

Finish your introduction with a strong thesis statement that clearly and concisely states the central argument or the purpose of your paper.

e.g., Students who drop out of a high school before graduation are more susceptible to depression and anxiety and have a higher risk of facing mental and physical health problems later in life.

You may also briefly outline the major points of your paper to help your audience follow your argument.

Depression essay conclusion: what should be included?

The conclusion is the last chance to impress your readers so it can be the most challenging part of an essay to write.

It should give your paper a sense of completeness and answer the question, “so what?”

You need to restate your main claim and tie that claim to a larger discussion. Don’t introduce any new ideas or subtopics here.

You can conclude your paper using one of the following strategies:

  • Call for a specific action.
  • Outline next steps for other researchers.
  • Speak about future implications.
  • Compare different situations or issues.
  • Use a quotation.
  • Ask a provocative question.

The use of depression essay example

A good essay example may help you understand how your project must be written. You can find a lot of essay examples online or order a well-written example from a professional writer.

You should read it and analyze what strategies and techniques are used to convey the main ideas and make an impression on readers.

Besides, you can get a better understanding of how you can structure your paper and what transitions you can use to ensure a logical flow of ideas.

Essay on depression: what to cover?

Writing about depression in college essay can involve a lot of different topics, especially those connected with the epidemic of mental disorders in teens.

For example, you may write causes of teenage depression essay and discuss multiple factors that create chemical imbalances in the human brain which may result in mental disorders and lead to such symptoms like anger, irritability, and agitation:

  • Biological factors – family history of mental disorders.
  • Social factors – loneliness and isolation, lack of meaningful relationships with family or peers.
  • Behavioral factors – alcohol or drug abuse.
  • Psychological factors – early childhood trauma, recent stressful experiences like a death in the family.

TOP-10 depression essay topics

  • Effects of mood disorders on physical health.
  • Causes of depression among teens.
  • Compare depression and bipolar disorder.
  • Neurodegenerative effects of long-term depression.
  • Mental disorders and personality changes in adults.
  • Impact of psychological stress on mental disorders.
  • Teen depression and suicide.
  • Depression symptoms in children and adults.
  • Are we witnessing an epidemic of serious mood disorders?
  • Digital media and mental disorders in children.

Argumentative essay on depression: how to prove you’re right?

Argumentative essay on depression is a more complex task because you need to take a stance and create a convincing argument to persuade your readers and make them accept your point of view or take a specific action.

You need compelling evidence to support your claims and main points.

Consult credible online sources, for example, a website of the American Psychiatric Association, to find some facts or statistics about mental disorders or news about current research on the topic.

Review some statistics which you can use to support your argument.

  • According to estimates, about 15% of adults experience depressive episodes in their lifetime.
  • About 5% of the US population experience seasonal depression every year.
  • The most “depressed” countries in the world are the USA, France, the Netherlands, Ukraine, and Colombia.
  • Japan has one of the lowest depression rates in the world, but it has one of the highest suicide rates, which is one of the leading causes of death among Japanese teens.
  • 4.8% of men and 8.5% of women suffer from depression in the USA.
  • The median age of people experiencing a major depressive episode is 32.
  • More than 44,000 American commit suicide each year and it’s the 2nd leading cause of death for young people aged from 15 to 24.

Argumentative essay topics about depression

  • Is there any correlation between burnout, depression, and anxiety?
  • How to deal with a crisis when living with mental disorders?
  • Is it common to have both anxiety and depression at the same time?
  • Can sleep deprivation cause mental disorders?
  • Is there any relationship between the consumption of certain food and mental disorders?
  • Can food help with overcoming anxiety?
  • Social media obsession and mental health issues.
  • Why do a lot of teens struggle with mental disorders?
  • Can exercise treat mental health issues?
  • How can we tell the difference between grief and depression?

Feel free to choose any of these interesting topics and write your own depression essay.

Although mental disorders are a complicated thing to write about, you are much likely to successfully cope with this challenging task if you follow our easy guidelines.

Depressed with the task to write depression? Forget the anxiety! Order your paper within three clicks and enjoy the bright side of life!

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  • v.20(3); Fall 2021

PhDepression: Examining How Graduate Research and Teaching Affect Depression in Life Sciences PhD Students

Logan e. gin.

† Research for Inclusive STEM Education Center, School of Life Sciences, Arizona State University, Tempe, AZ 85281

Nicholas J. Wiesenthal

§ Department of Biology, University of Central Florida, Orlando, FL 32816

Katelyn M. Cooper

Graduate students are more than six times as likely to experience depression compared with the general population. However, few studies have examined how graduate school specifically affects depression. In this qualitative interview study of 50 life sciences PhD students from 28 institutions, we examined how research and teaching affect depression in PhD students and how depression in turn affects students’ experiences teaching and researching. Using inductive coding, we identified factors that either positively or negatively affected student depression. Graduate students more commonly mentioned factors related to research that negatively affected their depression and factors related to teaching that positively affected their depression. We identified four overarching aspects of graduate school that influenced student depression: the amount of structure in teaching and research, positive and negative reinforcement, success and failure, and social support and isolation. Graduate students reported that depression had an exclusively negative effect on their research, primarily hindering their motivation and self-confidence, but that it helped them to be more compassionate teachers. This work pinpoints specific aspects of graduate school that PhD programs can target to improve mental health among life sciences graduate students.

INTRODUCTION

In 2018, researchers found that graduate students were more than six times as likely to report experiencing depression and anxiety compared with the general population and subsequently declared a “graduate student mental health crisis” ( Evans et al. , 2018 ; Flaherty, 2018 ). Calls to identify which factors exacerbate graduate student mental health problems followed (“The Mental Health of PhD Researchers,” 2019; Woolston, 2019a ). However, few studies have taken an inductive approach to identifying what aspects of graduate school in particular affect student mental health. More commonly, large quantitative studies propose a limited number of factors that may affect student mental health that participants select from, few of which directly relate to graduate research or teaching ( Peluso et al. , 2011 ; Levecque et al. , 2017 ; Evans et al. , 2018 ; Liu et al. , 2019 ). In this interview study, we focus on depression in life sciences PhD students and examine which specific aspects of research and teaching graduate students report as affecting their depression. We also explore how depression affects students’ experiences in graduate school.

The American Psychiatric Association defines depression as a common and serious medical illness that negatively affects how one feels, the way one thinks, and how one acts ( American Psychiatric Association, 2020 ). Depression is characterized by nine symptoms: depressed mood; markedly diminished interest or pleasure in activities; reduced ability to think or concentrate, or indecisiveness; feelings of worthlessness, or excessive or inappropriate guilt; recurrent thoughts of death or suicidal ideation, or suicide attempts or plans; insomnia or hypersomnia; significant change in appetite or weight; psychomotor agitation or retardation; and fatigue or loss of energy ( American Psychiatric Association, 2013 ; Schmidt and Tolentino, 2018 ). For depression to be diagnosed, the presence of at least five of the symptoms is required most of the day, nearly every day, for at least 2 weeks in addition to the occurrence of either depressed mood or diminished interest or pleasure ( American Psychiatric Association, 2013 ). In the general U.S. population, depression affects approximately 6.7% of individuals and is estimated to affect 16.6% of individuals at some point in their lifetime.

Graduate students are far more likely to report experiencing depression compared with the general population ( Evans et al. , 2018 ; Barreira et al. , 2020 ). Specifically, a recent study of master’s and PhD students in programs across the world, spanning a variety of disciplines, found that 39% of graduate students reported having moderate to severe depression ( Evans et al. , 2018 ). Similar studies have demonstrated high rates of depression in graduate students in specific disciplines such as economics ( Barreira et al. , 2020 ), biochemistry ( Helmers et al. , 1997 ), pharmacology ( Helmers et al. , 1997 ), and physiology ( Helmers et al. , 1997 ). Depression rates have surged in recent years among graduate students ( American College Health Association, 2014 , 2019 ). Talking about depression has become more socially acceptable, particularly among younger adults ( Anxiety and Depression Association of America, 2015 ; Lipson et al. , 2019 ), which may have contributed to the number of students willing to reveal that they are struggling with mental health. Additionally, depression is highly related to burnout, defined as a work-related chronic stress syndrome involving emotional exhaustion, depersonalization, and reduced personal accomplishment ( Maslach et al. , 2001 ; Bianchi et al. , 2014 ). Graduate work environments appear to be increasingly characterized as stressful and demanding ( American College Health Association, 2014 , 2019 ; Woolston, 2017 ), which may also be contributing to the increase in graduate depression rates.

Increasingly, scientists, psychologists, and education researchers are recognizing graduate student mental health as a concern and calling for further investigation of graduate student mental health in hopes of identifying interventions to improve graduate student quality of life (“The Mental Health of PhD Researchers,” 2019; Woolston, 2019a , b ). For example, in 2019, Nature added a question to its annual survey of PhD students asking students from around the world whether they had sought help for anxiety or depression, and more than one-third (36%) confirmed they had ( Woolston, 2019b ). Additionally, notable publication outlets such as Nature (“The Mental Health of PhD Researchers,” 2019), Scientific American ( Puri, 2019 ), and Science ( Pain, 2018 ) have published blogs or editorials spotlighting the need to improve graduate student mental health.

Some recent studies have sought to uncover the factors affecting depression in graduate students. Primarily, survey studies with predetermined factors that researchers hypothesized impact student mental health have identified poor mentor–mentee relationships ( Peluso et al. , 2011 ; Evans et al. , 2018 ; Hish et al. , 2019 ; Liu et al. , 2019 ; Charles et al. , 2021 ), financial stress ( Hish et al. , 2019 ; Jones-White et al. , 2020 ; Charles et al. , 2021 ), and lack of work–life balance ( Evans et al. , 2018 ; Liu et al. , 2019 ) to be associated with depression or depressive symptoms among graduate students in various disciplines. Other variables shown to be predictive of depression include low research self-efficacy, defined as low confidence in one’s ability to do research ( Liu et al. , 2019 ), difficulty publishing papers ( Liu et al. , 2019 ), hours worked per week ( Peluso et al. , 2011 ), and perceived institutional discrimination ( Charles et al. , 2021 ). Factors that appear to be protective of depressive symptoms include social support ( Charles et al. , 2021 ), mastery, defined as the extent to which individuals perceive themselves to be in control of the forces that impact their lives ( Hish et al. , 2019 ), positive departmental social climate ( Charles et al. , 2021 ), optimism about career prospects ( Charles et al. , 2021 ), and sense of belonging to one’s graduate program ( Jones-White et al. , 2020 ). While these studies have identified some depression-related factors associated with graduate school broadly and emphasize the importance of positive mentor–mentee relationships, few studies have explored factors specifically associated with research and teaching, the two activities that graduate students engage in most frequently during their time in a program. Additionally, the extant literature has primarily focused on surface causes of graduate student depression, yet understanding the underlying causes may be key to developing meaningful interventions. For example, while it is well established that student perception of poor mentorship is related to student depression ( Evans et al. , 2018 ; Hish et al. , 2019 ; Liu et al. , 2019 ; Charles et al. , 2021 ), it is less well understood what specific behaviors mentors exhibit and how such behaviors negatively affect the cognitive and behavioral underpinnings of graduate student depression. Without this knowledge, it is difficult to develop strategies to help mentors be more inclusive of students.

Theories of depression seek to explain the causes of depression. No theoretical model is widely accepted as an overarching framework for depression within the psychological and psychiatric communities ( Mcleod, 2015 ; Ramnerö et al. , 2016 ); instead, there are a number of models addressing how different aspects of depression are associated with the disorder. Arguably, the three most prominent models are cognitive ( Beck et al. , 1979 ), behavioral ( Martell et al. , 2001 ), and psychodynamic ( Busch et al. , 2016 ). In brief, cognitive theories focus on an individual’s beliefs and propose that changes in thinking precede depressive symptoms; for example, negative views of oneself, the world, and the future are thought to be common for individuals with depression ( Beck et al. , 1979 ; Leahy, 2002 ). Behavioral theories emphasize that depression is a result of one’s interaction with the environment; depressive symptoms are thought to be the result of decreased reward, lack of positive reinforcement, encouragement of depressive or passive behaviors, and discouragement of healthy behaviors ( Lewinsohn, 1974 ; Martell et al. , 2001 ; Carvalho et al. , 2011 ). Psychodynamic theories of depression consider the role of feelings and behaviors in the etiology and persistence of depressive symptoms; these theories often focus on 1) one’s biology and temperamental vulnerabilities, 2) earliest attachment relationships, and 3) childhood experiences associated with frustration, helplessness, loss, guilty, or loneliness ( Busch et al. , 2016 ). While each group of theories has been critiqued and no one theory fully explains one’s experience with depression ( Mcleod, 2015 ; Ramnerö et al. , 2016 ), we propose that each may be helpful in understanding how aspects of graduate school may affect depression among PhD students.

The thoughts and behaviors associated with depression may in turn affect students’ experiences in graduate school, particularly their experiences with research and teaching. While no studies have examined how depression explicitly affects graduate students’ research experiences, studies have identified ways in which depression can affect students’ experiences in undergraduate research ( Cooper et al. , 2020a , b ). Undergraduate researchers report that their depression negatively affected their motivation, ability to concentrate and remember, intellectual engagement, and creativity in research ( Cooper et al. , 2020b ). Undergraduates described that their depression also caused them to be overly self-critical, less social, and ultimately negatively affected their research productivity. Additionally, undergraduates have been reluctant to share their depression with others in the lab, because they fear that they will be judged ( Cooper et al. , 2020b ). While these studies provide some insight into how depression may affect graduate students’ experience in research, there is much less information about how depression may affect graduate teaching.

In this study, we interviewed 50 PhD students in the life sciences who self-identified with having depression with the intent of answering two research questions that address gaps in the literature: 1) What specific aspects of graduate research and teaching affect PhD student depression? 2) How does PhD students’ depression affect their experience in research and teaching?

Student Interviews

This study was done under an approved Arizona State University Institutional Review Board protocol (no. 00011040).

In Fall 2019, we surveyed graduate students by sending an email out to program administrators of all life sciences graduate programs in the United States that are listed in U.S. News & World Report (2019) . Of the 259 graduate programs that we contacted, 75 (29.0%) program administrators agreed to forward our survey to students enrolled in their graduate programs. Of the 840 graduate students who participated in the survey, 459 (54.6%) self-identified as having depression based on general demographic questions on the survey. Of the 459 students who identified as having depression, 327 (71.2%) agreed to be contacted for a follow-up interview. In Summer 2020, we sent a recruitment email out to the 327 students who identified as having depression, asking to interview them about their experiences with depression in a PhD program. We specifically did not require that students be diagnosed with depression in order to participate in the interview study. We did not want to bias our sample, as mental health care is disproportionately unavailable to Black and Latinx individuals, as well as to those who come from low socioeconomic backgrounds ( Howell and McFeeters, 2008 ; Kataoka et al. , 2002 ; Santiago et al. , 2013 ). Of the students who were contacted, 50 PhD students (15.3%) enrolled across 28 life sciences PhD programs completed an interview.

The interview script was based on a previous interview script that we had developed, which successfully elicited what aspects of research affect depression in undergraduates and how depression affects their research ( Cooper et al. , 2020a ). Our previous work has shown that research experiences do not exclusively worsen depression, but that aspects of research can also help students manage their depression ( Cooper et al. , 2020a ). As such, our interview questions explored what aspects of research helped students manage their depression (positively affecting depression), and what aspects worsened students’ depression (negatively affecting depression). Additionally, we hypothesized that other prominent aspects of graduate school, such as teaching, would also affect PhD student depression and revised the interview script to include questions focused on examining the relationship between depression and teaching. We asked students what aspects of graduate research and teaching made their depression worse and what aspects helped them manage their depression. Participants were invited to come up with as many aspects as possible. We also asked how students perceived their depression affected their research and teaching. With the knowledge that we would be conducting interviews during summer of 2020 in the midst of the COVID-19 pandemic, and that the pandemic had likely exacerbated graduate student depression ( Chirikov et al. , 2020 ), we directed students to not reference aspects of research and teaching that were uniquely related to the pandemic (e.g., teaching remotely or halted research) when discussing the relationship between research, teaching, and depression. We were specifically interested in aspects of teaching and research that affected student depression before the pandemic and would presumably affect student depression afterward. We conducted think-aloud interviews with four graduate students who identified as having depression to ensure that our questions would not offend anyone with depression and to establish cognitive validity of the interview script by ensuring that each student understood what each question was asking. The interview script was iteratively revised after each think-aloud interview ( Trenor et al. , 2011 ). A final copy of the interview script can be found in the Supplemental Material.

All interviews were conducted using Zoom by one of two researchers (L.E.G. or K.M.C.). The average interview time was about 45 minutes. After the interview, all participants were sent a short survey to collect their demographics and additional information about their depression (a copy of the survey can be found in the Supplemental Material). Participants were provided a small monetary gift card in exchange for their time. All interviews were deidentified and transcribed before analysis.

Interview Analysis

Three researchers (L.E.G., N.J.W., and K.M.C.) independently reviewed 12 of the same randomly selected interviews to explore each idea that a participant expressed and to identify recurring themes ( Charmaz, 2006 ). Each researcher took detailed analytic notes during the review. After, the three researchers met to discuss their notes and to identify an initial set of recurring themes that occurred throughout the interviews ( Saldaña, 2015 ). The authors created an initial codebook outlining each theme and the related description. Together, the authors then reviewed the same set of five additional interviews to validate the themes outlined in the codebook and to identify any themes that may have been missed during the initial review. The researchers used constant comparison methods to compare quotes from the interviews to each theme and to establish whether any quotes were different enough from a particular theme to warrant an additional code ( Glesne and Peshkin, 1992 ). Together, the three researchers revised the codebook until they were confident that it captured the most common themes and that no new themes were emerging. A final copy of the codebook can be found in the Supplemental Material. Two authors (L.E.G. and N.J.W.) used the final codebook to code five randomly selected interviews (10% of all interviews) and their Cohen’s κ interrater score was at an acceptable level (κ = 0.94; Landis and Koch, 1977 ). Then, one researcher (N.J.W.) coded the remaining 45 interviews. In the text, we present themes mentioned by at least 10% of interviewees and use quotes to highlight themes. Some quotes were lightly edited for clarity.

Author Positionality

Some of the authors identify as having depression and some do not. One author had completed a PhD program (K.M.C.), one author was in the process of completing a PhD program (L.E.G.), and two authors were undergraduates (N.J.W. and I.F.) at the time when the interviews and analyses took place.

Interview Participants

Fifty PhD students agreed to participate in the study. Students were primarily women (58%), white (74%), and continuing-generation college students (78%). Twelve percent of students were international students, and the average age of the participants was 28 years old. While 20% of students were unsure of their career goals, 32% of students planned to pursue a career in academia, and 24% were planning to pursue a career in industry. Students reported how severe they perceived their depression to be, on average, during the time they had spent in their PhD programs. Most students reported their depression as either moderate (50%) or severe (28%). Eighty percent of students reported being diagnosed with depression, and 74% reported receiving treatment for depression. Participants were at different stages in their PhD programs ranging from first year to sixth year or more. Three students had graduated between the time they completed the initial survey and when they participated in the interview in Summer 2020. Students self-reported their main research areas and represented a broad range, with ecology and evolutionary biology (26%), animal science (14%), molecular biology (14%), and neurobiology (10%) being the most common. Eighty-six percent of students had experience teaching undergraduates, primarily as teaching assistants (TAs), at the time of the interviews. All student demographics are summarized in Table 1 .

Participant demographics

Student-level demographicsInterview participants ( = 50) (%)Research/teaching demographicsInterview participants ( = 50) (%)Depression demographicsInterview participants ( = 50) (%)
Gender Program year Severity of depression during graduate school
 Woman29 (58) First year4 (8) Mild7 (14)
 Man17 (34) Second year13 (26) Moderate25 (50)
 Nonbinary/gender fluid4 (8) Third year12 (24) Severe14 (28)
Race/ethnicity  Fourth year5 (10) Extremely severe4 (8)
 Asian/Pacific Islander4 (8) Fifth year7 (14) Diagnosed with depression
 Black/African American1 (2) Sixth year or more6 (12) Yes40 (80)
 Hispanic/Latinx4 (8) Recently graduated3 (6) No8 (16)
 White/Caucasian37 (74) Focus area of research  Decline to state2 (4)
 One or more race/ethnicity3 (6) Animal science7 (14) Treated for depression
 Decline to state1 (2) Biochemistry3 (6) Yes37 (74)
College generation status  Biological anthropology1 (2) No11 (22)
 First generation11 (22) Biology education1 (2) Decline to state2 (4)
 Non–first generation39 (78) Ecology/evolutionary biology13 (26) Treatment methods for depression
International status  Environmental and conservation biology2 (4) Medication3 (6)
 Yes6 (12) History and philosophy of science1 (2) Therapy/counseling12 (24)
 No44 (88) Immunology4 (8) Both medication and therapy/counseling21 (42)
Age  Microbiology1 (2) Decline to state14 (28)
 Mean (SD)28 (3.4) Molecular biology and genetics7 (14)
 Range23–40 Neurobiology5 (10)
Career goal  Physiology2 (4)
 Academia16 (32) Plant science3 (6)
 General research assistant8 (16) Teaching experience
 Industry12 (24) Yes43 (86)
 Science policy4 (8) No7 (14)
 Undecided10 (20)

The Effect of Research on Graduate Student Depression

Students more commonly identified ways that research negatively affected their depression than ways research positively affected their depression. Considering all factors that students listed and not just those that were most common, students on average listed two ways in which an aspect of research negatively affected their depression and one way in which an aspect of research positively affected their depression.

The most commonly reported aspect of research that worsened students’ depression was experiencing failures, obstacles, or setbacks in research. Specifically, students cited that failed experiments, failed research projects, and the rejection of manuscripts and grants was particularly difficult for their depression. Conversely, students highlighted that their depression was positively affected when they were able to make substantial progress on their research projects; for example, if they wrote part of a manuscript or if an experiment worked. Students also explained that accomplishing smaller or mundane research tasks was helpful for their depression, both because they felt as though they were checking off a box and also because it allowed them to focus on something other than the negative thoughts often associated with depression.

Students also highlighted that the unstructured nature of graduate research worsened their depression. Specifically, students described that, in graduate research, there are often no clear directions, sets of guidelines, or deadlines to help structure their day-to-day activities. Without this structure, students need to rely on their own motivation to outline goals, accomplish tasks, or seek help, which participants described can be difficult when one is experiencing a depressive episode. However, students also felt as though the unstructured nature of research benefited their depression, because it allowed for flexibility. Those who did not have frequent deadlines or strict schedules were able to not conduct research on days when they needed to recover from a depressive episode or schedule research around therapy or other activities that had a positive impact on their depression. Finally, students highlighted that their passion for their research was protective against depression. Their love for the subject of their research or thinking about how their work may have a positive impact on others could positively affect their motivation or mood.

Students described that their relationships with others in the lab also affected their depression. Specifically, if their mentors or others in their lab had unreasonable or overwhelming expectations of them, it could make them feel as though they would never be able to meet such expectations. Research also provides an environment for students to constantly compare themselves with others, both those in supervisory roles as well as peers. Notably, when students mentioned comparing themselves with others, this comparison never made them feel good about themselves, but was exclusively detrimental to their depression; they felt as though they would never be able to accomplish what others had already accomplished. Students’ relationships with their mentors also seemed to have a notable impact on their depression. Having a positive relationship with their mentors or a mentor who provided psychosocial support positively affected their depression, whereas perceiving a negative relationship with their mentors, particularly a mentor who provided consistently harsh or negative feedback, was detrimental. Students who had absent mentors or mentors who provided infrequent technical support and guidance also felt as though this situation worsened their depression, because it prevented or prolonged their success in research. Finally, students highlighted that conducting graduate research can be isolating, because you are often working on something different from those in the lab or because those outside graduate school cannot relate to the stress and struggles associated with research. However, in instances in which students were able to collaborate with others, this could be protective against depression, because it gave students a sense of comradery or validated their feelings about specific aspects of research. The most common research-related factors that students reported negatively and positively affected their depression and example student quotes of each factor are reported in Tables 2 and ​ and3, 3 , respectively.

