Importance of Exercise Essay
500 words essay on exercise essay.
Exercise is basically any physical activity that we perform on a repetitive basis for relaxing our body and taking away all the mental stress. It is important to do regular exercise. When you do this on a daily basis, you become fit both physically and mentally. Moreover, not exercising daily can make a person susceptible to different diseases. Thus, just like eating food daily, we must also exercise daily. The importance of exercise essay will throw more light on it.
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Importance of Exercise
Exercising is most essential for proper health and fitness. Moreover, it is essential for every sphere of life. Especially today’s youth need to exercise more than ever. It is because the junk food they consume every day can hamper their quality of life.
If you are not healthy, you cannot lead a happy life and won’t be able to contribute to the expansion of society. Thus, one needs to exercise to beat all these problems. But, it is not just about the youth but also about every member of the society.
These days, physical activities take places in colleges more than often. The professionals are called to the campus for organizing physical exercises. Thus, it is a great opportunity for everyone who wishes to do it.
Just like exercise is important for college kids, it is also essential for office workers. The desk job requires the person to sit at the desk for long hours without breaks. This gives rise to a very unhealthy lifestyle.
They get a limited amount of exercise as they just sit all day then come back home and sleep. Therefore, it is essential to exercise to adopt a healthy lifestyle that can also prevent any damaging diseases .
Benefits of Exercise
Exercise has a lot of benefits in today’s world. First of all, it helps in maintaining your weight. Moreover, it also helps you reduce weight if you are overweight. It is because you burn calories when you exercise.
Further, it helps in developing your muscles. Thus, the rate of your body will increases which helps to burn calories. Moreover, it also helps in improving the oxygen level and blood flow of the body.
When you exercise daily, your brain cells will release frequently. This helps in producing cells in the hippocampus. Moreover, it is the part of the brain which helps to learn and control memory.
The concentration level in your body will improve which will ultimately lower the danger of disease like Alzheimer’s. In addition, you can also reduce the strain on your heart through exercise. Finally, it controls the blood sugar levels of your body so it helps to prevent or delay diabetes.
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Conclusion of Importance of Exercise Essay
In order to live life healthily, it is essential to exercise for mental and physical development. Thus, exercise is important for the overall growth of a person. It is essential to maintain a balance between work, rest and activities. So, make sure to exercise daily.
FAQ of Importance of Exercise Essay
Question 1: What is the importance of exercise?
Answer 1: Exercise helps people lose weight and lower the risk of some diseases. When you exercise daily, you lower the risk of developing some diseases like obesity, type 2 diabetes, high blood pressure and more. It also helps to keep your body at a healthy weight.
Question 2: Why is exercising important for students?
Answer 2: Exercising is important for students because it helps students to enhance their cardiorespiratory fitness and build strong bones and muscles. In addition, it also controls weight and reduces the symptoms of anxiety and depression. Further, it can also reduce the risk of health conditions like heart diseases and more.
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- Importance Of Exercises Essay
Importance of Exercise Essay
500+ words essay on the importance of exercise.
We all know that exercise is extremely important in our daily lives, but we may not know why or what exercise can do. It’s important to remember that we have evolved from nomadic ancestors who spent all their time moving around in search of food and shelter, travelling large distances on a daily basis. Our bodies are designed and have evolved to be regularly active. Over time, people may come across problems if they sit down all day at a desk or in front of the TV and minimise