Research-related factors that PhD students reported negatively affected their depression

FactorDescription% ( ) ( = 50)Example quoteExample quote
Failures, obstacles, or setbacks during researchExperiencing failure, obstacles, or setbacks in graduate school can negatively affect student depression. This commonly includes experiencing failed experiments or failed research projects, rejections of grant proposals, or rejections of papers.48 (24)Student 20: “Everything just fails and you have zero positive results and nothing you can publish. That was one of the worst things for me. The stress of knowing that you are not succeeding is really bad [for depression].”Student 5: “I could do everything perfectly and for one reason or another the whole project could just fail. So, I think the breakdown of that link between my actions and the outcome, that was hard.”
Unstructured research experiencesResearch experiences that are unstructured, that is, they do not have a clear set of directions or deadlines to guide the work, can negatively affect student depression.38 (19)Student 34: “My depression has not enjoyed or been spared by the fact that research is self-directed. Finding the equipment, finding the questions, finding the method rests on me.”Student 12: “For me, I think the periods of time post-classes were a lot harder in terms of mental health, where there aren’t as many external deadlines. You’re mostly driven by your own goals and ambitions every day. (…) But when [goals and ambitions] are dropped, it’s really easy for depression to kick in.”
Negative reinforcementNegative reinforcement from others in research such as harsh criticism, feedback, comments, or reviews about one’s research or performance can negatively affect student depression.34 (17)Student 26: “[Your mentor] will tell you how poorly you’re doing to inspire you to work harder, and that’s not something that works with me, because I already see everything that I’m doing wrong, and all the problems in a project, so I don’t need a mentor that points out those problems to me again, because I’m like, ‘Yeah, I [expletive] know all the problems! I should just quit, right?’”Student 7: “You say something stupid and your PI (principal investigator) suddenly says how stupid that is. And then all that just [makes me think] ‘I’m an idiot, I can’t do it.’”
Unreasonable or overwhelming expectationsMentors or others in research who place too high of expectations on students, particularly related to the progress that they are making in research, can negatively affect student depression.34 (17)Student 4: “My [previous] advisor had really high expectations and was really pushy. It really exacerbated my depression a lot, because I felt like I could never live up to the expectations.”Student 29: “I think when I’m working hard and where my hours are going doesn’t necessarily make sense to my advisor [it affects my depression]. I’m like, ‘No, I’m working, I’m working, I’m working.’ And then they’re like, ‘Well, but maybe work harder.’ That feels pretty bad.”
Opportunity to compare self to othersWhen students compare their success in research to others’ success, it can negatively affect their depression.28 (14)Student 24: “I think that I’m a huge person that compares themselves to others. When I hear others speak about their research or their progress, though it may not be light years away from mine, it feels that way. I get sad. I feel like I’m not where I’m supposed to be or that I don’t deserve to be where I’m at compared to others.”Student 44: “Sometimes I see my other cohort students succeeding and not even in a jealous way necessarily, but I do measure myself against them. If I haven’t gotten my first author publication yet or whatever, that means I’m behind the curve. I think part of [my depression] is just comparing myself to others.”
Lack of technical support or guidanceNot receiving adequate support or guidance in research can negatively affect student depression.22 (11)Student 18: “I’ve experienced my PI being very absent. And so, not having that touchstone of advice like, ‘Stop now, maybe stop while you’re ahead, or maybe you can change this,’ and then wasting all that time or feeling like I’ve wasted all that time can make it harder [on my depression].”Student 49: “You get thrown in the deep end on projects, and the lab has been so busy that there’s been no support. So, if you fall a little flat, then it’s just all on you where they’re like, ‘Oh man, I wish I could help you out with that or give you this support,’ and I feel like I’ve been set up to fail a lot.”
Social isolationFeeling isolated when doing research, either because others in the lab or others outside graduate school cannot relate to specific stressors and experiences, can negatively affect student depression.18 (9)Student 8: “[Doing research] is very isolating because obviously not many people go for PhDs. I can’t talk to [my friends] about research struggles because they’re like, ‘OK, how do I fix that? You did that to yourself.’ And I’m like, ‘I mean, you’re right, but…’ Nobody understands you.”Student 20: “I think that’s one thing [that affects my depression], when it comes to research, it’s quite a lonely experience sometimes when you’re working on your own project and everybody else has their own project. They have their own worries to think about and all you are stressing about is your own thing.”

Research-related factors that PhD students reported positively affected their depression

FactorDescription% ( ) ( = 50)Example quoteExample quote
Completing small or concrete research tasksCompleting small or concrete research tasks helps students feel like they have accomplished something or distracts their mind from negative thoughts, which can positively affect student depression.26 (13)Student 24: “When I’m doing wet lab work I’m in the zone, [it is good for my depression]. When I’m in that mode, it doesn’t allow me to be depressed, because I’m too busy to really overthink things.”Student 35: “I have a very simple goal, which is to collect my data and that’s all I think about for the entire day. I’m hiking, I’m listening to audio books, whatever. And so, there’s literally just no time for me to get caught up in my own mind.”
Working with othersInteracting with others can positively affect student depression.22 (11)Student 43: “Working collaboratively with other students and working consistently with faculty helps a lot [with my depression].”Student 20: “Friends, obviously, colleagues, people who share the same sentiment [help my depression]. It’s amazing to have people right next to you say, ‘Don’t worry about it, this happens to everyone. Try this, try that.’”
Passionate about research topicFeeling passionate about their research topic or caring about the potential impact of research can positively affect student depression.18 (9)Student 10: “I love vaccines, I love immunology, I love recombinant genetic engineering. That in itself actually does help [my depression] a lot because I get to learn more every day. (…) That absolutely helps [my depression] because it drives me.”Student 25: “I study plants and I really love plants and being around them. And so that’s been the best part is getting to work with plants in the greenhouse, and that feels helpful [for my depression].”
FlexibilityFlexibility in research allows students to feel as though they have control over their time and they can prioritize their mental health (e.g., by going to therapy or taking a mental health day) when necessary, which can positively affect student depression.18 (9)Student 12: “I can schedule therapy whenever. I’m not confined to a specific nine-to-five workday. (…) If I wake up one day and I’m really struggling, I can shift my weekends. I can be like, ‘All right. Today I need to take care of me,’ and then maybe I’ll work an extra day of the weekend if I need to catch up or something. So that flexibility can be really supportive.”Student 47: “Some jobs, you have to be there, whereas with grad school if I’m having a really bad day and I really feel like I can’t handle being in the lab, it’s a little easier for me to not have to be there or for me to rearrange my schedule so I’m doing [tasks] that are a little bit less stressful for me.”
Research progressMaking significant progress in research can positively affect student depression.16 (8)Student 46: “I will say [something that helps my depression] is when you are working really hard on the experiment, on the goal, and then finally you get something, when you get good data. This makes all of my effort worth it.”Student 1: “Making progress helps me feel less [depressed], when I am getting a lot of data. I never feel stressed about my productivity at those points in time.”
Emotionally supportive PIA positive mentor relationship, which often involves psychosocial support, can positively affect student depression.12 (6)Student 23: “Things that help [my depression] are having a supportive PI who you’re able to talk to about your mental illness, and who’s understanding.”Student 38: “If I didn’t have the advisors that I have now, I don’t know that I would be able to proceed through getting a PhD, because I have been able to be very open with them about my mental health struggles and the reality of how mental illness affects me and affects my life and my productivity. And they haven’t really rigorously pushed me beyond my stated limitations.”

The Effect of Teaching on Graduate Student Depression

We asked all graduate students who had teaching experience ( n = 43) how teaching affected their depression. Graduate students more commonly identified ways that teaching positively affected their depression than ways teaching negatively affected their depression. On average, considering all factors that graduate students listed and not just those that were most common, participants listed two ways in which teaching positively affected their depression and one way in which teaching negatively affected their depression.

Graduate students most commonly highlighted that teaching provided positive reinforcement from undergraduates, which helped them manage their depression. This positive reinforcement came in multiple forms ranging from formal teaching evaluations to positive verbal comments from undergraduates about how good a graduate student was at teaching to watching undergraduates accomplish academic goals or grasp complex concepts. A subset of graduate students highlighted that teaching was good for their depression, because it was something they were passionate about or that they genuinely enjoyed. As such, it was a source of happiness, as was being able to collaborate and form friendships with other TAs or instructors. Some graduate students also acknowledged that they felt confident teaching, often because they had mastered content that undergraduates had not. However, this was not always the case; some graduate students highlighted that a lack of teaching training and preparation negatively affected their self-efficacy as instructors, which in turn exacerbated their depression. This was further exacerbated by the pressure that graduate students put on themselves to perform well as instructors. The potential to have a negative impact on undergraduates and their learning experiences could worsen students’ depression by increasing the stress surrounding their performance as a teacher. Additionally, some graduate students received negative reinforcement from undergraduates, in the form of negative comments on formal teaching evaluations or disrespectful behavior from undergraduates such as groans or eye rolls, which graduate students explained negatively affected their self-efficacy, further worsening their depression.

Students also highlighted that teaching could negatively affect their depression because it interfered with the time they felt they needed to be spending on research or added to the large number of responsibilities they had as graduate students. However, some students welcomed time away from research; teaching sometimes served as a distraction from research-related stressors. Students also highlighted that teaching is structured, which positively affected their depression. That is, there are concrete tasks, such as grading, that need to be accomplished or places that the graduate student needs to be during a specific time. This structure helped motivate them to accomplish teaching goals, even if they were feeling a lack of motivation because of their depression. The most common teaching-related factors that graduate students reported negatively and positively affected their depression and example student quotes for each factor are reported in Tables 4 and ​ and5, 5 , respectively.

Teaching-related factors that PhD students reported negatively affected their depression

FactorDescription% ( ) ( = 43) Example quoteExample quote
Increases number of responsibilities/time away from researchTeaching adds to the total number of responsibilities that graduate students have and can interfere with the time that they feel they need to spend on research, which increases stress and can negatively affect student depression.47 (20)Student 10: “As a PhD student, you’re expected to publish, do all this research, and then also teach. A little while ago, I was both designing a class and teaching two sections at the same time, and I was spending so much time on that class. It was close to 40 hours per week plus research. I definitely was feeling overwhelmed, and I do think that can affect [my depression], because it leads to burnout.”Student 12: “Teaching often regularly leaves you with less time to focus on research. So, it is time away from research. And if I’m already feeling like I’m not doing enough, having the extra load of teaching can just amp that feeling up.”
Negative reinforcement from undergraduatesNegative reinforcement from undergraduates, in the form of being rude, disrespectful, or disengaged, or receiving negative scores and comments on teaching evaluations, can negatively affect student depression.28 (12)Student 29: “It [is hard for my depression] and really bums me out when [the undergraduates] don’t try. I put a lot into [teaching]. (…) The ones that are just like, ‘I don’t want to do this,’ and roll their eyes, it’s just hard. It’s like, I put so much into making [the content] clear and I’m trying. So, when the students are not really trying, it does not feel great.”Student 19: I’ve had students straight up tell me, ‘This is the least important class that I have to take this semester. I’m not going to put in much effort.’ And it makes me feel kind of crummy, kind of bad. When at the end of the semester, I get the teaching evaluations saying, ‘I just took this class because I need it or I had to. I didn’t think it added anything to my education.’ I feel very low.”
Personal pressure to teach wellFeeling an obligation to teach undergraduates well or ensure that they understand the course content can induce stress and negatively affect depression.26 (11)Student 16: “[My depression related to teaching] all comes back to the stress of having to do a good job for my students. I didn’t want to fail them. So that was difficult and I took [being a teacher] very seriously.”Student 40: “I think feeling like there were these undergrads depending on me [negatively affected by depression]. (…) If I haven’t sufficiently prepared to lead a discussion section or whatever, there are undergrads whose education will suffer. That added pressure was hard [on my depression] and just being afraid of letting them down.”
Lack of teaching training or guidanceNot having training or guidance about how to teach made students feel insecure about their teaching abilities, which can negatively affect their depression.16 (7)Student 25: “[My depression worsened] because I was concerned about the lack of supervision and the lack of support for how to teach. (…) I just felt like I was doing a terrible job, which was really discouraging.”Student 26: “I didn’t feel like I had enough guidance as to what I should be teaching [the undergraduates in my class] and how to control a classroom, so not having the respect of the students and not knowing how to get it was really stressful.”

a Forty-three out of the 50 students who participated in the study had experience teaching undergraduates either as a TA or as an instructor of record. We only considered the responses from the TAs with teaching experiences when calculating the percent of students who reported each factor.

Teaching-related factors that PhD students reported positively affected their depression

FactorDescription% ( ) ( = 43) Example quoteExample quote
Positive reinforcement from undergraduatesPositive reinforcement from undergraduates, in the form of positive verbal comments, positive comments on formal evaluations, or watching undergraduates grasp a concept or get excited about content, can positively affect student depression.58 (25)Student 15: “What really helped me during those depressive times were that my students would say like, ‘Sulfates in my shampoo, they’re not good for the water. I learned that from you.’”Student 5: “Interacting with my undergraduates and feeling like I made a difference for them [helps my depression]. Even if it was just something as simple as them saying like, ‘Oh, wow [Student 5], I feel like I actually really get this now,’ or ‘I did better on this exam after we went over material together.’”
Teaching as a structured taskThe structured nature of teaching, including having concrete tasks to accomplish and specific places to be at specific times, can positively affect student depression.33 (14)Student 27: “Sometimes having concrete tasks does [help my depression]. With research, you never have deadlines or things that get accomplished or finished. Where at least with teaching, you can sit down and you can grade for three hours. You can do things.”Student 8: “I have to have the test made by the time class starts on an exam day. I have to make sure that I’m there on time and that I don’t go over time, things like that. So just having that kind of strict schedule, I think helped [my depression].”
Passion for teachingBeing passionate about teaching and enjoying teaching can positively affect student depression.30 (13)Student 48: “I’ve always enjoyed teaching. One main reason I did a PhD was to teach at the postsecondary level. So, for me, honestly, the experience of interacting with students is energizing, and does rejuvenate me a lot.”Student 15: “[Teaching] gave me motivation and kind of like a reason to keep going. I love science, but I love the access to science that I can give to other people.”
Distraction from researchTeaching can serve as a distraction from stressors related to research, which can positively affect student depression.23 (10)Student 42: “Research is tedious and difficult and honestly I have to admit I never really had fun with it. But teaching is kind of a way away from that. It’s something that you can still do and you can still contribute like you’ve got a good job and you’re doing things. (…) It helped take my mind off of the hardships of what was going on during research.”Student 4: “[Teaching] is a good respite from my research sometimes. It’s a different side to being in school.”
Confidence about teachingHaving confidence about teaching, specifically about being a good teacher or having mastery of the content, can positively affect student depression.14 (6)Student 42: “[Teaching] is helpful for my depression because, like I am sorry if this is cocky sounding, but I’m really good at teaching and when I go in to teach, it’s like, ‘I know that this is right.’”Student 50: “It’s good to feel like an expert in front of this group of undergrads. When you come from maybe a lab, or field experience where you feel like you don’t know what you’re doing, it can be very positively reinforcing working with undergrads.”
Positive relationships with others teachingHaving positive relationships with others involved in teaching, particularly other TAs or a lead instructor, can positively affect student depression.12 (5)Student 16: “[Teaching] was really helpful for my depression, because I made friends with the other TAs, especially during my first year as a TA, and we were all new.”Student 28: “I had a co-TA giving a lecture with me and he was a very nice person. So, we became friends. Yeah. It helped [my depression] a little bit.”

The Effect of Depression on Graduate Research

In the interviews, we asked graduate students how their depression affected their graduate research, if at all. They identified three primary ways in which depression could affect research, all of which were negative. The most common way depression affected research was interfering with students’ motivation, which in turn affected their productivity. Students described that their productivity was affected immediately, for example, struggling to execute daily tasks like collecting or analyzing data. However, graduate students described that their lack of motivation ultimately resulted in larger consequences, such as delays in getting papers submitted and published. In fact, some graduate students explicitly stated that they felt as though they would have been able to graduate earlier if they had not had depression. The second way in which depression affected graduate students’ research is that it interfered with their ability to focus or concentrate. Students primarily explained that the lack of focus did not delay their research but caused their research to be less enjoyable or made them frustrated because they had to expend additional mental energy to execute tasks. Depression also caused students to be less confident or overly critical of themselves. Specifically, if an experiment did not go right or they experienced rejection of a manuscript, they tended to internalize it and blame themselves. This lack of confidence often inhibited students’ abilities to make decisions about research or take risks in research. They described frequently second-guessing themselves, which made decisions and taking risks in research more difficult. The most common ways students reported that their depression affected their research and example student quotes are reported in Table 6 .

Self-reported ways that depression affected PhD students’ research or the student as a researcher

ThemeDescription% ( ) ( = 50)Example quoteExample quote
Lack of motivation and productivityDepression can make students feel less motivated to do research, which can result in a lack of productivity. This lack of productivity can range from not being able to analyze a data set to not being able to write and submit a paper.64 (32)Student 3: “When I’m really depressed and I’m trying to do something that’s pretty positive and challenging, like write a manuscript, it tends to be really difficult. I can go from, when I’m not depressed, banging out some really good work, and then when I become depressed, that definitely tanks.”Student 35: “[Depression] keeps me from doing the things that I want to do, like every single day and be consistent. Like reading a paper every day or writing for an hour every day and it’s just like, I am so exhausted that I feel like I can’t do that. It increases procrastination.”
Low self-esteem or overly self-criticalDepression can cause students to doubt their abilities as a scientist, be self-critical, internalize failure, take unnecessary responsibility for something that did not work, and be hyperaware of any issues they may be having.58 (29)Student 10: “Sometimes I feel I’m an imposter. Internally I know that I have intelligence, but then it’s like I don’t know if I can do it. Everything is harder, and then my research will suffer.”Student 19: “[My depression] brings on this imposter syndrome. Like, ‘What am I doing in this program?’ So, I’m constantly struggling and battling those thoughts. Never feeling that you fit in, struggling with, ‘Are you good enough? Is what you’re doing good enough? Should I stay in this program?’”
Difficulty focusing and concentratingDepression can cause students to be distracted or unfocused or to struggle to pay attention to detail, which can result in feelings of frustration and exhaustion.28 (14)Student 9: “Because I was going through kind of a mental instability, I was unable to actually focus on what I was actively doing in lab. I was kind of like a zombie going in to work and getting out every day.”Student 40: “The trouble concentrating just makes everything harder when you just can’t seem to sit down and focus and get things done. I would say it’s made grad school harder, more frustrating, and less enjoyable because I just constantly feel like I’m behind and not doing enough.”

The Effect of Depression on Teaching

Graduate students described one positive way and two negative ways that depression affected their teaching. Students explained that, because they had experienced depression, they were more compassionate and empathetic toward the undergraduates in their courses. Specifically, they felt they could better understand some of the struggles that undergraduates experience and were sometimes more likely to be flexible or lenient about course requirements and deadlines if an undergraduate was struggling. However, graduate students reported that depression also negatively affected their teaching. Specifically, depression could cause graduate students to feel disconnected or disengaged from undergraduates. It could also cause graduate students to feel as though they had a lack of energy or felt down when teaching. The common self-reported ways that depression affected PhD students’ teaching and example quotes are reported in Table 7 .

Self-reported ways that depression affected PhD students’ teaching or the graduate student as an instructor

FactorDescription% ( ) ( = 43) Example quoteExample quote
Negative effects on depression on graduate student teaching
Disconnected or disengaged from undergraduatesDepression can cause graduate students to feel disengaged when teaching or to have trouble connecting with undergraduates.16 (7)Student 18: “[When I have depression], I can feel disconnected from the [undergraduates]. I’ll go to my day of teaching, I lead these discussion sections and I’m going through the motions. I don’t really put my full heart into it in terms of going out of my way to connect with the [undergraduates] or being more enthusiastic.”Student 49: “But there were many days that my depression, through various avenues, caused me to be absentminded [while teaching]. (…) Just less attentive and [less] engaged.”
Felt down or lacked energy when teachingDepression can cause graduate students to be less energetic or to have a low mood when teaching.14 (6)Student 4: “There’s been times where I’ve just been unable to prep for classes, or have prepped very little, just because I’m just struggling with myself and trying to get through things. It upsets me, because I feel like I’m letting the undergrads down.”Student 13: “I’m sure [my students] have been able to tell when I’ve shown up to classrooms just depressed. And that’s not what they’re paying for, and they’re paying a lot.”
Positive effect of depression on graduate student teaching
Understanding of student issuesDepression can positively impact graduate students as instructors because they are more understanding or sympathetic to student struggles, including mental health issues.23 (10)Student 16: “[My depression] maybe makes me a little more empathetic with the undergraduates that I teach. And I know that since depression is a big deal for me, it may be as big deal for them. I’m able to empathize better and help people seek out the right resources if necessary, and also give them a leniency that they need if they can’t accomplish something in the time it’s due because of their illness.”Student 48: “I think it makes me more empathetic to the plights of undergraduate students, because I know that they also experience a lot of these [mental health] problems, and so I think it makes me more sympathetic to their problems.”

a Forty-three out of the 50 students who participated in the study had experience teaching undergraduates either as a TA or as an instructor of record. We only considered the responses from the TAs with teaching experiences when calculating the percent of students who reported each theme.

Despite the increasing concern about graduate student mental health among those in the scientific community ( Pain, 2018 ; “The Mental Health of PhD Researchers,” 2019; Puri, 2019 ), there is a lack of information about how specific aspects of science PhD programs affect students with depression. This is the first study to explicitly investigate which particular aspects of research and teaching affect depression among life sciences PhD students and how depression, in turn, affects graduate students’ experiences in research and teaching. Overall, graduate students highlighted factors related to teaching and research that both alleviated and exacerbated their symptoms of depression. Graduate students more commonly brought up ways that research negatively affected their depression, than ways that it positively affected their depression. Conversely, graduate students more commonly mentioned ways that teaching had a positive effect on their depression compared with a negative effect. The requirement and opportunity to teach differs among life sciences graduate programs ( Schussler et al. , 2015 ; Shortlidge and Eddy, 2018 ). As such, future research should investigate whether the amount of teaching one engages in during graduate school is related to levels of graduate student depression. Despite differences in how teaching and research affect student depression, this study unveiled factors that protect against or worsen depressive symptoms. Specifically, four overarching factors affecting graduate student depression emerged from the interviews: 1) Structure; 2) Positive and Negative Reinforcement; 3) Failure and Success; 4) Social Support and Isolation. We discuss here how each of these factors may positively and negatively affect graduate student depression.

One stark contrast between research and teaching is the amount of structure in each activity. That is, students expressed that research goals are often amorphous, that there are not concrete instructions for what needs to be accomplished, and that there is often no set schedule for when particular tasks need to be accomplished. Conversely, with teaching, graduate students often knew what the goals were (e.g., to help students learn), exactly what they needed to accomplish each week (e.g., what to grade, what to teach), and when and where they needed to show up to teach (e.g., a class meets at a particular time). Graduate students highlighted that a lack of structure, particularly in research, was detrimental for their depression. Their depression often made it difficult for them to feel motivated when there was not a concrete task to accomplish. Major depression can interfere with executive function and cognition, making goal setting and goal achievement particularly difficult ( Elliott, 1998 ; Watkins and Brown, 2002 ). In fact, research has documented that individuals with depression generate less specific goals and less specific explanations for approaching a goal than individuals who do not have depression ( Dickson and Moberly, 2013 ). As such, it may be particularly helpful for students with depression when an activity is structured, relieving the student from the need to articulate specific goals and steps to achieve goals. Students noted that the lack of structure or the flexibility in research was helpful for their depression in one way: It allowed them to better treat their depression. Specifically, students highlighted that they were able to take time to go to therapy or to not go into the lab or to avoid stressful tasks, which may be important for successful recovery from a depressive episode ( Judd et al. , 2000 ).

Compared with conducting research, many participants reported that the concrete tasks associated with teaching undergraduates were helpful for their depression. This is supported by literature that illustrates that concrete thinking, as opposed to abstract thinking, can reduce difficulty making decisions in individuals with depression ( Dey et al. , 2018 ), presuming that teaching often requires more concrete thinking compared with research, which can be more abstract. Additionally, cognitive-behavioral treatments for depression have demonstrated that developing concrete goals for completing tasks is helpful for individuals with depression ( Detweiler-Bedell and Whisman, 2005 ), which aligns with graduate students’ perceptions that having concrete goals for completing teaching tasks was particularly helpful for their depression.

Positive and Negative Reinforcement

Graduate students reported that the negative reinforcement experienced in research and teaching had a significant negative effect on their depression, while the positive reinforcement students experienced only in teaching had a positive effect. Notably, students did not mention how positive reinforcement affected their depression in the context of research. Based on student interviews, we predict that this is not because they were unaffected by positive reinforcement in research, but because they experienced it so infrequently. Drawing from behavioral theories of depression, the concept of response-contingent positive reinforcement (RCPR; Lewinsohn, 1974 ; Kanter et al. , 2004 ) helps explain this finding. As summarized by Kanter and colleagues (2004) , RCPR describes someone seeking a response and being positively reinforced; for example, graduate students seeking feedback on their research are told that what they have accomplished is impressive. Infrequent RCPR may lead to cognitive symptoms of depression, such as low self-esteem or guilt, resulting in somatic symptoms of depression, such as fatigue and dysphoria ( Lewinsohn, 1974 ; Martell et al. , 2001 ; Manos et al. , 2010 ). RCPR is determined by three factors. 1) How many potential events may be positively reinforcing to an individual. For example, some people may find an undergraduate scoring highly on an exam in a class they are teaching to be reinforcing and others may find that they only feel reinforced when an undergraduate explicitly compliments their teaching. 2) The availability of reinforcing events in the environment. If graduate students’ mentors have the ability to provide them with RCPR but are never able to meet with them, these reinforcing events are unavailable to them. 3) The instrumental behavior of an individual. Does the individual exhibit the behavior required to obtain RCPR? If graduate students do not accomplish their research-related tasks on time, they may not receive RCPR from their mentor. If individuals are not positively reinforced for a particular behavior, they may stop exhibiting it, further exacerbating the depressive cycle ( Manos et al. , 2010 ). Therefore, the lack of positive reinforcement in research may be particularly damaging to graduate students, because it may discourage them from completing tasks, leading to additional depressive symptoms. Conversely, teaching presents many opportunities for positive reinforcement. Every time graduate students teach, they have the opportunity to receive positive reinforcement from their students or to witness a student’s academic accomplishment, such as an undergraduate expressing excitement when they understand a concept. As such, it is not surprising that positive reinforcement was the primary teaching-related factor that graduate students reported helped with their depression. Despite the positive reinforcement of teaching for graduate students with depression, we are not suggesting that graduate students should take on additional teaching loads or that teaching should be viewed as the sole respite for graduate students with depression. Overwhelming students with increased responsibilities may counteract any positive impact that teaching could have on students’ depression.

Failure and Success

Failure and success affected student depression, but only in the context of research; contrary to research, students rarely mentioned concrete metrics for success and failure in teaching. While graduate students highlighted receiving positive or negative reinforcement from undergraduates, they did not relate this to being a “successful” instructor. It is unsurprising that graduate students did not mention failing or succeeding at teaching, given that experts in teaching agree that it is difficult to objectively evaluate quality teaching ( d’Apollonia and Abrami, 1997 ; Kember et al. , 2002 ; Gormally et al. , 2014 ). In fact, the lack of teacher training and knowledge about how to teach effectively negatively affected student depression, because it could cause students to feel unprepared as an instructor. Integrating teacher training into graduate programs has been championed for decades ( Torvi, 1994 ; Tanner and Allen, 2006 ; Schussler et al. , 2015 ); however, the potential for such training to bolster graduate student mental health is new and should be considered in future research. With regard to graduate students’ research, the concept of success and failure was far more concrete; students mentioned failing in terms of failed experiments, research projects, and rejected manuscripts and grant proposals. Successes included accepted manuscripts, funded grant proposals, and concrete progress on significant tasks, such as writing or conducting an experiment that yielded usable data. Failure has been shown to negatively affect depression among undergraduate researchers ( Cooper et al. , 2020a ), who are hypothesized to be inadequately prepared to experience failure in science ( Henry et al. , 2019 ). However, it is less clear how well prepared graduate students are to experience failure ( Simpson and Maltese, 2017 ). Drawing from cognitive theories of depression, depression is associated with dysfunctional cognitive schemas or dysfunctional thinking that can lead individuals with depression to have negative thoughts about the world, themselves, and the future and to interpret information more negatively than is actually the case (called negative information-processing biases; Beck, 1967 ; Beck et al. , 1979 ; Gotlib and Krasnoperova, 1998 ; Maj et al. , 2020 ). Related to failure, individuals with dysfunctional cognitive schemas may harbor beliefs such as if something fails at work (or in graduate research), they are a failure as a person or that a small failure can be as detrimental as a larger failure ( Weissman, 1979 ; Miranda and Persons, 1988 ). As such, setbacks in research may be particularly difficult for PhD students with depression. Graduate students in our study also mentioned how failing in research was often out of their control, particularly failure related to experiments and research projects. The extent to which one feels they can control their environment is important for mental health, and lower estimates of control have been hypothesized to be an important factor for depression ( Grahek et al. , 2019 ). Therefore, this feeling of being unable to control success in research may further exacerbate student depression, but this would need to be tested. Importantly, these findings do not imply that individuals with depression are unable to cope with failure; they only suggest that individuals perceive that failure in science can exacerbate their depression.

Social Support and Isolation

Graduate students reported that feelings of isolation in research could worsen their depression. Specifically, they highlighted that it can be difficult for their mental health when their friends outside graduate school cannot relate to their struggles in research and when others in their research group are not working on similar projects. One study of more than 1400 graduate students at a single university found that feeling isolated from fellow graduate students and faculty positively predicted imposter phenomenon ( Cohen and McConnell, 2019 ), defined as the worry that they were fooling others about their abilities and that their fraudulence would be exposed ( Clance and Imes, 1978 ), which is positively correlated with depression among college students ( McGregor et al. , 2008 ). Developing a positive lab environment, where undergraduates, graduate students, and postgraduates develop positive relationships, has been shown to positively affect undergraduates ( Cooper et al. , 2019 ) and may also positively affect graduate students who experience such feelings of isolation. Graduate students in this study described that both teaching and research had the potential to be a source for relationship development and social support. Students who described positive collaborative relationships in research and teaching felt this had a positive impact on their depression, which aligns with a review of studies in psychiatry concluding that being connected to a large number of people and having individuals who are able to provide emotional support by listening or giving advice is protective against depression ( Santini et al. , 2015 ), as well as a study that found that social support is protective against depression, specifically among the graduate population ( Charles et al. , 2021 ).

These four factors provide clear targets for graduate programs looking to improve the experiences of students with depression. For example, increasing structure in research could be particularly helpful for graduate students with depression. Ensuring that students have concrete plans to accomplish each week may not only positively impact depression by increasing structure, but ultimately by increasing a student’s success in research. Research mentors can also emphasize the role of failure in science, helping students realize that failure is more common than they may perceive. Increasing opportunities for positive reinforcement in teaching and research may be another avenue to improving student mental health. Providing students with appropriate teacher training is a first step to enhancing their teaching skills and potential for positive reinforcement from undergraduate students ( Schussler et al. , 2015 ). Additionally, teaching evaluations, a common form of both positive and negative reinforcement, are known to be biased and disadvantage women, People of Color, and those with non–English speaking backgrounds ( Fan et al. , 2019 ; Chávez and Mitchell, 2020 ) and arguably should not be used to assess teaching. In research, mentors can make an effort to provide positive feedback or praise in meetings in addition to critiques. Finally, to provide social support to graduate students with depression, graduate programs could consider creating specific initiatives that are related to supporting the mental health of graduate students in their departments, such as a support group for students to meet and discuss their experiences in graduate school and how those experience pertain to their mental health.

Limitations and Directions for Future Research

In this study, we chose to only interview students with the identity of interest (depression), as is common with exploratory studies of individuals with underserved, underrepresented, or marginalized identities (e.g. Carlone and Johnson, 2007 ; Cooper and Brownell, 2016 ; Barnes et al. , 2017 , 2021 ; Downing et al. , 2020 ; Gin et al. , 2021 ; Pfeifer et al. , 2021 ). However, in future studies, it would be beneficial to also examine the experiences of individuals who do not have depression. This would provide information about the extent to which specific aspects of graduate research and teaching are disproportionately beneficial or challenging for students with depression. In this study, we did not explicitly examine whether there was a relationship between students’ identities and depression because of the small number of students in particular demographic groups. However, a theme that occurred rather infrequently (but is included in the Supplemental Material) is that discrimination or prejudice in the lab or academia could affect depression, which was reported exclusively by women and People of Color. As such, disaggregating whether gender and race/ethnicity predicts unique factors that exacerbate student depression is an important next step in understanding how to create more equitable and inclusive research and teaching environments for graduate students. Moreover, our sample included a significant number of students from ecology and evolutionary biology PhD programs, which may limit the generalizability of some findings. It is important to acknowledge potential subdisciplinary differences when considering how research may affect depression. Additionally, some of the factors that affect student depression, such as lack of teaching training and confidence in teaching, may be correlated with time spent in a graduate program. Future quantitative studies would benefit from examining whether the factors that affect student depression depend on the student’s subdiscipline and time spent in the graduate program. The primary focus of this study was the relationship between depression and graduate teaching/research. Many of the factors that emerged from the interviews are also associated with burnout ( Bianchi et al. , 2014 ; Maslach et al. , 2001 ). Burnout and depression are known to be highly related and often difficult to disaggregate ( Bianchi et al. , 2014 ). It was beyond the scope and design of this study to disaggregate which factors relate exclusively to the condition of burnout. Additionally, the interviews in this study were collected at a single time point. Thus, we are unable to differentiate between students who had depression before starting graduate school and students who experienced depression after starting graduate school. Future longitudinal studies could explore the effects of students’ experiences in research and teaching on their depression over time as well as on long-term outcomes such as persistence in graduate programs, length of time for degree completion, and career trajectory. This study identified a number of factors that graduate programs can address to benefit graduate student mental health, and we hope that future studies design and test interventions designed to improve the experiences of graduate students in teaching and research.

In this interview study of 50 life sciences PhD students with depression, we examined how graduate research and teaching affect students’ depressive symptoms. We also explored how depression affected graduate students’ teaching and research. We found that graduate students more commonly highlighted ways that research negatively affected their depression and ways that teaching positively affected their depression. Four overarching factors, three of which were related to both teaching and research, were commonly associated with student depression, including the amount of structure provided in research and teaching, failure and success, positive and negative reinforcement, and social connections and isolation. Additionally, graduate students identified depression as having an exclusively negative effect on their research, often hindering motivation, concentration, and self-esteem. However, they did note that depression made them more compassionate teachers, but also could cause them to have low energy or feel disconnected when teaching. This study provides concrete factors that graduate programs can target in hopes of improving the experiences of life sciences PhD students with depression.

Important Note

There are resources available if you or someone you know is experiencing depression and want help. Colleges and universities often have crisis hotlines and counseling services designed to provide students, staff, and faculty with treatment for depression. These can often be found by searching the university website. Additionally, there are free 24/7 services such as Crisis Text Line, which allows you to text a trained live crisis counselor (text “CONNECT” to 741741; Text Depression Hotline, 2019 ), and phone hotlines such as the National Suicide Prevention Lifeline at 1-800-273-8255 (TALK). If you would like to learn more about depression or depression help and resources near you, visit the Anxiety and Depression Association of American website: https://adaa.org ( Anxiety and Depression Association of America, 2019 ) and the Depression and Bipolar Support Alliance: http://dbsalliance.org ( Depression and Bipolar Support Alliance, 2019 ).

Acknowledgments

We are incredibly grateful to the 50 graduate students who were willing to share their personal experiences with us. We thank Sara Brownell, Tasneem Mohammed, Carly Busch, Maddie Ostwald, Lauren Neel, and Rachel Scott for their helpful feedback on earlier drafts of this work. L.E.G. was supported by an NSF Graduate Fellowship (DGE-1311230). Any opinions, findings, conclusions, or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the NSF.

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Must depression be irrational?

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  • Published: 21 August 2024
  • Volume 204 , article number  79 , ( 2024 )

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thesis statement in depression

  • Dan Cavedon-Taylor   ORCID: orcid.org/0000-0003-4474-1700 1  

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The received view about depression in the philosophical literature is that it is defined, in part, by epistemic irrationality. This status is undeserved. The received view does not fully reflect current clinical thinking and is motivated by an overly simplistic, if not false, account of depression’s phenomenal character. Equally attractive, if not more so, is a view that says depression can be instantiated either rationally or irrationally. This rival view faces challenges of its own: it appears to entail that there are situations when not being depressed is rationally sub-optimal and that resilience to, and healthy coping strategies for avoiding, depression can be rationally remiss. I criticise an existing reply to these challenges before motivating a better one from the perspective of epistemic consequentialism.

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1 Introduction

Harry has struggled to get out of bed for the past two weeks. Today, he clothes and feeds his two children and drives them to school. But he does so irritably, with great impatience. When the children inevitably drag their heels, quarrel, etc. he shouts at them, loudly and disparagingly. Back at home, he collapses in bed, exhausted, and feels enormous guilt for how he has acted. None of this is unusual. Recently, Harry has found himself feeling empty most days. Today, he is meant to go to the store to buy food for the week. He knows that this won’t happen. Also, the kids’ clothes need washing and the kitchen needs cleaning too. Then there are those bills. It is incomprehensible to Harry that he can see to these things.

Jan has found it difficult to get out of bed for the past two weeks too. She too feels empty and fatigued. She usually spends her commute busying away on her phone, catching up with friends and family on social media. Today, Jan can’t bring herself to look at the screen. The notifications mount up and it suddenly feels an overwhelming burden. In a meeting after lunch, a colleague makes a mildly dismissive remark about an idea of Jan’s and she nearly bursts into tears. Jan doesn’t think that she will go into work tomorrow and starts formulating excuses that she will later tell her boss. As with Harry, none of these are isolated incidents.

Harry and Jan are depressed. In this, they are not alone. In the United States, 2-3% of men and 5-9% of women suffer from depression, with the probability of developing the condition 5-12% and 10-25% for each group, respectively (Beck & Alford, 2009 , p.4). Globally, more than 280 million people are estimated by the World Health Organisation to suffer from depression (WHO, 2023 ).

The issue I address here is the extent to which it is essential to depression that it involves an epistemically irrational response to life events.

Why might one think such a thing? Suppose that Harry is diagnosed with Major Depressive Disorder with a Seasonal Pattern and that Jan is diagnosed with Perinatal Depression. A change in season has caused Harry to be depressed. But that doesn’t give him a reason to be depressed. And Jan, we may suppose, has desperately wanted to become pregnant and start a family with her loving husband. Becoming pregnant has caused Jan to be depressed. But given her life plans, Jan instead has reason to feel joy, with slight trepidation perhaps. Like Harry’s depression, Jan’s is also ‘out of sync’ with the facts as she apprehends them. Moreover, depression aside, psychological disorders are often conceptualised, from philosophical and lay perspectives, as entailing failures of epistemic rationality (see Bortolotti, 2013 for an overview). As Arpaly ( 2005 , p.284) puts it, “being told that one has a mental disorder is first and foremost being told that one has unwarranted mental states.”

So reflection on people like Harry and Jan, and psychological disorder more generally, may motivate the following view:

The Irrationality View of Depression : Necessarily, depression is an irrational response to the (apparent) events in one’s life.

The Irrationality View says it is a conceptual truth that depression is without justification in adverse life events. Here are some statements of support in the philosophical literature:

[D]epression crucially involves states that are unwarranted by or disproportionate to events in the subject’s life… [N]ecessarily, if S has depression, then the states and events comprising S’s depressive symptoms are not an appropriate or proportionate response to antecedent events in her environment. (Davies, 2016 , p.293) [D]isproportion to circumstances and thus lack of [rational] explanation in terms of circumstances is an essential aspect of depressive disorder. (Wakefield & Demazeux, 2016 , p.4) [S]ymptoms that have some sufficient justification – for example, the loss of one’s job – and, crucially, that are a proportional response… are not indicative of [depression]. Conversely, those symptoms which do not have sufficient justification (e.g., those which arise ‘out of the blue’)… are indicative of [depression]. (Tully, 2019 , p.116)

The Irrationality View might be sloganized as the claim that causes of depression never justify depression. Its defenders sometimes draw a contrast here between depression, qua psychological disorder, and grief, qua normal (or healthy) psychological episode. For although feelings of grief may spiral into illness and become pathological, they appear a reasonable response to the irreversible loss of something or someone of value (Cholbi, 2017 ). Footnote 1

Yet the Irrationality View is not without drawbacks. For one, the view entails that severe sexual or physical assault, loss of home and livelihood and refugee experience never justify being depressed. For some of us, this seems plainly incorrect. As Bortolotti ( 2013 , p.483) suggests, “Some forms of anxiety and depression may seem reasonable responses to life events.” Graham ( 1990 , p.408) agrees, claiming, in contrast to the Irrationality View, that “people sometimes suffer in circumstances so bad or terrible that it is beyond belief that they are not justified for depression.” Recently, Kate Abramson has offered gaslighting as circumstances that may reasonably cause one to be depressed. Abramson ( 2024 , p.152) claims it is “outrageous” to say of someone who suffers depression as a result of gaslighting that they have ipso facto failed rationally. Rather, being depressed in such circumstances is, she claims, a “fitting evaluative response” (p.154).

So granted, it might be true of some depressed individuals, like Harry and Jan, that the cause of their depression does not also rationalise their depression. But that this is true of all instances of depression, and true of all depressed individuals, is not so obvious. If that is right, then a possibility worthy of serious consideration is that the Irrationality View is false. Instead, depression is justified on some occasions and other times not. For instance, in line with the claims of Bortolotti, Graham and Abramson, it might be that depression caused by, say, refugee experience, homelessness, gaslighting and other serious trauma is justified, whereas depression caused by change of season is not. And perhaps depression as a result of, say, pregnancy can be justified or unjustified depending on one’s life circumstances, how one has become pregnant, one’s prior desire to (not) have a child, one’s wider support network, and so on. Footnote 2

Moreover, just as the situations in which one can be depressed are varied, so too is depression itself. Harry’s and Jan’s depressions are individuated by their causes: Harry has Major Depressive Disorder with a Seasonal Pattern and Jan has Perinatal Depression. By contrast, Psychotic Depression is depression that is individuated by its concomitants, e.g., delusions and hallucinations, rather than its cause. Different yet again is Dysthymia, a form of depression that is individuated both by its mild nature and the prolonged length of its episodes. Where depression is so heterogenous, it would be surprising if its relation to epistemic rationality were entirely homogenous (see also Arpaly, 2005 , pp.287–288).

So where can one turn to find unequivocal opposition to the Irrationality View? Pockets of resistance exist, as evidenced above, but one must look hard to find them. Footnote 3 I aim to level the playing field, showing a number of flaws in the Irrationality View and defending the following view instead:

The Mixed View of Depression : Depression can be a rational or irrational response to the (apparent) events in one’s life.

Whereas the Irrationality View says that instantiations of depression are necessarily unjustified and hence irrational, the Mixed View says that depression can be instantiated either unjustifiably or justifiably. The Mixed View makes depression rationally continuous with various other mental states, e.g., beliefs, emotions, etc. insofar as these are also sometimes epistemically rational or otherwise well-supported, and other times not. In making a case that depression is sometimes rational, I join the ranks of several other authors who have recently argued that some psychological disorders are not intrinsically irrational and that their episodes are sometimes epistemically befitting one’s situation. This includes conditions as diverse as post-traumatic stress disorder (McSweeney, 2023 ), obsessive compulsive disorder (Haerle, 2023 ) and various eating disorders (Gadsby, 2023 ).

Here is the plan. In the next section, I clarify the nature of the disagreement between the Irrationality View and the Mixed View. In Sects.  3 and 4 , I go on the offensive, arguing that the Irrationality View receives mixed support at best from current psychiatric thinking while also assuming an overly simplistic account of depression’s phenomenal character. In Sects.  5 and 6 , I go on the defensive, supporting the Mixed View against two potential objections, and which might motivate a reductio of the view; I’ll assess, and find wanting, an existing defence of the Mixed View against these, due to Graham ( 1990 ), before motivating an alternative one via a broadly consequentialist approach to epistemic rationality.

Before beginning I want to be clear about my aims. Rather than proving the Mixed View true and the Irrationality View false, I will be satisfied to have pointed out some drawbacks of the Mixed View and to have defended the Irrationality View against objections. Thus, my aim is to even the odds between the views.

2 The irrationality view and the mixed view: clarifying the issues

To say that depression is epistemically irrational is to say that it fails to be reason-responsive. But psychological states can fail to be reason-responsive in at least two ways. First, a psychological state might fail to be reason-responsive in its aetiology . That is, a state may be epistemically irrational at its point of instantiation, having been formed in such a way that didn’t take into account of, or perhaps even went against, relevant evidence. Second, a psychological state may fail to be reason-responsive insofar as, once instantiated, it is impervious to reasoning. That is, once in place, the state can’t be modified by countervailing considerations. That is, a psychological state may be epistemically irrational in terms of its being maintained in the face of psychological defeaters. I shall call these different forms of irrationality aetiological irrationality (irrationality in causal history) and maintenance irrationality (irrationality in how an already instantiated state is sustained). Footnote 4

The Irrationality View says that, necessarily, depression is epistemically irrational in that it is disproportionate to one’s (apparent) life events. Footnote 5 Strictly speaking, this claim is ambiguous between the claim that depression involves aetiological irrationality and the claim that it involves maintenance irrationality (or both). However, examining the above remarks by defenders of the view suggests it is aetiological irrationality that characterises the Irrationality View. In the above quotes, the view’s defenders talk about depression being irrational at its point of instantiation, i.e. its necessarily being an inappropriate response to “antecedent events” in the person’s life (Davies, 2016 , p.293), arising “out of the blue” (Tully, 2019 , p.116) and lacking in any form of circumstantial “explanation” (Wakefield & Demazeux, 2016 , p.4). These are claims about how episodes of depression are triggered, never mind how they continue to persist (or go out of existence). This is not to say that there are no interesting issues to examine in terms of depression’s relation to maintenance rationality. There certainly are. Insofar as depression characteristically involves not just low mood, but a loss of mood reactivity, the condition may, ipso facto , be pictured as involving maintenance irrationality. But as there are these two different dimensions to epistemic rationality, a psychological state may be epistemically rational along one such dimension but epistemically irrational along the other. For instance, a belief may be formed on good evidence, and so exhibit aetiological rationality, but then come to be sustained in the face of opposing evidence, and so be irrational in how it is maintained.

To be clear, then: the lens of epistemic rationality through which I am examining the debate between the Irrationality View and the Mixed View is aetiological irrationality, where this is a matter of a psychological state’s being either well- or ill-supported when first instantiated, independent of whether or not it continues to be well- or ill-supported by consequent events in a person’s life.

These two senses of epistemic rationality are often run together. But they should be distinguished. Here is a putative example that underscores how they might come apart in the case of depression: Harry’s depression might be said to be aetiologically irrational, since it is caused by mere change of season, and yet his depression might eventually become rational, depending upon the subsequent events in his life, say, he loses his job, is rendered homeless or suffers other forms of trauma. Converse cases, where aetiologically rational depression becomes maintained in an irrational way are also possible. For instance, depression as a result of severe assault may be aetiologically rational and yet end up being maintained in an irrational way due to the person’s developing paranoid, persecutory delusions. Footnote 6 Of course, the extent to which one finds these examples plausible depends on one’s being antecedently sympathetic to the Mixed View.

The question of whether depression must be aetiologically irrational is orthogonal to the question of whether depression is an adaptation. The question of a mental disorder’s adaptiveness can be disambiguated in several ways. Plutynski ( 2023 ) has recently identified four: namely, a condition’s (i) having served some function in the evolutionary past and continuing to perform that function; (ii) having served some function in the evolutionary past, but no longer performing that function; (iii) having served some function at one stage of a person’s life, while no longer serving that function now and possibly even being maladaptive in the long run; and (iv) serving some function currently, but overall being less than optimal.

In the case of depression, psychiatrist Nesse ( 2000 ) has given perhaps the most well-known defence of the claim that the condition is an adaptation. Nesse claims that depression developed in circumstances where it was beneficial for our ancestors to cease futile or dangerous activities, but where it likewise benefitted them to temporarily withdraw from all undertakings rather than immediately commence new ones. On Nesse’s view, depression is a mechanism we developed to prevent us from jumping out of the frying pan and into the fire.

Nesse’s account says depression an adaptation, but, as Plutynski suggests, only in sense (ii). That is because accounts like Nesse’s are concerned with how there came to be the type of state that we call ‘depression’; they don’t speak to the question of whether and when tokens of such a state instantiated now might be epistemically rational in their aetiology. Strictly speaking, such accounts leave open whether all instantiations of depression are irrational. For instance, in the face of a theory like Nesse’s, about how depression arose in our ancestral past, defenders of the Mixed View may still motivate their position by pointing to the intuitive contrast between depression as a result of change of season (putatively ill-supported and hence irrational in aetiology) and depression as a result of serious trauma (putatively well-supported and hence rational in aetiology). Defenders of the Mixed View may rightly argue that this contrast goes unexplained by adaptive theories such as Nesse’s.

Another issue is whether the disagreement between the Irrationality View and the Mixed View is merely verbal. Consider Jan, and suppose that she does not have Perinatal Depression, but was instead the victim of a prolonged and aggravated assault. On the assumption that low mood and depleted motivation are now (sadly) an appropriate and proportionate response to Jan’s life-events, the Irrationality View is likely to require that we rescind the claim that Jan is depressed. (Recall the quotes above.) By contrast, defenders of the Mixed View will likely be open to the possibility that Jan is depressed. Yet both views agree on the substantive psychological facts; namely, that:

Jan is distressed (is experiencing low mood, depleted motivation, a desire to socially withdraw, etc.);

Jan’s being distressed is aetiologically rational, given the assault; and.

The nature of that distress (low mood, depleted motivation, a desire to socially withdraw, etc.) is common to both Jan’s current condition and depression proper.

What the Irrationality View and the Mixed View disagree on is whether the following is true:

Jan is depressed.

But with so much agreement between the views, especially on (c), one might think that disagreement over (d) is merely verbal and that nothing can be gained from pitting the two views against one another.

This is very much mistaken. As Davies ( 2016 ) points out in his defence of the Irrationality View, the latter is an instance of what he calls ‘psychiatric externalism.’ Psychiatric externalism says that mental disorder does not supervene on psychological features of a person alone, but is partially a matter of what relations they bear to the environment: in the case of depression, whether the person’s low mood, motivational depletion, desire to socially withdraw, etc. is a disproportionate response to antecedent life events. Crucially, the Irrationality View entails that two persons can be psychological duplicates, both with low mood, lack of motivation, desire to socially withdraw, etc. yet one be depressed and the other not, depending on whether these psychological states have insufficient grounding in life events or not. Davies writes:

Given a suitably dystopian context, devoid of any reason to be happy, even the severest of depressed mood might not qualify as pathological. The facts that determine whether or not an individual is depressed therefore must include facts about her environment. (p.293)

The Irrationality View is thus a substantial metaphysical thesis about the conditions under which depression is instantiated, just as traditional externalism in philosophy of mind is a substantial metaphysical thesis concerning the conditions under which psychological contents are instantiated (Putnam, 1975 ; Burge, 1979 ). So then the Mixed View, which denies the Irrationality View, must be a substantial metaphysical thesis too, and debate between them must likewise be considered at least somewhat weighty and not merely verbal. Indeed, one way to mark the difference between the Irrationality View and the Mixed View is to note that the latter is more internalist in nature. By claiming that depression can be both aetiologically rational or irrational, the Mixed View holds that factors about how one’s state(s) of mind happen to be caused are unimportant for whether one is depressed or not. It is worth emphasising: this claim is consistent with various depressions themselves being individuated by causal history. What makes someone depressed per se may be their psychological states alone (never mind the causes) but what makes the depression one kind rather than another (e.g., perinatal vs. delusional) can be a matter of relations to the environment. Compare: what makes something count as water is its intrinsic chemical composition—the presence of H 2 O. Yet what makes something count as spring water, and not tap water, is determined by recent causal history. So the Mixed View can accommodate the idea that some depressions are individuated by their causes while depression per se is determined acausally, i.e. by intrinsic psychology alone.

But what is depression? The 5th and most recent edition of The American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders ( 2013 , pp.160–161) says that someone is depressed if they present with either (i) low mood or (ii) diminished interest in, or pleasure derived from activities (anhedonia), in addition to having four or more of the following symptoms over a two-week period:

Weight loss or decrease/increase in appetite;

Insomnia or hypersomnia;

Psychomotor agitation or retardation;

Feelings of worthlessness or excessive or inappropriate guilt;

Diminished concentration; and.

Thoughts of death/suicide.

Some of these, particularly (iii) – (vi) do not seem legitimate targets for rational appraisal. Does this stop the Mixed View in its tracks? If it does, then it stops the Irrationality View from getting off the ground too, since criteria like (iii) – (vi) are not necessarily irrational. But arguably the DSM does not define mental health conditions. In the main, the DSM is a diagnostic tool. It outlines for clinicians criteria for attributing mental health conditions to patients. Some of its criteria can therefore be considered epistemic in nature; that is, as drawing the clinician’s attention to tell-tale signs of a condition, rather than specifying criteria metaphysically constitutive of disorder (see also Bueter, 2019 , p.1067).

What, then, are the options for theories of depression? Graham ( 1990 , pp.401–403) claims that depression is a combination of certain beliefs, emotions and desires. Ratcliffe ( 2014 ) identifies depression with a single state, a ‘existential feeling’ that, roughly, disrupts one’s sense of the world as allowing for possible actions. Tully ( 2017 ) claims that severe depression involves a complete lack of desires. Whiteley (forthcoming) claims that depression is an ‘altered’ or ‘global’ state of consciousness akin to dreaming. This is a paper about the rationality of depression and not its fundamental nature. That is a matter on which I aim to remain as neutral as possible throughout. Indeed, I am tempted to think that the fundamental nature of depression can only be settled once we agree upon answers to questions like ‘can depression ever be rational?’ We can all agree: depression typically involves low mood, lack of motivation, a desire to socially withdraw, negative self-directed beliefs, feelings of guilt and hopelessness, etc. Footnote 7 But is that what depression is, in and of itself? Or are these depression’s effects? Could they be mere concomitants? Might they instead be depression’s causes? Knowing whether instantiations of depression are always irrational, or whether they can sometimes be rational, may help us decide between options here, both in terms of answering these particular questions and deciding between theories of depression’s nature more generally.

Granted, insofar as the Mixed View is at odds with externalism about depression it does have some metaphysical commitments, namely about the circumstances under which states of depression become instantiated. But this still leaves it open what particular state, or collection of states, depression is to be identified with. This is what I will not offer any positive remarks on. Footnote 8 Moreover, the Mixed View has a significant commitment insofar as it entails that whatever kind of state (or collection of states) depression is to be identified with, that state (or collection of states) has a rationally appraisable aetiology. But in this respect, the Mixed View agrees with the Irrationality View. It is just that the two views disagree on matters of valence.

Some might prefer a view on which depression’s aetiology is, like that of perceptual experiences or pains, fully arational; that is, not the kind of thing one can rationally appraise in the first place. For instance, one may prefer a view like the following:

The Arationality View of Depression : Depression is an arational response to the (apparent) events in one’s life.

On this view, it doesn’t make sense to enquire into the rationality of instantiations of depression. Footnote 9 That would be to disagree with both the Irrationality View and the Mixed View. Since my focus here is on which of the latter two views to prefer, I leave substantive discussion of arational accounts of depression for another time. Footnote 10 But it is worth mentioning an issue that might lead one to reject the debate between the Irrational and Mixed views as misguided and motivate supporting the Arationality View instead; namely, the fact that people don’t become depressed at will.

The fact that depression is not under one’s direct control or instantiated voluntarily should not be taken as decisive against the Mixed View (nor the Irrationality View). Arguably, beliefs cannot be formed at will, yet clearly beliefs can be justified or unjustified. Indeed, as Graham notes, in his discussion of the rationality of depression, there are a great many things that occur in the mind that we do not have direct control over, but which we take to be rationally appraisable:

Exam mistakes, offensive moral views are all nonvoluntary, but we don’t hesitate criticizing people for them, or judging them as unreasonable mistakes, unjustified views. The mere fact that depression is not directly voluntary does not mean it cannot be justified. ( 1990 , p.410)

I offer two final remarks on my approach and the dialectic between the Irrationality View and the Mixed View.

First, I remain neutral on the precise nature of aetiological rationality, observing that this is, in some further sense to be explained, a matter concerning a mental state’s causal history (or counterfactual dependence on prior facts) serving as normative support for that mental state (see Sylvan, 2016 ; Korcz, 2021 for options). This is a matter for defenders of both the Irrationality View and Mixed View to say more on, but I leave that for another time.

Second, defenders of the Mixed View may or may not agree with defenders of the Irrationality View that depression is necessarily pathological, a matter for medical intervention, or something that needs to be ‘treated’ another way. The view leaves all this open. The Mixed View may give the appearance of saying that depression, when rational, is a condition it is imprudent to seek relief from. But that is incorrect. Compare: people are not imprudent to seek relief from, say, justified anger, if it harms them (e.g., raises their blood pressure). And just as many different forms of treatment are available for high-blood pressure, some physician-prescribed and monitored and some not (e.g., yoga and exercise), the same is true of depression. The Mixed View leaves open how people with depression should be treated, but it certainly does not proscribe against treatment.

In the next two Sects. (3 and 4) I attempt to undercut motivations for the Irrationality View before moving onto a defence of the Mixed View (5 and 6).

3 Against the irrationality view I: the current clinical zeitgeist

In his defence of the Irrationality View, Davies ( 2016 , p.293) speculates that it reflects “the current clinical zeitgeist.” In this section, I shall raise various doubts about that claim. In doing so, my aim is to undermine a potentially key motivation for the Irrationality View; namely, that it is supported by current clinical thinking about depression. In response, I will not claim that current psychiatry gives no support for the Irrationality View. But it does seem to me that current psychiatry gives ambivalent support for that view, at best.

3.1 The DSM

In Sect.  2 , I outlined the DSM-5 criteria for depression. Put aside the question of whether that criteria is wholly epistemic in nature or whether some of it is metaphysically constitutive of depression. What I wish to draw attention do is this: the DSM gives no indication of it mattering to someone’s being depressed how symptoms meeting criteria (i) – (ix) are caused. By contrast, the driving thought behind the Irrationality View is that depression should not be judged present “without considering the nature of [the] trigger” (Wakefield et al., 2007 , p.434). But insofar as the DSM-5 omits to mention the need for such an investigation when diagnosing depression, it is in conflict with the Irrationality View.

Naturally, this is a matter of dissatisfaction to defenders of the Irrationality View. For instance Jerome Wakefield, a chief defender of that view, has advocated that the DSM should include an overall ‘disproportionality to circumstance’ criterion that symptoms have to meet to be considered indicative of depression. Wakefield has repeatedly cautioned that, without such a criterion, psychiatry risks misdiagnosing ‘normal’ sadness, non-pathological grief in particular, as psychological disorder (Horwitz & Wakefield, 2007 ; Wakefield et al., 2007 ; Wakefield & Horwitz, 2016 ). I will have some things to say in the following section about the idea that extrinsic, aetiological facts alone can distinguish depression from grief; namely, that it is false. The point I am developing at present is that the Irrationality View is not as firmly reflected in current mainstream clinical thinking about depression as some of its defenders imply.

Granted, previous editions of the DSM were more consistent with the Irrationality View. They incorporated a bereavement exclusion: the DSM-III and DSM-IV stated that someone does not have depression if, despite having criteria-meeting symptoms, these can be explained by the recent death of a loved one. This did make extrinsic factors relevant to depression’s diagnosis. So was the Irrationality View, from the perspective of the DSM, at least previously a part of the ‘clinical zeitgeist?’ Not obviously. For there was no wider exclusion, covering other traumatic events like sexual or physical assault, homelessness, gaslighting, refugee experience, and so on. Despite appearances, these previous editions of the DSM were only partially consonant with the Irrationality View.

Indeed, as some clinicians rightly observed, the presence in earlier DSMs of a bereavement exclusion, but not an exclusion for other traumatic events was “not logically defensible” (Moran, 2011 , n.p.). When updating depression’s criteria in the DSM-5 and resolving this tension, psychiatry could have taken one of two paths. It could have dropped the bereavement exclusion, abandoning any extrinsic, ‘disproportionality’ criteria as relevant for depression. Alternatively, the bereavement exclusion could have been extended to all adverse and traumatic life events; then, symptoms alone would never be sufficient for diagnosing depression. Instead, how those symptoms are caused—whether or not they are disproportionate responses—would have to be investigated before determining whether depression is present in a patient. If the history of psychiatry had gone down this second path, then the Irrationality View would reflect the current clinical zeitgeist. But as the above outline of the DSM-5’s depression criteria illustrates, The American Psychiatric Association did no such thing. They went with the first option: the DSM-5’s depression criteria entail that clinicians can determine depression’s instantiation on the basis of intrinsic, symptom-based features alone and ignore aetiological facts. Moreover, The American Psychiatric Association were motivated to go down this route on the grounds that the alternative, i.e. broadening the proportionality-based exclusion criteria, would be against the clinical status quo . A statement by a lead member of the DSM-5’s mood-disorder work group was emphatic about this. It claimed that additional proportionality exclusions would “represent a major shift, unsupported by a range of scientific evidence, in the nature of our concept of depression, as epidemiologic studies show that the majority of individuals develop major depression in the setting of psychosocial adversity” (reported in Moran, 2011 , n.p.).

Granted, the DSM-II of 1968 stated that depression involves an “excessive” reaction to life events. This claim is very much in line with the Irrationality View. But if the best that a defender of the Irrationality View who wants to establish the psychiatric pedigree of their view can do is show that their theory is reflected in one of five editions of the DSM (and from over 50 years ago) then this can hardly be considered a victory. To be clear: none of this is to say that the DSM is beyond reproach. The point is simply that insofar as the DSM may be thought to represent ‘the current clinical zeitgeist’, the characterisation of depression in the DSM-II, and which seems most friendly to the Irrationality View, is a historical outlier.

3.2 Situational depression

This brings us to a second respect in which current psychiatry’s resistance to the Irrationality View is evident. The kind of depression identified above by the DSM-5’s mood-disorder work group as potentially overlooked, should it recommend an Irrationality View-friendly extension of the bereavement exclusion to other adverse life events, is so-called ‘situational’ or ‘reactive’ depression. This form of depression contrasts with depression caused solely by genetic or biological factors, also known as ‘nonsituational’ or ‘nonreactive’ depression.

Nonsituational forms of depression arise, from the patient’s point of view, out of the blue, as Harry’s and Jan’s did, bearing no obvious epistemic relation to life events; hence their seemingly irrational nature. It is this kind of depression that the Irrationality View seems to unwittingly consider paradigmatic, if not exhaustive of depression. But situational forms of depression are highlight prevalent. Consider the following remarks by psychiatrist William Coryell and his colleagues ( 1994 ):

Studies of bereavement, of response to natural disasters and economic depression, and of associations between medical diseases and depressive illness, all point to the existence of situational and reactive depressions. (pp.203-4) Most clinicians are familiar with the depressed patient whose symptoms appear to be chronically intertwined with situational difficulties and adverse life events. (p.209)

This certainly sounds like a denial of the Irrationality View’s claim that, necessarily, depression must be without rationalisation and so must be aetiologically irrational in nature.

In reply, I anticipate that defenders of the Irrationality View will claim that they do, in fact, allow for situational forms of depression; such depression may be pictured, on their view, as a matter of one’s initial reaction to adverse life events spiralling out of control, with the symptoms taking on “a life of their own” (Horwitz & Wakefield, 2007 , p.18). As Davies writes in his defence of the Irrationality View:

Depression can be (and often is) precipitated by events that would reasonably be classed as saddening or tragic. The point is that the subject’s response may become pathological if its severity or duration exceeds some contextually determined threshold for appropriateness or proportionality to these events. ( 2016 , p.293; see also Tully, 2019 , p.116)

But when Coryell and their colleagues characterise adverse life events as “chronically intertwined” with depression, they do not seem to be thinking about situational forms of depression in this way. That is, they do not seem to consider adverse life events as distal triggers of such depression—as if challenging life events first cause a psychological state that is proportionate and which only later, through some dysfunction in the patient, turns excessive and transforms into depression. Instead, by saying that depression can be “chronically intertwined” with challenging life events, Coryell and colleagues seem to be saying that situational depression can be fully explained by such events and that the latter aren’t mere distal causes of the former. (They are also saying that most clinicians are familiar with cases like this.)

Furthermore, it has been argued in the psychiatric literature that the situational/nonsituational distinction might be scrapped entirely (Hirschfeld, 1981 ; Garvey et al., 1984 ; Kendler et al., 2010 ). For instance Kenneth Kendler and his colleagues ( 2010 , p.778) are unequivocal in claiming that depression is “best diagnosed in a context-independent manner.” This, again, is at odds with the Irrationality View, though quite consonant with the DSM-5 and the view of depression encapsulated by the Mixed View.

A defender of the Irrationality View might support their view as follows: because psychiatrists enquire into a patient’s life events prior to, or around the time of, symptom onset, aetiological facts are important for the condition’s diagnosis. But defenders of the Irrationality View pursuing this reply must rule out that the clinician’s interest in depression’s aetiology is not its relevance for other matters, such as determining treatment choice. For instance, the type of therapy most effective for a patient is known to vary depending upon the context in which their symptoms arose (Maj, 2012 ).

In sum, the clinician’s deck seems at best a mixed bag, relative to the Irrationality View. One cannot assume that Irrationality View is particularly well supported by current psychiatric thinking. I now intensify the case against the Irrationality View further; namely, by arguing that the master argument for the view rests on an overly simplistic account of depression’s phenomenal character.

4 Against the irrationality view II: is depression just Irrational Sadness?

Defenders of the Irrationality View claim that one must appeal to extrinsic factors to individuate depression, where this means facts about how its symptoms are caused. More precisely, the Irrationality View’s defenders appeal to the (putative) aetiological irrationality of the patient’s symptoms as the marker of depression. In doing so, they imply that depression and ‘normal’ or ‘healthy’ distressing states are intrinsically or psychologically alike, and so cannot be told apart independent of aetiology. For instance, consider the title of Horwitz and Wakefield’s ( 2007 ) polemic against the DSM: The Loss of Sadness: How Psychiatry Transformed Normal Sorrow into Depressive Disorder . Davies ( 2016 , p.293) similarly claims that a key reason for defending the Irrationality View is that divorcing depressive symptoms from their aetiology would leave one unable to “distinguish pathological depression from normal sadness.” Tully ( 2019 , p.115) makes the same claim in their defence of the Irrationality View. Often, grief is proposed as the relevant contrast. Indeed, this is something of a ‘master argument’ for the Irrationality View: aetiological facts are necessary to distinguish depression (which is an abnormal and harmful response to life’s events) from similar distressing states like grief (which is, by contrast, normal and healthy). Footnote 11

Notice how the view’s defenders imply with such remarks that depression has no distinguishing intentional-cum-phenomenal features. For if it did, then appealing to aetiological facts would be unnecessary to individuate the condition; we would be able to distinguish depression from normal sadness, like grief, by first-person features alone.

However, depression and grief can be distinguished on first-person grounds alone. This makes appeal to aetiological factors unmotivated and so undercuts this master argument for the Irrationality View. Once again, the psychiatric literature seems to go against the Irrationality View here. We will focus on depression first.

Consider the following account of the first-person features of depression from Desmond Curran and Erich Guttmann’s ( 1945 ) Psychological Medicine :

The typical affect is that of sadness, but has been described as being qualitatively… different to that normally experienced… [T]he patient feels changes—strange, lifeless, detached, automatic. Sometimes, instead of feeling that they themselves have changed, the patients lay emphasis on a change in the outer world which seems dead or macabre. (p.157; cited in Kendler, 2016 )

This idea of the external world feeling distant or dead is a leitmotif in much of the psychiatric literature on depression. When clinicians ask depressed patients to describe their symptoms, what is most frequently identified is lethargy and inability to act; but after that is a sense of detachment from the world (Healy, 1993 ; Rottenberg, 2005 ). Ratcliffe ( 2014 ) characterises the first-person experience of this ‘detachment’ as follows:

The practical significance of things is somehow diminished; they no longer offer up the usual possibilities for activity. Associated with this, there may be a sense of impossibility; possibilities appear as ‘there but impossible to actualize’. There can also be a sense of estrangement, as possibilities that are inaccessible to the self appear as ‘accessible to others with little effort’. Other people might continue to offer possibilities for communion, but these possibilities appear at the same time as ‘impossible for me to take up’. Together, these alterations in the possibility space constitute a feeling of isolation, which is experienced as irrevocable because depression does not include a sense of its own contingency. The resultant estrangement from the world amounts to a change in the sense of reality and belonging—things no longer appear available; they are strangely distant, not quite ‘there’ anymore. Certain kinds of possibility may also be heightened. A world that no longer offers up invitations to act can at the same time take the form of an all-enveloping threat, before which one is passive, helpless and alone. ( 2014 p.71)

What the above two quotes highlight is that depression involves an element of derealisation, of the world’s feeling distant, strange and no longer fully there for one (perhaps co-present with a painful awareness that it once was effortlessly there, and currently is for others). Can this distinguish depression from grief? If so, then first-person features suffice here and appeal to causes of these conditions is unnecessary.

Those who defend the Irrationality View might object: derealisation suffices to distinguish depression from much normal sadness, but not intense, debilitating sadness like grief. For in grief one also feels detached, helpless and motivationally depleted, perhaps to the same degree as in depression. And yet, they may argue, depression is mental illness and grief is normal and natural. Hence, extrinsic, aetiological factors, proportionality to circumstance in particular, are necessary to distinguish the two.

In reply, consider a further phenomenal feature of depression: the felt inescapability of one’s derealised state. In grief, one may feel detached from the world in the exact same way as if one were depressed. But in non-pathological grief at least, one often has a sense that the painfulness shall pass. Depression, however, feels inescapable insofar as one feels that it shall never lift. This is what Ratcliffe implies when saying that depression is unique in failing to include a sense of its own contingency. And he is not alone in characterising depression in this manner. The clinical psychiatrist Kay R. Jamison does the same. Crucially, she does so when contrasting depression with grief. In her depression memoir, she writes:

Even during the worst of my grief I had some sense that this would happen, that the weather would clear. I did not have this faith during the merciless months of depression. ( 2009 , p.172)

It is here, in what we can call the felt inescapability of derealisation , that daylight can be found between first-personal features of grief and depression. The idea that grief and depression can only be distinguished by aetiological factors, as defenders of the Irrationality View claim, assumes an overly simplistic, if not false, picture of depression’s phenomenal character.

I suspect that the fault lies in defenders of the Irrationality View assuming that depression and grief are objectless moods sharing identical, intrinsic phenomenal qualities. On this assumption, the experience of depression and grief can only differ in the magnitude of those phenomenal qualities. On this account, neither depression nor grief has any intentional structure to speak of. Footnote 12 But this seems false to grief in particular. Grief has as its intentional object the absence in the external world of a particular individual , whether that is an object or person. One grieves for the loss of something. While depression might also be said to involve experiencing the absence of something—namely one’s agency or ability to act—this would still not suffice to make grief and depression phenomenally indistinguishable in ways that would motivate an appeal to extrinsic facts to distinguish the two. The phenomenal character of depression would remain primarily self-focussed in ways that grief is primarily other-focussed, though both would share a sense, perhaps secondarily or indirectly, of the external world as flat and colourless.

The suggestion here is that both depression and grief have something of a twofold phenomenology in which one thing, the world, feels dead to one through its absence of some other thing. However, in grief, the world feels dead through its being found to be absent of a loved one or thing. But in depression the world feels dead to one through its absence of oneself, in a manner of speaking, insofar as one’s ability to act in the world feels agonisingly absent.

My claim then is that the difference in phenomenal character between depression and grief goes beyond a difference in the felt inescapability of derealisation , as identified by Ratcliffe. It also includes a difference in what we may call self-/other-focussed intentionality . Crucially, the contrast here with grief is not a difference of mere degree, i.e. in intensity or duration of negative affect. The difference is one of intentional-cum-phenomenological structure. This is therefore a difference in kind. Footnote 13

This is not an exhaustive account of the first-person, phenomenal differences (and similarities) between depression and grief. Footnote 14 But thinking about the difference between depression and grief in terms of self-/other-focussed intentionality , in the above manner, is apt for a number of reasons. First, the appeal to a common twofold structure explains how one might mistakenly think there is no phenomenal difference between depression and grief, as defenders of the Irrationality View insinuate. Second, the twofold structure described above explains how, in the case of depression in particular, a patient’s experience may vacillate between the world’s feeling broken versus oneself feeling broken, a feature of the condition reflected in Curran’s and Guttman’s remarks, as well as Ratcliffe’s too. My suggestion is that this is akin to perceptual aspect-switching. For instance, when looking at a picture, one may alternate attention between what is depicted in the surface and the marks in which it is depicted (Gombrich, 1960 ; Budd, 1987 ) but one can also, arguably, experience both together, as two, united ‘folds’ of a single experience (Wollheim, 1980 ).

So individuating depression by reference to extrinsic facts, as the Irrationality View does, is unmotivated and redundant. Depression has first-person, phenomenal features of inescapability and self-focussed intentionality that already distinguish it from even the most intense forms of normal, healthy sadness. Appealing to extrinsic facts is simply not necessary here. Thus, the master argument for the Irrationality View relies on a naïve, if not false, view of the phenomenal character of depression.

5 How not to defend the mixed view

So far I have gone on the offensive against the Irrationality View. It’s now time to defend the Mixed View against objections.

5.1 Two problems

The Mixed View says that some events, traumatic ones in particular, are so unbearable that they rationalise depression. The view rejects the idea that it is a conceptual truth that depression is without justification in adverse life events. In doing so, it rejects the idea that depression is necessarily aetiologically irrational. It therefore also rejects the externalism of the Irrationality View.

What does the Mixed View say about individuals who undergo unbearable events, but do not become depressed? Suppose that Sam, having come face-to-face with some of the worst, most dispiriting and traumatic experiences that life can offer, does not, as a result, become depressed. Ordinarily, we would see this as fortunate. By being psychologically unscathed by trauma, Sam has narrowly avoided mental illness. Intuitively, there is nothing problematic in this at all—quite the opposite.

But defenders of the Mixed View seem forced to say otherwise. The Mixed View considers Sam, and those in similar situations, to be, as Graham says “justified for depression” ( 1990 , p.400). So insofar as Sam is not, in fact, depressed, the Mixed View seems to entail that Sam is rationally sub-optimal. It would be aetiologically rational for Sam to be depressed, on the Mixed View, so insofar as they are not, they are missing out. After all, being merely justified for a mental state is not as good, from a rational point of view, as being justified for a mental state and then actually being in that state . Compare: it is financially good to be approved for a loan from the bank (in a situation in which you need funds quickly), but what really matters is that you are approved for the loan and the money then sits in your account . Merely having the loan approved, but not actually possessing the money, is financially sub-optimal. By a parity of reasoning, defenders of the Mixed View seem forced to say that Sam is likewise missing out, albeit rationally. But this seems absurd. It is good that Sam is not depressed and in no sense bad, rational or otherwise. Call this problem for the Mixed View ‘the problem of unfortunate near misses.’

There is a second problem in the vicinity when we consider what factors might prevent one for whom, on the Mixed View, it would be aetiologically rational to be depressed, from actually being depressed. First, it might be down to one’s character. Suppose that Priya is sufficiently resilient that intolerable events fail to cause her to be depressed. After a string of appalling experiences, she simply ‘toughens up’ further still. Mental resilience, psychological fortitude, etc. is normally thought to be a good thing. But the Mixed View seems forced to say that it is bad here, at least from a rational point of view. In this case, it has prevented Priya from reaching her full rational potential insofar as it bars her from being in a state that it is aetiologically rational for her to be in.

Someone in a similar position is Aaron. Having lived through traumatic events, he finds himself despondent to an extent he has never experienced before and worries he is sliding into depression. So he actively works to keep the condition at bay. Aaron talks through his experiences with a psychotherapist, takes increased exercise, has a meditation schedule, makes time for friends and family, etc. The Mixed View again seems forced to say that, from the point of view of rationality, Aaron is doing things wrong. His strategies for keeping depression at bay are, like Priya’s resilience, preventing him from being in a psychological state that it would be aetiologically rational for him to be in. The Mixed View seems forced to say that he would be more (aetiologically) rational if he simply yielded to his emerging depression and that his coping strategies are keeping him in a rationally sub-optimal situation.

In all this, the Mixed View seems to produce incorrect verdicts. It treats psychological resilience and coping strategies as rationally remiss insofar as they prevent persons for whom it would be rational to be depressed, like Priya and Aaron, from being, in fact, depressed. But the idea that mental resilience and healthy coping strategies are in any way bad is highly counterintuitive. Call this second problem ‘the problem of remiss resilience.’

Taken together, the problems of unfortunate near misses and remiss resilience constitute a dual-headed reductio of the Mixed View. And they have a common root: the Mixed View’s claim that depression is ever rationally instantiated in the first place. The Irrationality View says that it is a conceptual truth that depression is necessarily irrational. So, on that view, the problem of unfortunate near misses does not arise: on the Irrationality View, being depressed is never rational, so failing to be depressed is never rationally sub-optimal. Likewise, on the Irrationality View, psychological resilience to depression and healthy coping strategies are always rationally beneficial; they prevent people like Priya and Aaron from being in what is, on that view, an intrinsically irrational mental state. And for that reason, the problem of remiss resilience does not arise on the Irrationality View either. So, for all of the problems facing the Irrationality View, it appears to claim a substantial victory here over the Mixed View. How might a defender of the latter view reply?

5.2 The hard-line reply

One reply on behalf of the Mixed View is the ‘hard-line’ reply. It digs in its heels and bites the bullet. Faced with the problem of unfortunate near misses, the hard-line reply says that if a person would be rationally better off depressed, by being in a state that it would be aetiologically rational for them to be in, then so be it. On this view, insofar as Sam, having lived through various traumatic events, fails to be depressed, they really are in a rationally sub-optimal situation. Moreover, insofar as Priya’s resilience and Aaron’s coping strategies prevent them from being depressed, resilience and coping strategies are, in fact, rationally problematic. On the hard-line reply, there really is, from a rational point of view, such a thing as unfortunate near-misses with depression and remiss resilience to the condition. On this view, a person’s failing to be depressed in sufficiently traumatic circumstances entails that something is wrong with them, just as the same might be said about a person’s failing to experience grief upon the death of a loved one.

How might these claims be substantiated? Consider the following remarks by Graham ( 1990 ):

[W]ere a person immune to depression in justifiably depressed circumstances, I think we should be inclined to think of him as psychologically deficient. Such an individual would either be self-deceived about his situation (‘It’s not a death camp but a training center’) or expressing some emotional confusion, or in some way other impaired. (p.419)

Seemingly, Graham defends the hard-line reply. He argues that someone for whom depression is aetiologically rational, but who is not in fact depressed, must thereby fail to comprehend the appallingness of their situation. Being justified for depression, life must be bad, terrible even, for persons like Sam, Priya and Aaron. But not actually being depressed, Graham thinks that they must have little idea of this fact. Accordingly, I take it that Graham’s view is that whatever has prevented such would-be depressives from being depressed is rationally problematic. Whether we are talking about sheer luck (in the case of Sam), resilience (in the case of Priya) or healthy coping strategies (in the case of Aaron), such factors preclude individuals for whom depression is justified from cognising their situation and wider world for what it is (p.419).

What should we make of the hard-line reply? Doubtless there are some for whom Graham’s comments apply. For instance, if sheer obliviousness explains why Sam fails to be depressed, then we should agree that they are psychologically deficient in some way. After all, if Sam is oblivious to great trauma and suffering in their life, then they would seem rationally sub-optimal to begin with. For instance, suppose that Sam is a frontline soldier and exhibits excessive cheerfulness or joyfulness in the face of horrific tragedy and inhumanity. Then, we might suspect that Sam’s broader evaluative outlook fails to accurately track the reality of the situation around them.

However, contrary to the hard-line reply, it is not true that the only way to make sense of Sam’s failure to be depressed in the face of trauma is by giving descriptions of them as rationally sub-par. Perhaps Sam is just built differently. They need not be psychologically resilient per se and they need not be unaware of the difficulties of their situation. For they need not be emotionally unaffected by the challenges they face; they simple need not be depressed as a result of their situation. Failing to be depressed in dire circumstances need not indicate that one is psychologically deficient. After all, Sam may still be upset, worried, sombre, etc.

So, as a general statement regarding those for whom it is aetiologically rational to be depressed, but who are not, Graham’s remarks do not ring true. Indeed, consider Priya and Aaron. As a psychologically resilient person, Priya need not be at all oblivious, self-deceived or emotionally stunted. After all, being psychologically resilient is not the same as being emotionally unintelligent. Moreover, as someone who takes themselves to be vulnerable to depression, it is unlikely that Aaron’s enacting various coping strategies entails, by itself, obliviousness about his situation. Quite the opposite is true: aaron exhibits by his actions a significant degree of self-awareness and attentiveness to his circumstances. Graham is certainly right that psychological resilience and coping strategies may prevent one from being attuned to the horrors of one’s situation. But they need not do so necessarily. A person can be fully aware that life is bad for them, but attempt to meet its challenges head on instead of shrinking away, all without being psychologically deficient.

One way that Graham attempts to support his hard-line reply is by reference to the thesis of ‘depressive realism’ ( 1990 , p.416 though he doesn’t use the term; see also Martin, 1999 and Ratnayake, 2022 ). Depressive realism is the thesis that through involving a negative outlook, depression attenuates one’s overly positive biases. The result is more accurate and sober assessments of reality and one’s own abilities. According to depressive realism, depression is something of a rational upgrade, as the hard-line reply insinuates. As a result, factors that prevent justified, would-be depressives like Sam, Priya and Aaron from being depressed—whether that is luck, psychological resilience or coping strategies—must be considered rationally remiss. On the line of argument currently being considered, that is not because of their ‘backward looking’ property of preventing justified instantiations of depression. Rather, barriers to depression are now being criticised for their having the ‘forward looking’ property of preventing people like Sam, Priya and Aaron from going on to have a greater number of true beliefs (or more accurate degrees of belief) than they would have otherwise.

The evidence for depressive realism, and which Graham approvingly cites, is the performance of depressed subjects on tests measuring the ability to accurately judge one’s capacity to control certain events, e.g., a light’s turning on (Alloy & Abramson, 1979 ; see Moore & Fresco, 2012 for a review). Strikingly, depressed individuals have been found to perform better in such tests than non-depressed individuals. The latter subjects were instead found to suffer an ‘illusion of control’, overestimating their ability to influence, and so having false beliefs about their ability to control, the relevant happenings. Since the depressed individuals in these tests had fewer false beliefs, perhaps depression can, from the point of view of rationality, be a good thing.

We shouldn’t be so quick. Although some join Graham in affirming the thesis of depressive realism (Ratnayake, 2022 ), experiments on the effect have been criticised on multiple fronts, by philosophers (Bermudez 2001 , pp.484-6; Ratcliffe, 2014 , pp.272-3) and psychologists (Ackermann & DeRubeis, 1991 ; Allan et al., 2007 ) alike. Misgivings run the gamut, from concerns about a lack of objective measures in the experiments, to worries about the limitedness of their conclusions, to objectons about their inapplicability to real-life situations. More problematic for Graham is that the effect does not reliably replicate. Some psychologists found no illusion of control whatsoever, in depressed or non-depressed groups (Bryson et al., 1984 ). Others have reported the opposite effect; namely, that an illusion of control is present in both depressed and non-depressed groups (Kapçi & Cramer, 1999 ). These results undercut the thesis of depressive realism. They thereby undercut Graham’s support for the hard-line reply that depression is a rational upgrade.

So, Graham’s hard-line reply to the dual reductio objection outlined in 5.i is not only inapplicable to certain people who fail to be depressed, it is ill-supported more generally. Thus, it is worth exploring other solutions to these problems. At the very least, it is worth seeing whether the Mixed View has the flexibility to handle the problems of 5.i in ways that do not require bullet-biting on whether people who have lived through serious trauma but fail to be depressed are, ipso facto , rationally sub-optimal.

6 How to defend the mixed view

In this final section, I develop a different version of the Mixed View, one that offers a novel response to the problems of unfortunate near misses and remiss resilience. This version of the Mixed View departs from Graham’s hard-line version by attempting to vindicate the idea that it is never rationally fortunate to be depressed and that resilience to depression and coping strategies are never rationally remiss. These claims are also affirmed by the Irrationality View. So, if the Mixed View can be shown to make room for them too, then the playing field between the two views will be levelled somewhat.

First, consider that there are a multitude of empirically confirmed, rational harms of depression. As a recent meta-analytic review puts it, depression is “associated with significant moderate deficits across all tasks within the domains of executive function, memory and attention” (Rock et al., 2014 , p.2034). A small sample of these cognitive impairments, and some of their implications for rationality, includes the following:

Depressed individuals perform worse, on average, than non-depressed individuals on tasks measuring the ability to discard false beliefs (Silberman et al., 1983 ).

Depressed individuals are more likely, on average, to have ‘overly-general’, i.e. less fine-grained, memories than non-depressed individuals (Evans et al., 1992 ).

Depressed individuals perform worse, on average, than non-depressed individuals on tasks measuring the ability to generate mental imagery of the future (Williams et al., 1996 ).

Depressed individuals perform worse, on average, than non-depressed individuals on tasks measuring social, problem-solving abilities (Goddard et al., 1996 ).

Let us take these in turn. ( 1 ) suggests that depression puts one at risk of having a greater number of false beliefs than one might have otherwise. ( 2 ) suggests that depression risks attenuating the number of propositions about the past that one is justified in believing. ( 3 ) suggests that depression risks attenuating the number of futurity-related propositions that one is justified in believing, as well as hampering decision-making and planning, insofar as these may involve imagery (Nanay, 2016 ). ( 4 ) suggests that depression risks interfering with one’s ability to relate to and understand others; indeed, impaired psychosocial functioning is often considered a “core feature” of depression (Rock et al., 2014 , p.2035).

Moreover, these cognitive impairments often persist after remission from depression (Hasselbalch et al., 2011 ). That is, they don’t simply go away once one is no longer depressed. So depression, however else one characterises it, entails significant and long-standing rational degradation. Depression is most definitely not a rational upgrade, as claimed by Graham and friends of depressive realism.

All this leaves defenders of the Mixed View who wish to refuse Graham’s hard-line variant in something of a bind: on the one hand, they claim it is intuitive to think that some people (those who have suffered great trauma) are aetiologically rational in being depressed. On the other hand, we’ve just seen that depression involves rational degradation. So is it rationally good to be depressed or isn’t it? I think that a defender of the Mixed View can see their way clear of this dilemma by adopting a broadly consequentialist view of epistemic rationality.

To begin, compare the rational merit of being in a state that it is aetiologically rational for one to be in, with the rational disvalue of the harms represented by (1)–(4) . I think it is clear that the latter greatly outweighs the former. We should agree: it is rationally beneficial to be in a state which, given the circumstances, it is aetiologically to be in. However, this is not to say that depression is, from a rational point of view, a good thing en toto . If the rational costs of being depressed are severe, which they appear to be, going by (1)–(4) , then it would be overall better, from a rational point of view, for people like Sam, Priya and Aaron not to be depressed. So although factors like luck, psychological resilience and coping strategies may, for those that have them, prevent aetiologically rational instantiations of depression, these factors are rationally beneficial (in the context of depression at least) since they prevent a dramatic increase in overall rational disvalue for a person. Analogously, it may be financially good to be approved for a loan from the bank and then have the money sitting in one’s account. But it is not financially good en toto if having that extra money causes one to lose money overall, e.g., if the interest and repayment fees are so exorbitant that they wipe out most of one’s savings. This is how I claim things stand with depression. Thus, the Mixed View can accommodate the common sense idea that, when it comes to depression, luck, psychological resilience and coping strategies are good things insofar as they prevent one from being depressed, given all the rational harms that come with it. Most important of all, the Irrationality View doesn’t claim a victory here over the Mixed View. Both views can agree: it is not rationally better to be depressed than not, and luck, resilience and coping strategies are not rationally remiss, but valuable. If you want to affirm these claims, you need not reject the Mixed View for the Irrationality View.

This solution to the dual reductio of unfortunate near misses and remiss resilience bears the hallmarks of epistemic consequentialism (see Percival, 2002 ; Dunn & Ahlstrom-Vij, 2017 ; Singer, 2018 ), a view that has provided a useful perspective on other forms of psychological disorder (Bortolotti & Miyazono, 2016 ). Accordingly, we can call it the ‘consequentialist reply.’ Here are some important consequentialist features.

First, in handling the problem of unfortunate near misses, the view endorses a trade-off . It says that some rational value ought to be given up, if doing so will secure greater rational gains. The reply doesn’t, or at least need not, reject the idea that it is sub-optimal for a person to fail to be in a state that, given the circumstances, it is aetiologically rational for them to be in. But the reply insists that the additional rational good of actually being in that state may be sacrificed, if actually being in that state means being in a situation that is overall rationally worse for the person.

Second, in handling the problem of remiss resilience, the reply says that barriers to depression like resilience and coping strategies are rationally valuable in a particular way; namely, teleologically , in a forward-looking, means-ends manner. In particular, resilience and coping strategies are pictured as rationally valuable insofar as they are tools for the creation of rationally good situations and the evasion of rationally bad ones. That is, the rational goodness of resilience and coping strategies is (in this context) a matter of them being means for avoiding the rational harms of (1)–(4) being actualised by virtue of them preventing depression from being instantiated.

Third, the reply is couched in terms of totalizing the relevant rational outcomes. When thinking about depression, the reply urges us to focus on total rational goodness and badness. The reply claims that the degree to which a person’s overall rationality would be compromised by depression, as evidenced by (1)–(4), eclipses the rational goodness of being in a state that it is aetiologically rational for one to be in. It is important to be clear on how this last claim does not go against the idea at the heart of the Mixed View: depression can remain an aetiologically rational response to the (apparent) events in one’s life; it is just that, it is overall rationally sub-optimal to be depressed, given (1)–(4). These claims are not contrary to one another since the latter concerns the total rational value of a situation in which someone is depressed, while the former concerns the rational value of one element of the situation: its aetiology.

In sum, then, contrary to appearances, the Mixed View is not forced to say, with Graham, that barriers to depression e.g., luck, resilience or coping strategies, are rationally problematic. It is epistemically rational for people who have experienced trauma to be depressed; yet at the same time, such individuals are not rationally sub-optimal if they fail to in fact be depressed. If one finds this combination of claims attractive, then the Mixed View, coupled with epistemic consequentialism, shows how they may both be affirmed. The Irrationality View need not be affirmed along the hard-line manner endorsed by Graham. Footnote 15

7 Conclusion

Where the Irrationality View sees in depressed individuals only rational failings, the Mixed View seeks to acknowledge the dreadfulness of some people’s lives. Sometimes things can be so bad as to make depression a reasonable response from the point of view of epistemic rationality. Those who are depressed need not be responding incorrectly to the facts as they see them—they may be perfectly attuned to the horrors of their situation. I have argued that this view is a serious competitor to the Irrationality View in terms of how we ought to understand the relationship between depression and epistemic rationality. In particular, I have argued that the Irrationality View does not obviously receive greater support from the current clinical literature than the Mixed View. Moreover, I have argued that the Irrationality View assumes a simplistic account of depression’s phenomenal character. In terms of supporting the Mixed View, I have argued that epistemic consequentialism offers a novel response to two problems that beset one of the few existing defences of the theory, i.e. Graham’s. Granted, this still leaves a great deal up in the air, regarding aetiological rationality, depression itself, epistemic consequentialism, and so on. I leave these challenging questions for another time.

In sum, the Irrationality View does not obviously deserve to be the preferred account of the rationality of depression. The Mixed View is equally as attractive, if not more so in certain respects.

This view of grief as necessarily rational might be challenged (Wilkinson, 2000 ), but I will grant it for the sake of argument. Moreover, there are puzzles concerning grief’s rationality; namely, how grief can rightly diminish with time when reasons to grieve don’t (Marušić, 2018 ).

I offer these as intuitive examples of the kinds of situation severe enough to make depression an epistemically rational, epistemically well-supported or fitting response. I am not wedded to these, and only these, examples as constituting the relevant category.

See also Martin ( 1999 ) and Ratnayake ( 2022 ).

Bortolotti ( 2020 , p.1), in her discussion of the rationality of mental health conditions, calls the first kind of irrationality a matter of a mental state’s being ill-grounded and the second a matter of its being impervious to counterevidence .

Externalists about justification can drop the modifier ‘apparent’, both here and in the statements of the Irrationality View and the Mixed View provided above. From here on, I will drop the modifier, purely for ease.

On persecutory delusions, see Bentall et al. ( 2001 ); Radden ( 2006 ); and Bortolotti ( 2010 , pp.68–73).

I say ‘typically’ because of the difficulty of accounting for so-called ‘masked depression’, in which patients report somatic complaints rather than psychological ones, e.g., in cultures where psychological suffering is taken to be a sign of weakness (see Cooper, 2012 , pp.200–201 for a philosophical discussion of the condition).

My discussion will have some negative consequences, however. In Sect.  4 I will argue that depression has a certain phenomenological-cum-intentional structure which is at odds with depression’s being an objectless mood.

I suspect that Ratcliffe’s ( 2014 ) and Whiteley’s (forthcoming) views may fall into this camp. In particular, existential feelings and global states of consciousness do not seem to have rationally appraisable aetiologies; consider, in this respect, dreaming, drunkardness or fatigue.

Insofar as the Arationality View suggests there is, from the point of view of rationality, no difference between mental and physical health conditions, it seems to me substantially challenged by Arpaly ( 2005 ).

Although the depression/grief contrast is only implicit in the writings of some defenders of the Irrationality View, it is especially explicit in Horwitz and Wakefield ( 2007 ).

See Kind ( 2013 ) for discussion of this view in relation to depression. The view that depression is an objectless mood seems defended by Deonna and Teroni ( 2012 ), pp.105–106.

In saying this, I disagree with Michael Cholbi’s ( 2017 ) claim that grief is essentially self-concerning (insofar as its object is the loss of one’s own relationship with the deceased). I think the contrast with depression shows what a more genuinely self-concerning psychological state looks like. Moreover, I agree with Marušić ( 2018 , n.12) that, for all Cholbi says that is illuminating about grief, he may, on this subject, be conflating a background condition for grief with its proper intentional object.

See Ratcliffe ( 2014 p.107; also his 2020 ) as well as Richardson ( 2023 ) on grief in particular.

Epistemic consequentialism figures in the background of Graham’s defence of the Mixed View too. By endorsing the thesis of depressive realism, he focuses on depression (mistakenly, I have argued) being a rational upgrade via arguing it may cause more accurate judgments of control.

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Acknowledgements

Thanks to colleagues at the Open University for comments on an earlier version and to the generous and insightful comments from three of this journal’s anonymous referees. In addition, Craig French, Uriah Kriegel and Adam Linson all offered helpful comments on drafts at various stages of development.

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Cavedon-Taylor, D. Must depression be irrational?. Synthese 204 , 79 (2024). https://doi.org/10.1007/s11229-024-04714-9

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What makes a good thesis statement?

  • It takes a position, or advances an opinion.
  • It is specific, not too broad, but not too narrow.
  • It is an arguable statement; there is room for discussion or disagreement.
  • It provides focus and generates interest in the reader.

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ercise, combined with antidepressants, is more effective in reducing depression in older adults given the prevalence of treatment-resistant depression in late life.

 

 

 

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How to Write a Thesis Statement | 4 Steps & Examples

Published on January 11, 2019 by Shona McCombes . Revised on August 15, 2023 by Eoghan Ryan.

A thesis statement is a sentence that sums up the central point of your paper or essay . It usually comes near the end of your introduction .

Your thesis will look a bit different depending on the type of essay you’re writing. But the thesis statement should always clearly state the main idea you want to get across. Everything else in your essay should relate back to this idea.

You can write your thesis statement by following four simple steps:

  • Start with a question
  • Write your initial answer
  • Develop your answer
  • Refine your thesis statement

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Table of contents

What is a thesis statement, placement of the thesis statement, step 1: start with a question, step 2: write your initial answer, step 3: develop your answer, step 4: refine your thesis statement, types of thesis statements, other interesting articles, frequently asked questions about thesis statements.

A thesis statement summarizes the central points of your essay. It is a signpost telling the reader what the essay will argue and why.

The best thesis statements are:

  • Concise: A good thesis statement is short and sweet—don’t use more words than necessary. State your point clearly and directly in one or two sentences.
  • Contentious: Your thesis shouldn’t be a simple statement of fact that everyone already knows. A good thesis statement is a claim that requires further evidence or analysis to back it up.
  • Coherent: Everything mentioned in your thesis statement must be supported and explained in the rest of your paper.

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The thesis statement generally appears at the end of your essay introduction or research paper introduction .

The spread of the internet has had a world-changing effect, not least on the world of education. The use of the internet in academic contexts and among young people more generally is hotly debated. For many who did not grow up with this technology, its effects seem alarming and potentially harmful. This concern, while understandable, is misguided. The negatives of internet use are outweighed by its many benefits for education: the internet facilitates easier access to information, exposure to different perspectives, and a flexible learning environment for both students and teachers.

You should come up with an initial thesis, sometimes called a working thesis , early in the writing process . As soon as you’ve decided on your essay topic , you need to work out what you want to say about it—a clear thesis will give your essay direction and structure.

You might already have a question in your assignment, but if not, try to come up with your own. What would you like to find out or decide about your topic?

For example, you might ask:

After some initial research, you can formulate a tentative answer to this question. At this stage it can be simple, and it should guide the research process and writing process .

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Now you need to consider why this is your answer and how you will convince your reader to agree with you. As you read more about your topic and begin writing, your answer should get more detailed.

In your essay about the internet and education, the thesis states your position and sketches out the key arguments you’ll use to support it.

The negatives of internet use are outweighed by its many benefits for education because it facilitates easier access to information.

In your essay about braille, the thesis statement summarizes the key historical development that you’ll explain.

The invention of braille in the 19th century transformed the lives of blind people, allowing them to participate more actively in public life.

A strong thesis statement should tell the reader:

  • Why you hold this position
  • What they’ll learn from your essay
  • The key points of your argument or narrative

The final thesis statement doesn’t just state your position, but summarizes your overall argument or the entire topic you’re going to explain. To strengthen a weak thesis statement, it can help to consider the broader context of your topic.

These examples are more specific and show that you’ll explore your topic in depth.

Your thesis statement should match the goals of your essay, which vary depending on the type of essay you’re writing:

  • In an argumentative essay , your thesis statement should take a strong position. Your aim in the essay is to convince your reader of this thesis based on evidence and logical reasoning.
  • In an expository essay , you’ll aim to explain the facts of a topic or process. Your thesis statement doesn’t have to include a strong opinion in this case, but it should clearly state the central point you want to make, and mention the key elements you’ll explain.

If you want to know more about AI tools , college essays , or fallacies make sure to check out some of our other articles with explanations and examples or go directly to our tools!

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A thesis statement is a sentence that sums up the central point of your paper or essay . Everything else you write should relate to this key idea.

The thesis statement is essential in any academic essay or research paper for two main reasons:

  • It gives your writing direction and focus.
  • It gives the reader a concise summary of your main point.

Without a clear thesis statement, an essay can end up rambling and unfocused, leaving your reader unsure of exactly what you want to say.

Follow these four steps to come up with a thesis statement :

  • Ask a question about your topic .
  • Write your initial answer.
  • Develop your answer by including reasons.
  • Refine your answer, adding more detail and nuance.

The thesis statement should be placed at the end of your essay introduction .

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434 Depression Essay Titles & Research Topics: Argumentative, Controversial, and More

Depression is undeniably one of the most prevalent mental health conditions globally, affecting approximately 5% of adults worldwide. It often manifests as intense feelings of hopelessness, sadness, and a loss of interest in previously enjoyable activities. Many also experience physical symptoms like fatigue, sleep disturbances, and appetite changes. Recognizing and addressing this mental disorder is extremely important to save lives and treat the condition.

In this article, we’ll discuss how to write an essay about depression and introduce depression essay topics and research titles for students that may be inspirational.

  • 🔝 Top Depression Essay Titles
  • ✅ Essay Prompts
  • 💡 Research Topics
  • 🔎 Essay Titles
  • 💭 Speech Topics
  • 📝 Essay Structure

🔗 References

🔝 top 12 research titles about depression.

  • How is depression treated?
  • Depression: Risk factors.
  • The symptoms of depression.
  • What types of depression exist?
  • Depression in young people.
  • Differences between anxiety and depression.
  • The parents’ role in depression therapy.
  • Drugs as the root cause of depression.
  • Dangerous consequences of untreated depression.
  • Effect of long-term depression.
  • Different stages of depression.
  • Treatment for depression.

The picture provides a list of topics for a research paper about depression.

✅ Prompts for Essay about Depression

Struggling to find inspiration for your essay? Look no further! We’ve put together some valuable essay prompts on depression just for you!

Prompt for Personal Essay about Depression

Sharing your own experience with depression in a paper can be a good idea. Others may feel more motivated to overcome their situation after reading your story. You can also share valuable advice by discussing things or methods that have personally helped you deal with the condition.

For example, in your essay about depression, you can:

  • Tell about the time you felt anxious, hopeless, or depressed;
  • Express your opinion on depression based on the experiences from your life;
  • Suggest a way of dealing with the initial symptoms of depression ;
  • Share your ideas on how to protect mental health at a young age.

How to Overcome Depression: Essay Prompt

Sadness is a common human emotion, but depression encompasses more than just sadness. As reported by the National Institute of Mental Health, around 21 million adults in the United States, roughly 8.4% of the total adult population , faced at least one significant episode of depression in 2020. When crafting your essay about overcoming depression, consider exploring the following aspects:

  • Depression in young people and adolescents;
  • The main causes of depression;
  • The symptoms of depression;
  • Ways to treat depression;
  • Help from a psychologist (cognitive behavioral therapy or interpersonal therapy ).

Postpartum Depression: Essay Prompt

The birth of a child often evokes a spectrum of powerful emotions, spanning from exhilaration and happiness to apprehension and unease. It can also trigger the onset of depression. Following childbirth, many new mothers experience postpartum “baby blues,” marked by shifts in mood, bouts of tears, anxiety, and sleep disturbances. To shed light on the subject of postpartum depression, explore the following questions:

  • What factors may increase the risk of postpartum depression?
  • Is postpartum depression predictable?
  • How to prevent postpartum depression?
  • What are the symptoms of postpartum depression?
  • What kinds of postpartum depression treatments exist?

Prompt for Essay about Teenage Depression

Teenage depression is a mental health condition characterized by sadness and diminishing interest in daily activities. It can significantly impact a teenager’s thoughts, emotions, and behavior, often requiring long-term treatment and support.

By discussing the primary symptoms of teenage depression in your paper, you can raise awareness of the issue and encourage those in need to seek assistance. You can pay attention to the following aspects:

  • Emotional changes (feelings of sadness, anger, hopelessness, guilt, etc.);
  • Behavioral changes (loss of energy and appetite , less attention to personal hygiene, self-harm, etc.);
  • New addictions (drugs, alcohol, computer games, etc.).

💡 Research Topics about Depression

  • The role of genetics in depression development.
  • The effectiveness of different psychotherapeutic interventions for depression.
  • Anti-depression non-pharmacological and medication treatment.
  • The impact of childhood trauma on the onset of depression later in life.
  • Exploring the efficacy of antidepressant medication in different populations.
  • The impact of exercise on depression symptoms and treatment outcomes.
  • Mild depression: pharmacotherapy and psychotherapy.
  • The relationship between sleep disturbances and depression.
  • The role of gut microbiota in depression and potential implications for treatment.
  • Investigating the impact of social media on depression rates in adolescents.
  • Depression, dementia, and delirium in older people .
  • The efficacy of cognitive-behavioral therapy in preventing depression relapse.
  • The influence of hormonal changes on depression risk.
  • Assessing the effectiveness of self-help and digital interventions for depression.
  • Herbal and complementary therapies for depression.
  • The relationship between personality traits and vulnerability to depression.
  • Investigating the long-term consequences of untreated depression on physical health.
  • Exploring the link between chronic pain and depression.
  • Depression in the elderly male.
  • The impact of childhood experiences on depression outcomes in adulthood.
  • The use of ketamine and other novel treatments for depression.
  • The effect of stigma on depression diagnosis and treatment.
  • The conducted family assessment: cases of depression.
  • The role of social support in depression recovery.
  • The effectiveness of online support groups for individuals with depression.
  • Depression and cognitive decline in adults.
  • Depression: PICOT question component exploration .
  • Exploring the impact of nutrition and dietary patterns on depression symptoms.
  • Investigating the efficacy of art-based therapies in depression treatment.
  • The role of neuroplasticity in the development and treatment of depression.
  • Depression among HIV-positive women.
  • The influence of gender on depression prevalence and symptomatology.
  • Investigating the impact of workplace factors on depression rates and outcomes.
  • The efficacy of family-based interventions in reducing depression symptoms in teenagers.
  • Frontline nurses’ burnout, anxiety, depression, and fear statuses.
  • The role of early-life stress and adversity in depression vulnerability.
  • The impact of various environmental factors on depression rates.
  • Exploring the link between depression and cardiovascular health.
  • Depression detection in adults in nursing practice.
  • Virtual reality as a therapeutic tool for depression treatment.
  • Investigating the impact of childhood bullying on depression outcomes.
  • The benefits of animal-assisted interventions in depression management.
  • Depression and physical exercise.
  • The relationship between depression and suicidal behavior.
  • The influence of cultural factors on depression symptom expression.
  • Investigating the role of epigenetics in depression susceptibility.
  • Depression associated with cognitive dysfunction.
  • Exploring the impact of adverse trauma on the course of depression.
  • The efficacy of acceptance and commitment therapy in treating depression.
  • The relationship between depression and substance use disorders .
  • Depression and anxiety among college students.
  • Investigating the effectiveness of group therapy for depression.
  • Depression and chronic medical conditions.

Psychology Research Topics on Depression

  • The influence of early attachment experiences on the development of depression.
  • The impact of negative cognitive biases on depression symptomatology.
  • Depression treatment plan for a queer patient .
  • Examining the relationship between perfectionism and depression.
  • The role of self-esteem in depression vulnerability and recovery.
  • Exploring the link between maladaptive thinking styles (e.g., rumination, catastrophizing) and depression.
  • Investigating the impact of social support on depression outcomes and resilience.
  • Identifying depression in young adults at an early stage.
  • The influence of parenting styles on the risk of depression in children and adolescents.
  • The role of self-criticism and self-compassion in depression treatment.
  • Exploring the relationship between identity development and depression in emerging adulthood.
  • The role of learned helplessness in understanding depression and its treatment.
  • Depression in the elderly.
  • Examining the connection between self-efficacy beliefs and depression symptoms.
  • The influence of social comparison processes on depression and body image dissatisfaction.
  • Exploring the impact of trauma-related disorders on depression.
  • The role of resilience factors in buffering against the development of depression.
  • Investigating the relationship between personality traits and depression.
  • Depression and workplace violence .
  • The impact of cultural factors on depression prevalence and symptom presentation.
  • Investigating the effects of chronic stress on depression risk.
  • The role of coping strategies in depression management and recovery.
  • The correlation between discrimination/prejudice and depression/anxiety.
  • Exploring the influence of gender norms and societal expectations on depression rates.
  • The impact of adverse workplace conditions on employee depression.
  • Investigating the effectiveness of narrative therapy in treating depression.
  • Cognitive behavior and depression in adolescents .
  • Childhood emotional neglect and adult depression.
  • The influence of perceived social support on treatment outcomes in depression.
  • The effects of childhood bullying on the development of depression.
  • The impact of intergenerational transmission of depression within families.
  • Depression in children: symptoms and treatments.
  • Investigating the link between body dissatisfaction and depression in adolescence.
  • The influence of adverse life events and chronic stressors on depression risk.
  • The effects of peer victimization on the development of depression in adolescence.
  • Counselling clients with depression and addiction.
  • The role of experiential avoidance in depression and its treatment.
  • The impact of social media use and online interactions on depression rates.
  • Depression management in adolescent.
  • Exploring the relationship between emotional intelligence and depression symptomatology.
  • Investigating the influence of cultural values and norms on depression stigma and help-seeking behavior.
  • The effects of childhood maltreatment on neurobiological markers of depression.
  • Psychological and emotional conditions of suicide and depression.
  • Exploring the relationship between body dissatisfaction and depression.
  • The influence of self-worth contingencies on depression vulnerability and treatment response.
  • The impact of social isolation and loneliness on depression rates.
  • Psychology of depression among college students.
  • The effects of perfectionistic self-presentation on depression in college students.
  • The role of mindfulness skills in depression prevention and relapse prevention.
  • Investigating the influence of adverse neighborhood conditions on depression risk.
  • Personality psychology and depression.
  • The impact of attachment insecurity on depression symptomatology.

Postpartum Depression Research Topics

  • Identifying risk factors for postpartum depression.
  • Exploring the role of hormonal changes in postpartum depression.
  • “Baby blues” or postpartum depression and evidence-based care .
  • The impact of social support on postpartum depression.
  • The effectiveness of screening tools for early detection of postpartum depression.
  • The relationship between postpartum depression and maternal-infant bonding .
  • Postpartum depression educational program results.
  • Identifying effective interventions for preventing and treating postpartum depression.
  • Examining the impact of cultural factors on postpartum depression rates.
  • Investigating the role of sleep disturbances in postpartum depression.
  • Depression and postpartum depression relationship.
  • Exploring the impact of a traumatic birth experience on postpartum depression.
  • Assessing the impact of breastfeeding difficulties on postpartum depression.
  • Understanding the role of genetic factors in postpartum depression.
  • Postpartum depression: consequences.
  • Investigating the impact of previous psychiatric history on postpartum depression risk.
  • The potential benefits of exercise on postpartum depression symptoms.
  • The efficacy of psychotherapeutic interventions for postpartum depression.
  • Postpartum depression in the twenty-first century.
  • The influence of partner support on postpartum depression outcomes.
  • Examining the relationship between postpartum depression and maternal self-esteem.
  • The impact of postpartum depression on infant development and well-being.
  • Maternal mood symptoms in pregnancy and postpartum depression.
  • The effectiveness of group therapy for postpartum depression management.
  • Identifying the role of inflammation and immune dysregulation in postpartum depression.
  • Investigating the impact of childcare stress on postpartum depression.
  • Postpartum depression among low-income US mothers.
  • The role of postnatal anxiety symptoms in postpartum depression.
  • The impact of postpartum depression on the marital relationship.
  • The influence of postpartum depression on parenting practices and parental stress.
  • Postpartum depression: symptoms, role of cultural factors, and ways to support.
  • Investigating the efficacy of pharmacological treatments for postpartum depression.
  • The impact of postpartum depression on breastfeeding initiation and continuation.
  • The relationship between postpartum depression and post-traumatic stress disorder.
  • Postpartum depression and its identification.
  • The impact of postpartum depression on cognitive functioning and decision-making.
  • Investigating the influence of cultural norms and expectations on postpartum depression rates.
  • The impact of maternal guilt and shame on postpartum depression symptoms.
  • Beck’s postpartum depression theory: purpose, concepts, and significance .
  • Understanding the role of attachment styles in postpartum depression vulnerability.
  • Investigating the effectiveness of online support groups for women with postpartum depression.
  • The impact of socioeconomic factors on postpartum depression prevalence.
  • Perinatal depression: research study and design.
  • The efficacy of mindfulness-based interventions for postpartum depression.
  • Investigating the influence of birth spacing on postpartum depression risk.
  • The role of trauma history in postpartum depression development.
  • The link between the birth experience and postnatal depression.
  • How does postpartum depression affect the mother-infant interaction and bonding ?
  • The effectiveness of home visiting programs in preventing and managing postpartum depression.
  • Assessing the influence of work-related stress on postpartum depression.
  • The relationship between postpartum depression and pregnancy-related complications.
  • The role of personality traits in postpartum depression vulnerability.

🔎 Depression Essay Titles

Depression essay topics: cause & effect.

  • The effects of childhood trauma on the development of depression in adults.
  • The impact of social media usage on the prevalence of depression in adolescents.
  • “Predictors of Postpartum Depression” by Katon et al.
  • The effects of environmental factors on depression rates.
  • The relationship between academic pressure and depression among college students.
  • The relationship between financial stress and depression.
  • The best solution to predict depression because of bullying.
  • How does long-term unemployment affect mental health ?
  • The effects of unemployment on mental health, particularly the risk of depression.
  • The impact of genetics and family history of depression on an individual’s likelihood of developing depression.
  • The relationship between depression and substance abuse.
  • Child abuse and depression.
  • The role of gender in the manifestation and treatment of depression.
  • The effects of chronic stress on the development of depression.
  • The link between substance abuse and depression.
  • Depression among students at Elon University.
  • The influence of early attachment styles on an individual’s vulnerability to depression.
  • The effects of sleep disturbances on the severity of depression.
  • Chronic illness and the risk of developing depression.
  • Depression: symptoms and treatment.
  • Adverse childhood experiences and the likelihood of experiencing depression in adulthood.
  • The relationship between chronic illness and depression.
  • The role of negative thinking patterns in the development of depression.
  • Effects of depression among adolescents.
  • The effects of poor body image and low self-esteem on the prevalence of depression.
  • The influence of social support systems on preventing symptoms of depression.
  • The effects of child neglect on adult depression rates.
  • Depression caused by hormonal imbalance.
  • The link between perfectionism and the risk of developing depression.
  • The effects of a lack of sleep on depression symptoms.
  • The effects of childhood abuse and neglect on the risk of depression.
  • Social aspects of depression and anxiety.
  • The impact of bullying on the likelihood of experiencing depression.
  • The role of serotonin and neurotransmitter imbalances in the development of depression.
  • The impact of a poor diet on depression rates.
  • Depression and anxiety run in the family .
  • The effects of childhood poverty and socioeconomic status on depression rates in adults.
  • The impact of divorce on depression rates.
  • The relationship between traumatic life events and the risk of developing depression.
  • The influence of personality traits on susceptibility to depression.
  • The impact of workplace stress on depression rates.
  • Depression in older adults: causes and treatment.
  • The impact of parental depression on children’s mental health outcomes.
  • The effects of social isolation on the prevalence and severity of depression.
  • The role of cultural factors in the manifestation and treatment of depression.
  • The relationship between childhood bullying victimization and future depressive symptoms.
  • The impact of early intervention and prevention programs on reducing the risk of postpartum depression.
  • Treating mood disorders and depression.
  • How do hormonal changes during pregnancy contribute to the development of depression?
  • The effects of sleep deprivation on the onset and severity of postpartum depression.
  • The impact of social media on depression rates among teenagers.
  • The role of genetics in the development of depression.
  • The impact of bullying on adolescent depression rates.
  • Mental illness, depression, and wellness issues.
  • The effects of a sedentary lifestyle on depression symptoms.
  • The correlation between academic pressure and depression in students.
  • The relationship between perfectionism and depression.
  • The correlation between trauma and depression in military veterans.
  • Anxiety and depression during childhood and adolescence.
  • The impact of racial discrimination on depression rates among minorities.
  • The relationship between chronic pain and depression.
  • The impact of social comparison on depression rates among young adults.
  • The effects of childhood abuse on adult depression rates.

Depression Argumentative Essay Topics

  • The role of social media in contributing to depression among teenagers.
  • The effectiveness of antidepressant medication: an ongoing debate.
  • Depression treatment: therapy or medications?
  • Should depression screening be mandatory in schools and colleges?
  • Is there a genetic predisposition to depression?
  • The stigma surrounding depression: addressing misconceptions and promoting understanding.
  • Implementation of depression screening in primary care .
  • Is psychotherapy more effective than medication in treating depression?
  • Is teenage depression overdiagnosed or underdiagnosed: a critical analysis.
  • The connection between depression and substance abuse: untangling the relationship.
  • Humanistic therapy of depression .
  • Should ECT (electroconvulsive therapy) be a treatment option for severe depression?
  • Where is depression more prevalent: in urban or rural communities? Analyzing the disparities.
  • Is depression a result of chemical imbalance in the brain? Debunking the myth.
  • Depression: a serious mental and behavioral problem.
  • Should depression medication be prescribed for children and adolescents?
  • The effectiveness of mindfulness-based interventions in managing depression.
  • Should depression in the elderly be considered a normal part of aging?
  • Is depression hereditary? Investigating the role of genetics in depression risk.
  • Different types of training in managing the symptoms of depression.
  • The effectiveness of online therapy platforms in treating depression.
  • Should psychedelic therapy be explored as an alternative treatment for depression?
  • The connection between depression and cardiovascular health: Is there a link?
  • The effectiveness of cognitive-behavioral therapy in preventing depression relapse.
  • Depression as a bad a clinical condition.
  • Should mind-body interventions (e.g., yoga, meditation) be integrated into depression treatment?
  • Should emotional support animals be prescribed for individuals with depression?
  • The effectiveness of peer support groups in decreasing depression symptoms.
  • The use of antidepressants: are they overprescribed or necessary for treating depression?
  • Adult depression and anxiety as a complex problem.
  • The effectiveness of therapy versus medication in treating depression.
  • The stigma surrounding depression and mental illness: how can we reduce it?
  • The debate over the legalization of psychedelic drugs for treating depression.
  • The relationship between creativity and depression: does one cause the other?
  • Cognitive-behavioral therapy for generalized anxiety disorder and depression.
  • The role of childhood trauma in shaping adult depression: Is it always a causal factor?
  • The debate over the medicalization of sadness and grief as forms of depression.
  • Alternative therapies, such as acupuncture or meditation, are effective in treating depression.
  • Depression as a widespread mental condition.

Controversial Topics about Depression

  • The existence of “chemical imbalance” in depression: fact or fiction?
  • The over-reliance on medication in treating depression: are alternatives neglected?
  • Is depression overdiagnosed and overmedicated in Western society?
  • Measurement of an individual’s level of depression.
  • The role of Big Pharma in shaping the narrative and treatment of depression.
  • Should antidepressant advertisements be banned?
  • The inadequacy of current diagnostic criteria for depression: rethinking the DSM-5.
  • Is depression a biological illness or a product of societal factors?
  • Literature review on depression .
  • The overemphasis on biological factors in depression treatment: ignoring environmental factors.
  • Is depression a normal reaction to an abnormal society?
  • The influence of cultural norms on the perception and treatment of depression.
  • Should children and adolescents be routinely prescribed antidepressants?
  • The role of family in depression treatment.
  • The connection between depression and creative genius: does depression enhance artistic abilities?
  • The ethics of using placebo treatment for depression studies.
  • The impact of social and economic inequalities on depression rates.
  • Is depression primarily a mental health issue or a social justice issue?
  • Depression disassembling and treating.
  • Should depression screening be mandatory in the workplace?
  • The influence of gender bias in the diagnosis and treatment of depression.
  • The controversial role of religion and spirituality in managing depression.
  • Is depression a result of individual weakness or societal factors?
  • Abnormal psychology: anxiety and depression case .
  • The link between depression and obesity: examining the bidirectional relationship.
  • The connection between depression and academic performance: causation or correlation?
  • Should depression medication be available over the counter?
  • The impact of internet and social media use on depression rates: harmful or beneficial?
  • Interacting in the workplace: depression.
  • Is depression a modern epidemic or simply better diagnosed and identified?
  • The ethical considerations of using animals in depression research.
  • The effectiveness of psychedelic therapies for treatment-resistant depression.
  • Is depression a disability? The debate on workplace accommodations.
  • Polysubstance abuse among adolescent males with depression.
  • The link between depression and intimate partner violence : exploring the relationship.
  • The controversy surrounding “happy” pills and the pursuit of happiness.
  • Is depression a choice? Examining the role of personal responsibility.

Good Titles for Depression Essays

  • The poetic depictions of depression: exploring its representation in literature.
  • The melancholic symphony: the influence of depression on classical music.
  • Moderate depression symptoms and treatment.
  • Depression in modern music: analyzing its themes and expressions.
  • Cultural perspectives on depression: a comparative analysis of attitudes in different countries.
  • Contrasting cultural views on depression in Eastern and Western societies.
  • Diagnosing depression in the older population.
  • The influence of social media on attitudes and perceptions of depression in global contexts.
  • Countries with progressive approaches to mental health awareness.
  • From taboo to acceptance: the evolution of attitudes towards depression.
  • Depression screening tool in acute settings.
  • The Bell Jar : analyzing Sylvia Plath’s iconic tale of depression .
  • The art of despair: examining Frida Kahlo’s self-portraits as a window into depression.
  • The Catcher in the Rye : Holden Caulfield’s battle with adolescent depression.
  • Music as therapy: how jazz artists turned depression into art.
  • Depression screening tool for a primary care center.
  • The Nordic paradox: high depression rates in Scandinavian countries despite high-quality healthcare.
  • The Stoic East: how Eastern philosophies approach and manage depression.
  • From solitude to solidarity: collective approaches to depression in collectivist cultures.
  • The portrayal of depression in popular culture: a critical analysis of movies and TV shows.
  • The depression screening training in primary care.
  • The impact of social media influencers on depression rates among young adults.
  • The role of music in coping with depression: can specific genres or songs help alleviate depressive symptoms?
  • The representation of depression in literature: a comparative analysis of classic and contemporary works.
  • The use of art as a form of self-expression and therapy for individuals with depression.
  • Depression management guidelines implementation.
  • The role of religion in coping with depression: Christian and Buddhist practices.
  • The representation of depression in the video game Hellblade: Senua’s Sacrifice .
  • The role of nature in coping with depression: can spending time outdoors help alleviate depressive symptoms?
  • The effectiveness of dance/movement therapy in treating depression among older adults.
  • The National Institute for Health: depression management.
  • The portrayal of depression in stand-up comedy: a study of comedians like Maria Bamford and Chris Gethard.
  • The role of spirituality in coping with depression: Islamic and Hindu practices .
  • The portrayal of depression in animated movies : an analysis of Inside Out and The Lion King .
  • The representation of depression by fashion designers like Alexander McQueen and Rick Owens.
  • Depression screening in primary care .
  • The portrayal of depression in documentaries: an analysis of films like The Bridge and Happy Valley .
  • The effectiveness of wilderness therapy in treating depression among adolescents.
  • The connection between creativity and depression: how art can help heal.
  • The role of Buddhist and Taoist practices in coping with depression.
  • Mild depression treatment research funding sources.
  • The portrayal of depression in podcasts: an analysis of the show The Hilarious World of Depression .
  • The effectiveness of drama therapy in treating depression among children and adolescents.
  • The representation of depression in the works of Vincent van Gogh and Edvard Munch.
  • Depression in young people: articles review.
  • The impact of social media on political polarization and its relationship with depression.
  • The role of humor in coping with depression: a study of comedians like Ellen DeGeneres.
  • The portrayal of depression in webcomics: an analysis of the comics Hyperbole and a Half .
  • The effect of social media on mental health stigma and its relationship with depression.
  • Depression and the impact of human services workers.
  • The masked faces: hiding depression in highly individualistic societies.

💭 Depression Speech Topics

Informative speech topics about depression.

  • Different types of depression and their symptoms.
  • The causes of depression: biological, psychological, and environmental factors.
  • How depression and physical issues are connected.
  • The prevalence of depression in different age groups and demographics.
  • The link between depression and anxiety disorders.
  • Physical health: The effects of untreated depression.
  • The role of genetics in predisposing individuals to depression.
  • What you need to know about depression.
  • How necessary is early intervention in treating depression?
  • The effectiveness of medication in treating depression.
  • The role of exercise in managing depressive symptoms.
  • Depression in later life: overview.
  • The relationship between substance abuse and depression.
  • The impact of trauma on depression rates and treatment.
  • The effectiveness of mindfulness meditation in managing depressive symptoms.
  • Enzymes conversion and metabolites in major depression.
  • The benefits and drawbacks of electroconvulsive therapy for severe depression.
  • The effect of gender and cultural norms on depression rates and treatment.
  • The effectiveness of alternative therapies for depression, such as acupuncture and herbal remedies.
  • The importance of self-care in managing depression.
  • Symptoms of anxiety, depression, and peritraumatic dissociation.
  • The role of support systems in managing depression.
  • The effectiveness of cognitive-behavioral therapy in treating depression.
  • The benefits and drawbacks of online therapy for depression.
  • The role of spirituality in managing depression.
  • Depression among minority groups.
  • The benefits and drawbacks of residential treatment for severe depression.
  • What is the relationship between childhood trauma and adult depression?
  • How effective is transcranial magnetic stimulation (TMS) for treatment-resistant depression?
  • The benefits and drawbacks of art therapy for depression.
  • Mood disorder: depression and bipolar.
  • The impact of social media on depression rates.
  • The effectiveness of dialectical behavior therapy (DBT) in treating depression.
  • Depression in older people.
  • The impact of seasonal changes on depression rates and treatment options.
  • The impact of depression on daily life and relationships, and strategies for coping with the condition.
  • The stigma around depression and the importance of seeking help.

Persuasive Speech Topics about Depression

  • How important is it to recognize the signs and symptoms of depression ?
  • How do you support a loved one who is struggling with depression?
  • The importance of mental health education in schools to prevent and manage depression.
  • Social media: the rise of depression and anxiety .
  • Is there a need to increase funding for mental health research to develop better treatments for depression?
  • Addressing depression in minority communities: overcoming barriers and disparities.
  • The benefits of including alternative therapies, such as yoga and meditation, in depression treatment plans.
  • Challenging media portrayals of depression: promoting accurate representations.
  • Two sides of depression disease.
  • How social media affects mental health: the need for responsible use to prevent depression.
  • The importance of early intervention: addressing depression in schools and colleges.
  • The benefits of seeking professional help for depression.
  • There is a need for better access to mental health care, including therapy and medication, for those suffering from depression.
  • Depression in adolescents and suitable interventions.
  • How do you manage depression while in college or university?
  • The role of family and friends in supporting loved ones with depression and encouraging them to seek help.
  • The benefits of mindfulness and meditation for depression.
  • The link between sleep and depression, and how to improve sleep habits.
  • How do you manage depression while working a high-stress job?
  • Approaches to treating depression.
  • How do you manage depression during pregnancy and postpartum?
  • The importance of prioritizing employee mental health and providing resources for managing depression in the workplace.
  • How should you manage depression while caring for a loved one with a chronic illness?
  • How to manage depression while dealing with infertility or pregnancy loss.
  • Andrew Solomon: why we can’t talk about depression.
  • Destigmatizing depression: promoting mental health awareness and understanding.
  • Raising funds for depression research: investing in mental health advances.
  • The power of peer support: establishing peer-led programs for depression.
  • Accessible mental health services: ensuring treatment for all affected by depression.
  • Evidence-based screening for depression in acute care.
  • The benefits of journaling for mental health: putting your thoughts on paper to heal.
  • The power of positivity: changing your mindset to fight depression .
  • The healing power of gratitude in fighting depression.
  • The connection between diet and depression: eating well can improve your mood.
  • Teen depression and suicide in Soto’s The Afterlife .
  • The benefits of therapy for depression: finding professional help to heal.
  • The importance of setting realistic expectations when living with depression.

📝 How to Write about Depression: Essay Structure

We’ve prepared some tips and examples to help you structure your essay and communicate your ideas.

Essay about Depression: Introduction

An introduction is the first paragraph of an essay. It plays a crucial role in engaging the reader, offering the context, and presenting the central theme.

A good introduction typically consists of 3 components:

  • Hook. The hook captures readers’ attention and encourages them to continue reading.
  • Background information. Background information provides context for the essay.
  • Thesis statement. A thesis statement expresses the essay’s primary idea or central argument.

Hook : Depression is a widespread mental illness affecting millions worldwide.

Background information : Depression affects your emotions, thoughts, and behavior. If you suffer from depression, engaging in everyday tasks might become arduous, and life may appear devoid of purpose or joy.

Depression Essay Thesis Statement

A good thesis statement serves as an essay’s road map. It expresses the author’s point of view on the issue in 1 or 2 sentences and presents the main argument.

Thesis statement : The stigma surrounding depression and other mental health conditions can discourage people from seeking help, only worsening their symptoms.

Essays on Depression: Body Paragraphs

The main body of the essay is where you present your arguments. An essay paragraph includes the following:

  • a topic sentence,
  • evidence to back up your claim,
  • explanation of why the point is essential to the argument;
  • a link to the next paragraph.

Topic sentence : Depression is a complex disorder that requires a personalized treatment approach, comprising both medication and therapy.

Evidence : Medication can be prescribed by a healthcare provider or a psychiatrist to relieve the symptoms. Additionally, practical strategies for managing depression encompass building a support system, setting achievable goals, and practicing self-care.

Depression Essay: Conclusion

The conclusion is the last part of your essay. It helps you leave a favorable impression on the reader.

The perfect conclusion includes 3 elements:

  • Rephrased thesis statement.
  • Summary of the main points.
  • Final opinion on the topic.

Rephrased thesis: In conclusion, overcoming depression is challenging because it involves a complex interplay of biological, psychological, and environmental factors that affect an individual’s mental well-being.

Summary: Untreated depression heightens the risk of engaging in harmful behaviors such as substance abuse and can also result in negative thought patterns, diminished self-esteem, and distorted perceptions of reality.

We hope you’ve found our article helpful and learned some new information. If so, feel free to share it with your friends. You can also try our free online topic generator !

  • Pain, anxiety, and depression – Harvard Health | Harvard Health Publishing
  • Depression-related increases and decreases in appetite reveal dissociable patterns of aberrant activity in reward and interoceptive neurocircuitry – PMC | National Library of Medicine
  • How to Get Treatment for Postpartum Depression – The New York Times
  • What Is Background Information and What Purpose Does It Serve? | Indeed.com
  • Thesis | Harvard College Writing Center
  • Topic Sentences: How Do You Write a Great One? | Grammarly Blog

725 Research Proposal Topics & Title Ideas in Education, Psychology, Business, & More

414 proposal essay topics for projects, research, & proposal arguments.

327 Depression Essay Titles & Examples

When choosing a title about depression, you have to remain mindful since this is a sensitive subject. This is why our experts have listed 177 depression essay topics to help you get started.

🌧️ How to Write a Depression Essay: Do’s and Don’ts

🏆 unique titles about depression, 🥇 most interesting depression title ideas, 📌 good titles for depression essay, ✅ simple & easy depression essay titles, 🎓 interesting topics to write about depression, 📑 good research topics about depression.

  • ❓ Research Questions for a Depression Essay

Depression is a disorder characterized by prolonged periods of sadness and loss of interest in life. The symptoms include irritability, insomnia, anxiety, and trouble concentrating. This disorder can produce physical problems, self-esteem issues, and general stress in a person’s life. Difficult life events and trauma are typical causes of depression. Want to find out more? Check out our compilation below.

A depression essay is an important assignment that will help you to explore the subject and its impact on people. Writing this type of paper may seem challenging at first, but there are some secrets that will make achieving a high grade much easier. Check below for a list of do’s and don’ts to get started!

DO select a narrow topic. Before starting writing, define the subject of the paper, and write down some possible titles. This will help you to focus your thoughts instead of offering generic information that can easily be found on Wikipedia. Consider writing about a particular population or about the consequences of depression. For example, a teenage depression essay could earn you excellent marks! If you find this step challenging, try searching for depression essay topics online. This will surely give you some inspiration.

DON’T copy from peers or other students. Today, tutors are usually aware of the power of the Internet and will check your paper for plagiarism. Hence, if you copy information from other depression essays, you could lose a lot of marks. You could search for depression essay titles or sample papers online, but avoid copying any details from these sources.

DO your research before starting. High-quality research is crucial when you write essays on mental health issues. There are plenty of online resources that could help you, including Google Scholar, PubMed, and others. To find relevant scientific articles, search for your primary and secondary topics of interest. Then filter results by relevance, publication date, and access type. This will help you to identify sources that you can view online and use to support your ideas.

DON’T rely on unverified sources. This is a crucial mistake many students make that usually results in failing the paper. Sources that are not academic, such as websites, blogs, and Wiki pages, may contain false or outdated information. Some exceptions are official publications and web pages of medical organizations, such as the CDC, APA, and the World Health Organization.

DO consider related health issues. Depression is often associated with other mental or physical health issues, so you should reflect on this in your paper. Some examples of problems related to depression are suicide, self-harm, eating disorders, and panic attack disorder. To show your in-depth understanding of the issue, you could write a depression and anxiety essay that shows the relationship between the two. Alternatively, you can devote one or two paragraphs to examining the prevalence of other mental health problems in people with depression.

DON’T include personal opinions and experiences unless required. A good essay on the subject of depression should be focused and objective. Hence, you should rely on research rather than on your understanding of the theme. For example, if you have to answer the question “What is depression?” look for scientific articles or official publications that contain the definition rather than trying to explain it in your own words.

DON’T forget about structure. The structure of your essay helps to present arguments or points logically, thus assisting the reader in making sense of the information. A good thing to do is to write a depression essay outline before you start the paper. You should list your key points supported by relevant depression quotes from academic publications. Follow the outline carefully to avoid gaps and inconsistencies.

Use these do’s and don’ts, and you will be able to write an excellent paper on depression! If you want to see more tips and tricks that will help you elevate your writing, look around our website!

  • Understanding Teen Depression Impacts of depression on teenagers Depression is characterized by several effects; however, most of them impact negatively to the teens. For instance, a considerable percentage of teens use extra-curriculum activities such as sports and games, […]
  • Beck Depression Inventory, Its History and Benefits Therefore, the detection of depression at its early stage, the evaluation of the risks, and the definition of the level of depression are the main goals.
  • Health Promotion: Depression Awareness in Teenagers In addition to community sensitization and promoting the expression of melancholic emotions by adolescents, the DAP program will include depression screening days in schools.
  • Report Writing About Depression There is concrete evidence that many people in Australia tend to believe that depression is the cause of all suicide deaths in the world, but this not true.
  • Effect of Social Media on Depression The number of friends that the participants of the mock study had in their social sites was also related to the degree of depression that they experienced.
  • Cognitive Behavioral Therapy in Treating Depression CBT works on the principle that positive thoughts and behaviour heralds positive moods and this is something that can be learned; therefore, by learning to think and behave positively, someone may substitute negative thoughts with […]
  • Anxiety and Depression Among College Students The central hypothesis for this study is that college students have a higher rate of anxiety and depression. Some of the materials to be used in the study will include pencils, papers, and tests.
  • Emotional Wellness: The Issue of Depression Through Different Lenses As for the humanities lens, the increasing prevalence of depression causes the institution of religion to incorporate the issue into major confessions’ mindsets and messages.
  • Depression in the Lens of History and Humanities In terms of history, this paper analyzes the origin of depression and the progress made over the years in finding treatment and preventive mechanisms.
  • Depression, Grief, Loss in “Ordinary People” Film The coach is curious to know Conrad’s experiences at the hospital and the use of ECT. Towards the end of the film, Conrad reveals to the therapist that he feels guilty about his brother’s death.
  • Depression in Older Adults The understanding and modification of the contributions of these factors is the ultimate goal of the clinicians who engage in the treatment of depression.
  • The Problem of Childhood Depression Thus, it is essential to explore the reasons for the disease and possible ways to treat depression in kids. In kids, the prevention of depression is fundamental to understanding the cause of the poor mood […]
  • Depression and Melancholia Expressed by Hamlet The paper will not attempt and sketch the way the signs or symptoms of depression/melancholia play a part in the way Shakespeare’s period or culture concerning depression/melancholia, but in its place portrays the way particular […]
  • Depression in Adolescence and Treatment Approaches The age of adolescence, commonly referred to as children aged 10-19, is characterized by a variety of changes to one’s physical and mental health, as the child undergoes several stages of adjustment to the environment […]
  • Anxiety and Depression: The Case Study As he himself explained, he is not used to positive affirmation due to low self-esteem, and his family experiences also point to the fact that he was not comforted often as a child.
  • Psychological Measures: The Beck Depression Inventory The BDI is used to evaluate levels of depression in patients and to observe the efficacy of other interventions such as antidepressants and electroconvulsive therapy.
  • Organizational Behaviour: Depression in the Workplace This paper will examine the impacts of depression on the employees’ work performance and attendance and look at how managers can deal with hidden depression in such employees. The particular factors that bring about such […]
  • Depression in female adolescents This technique differentiates between those characteristics that are considered normal by the society in relation to female adolescent and those that are peculiar which are symptoms of depression. However, there are side effects related to […]
  • Social Networking and Depression The findings of the study confirmed that once an individual engages in social networking, his or her feeling of safety goes down and depression mood emerges meaning that a correlation between depression and social networking […]
  • The Children’s Depression Inventory (CDI) Measure The author of the article on “Depression in Children: Children’s Depression Inventory” has used both the classical test score and generalizability theories.
  • Using the Neuman Model in the Early Diagnosis of Depression In the history of the academic development of nursing theories, there are a variety of iconic figures who have made significant contributions to the evolution of the discipline: one of them is Betty Neuman.
  • The Beck Depression Contrast (BDI) The second difference between the two modes of the BDI is in the methodology of conducting the survey. This is where the interviewer first gets the history of the patient to try and get the […]
  • Depression and Anxiety Due to School and Work-Related Stress Many young students are not aware of the roots of their psychological problems and continue suffering from depression or anxiety, which results in low productivity, poor achievements, and a decreased quality of life.
  • Depression and Grief in the “Ordinary People” Film At the end of the film, he is healed and ready to forgive his mother and stop blaming himself. I believe that the relationship between Conrad and his therapist, Dr.
  • Beck Depression Inventory: Evaluation Plan Reliability test Pretest and posttest scores from a nonclinical sample of respondents screened a week apart will be compared to determine the reliability of the tool for use in a longitudinal study.
  • Beck Depression Inventory in Psychological Practice Beck in the 1990s, the theory disrupted the traditional flow of Freudian theories development and introduced the audience to the concept of cognitive development, therefore, inviting psychologists to interpret the changes in the patient’s emotional […]
  • Depression Symptoms and Cognitive Behavior Therapy The tone of the article is informative and objective, throughout the text the authors maintain an academic and scientific mood. The structure of the article is well organized and easy to read.
  • Proposal on Depression in Middle-Aged Women By understand the aspect of unhappiness among the young women; it will be easier for the healthcare institutions to formulate effective and appropriate approaches to reduce the menace in the society.
  • Biological Psychology: Lesion Studies and Depression Detection The purpose of this article is to share the research findings and discussion on the new methodological developments of Lesion studies.
  • Using AI to Diagnose and Treat Depression One of the main features of AI is the ability to machine learning, that is, to use data from past experiences to learn and modify algorithms in the future.
  • Artificial Intelligence Bot for Depression By increasing the availability and accessibility of mental health services, these technologies may also contribute to the development of cognitive science practices in Malaysia.
  • COVID-Related Depression: Lingering Signs of Depression The purpose of the article is to depict the research in a more approachable way, while the latter accentuates the importance of various factors and flaws of the results. While the former is more simplified, […]
  • Depression and Anxiety Among African Americans Finally, it should be insightful to understand the attitudes of friends and family members, so 5 additional interviews will be conducted with Black and White persons not having the identified mental conditions. The selected mental […]
  • Depression in Dialysis Patients: Treatment and Management If I were to conduct experimental research about the treatment and management of depression in dialysis patients, I would focus on finding the most effective and safe medication for the condition among adults.
  • The Serotonin Theory of Depression by Moncrieff et al. The serotonin theory of depression is closely related to antidepressants since the advent of SSRIs played a significant role in the popularization of the theory.
  • Avery’s Depression in “The Flick” Play by Baker The emotional and mental state of Avery, the only African-American character out of the three, is fairly obvious from the get-go when asked about why he is so depressed, the answer is: “Um.
  • Depression: A Quantitative-Qualitative Analysis A decision tree can be used due to the nature of the research question or hypothesis in place, the measurement of the dependent or research variable, the number of groups or independent variable levels, and […]
  • Depression Detection Tests Analysis The problem of the abundance of psychological tests leads to the need to compare multiple testing options for indicators of their purpose, features, and interpretations of the evaluation and validity.
  • Nursing Care for Patients With COVID-19 & Depression The significance of the selected problem contributed to the emergence of numerous research works devoted to the issue. This approach to choosing individuals guaranteed the increased credibility of findings and provided the authors with the […]
  • 16 Personality Factors Test for Depression Patient Pablos results, it is necessary to understand the interaction and pattern of the scores of the primary factors. A combination of high Apprehension and high Self-Reliance is a pattern describing a tendency to isolate oneself.
  • Depression in a 30-Year-Old Female Client In the given case, it would be useful to identify the patterns in Alex’s relationships and reconsider her responses to her partner.
  • Depression in Primary Care: Screening and Diagnosis The clinical topics for this research are the incidence of depression in young adults and how to diagnose this disorder early in the primary care setting using screening tools such as PHQ9.
  • Major Depression and Cognitive Behavior Therapy Since the intervention had no significant effect on Lola, the paper will explore the physical health implication of anxiolytics and antidepressants in adolescents, including the teaching strategies that nurses can utilize on consumers to recognize […]
  • Jungian Psychotherapy for Depression and Anxiety They work as a pizza delivery man in their spare time from scientific activities, and their parents also send them a small amount of money every month.S.migrated to New York not only to get an […]
  • COVID-19 and Depression: The Impact of Nursing Care and Technology Nevertheless, combatting depression is a crucial step in posing positive achievements to recover from mental and physical wellness caused by COVID-19.
  • Depression Disorder Intervention The researchers evaluated the socioemotional signs of mental illnesses in a sample of diagnostically referred adolescents with clinical depression required to undergo regular cognitive behavioral therapy in a medical setting.
  • Financial Difficulties in Childhood and Adult Depression in Europe The authors found that the existence of closer ties between the catalyst of depression and the person suffering from depression leads to worse consequences.
  • Activity During Pregnancy and Postpartum Depression Studies have shown that women’s mood and cardiorespiratory fitness improve when they engage in moderate-intensity physical activity in the weeks and months after giving birth to a child.
  • Clinical Depression: Causes and Development Therefore, according to Aaron Beck, the causes and development of depression can be explained through the concepts of schema and negative cognitive triad.
  • Aspects of Working With Depression It also contributes to the maintenance and rooting of a bad mood, as the patient has sad thoughts due to the fact that the usual does not cause satisfaction.
  • Depression Among Nurses in COVID-19 Wards The findings are of great significance to researchers and governments and can indicate the prevalence of anxiety and depression among nurses working in COVID-19 wards in the North-East of England during the pandemic.
  • Depression Associated With Sleep Disorders Y, Chang, C. Consequently, it directly affects the manifestation of obstructive sleep apnea, restless leg syndrome, and periodic limb movement disorder in people with depression.
  • Depression in a 25-Year-Old Male Patient Moreover, a person in depression complains of the slowness in mental processes, notes the oppression of instincts, the loss of the instinct of self-preservation, and the lack of the ability to enjoy life.
  • Aspects and Manifestation of Depression Although, symptoms of depression in young people, in contrast to older adults, are described by psychomotor agitation or lethargy, fatigue, and loss of energy.
  • Complementary Therapy for Postpartum Depression in Primary Care Thus, the woman faced frustration and sadness, preventing her from taking good care of the child, and the lack of support led to the emergence of concerns similar to those in the past.
  • Depression and Anxiety Clinical Case Many of the factors come from the background and life experiences of the patient. The client then had a chance to reflect on the results and think of the possible alternative thoughts.
  • Uncontrolled Type 2 Diabetes and Depression Treatment The data synthesis demonstrates that carefully chosen depression and anxiety treatment is likely to result in better A1C outcomes for the patient on the condition that the treatment is regular and convenient for the patients.
  • Technology to Fight Postpartum Depression in African American Women I would like to introduce the app “Peanut” the social network designed to help and unite women exclusively, as a technology aimed at fighting postpartum depression in African American Women.
  • Complementary Therapy in Treatment of Depression Such practices lower the general level of anxiety and remove the high risks of manifestation of states of abulia, that is, clinical lack of will and acute depression.
  • Social Determinants of Health and Depression Among African American Adults The article “Social Determinants of Health and Depression among African American Adults: A Scoping Review of Current Research” examines the current research on the relationship between social determinants of health and depression among African American […]
  • Outcomes Exercise Has on Depression for People Between 45-55 Years According to the WHO, the rate of depression in the U.S.was 31. 5% as of October 2021, with the majority of the victims being adults aged between 45 and 55 years.
  • The Postpartum Depression in Afro-Americans Policy The distribution of the funds is managed and administered on the state level. Minnesota and Maryland focused on passing the legislation regulating the adoption of Medicaid in 2013.
  • Case Study of Depression and Mental Pressure Alison believes that her illness is severe and taking a toll all the time, and the environment is worsening the condition.
  • Depression Among the Medicare Population in Maryland The statistics about the prevalence and comorbidity rates of depression are provided from the Medicare Chronic Conditions Dashboard and are portrayed in the table included in the paper.
  • Depression as Public Health Population-Based Issue In regard to particular races and ethnicities, CDC provided the following breakdown of female breast cancer cases and deaths: White women: 128 new cases and 20 deaths per 100.
  • Managing Mental Health Medications for Depression and its Ethical Contradiction The second objective is to discover ethical contradictions in such treatment for people of various cultures and how different people perceive the disorder and react to the medication.
  • Aspects of Depression and Obesity In some cases, people with mild to severe depression choose not to seek professional care and instead try to overcome their depression with self-help or the support of family and friends.
  • Antidepressant Treatment of Adolescent Depression At the same time, scientists evidenced that in the case of negative exposure to stress and depression, the human organism diminishes BDNF expression in the hippocampus.
  • Online Peer Support Groups for Depression and Anxiety Disorder The main objective of peer support groups is connecting people with the same life experiences and challenges to share and support each other in healing and recovery.
  • Emotional Encounter With a Patient With Major Depression Disorder I shared this idea with him and was trying to create the treatment plan, sharing some general thoughts on the issue.
  • Childhood Depression in Sub-Saharan Africa According to Sterling et al, depression in early childhood places a significant load on individuals, relatives, and society by increasing hospitalization and fatality and negatively impacting the quality of life during periods of severe depression.
  • Breastfeeding and Risk of Postpartum Depression The primary goal of the research conducted by Islam et al.was to analyze the correlation between exclusive breastfeeding and the risk of postpartum depression among new mothers.
  • Nursing Intervention in Case of Severe Depression The patient was laid off from work and went through a divorce in the year. This led to a change in prescribed medications, and the patient was put on tricyclic anti-depressants.
  • Screening for Depression in Acute Care The literature review provides EB analysis for the topic of depression to identify the need for an appropriate screening tool in addition to the PHQ-9 in the assessment evaluation process.
  • Social Media Use and the Risk of Depression Thapa and Subedi explain that the reason for the development of depressive symptoms is the lack of face to face conversation and the development of perceived isolation. Is there a relationship between social media use […]
  • Depression in the Field of a Healthcare Administrator According to Davey and Harrison, the most challenging part of healthcare administration in terms of depression is the presence of distorted views, shaped by patients’ thoughts.
  • The Treatment of Adolescents With Depression While treating a teenager with depression, it is important to maintain the link between the cause of the mental illness’ progression and the treatment.
  • Depression in the Black Community The speaker said that her counselor was culturally sensitive, which presumes that regardless of the race one belongs to, a specialist must value their background.
  • Loneliness and Depression During COVID-19 While the article discusses the prevalence of loneliness and depression among young people, I agree that young people may be more subject to mental health problems than other population groups, but I do not agree […]
  • Depression Screening in the Acute Setting Hence, it is possible to develop a policy recommending the use of the PHQ-9, such as the EBDST, in the acute setting.
  • Ketamine for Treatment-Resistant Depression: Neurobiology and Applications It is known that a violation of the functions of the serotonergic pathways leads to various mental deviations, the most typical of which is clinical depression.
  • Treating Obesity Co-Occurring With Depression In most cases, the efficiency of obesity treatment is relatively low and commonly leads to the appearance of a comorbid mental health disorder depression.
  • Treadmill Exercise Ameliorates Social Isolation-Induced Depression The groups included: the social isolation group, the control group, and the exercise and social isolation and exercise group. In the treadmill exercise protocol, the rat pups ran on the treadmill once a day for […]
  • Depression and Anxiety Among Chronic Pain Patients The researchers used The Depression Module of the Patient Health Questionnaire and the Generalized Anxiety Disorder Scale to interview participants, evaluate their answers, and conduct the study.
  • The Difference Between Art Deco and Depression Modern Design By and whole, Art Deco and Depression differ in their characteristics and their meanings as they bring unlike messages to the viewers.
  • Postpartum Depression in African American Women As far as African American women are concerned, the issue becomes even more complex due to several reasons: the stigma associated with the mental health of African American women and the mental health complications that […]
  • The Depression Construct and Instrument Analysis For the therapist, this scaling allows to assess the general picture of the patient’s psychological state and obtain a result that is suitable for measurement.
  • The Effects of Cognitive Behavioral Therapy (CBT) on Depression in Adults Introduction It is hard to disagree that there is a vast number of mental disorders that prevent people from leading their normal lives and are quite challenging to treat. One such psychological condition is depression (Li et al., 2020). Since there is a social stigma of depression, and some of its symptoms are similar to […]
  • Stress and Depression Among Nursing Students The study aims to determine how different the manifestations of stress and depression are among American nursing students compared to students of other disciplines and what supports nursing students in continuing their education.
  • Depression in Diabetes Patients The presence of depression concomitant to diabetes mellitus prevents the adaptation of the patient and negatively affects the course of the underlying disease.
  • Depression among Homosexual Males The literature used for the research on the paper aims to overview depression among homosexual males and describe the role of the nurse and practices based on the Recovery Model throughout the depression.
  • “What the Depression Did to People” by Edward Robb Ellis Nevertheless, the way the facts are grouped and delivered could be conducive to students’ ability to develop a clearer picture of the catastrophic downturn’s influences on the nation’s and the poor population’s mentalities.
  • Economic Inequality During COVID-19: Correlation With Depression and Addiction Thus, during the pandemic, people with lower incomes experienced depression and increased their addictive behaviors to cope with the stress of COVID-19.
  • Obesity Co-Occurring With Depression The assessment will identify the patient with the two conditions, address the existing literature on the issue, examine how patients are affected by organizational and governmental policies, and propose strategies to improve the patient experience.
  • Depression in the Black and Minority Ethnic Groups The third sector of the economy includes all non-governmental, non-profit, voluntary, philanthropic, and charitable organizations and social enterprises specializing in various types of activities, which did not find a place in either the public or […]
  • Biological and Social-Cognitive Perspectives on Depression The social-cognitive perspective states that the disorder’s development is influenced by the events in the patient’s life and their way of thinking.
  • A Description on the Topic Screening Depression If there is the implementation of evidence-based care, a reduction in the proportion of disability for patients with depression would be expected. A proposal was written describing the need for screening depression patients of nearly […]
  • “Disclosure of Symptoms of Postnatal Depression, …” by Carolyn Chew-Graham Critique In light of hypothesizing the research question, the researchers suggest that health practitioners have the ability to create a conducive environment for the disclosure of information.
  • Depression – Psychotherapeutic Treatment Taking into account the fact that the specialist is not able to prescribe the medicine or a sort of treatment if he/she is not sure in the positive effect it might have on the health […]
  • Depression as a Major Health Issue The purpose of the study was to examine the implications of cognitive behavior approaches for depression in old women receiving health care in different facilities.
  • Effective Ways to Address Anxiety and Depression Looking deep into the roots of the problem will provide a vast and detailed vision of it, and will help to develop ways to enhance the disorders.
  • Einstepam: The Treatment of Depression The treatment of depression has greatly revolutionized since the development of tricyclic antidepressants and monoamine oxidase inhibitors in the 1950s. In the brain, it inhibits the NMDA receptors and isoforms of NOS.
  • The Potential of Psilocybin in Treating Depression First of all, it is essential to understand the general effects of psilocybin on the brain that are present in the current literature.
  • Depression Among High School Students The major problem surrounding depression among adolescents is that they are rarely diagnosed in time and therefore do not receive treatment they need.
  • NICE Guidelines for Depression Management: Project Proposal This topic is of importance for VEGA because the center does not employ any specific depression management guidelines.
  • Depression: Diagnostics, Prevention and Treatment Constant communication with the patient and their relatives, purposeful questioning of the patient, special scales and tests, active observation of the patient’s appearance and behavior are the steps in the nursing diagnosis of depression.
  • Depression and Anxiety Intervention Plan John’s Wort to intervene for her condition together with the prescribed anti-depressant drugs, I would advise and educate her on the drug-to-drug relations, and the various complications brought about by combining St. Conducting proper patient […]
  • The Use of Psychedelic Drugs in Treating Depression This study aims to establish whether depressive patients can significantly benefit from psilocybin without substantial side effects like in the case of other psychedelic drugs.
  • Postpartum Depression Among the Low-Income U.S. Mothers Mothers who take part in the programs develop skills and knowledge to use the existing social entities to ensure that they protect themselves from the undesirable consequences associated with the PPD and other related psychological […]
  • Depression: Description, Symptoms and Diagnosis, Prognosis and Treatment A diagnosis is made in situations where the symptoms persist for at least two weeks and lead to a change in the individual’s level of functioning.
  • Psychedelic Drugs and Their Effects on Anxiety and Depression The participants must also be willing to remain in the study for the duration of the experiments and consent to the drugs’ use.
  • VEGA Medical Center: The Quality of Depression Management This presentation is going to provide an overview of a project dedicated to the implementation of NICE guidelines at the VEGA Medical Center.
  • Anxiety and Depression in Hispanic Youth in Monmouth County Therefore, the Health Project in Monmouth County will help Hispanic children and adolescents between the ages of 10 and 19 to cope with anxiety and depression through behavioral therapy.
  • Anxiety Disorders and Depression In her case, anxiety made her feel that she needed to do more, and everything needed to be perfect. She noted that the background of her depression and anxiety disorders was her family.
  • Clinical Case Report: Depression It is possible to assume that being in close contact with a person who has depression also increases the probability of experiencing its symptoms.
  • PICO Analysis of Depression In other words, the causes of the given mental disorder can highly vary, and there is no sufficient evidence to point out a primary factor that triggers depression.
  • Interventions for Treating Depression after Stroke Inherently, the link between depression and stroke can be analyzed on the basis of post-stroke depression that is identified as the major neuropsychiatric corollary of stroke.
  • Depression: The Implications and Challenges in Managing the Illness At home, these people lack interest in their family and are not be able to enjoy the shared activities and company of the family.
  • Expression Symptoms of Depression A major finding of the critique is that although the research method and design are appropriate to this type of study, the results may be speculative in their validity and reliability as the researchers used […]
  • Researching Postnatal Depression Health professionals suggest that the fluctuations in the level of hormones cause changes in the chemical composition of the brain. The researcher has stated that the sample was selected from the general practitioners and health […]
  • The Older Women With Depression Living in Long-Term Care The researchers used the probability-sampling method to select the institutions that were included in the study. The health care professionals working in the nursing homes were interviewed to ascertain the diagnosis of depression as well […]
  • Medical Evaluation: 82-Year-Old Patient With Depression Her extreme level of weakness unfolded when the patient admitted that she lacked the strength to stand on her feet and to head back to her sleeping bed on a disastrous night.Mrs.
  • Depression in Adults: Community Health Needs The challenge of depression in the elderly is the recognition of signs and symptoms or the frequent underreporting of the symptoms of depression in adults over the age of 65.
  • The Discussion about Depression in Older Patients Depression is often identified as the most prevalent psychiatric disorder in the elderly and is usually determined by symptoms that belong to somatic, affective, and cognitive categories.
  • Depression in Older People in Australia Although a good number of depressed elderly patients aspire to play an active role in the treatment decision-making process, some prefer to delegate this role to their doctors.
  • In-Vitro Fertilization and Postpartum Depression The research was conducted through based on professional information sources and statistical data collected from the research study used to further validate the evidence and outcome of this study.
  • Depression: Screening and Diagnosis What he tries to do is to live a day and observe the changes that occur around. What do you do to change your attitude to life?
  • Depression in Australia. Evaluation of Different Factors In attempts to identify the biological causes of depression, the researchers focus on the analysis of brain functioning, chemical mediators, their correlations with the neurologic centers in the brain, and impact on the limbic system […]
  • Mental Health Paper: Depression The prevalence of mental health conditions has been the subject of many studies, with most of these highlighting the increase in these illnesses.
  • The Two Hit Model of Cytokine-Induced-Depression The association between IL-6 polymorphism and reduced risk of depressive symptoms confirms the role of the inflammatory response system in the pathophysiology of IFN-alpha-induced depression.
  • Ante-Partum & Postpartum Exposure to Maternal Depression The researchers engaged in the research work on this particular study topic by approaching it on the basis of maternal behavior and circumstances, as they connect to depressive conditions in their own lives and the […]
  • Depression in Australia, How Treat This Disorder According to The World Health Organization, depression is defined as a disorder in the mental health system that is presented with feelings of guiltiness, low concentration, and a decrease in the need for sleep.
  • Steroid Use and Teen Depression In this manner, the researcher will be in a position to determine which of the two indicators is strongest, and then later, the indicators can be narrowed down to the most basic and relevant.
  • Depression Among Minority Groups Mental disorders are among the major problems facing the health sector in America and across the world in the contemporary society.
  • Aspects and Definition of Depression: Psychiatry This is the personal counseling of a patient with the doctor, and it is one of the very best processes. In the case of a physician dealing with a mental patient, the most preferable way […]
  • Alcoholism and Depression: Intervention Strategies The intention of the research paper is to assess if indeed there is an association between alcoholism as manifested by Jackson, and a case of depression.
  • Depression and Paranoid Personality Disorder Bainbridge include: The analysis of paranoia and anxiety caused by substance abuse reveals that the diagnosis can be correct based on the symptoms, but the long-lasting nature of the symptoms rejects this diagnosis in favor […]
  • Antidepressant Drugs for Depression or Dysthymia These are the newer form of antidepressant that are based on both the principle of serotonin reuptake prevention and norepinephrine action.
  • The Relationship of Type 2 Diabetes and Depression Type 2 diabetes is generally recognized as an imbalance between insulin sensitivity and beta cell function We have chosen a rural area in Wisconsin where we can focus our study and select a group of […]
  • Teenage Depression and Alcoholism There also has been a demonstrated connection between alcoholism and depression in all ages; as such, people engage in alcoholism as a method of self medication to dull the feelings of depression, hopelessness and lack […]
  • “Relationships of Problematic Internet Use With Depression”: Study Strengths and Weaknesses One of the study strengths is that the subject selection process is excellently and well-designed, where the subjects represent the study sample, in general.
  • Depression Treatment: Biopsychosocial Theory More to the point, the roles of nurses, an interprofessional team, and the patient’s family will be examined regarding the improvement of Majorie’s health condition.
  • Postpartum Depression and Its Impact on Infants The goal of this research was “to investigate the prevalence of maternal depressive symptoms at 5 and 9 months postpartum in a low-income and predominantly Hispanic sample, and evaluate the impact on infant weight gain, […]
  • Postpartum Depression: Statistics and Methods of Diagnosis The incorporation of the screening tools into the existing electronic medical support system has proved to lead to positive outcomes for both mothers and children.
  • Comorbidity of Depression and Pain It is also known that dysregulation of 5-HT receptors in the brain is directly related to the development of depression and the regulation of the effects of substance P, glutamate, GABA and other pain mediators. […]
  • Depression Among University Students The greatest majority of the affected individuals in different universities will be unable to take good care of their bodies and living rooms.
  • Hallucinations and Geriatric Depression Intervention Sandy has asserted further that the cleaners at the residence have been giving him the wrong medication since they are conspiring to end his life with the FBI.Mr.
  • Changes in Approaches to the Treatment of Depression Over the Past Decade In spite of the fact that over the past decade many approaches to the treatment of depression remained the same, a lot of new methods appeared and replaced some old ones due to the development […]
  • Management of Treatment-Resistant Depression The significance of the problem, the project’s aims, the impact that the project may have on the nursing practice, and the coverage of this condition are the primary focuses of this paper.
  • Teenage Depression: Psychology-Based Treatment This finding underlines the need to interrogate the issue of depression’s ontology and epistemology. Hence, there is the need to have an elaborate and comprehensive policy for addressing teenage depression.
  • Depression and Anxiety in Dialysis Patients However, the study indicates the lack of research behind the connection of depression and cognitive impairment, which is a significant limitation to the conclusive statement.
  • Adolescent Grief and Depression In looking for an activity that may help him or her keep away from the pain he or she is experiencing, the victim may decide to engage in sexual activities. Later, the adolescent is also […]
  • Depression Disorder: Key Factors Epidemiology refers to the study of the distribution and determinants of health related events in specific populations and its applications to health problems.
  • Depression Effects of School Children However the present difficulties that he is going through being a 16 year old; may be associated to a possible cause of Down syndrome complications, or the feelings and behavioral deficiency he associates to the […]
  • Depression, Hallucination, and Suicide: Mental Cases How they handle the process determines the kind of aftermath they will experience for instance it can take the route of hallucinations which is treatable or suicide which is irreversible thus how each case is […]
  • Depression, Its Perspective and Management Therefore this paper seeks to point out that stress is a major ingredient of depression; show the causes, symptoms, highlight how stresses is manifested in different kinds of people, show how to manage stress that […]
  • The Theory of Personality Psychology During Depression The study concerns personality pathology, and the results of the treatment given to patients who are under depression, and how personalities may have adverse effects on the consequences of the cure.
  • Depression and the Media Other components of the cognitive triad of depression are the aspect of seeing the environment as overwhelming and that one is too small to make an impact and also seeing the future as bleak and […]
  • Poor Body Image, Anxiety, and Depression: Women Who Undergo Breast Implants H02: There is no difference in overt attractiveness to, and frequency of intimacy initiated by, the husband or cohabitating partner of a breast implant patient both before and after the procedure.
  • Depression: A Cognitive Perspective Therefore, the cause of depression on this line may be a real shortage of skills, accompanied by negative self-evaluation because the individual is more likely to see the negative aspects or the skills he lacks […]
  • Stress, Depression and Psychoneuroimmunology
  • Depression: Helping Students in the Classroom
  • Family Therapy for Treating Major Depression
  • Adverse Childhood Experiences Cause Depression
  • Rumination, Perfectionism and Depression in Young People
  • Beck’s Cognitive Therapy Approach to Depression Treatment
  • Depression: Risk Factors, Incidence, Preventive Measures & Prognostic Factors
  • Depression Diagnostics Methods
  • Concept Analysis of Loneliness, Depression, Self-esteem
  • Teen Suicide and Depression
  • The Correlation Between Perfectionism and Depression
  • Geriatric Dementia, Delirium, and Depression
  • Dementia, Delirium, and Depression in Older Adults
  • Depression in People With Alcohol Dependence
  • Creating a Comprehensive Psychological Treatment Plan: Depression
  • Experimental Psychology. Bouldering for Treating Depression
  • Depression and Psychotherapy in Adolescence
  • Postpartum Depression: Treatment and Therapy
  • Atypical Depression Symptoms and Treatment
  • Dementia, Delirium, and Depression in Frail Elders
  • Depression & Patient Safety: Speak Up Program
  • Mindfulness Meditation Therapy in Depression Cases
  • A Review of Postpartum Depression and Continued Post Birth Support
  • Psychodynamic Therapy for Depression
  • Depression as a Psychological Disorder
  • Great Depression in “A Worn Path” by Eudora Welty
  • Depression in Adolescents and Interventions
  • Bipolar Disorder: Reoccurring Hypomania & Depression
  • Postpartum Depression: Understanding the Needs of Women
  • Major Depression Treatment During Pregnancy
  • Patients’ Depression and Practitioners’ Suggestions
  • Traditional Symptoms of Depression
  • Social Media Impact on Depression and Eating Disorder
  • Anxiety and Depression in Children and Adolescents
  • Depression Studies and Online Research Sources
  • Depression Explanation in Psychological Theories
  • Depression Assessment Using Intake Notes
  • Depression in Adolescents and Cognitive Therapy
  • Diagnosing Depression: Implementation and Evaluation Plan
  • Depression in Iranian Women and Health Policies
  • Depression Patients and Psychiatrist’s Work
  • Depression Patients’ Needs and Treatment Issues
  • Depression in Patients with Comorbidity
  • Depression After Transcranial Magnetic Stimulation Treatment
  • Depression and Psychosis: 32-Year-Old Female Patient
  • Postpartum Depression and Acute Depressive Symptoms
  • Postpartum Depression and Its Peculiarities
  • Exercises as a Treatment for Depression
  • Depression Treatment Changes in 2006-2017
  • Depression in Elders: Social Factors
  • Depression Among High School Students
  • False Memories in Patients with Depression
  • Postpartum Depression Analysis in “Yellow Wallpaper”
  • The Canadian Depression Causes
  • Teen Website: Fish Will Keep Depression Away
  • Bipolar Expeditions: Mania and Depression
  • Fast Food, Obesity, Depression, and Other Issues
  • Depression in the Future Public Health
  • Depression: Patients With a Difficult Psychological State
  • Depression: Pathophysiology and Treatment
  • Stress, Depression, and Responses to Them
  • Problem of the Depression in Teenagers
  • Supporting the Health Needs of Patients With Parkinson’s, Preeclampsia, and Postpartum Depression
  • Depression and Its Causes in the Modern Society
  • Hamilton Depression Rating Scale Application
  • Yoga for Depression and Anxiety
  • Sleep Disturbance, Depression, Anxiety Correlation
  • Depression in Late Life: Interpersonal Psychotherapy
  • Postpartum Depression and Comorbid Disorders
  • Arab-Americans’ Acculturation and Depression
  • Relationship Between Depression and Sleep Disturbance
  • Child’s Mental Health and Depression in Adulthood
  • Parents’ Depression and Toddler Behaviors
  • Managing Stress and Depression at Work Places – Psychology
  • Job’ Stress and Depression
  • Depression Measurements – Psychology
  • Methodological Bias Associated with Sex Depression
  • Relationship Between Sleep and Depression in Adolescence
  • The Effects of Depression on Physical Activity
  • Psychological Disorder: Depression
  • Depression and Workplace Violence
  • The Effects of Forgiveness Therapy on Depression, Anxiety and Posttraumatic Stress for Women After Spousal Emotional Abuse
  • Depression Diagnosis and Theoretical Models
  • The Impact of Exercise on Women Who Suffer From Depression
  • Evolutionary Psychology: Depression
  • Depression in the Elderly
  • Poly-Substance Abuse in Adolescent Males With Depression
  • How Does Peer Pressure Contribute to Adolescent Depression?
  • How Do Genetic and Environmental Factors Contribute To The Expression of Depression?
  • Depression and Cognitive Therapy
  • Cognitive Treatment of Depression
  • Book Review: “Breadwinning Daughters: Young Women Working in a Depression- Era City, 1929-1939” by Katrina Srigley
  • Depression: A Critical Evaluation
  • Psychopharmacological Treatment for Depression
  • “Breadwinning Daughters: Young Working Women in a Depression-Era City” by Katrina Srigley
  • Interpersonal Communication Strategies Regarding Depression
  • Depression: Law Enforcement Officers and Stress
  • Social Influences on Behavior: Towards Understanding Depression and Alcoholism Based on Social Situations
  • Depression Experiences in Law Enforcement
  • Childhood Depression & Bi-Polar Disorder
  • Depression Psychological Evaluation
  • Concept of Childhood Depression
  • Correlation Between Multiple Pregnancies and Postpartum Depression or Psychosis
  • Depression and Its Effects on Participants’ Performance in the Workplace
  • Catatonic Depression: Etiology and Management
  • Depression: A Cross-Cultural Perspective
  • Depression Levels and Development
  • Depression Treatment: Rational Emotive Behavior Therapy
  • Concept of Depression Disorder
  • Does Divorce Have a Greater Impact on Men than on Women in Terms of Depression?
  • Oral versus Written Administration of the Geriatric Depression Scale

❓Research Questions for a Depression Essay

  • Does Poverty Impact Depression in African American Adolescents and the Development of Suicidal Ideations?
  • Does Neighborhood Violence Lead to Depression Among Caregivers of Children With Asthma?
  • Does Parent Depression Correspond With Child Depression?
  • How Depression Affects Our Lives?
  • Does Brain-Derived Neurotrophic Factor Have an Effect on Depression Levels in Elderly Women?
  • How Can Overcome Depression Through 6 Lifestyle Changes?
  • Does Maternal Depression Have a Negative Effect on Parent-Child Attachment?
  • Can Providers’ Education About Postpartum Depression?
  • Can Vacation Help With Depression?
  • How Children Deal With Depression?
  • Can Diet Help Stop Depression and Violence?
  • Does Depression Assist Eating Disorders?
  • Does Depression Lead to Suicide and Decreased Life Expectancy?
  • Can Obesity Cause Depression?
  • Can Exercise Increase Fitness and Reduce Weight in Patients With Depression?
  • Does Fruit and Vegetable Consumption During Adolescence Predict Adult Depression?
  • Does Depression Cause Cancer?
  • Does Money Relieve Depression?
  • Does the Average Person Experience Depression Throughout Their Life?
  • Are Vaccines Cause Depression?
  • Does Social Anxiety Lead to Depression?
  • Does Stress Cause Depression?
  • How Bipolar and Depression Are Linked?
  • Does Postpartum Depression Affect Employment?
  • Does Postpartum Depression Predict Emotional and Cognitive Difficulties in 11-Year-Olds?
  • Does Regular Exercise Reduce Stress Levels, and Thus Reduce Symptoms of Depression?
  • Does the Natural Light During Winters Really Create Depression?
  • How Can Art Overcome Depression?
  • How Anxiety and Depression Are Connected?
  • Does Positive Psychology Ease Symptoms of Depression?
  • Bullying Research Topics
  • Conflict Research Topics
  • Cognitive Behavioral Therapy Topics
  • Disease Questions
  • Burnout Questions
  • Hyperactivity Disorder Research Ideas
  • Insomnia Questions
  • Eating Disorders Questions
  • Chicago (A-D)
  • Chicago (N-B)

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The Writing Center • University of North Carolina at Chapel Hill

Thesis Statements

What this handout is about.

This handout describes what a thesis statement is, how thesis statements work in your writing, and how you can craft or refine one for your draft.

Introduction

Writing in college often takes the form of persuasion—convincing others that you have an interesting, logical point of view on the subject you are studying. Persuasion is a skill you practice regularly in your daily life. You persuade your roommate to clean up, your parents to let you borrow the car, your friend to vote for your favorite candidate or policy. In college, course assignments often ask you to make a persuasive case in writing. You are asked to convince your reader of your point of view. This form of persuasion, often called academic argument, follows a predictable pattern in writing. After a brief introduction of your topic, you state your point of view on the topic directly and often in one sentence. This sentence is the thesis statement, and it serves as a summary of the argument you’ll make in the rest of your paper.

What is a thesis statement?

A thesis statement:

  • tells the reader how you will interpret the significance of the subject matter under discussion.
  • is a road map for the paper; in other words, it tells the reader what to expect from the rest of the paper.
  • directly answers the question asked of you. A thesis is an interpretation of a question or subject, not the subject itself. The subject, or topic, of an essay might be World War II or Moby Dick; a thesis must then offer a way to understand the war or the novel.
  • makes a claim that others might dispute.
  • is usually a single sentence near the beginning of your paper (most often, at the end of the first paragraph) that presents your argument to the reader. The rest of the paper, the body of the essay, gathers and organizes evidence that will persuade the reader of the logic of your interpretation.

If your assignment asks you to take a position or develop a claim about a subject, you may need to convey that position or claim in a thesis statement near the beginning of your draft. The assignment may not explicitly state that you need a thesis statement because your instructor may assume you will include one. When in doubt, ask your instructor if the assignment requires a thesis statement. When an assignment asks you to analyze, to interpret, to compare and contrast, to demonstrate cause and effect, or to take a stand on an issue, it is likely that you are being asked to develop a thesis and to support it persuasively. (Check out our handout on understanding assignments for more information.)

How do I create a thesis?

A thesis is the result of a lengthy thinking process. Formulating a thesis is not the first thing you do after reading an essay assignment. Before you develop an argument on any topic, you have to collect and organize evidence, look for possible relationships between known facts (such as surprising contrasts or similarities), and think about the significance of these relationships. Once you do this thinking, you will probably have a “working thesis” that presents a basic or main idea and an argument that you think you can support with evidence. Both the argument and your thesis are likely to need adjustment along the way.

Writers use all kinds of techniques to stimulate their thinking and to help them clarify relationships or comprehend the broader significance of a topic and arrive at a thesis statement. For more ideas on how to get started, see our handout on brainstorming .

How do I know if my thesis is strong?

If there’s time, run it by your instructor or make an appointment at the Writing Center to get some feedback. Even if you do not have time to get advice elsewhere, you can do some thesis evaluation of your own. When reviewing your first draft and its working thesis, ask yourself the following :

  • Do I answer the question? Re-reading the question prompt after constructing a working thesis can help you fix an argument that misses the focus of the question. If the prompt isn’t phrased as a question, try to rephrase it. For example, “Discuss the effect of X on Y” can be rephrased as “What is the effect of X on Y?”
  • Have I taken a position that others might challenge or oppose? If your thesis simply states facts that no one would, or even could, disagree with, it’s possible that you are simply providing a summary, rather than making an argument.
  • Is my thesis statement specific enough? Thesis statements that are too vague often do not have a strong argument. If your thesis contains words like “good” or “successful,” see if you could be more specific: why is something “good”; what specifically makes something “successful”?
  • Does my thesis pass the “So what?” test? If a reader’s first response is likely to  be “So what?” then you need to clarify, to forge a relationship, or to connect to a larger issue.
  • Does my essay support my thesis specifically and without wandering? If your thesis and the body of your essay do not seem to go together, one of them has to change. It’s okay to change your working thesis to reflect things you have figured out in the course of writing your paper. Remember, always reassess and revise your writing as necessary.
  • Does my thesis pass the “how and why?” test? If a reader’s first response is “how?” or “why?” your thesis may be too open-ended and lack guidance for the reader. See what you can add to give the reader a better take on your position right from the beginning.

Suppose you are taking a course on contemporary communication, and the instructor hands out the following essay assignment: “Discuss the impact of social media on public awareness.” Looking back at your notes, you might start with this working thesis:

Social media impacts public awareness in both positive and negative ways.

You can use the questions above to help you revise this general statement into a stronger thesis.

  • Do I answer the question? You can analyze this if you rephrase “discuss the impact” as “what is the impact?” This way, you can see that you’ve answered the question only very generally with the vague “positive and negative ways.”
  • Have I taken a position that others might challenge or oppose? Not likely. Only people who maintain that social media has a solely positive or solely negative impact could disagree.
  • Is my thesis statement specific enough? No. What are the positive effects? What are the negative effects?
  • Does my thesis pass the “how and why?” test? No. Why are they positive? How are they positive? What are their causes? Why are they negative? How are they negative? What are their causes?
  • Does my thesis pass the “So what?” test? No. Why should anyone care about the positive and/or negative impact of social media?

After thinking about your answers to these questions, you decide to focus on the one impact you feel strongly about and have strong evidence for:

Because not every voice on social media is reliable, people have become much more critical consumers of information, and thus, more informed voters.

This version is a much stronger thesis! It answers the question, takes a specific position that others can challenge, and it gives a sense of why it matters.

Let’s try another. Suppose your literature professor hands out the following assignment in a class on the American novel: Write an analysis of some aspect of Mark Twain’s novel Huckleberry Finn. “This will be easy,” you think. “I loved Huckleberry Finn!” You grab a pad of paper and write:

Mark Twain’s Huckleberry Finn is a great American novel.

You begin to analyze your thesis:

  • Do I answer the question? No. The prompt asks you to analyze some aspect of the novel. Your working thesis is a statement of general appreciation for the entire novel.

Think about aspects of the novel that are important to its structure or meaning—for example, the role of storytelling, the contrasting scenes between the shore and the river, or the relationships between adults and children. Now you write:

In Huckleberry Finn, Mark Twain develops a contrast between life on the river and life on the shore.
  • Do I answer the question? Yes!
  • Have I taken a position that others might challenge or oppose? Not really. This contrast is well-known and accepted.
  • Is my thesis statement specific enough? It’s getting there–you have highlighted an important aspect of the novel for investigation. However, it’s still not clear what your analysis will reveal.
  • Does my thesis pass the “how and why?” test? Not yet. Compare scenes from the book and see what you discover. Free write, make lists, jot down Huck’s actions and reactions and anything else that seems interesting.
  • Does my thesis pass the “So what?” test? What’s the point of this contrast? What does it signify?”

After examining the evidence and considering your own insights, you write:

Through its contrasting river and shore scenes, Twain’s Huckleberry Finn suggests that to find the true expression of American democratic ideals, one must leave “civilized” society and go back to nature.

This final thesis statement presents an interpretation of a literary work based on an analysis of its content. Of course, for the essay itself to be successful, you must now present evidence from the novel that will convince the reader of your interpretation.

Works consulted

We consulted these works while writing this handout. This is not a comprehensive list of resources on the handout’s topic, and we encourage you to do your own research to find additional publications. Please do not use this list as a model for the format of your own reference list, as it may not match the citation style you are using. For guidance on formatting citations, please see the UNC Libraries citation tutorial . We revise these tips periodically and welcome feedback.

Anson, Chris M., and Robert A. Schwegler. 2010. The Longman Handbook for Writers and Readers , 6th ed. New York: Longman.

Lunsford, Andrea A. 2015. The St. Martin’s Handbook , 8th ed. Boston: Bedford/St Martin’s.

Ramage, John D., John C. Bean, and June Johnson. 2018. The Allyn & Bacon Guide to Writing , 8th ed. New York: Pearson.

Ruszkiewicz, John J., Christy Friend, Daniel Seward, and Maxine Hairston. 2010. The Scott, Foresman Handbook for Writers , 9th ed. Boston: Pearson Education.

You may reproduce it for non-commercial use if you use the entire handout and attribute the source: The Writing Center, University of North Carolina at Chapel Hill

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Home / Essay Samples / Health / Depression / Exploring the Depths of Depression: An Argumentative View

Exploring the Depths of Depression: An Argumentative View

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  • Topic: Depression , Mental Illness , Suicide

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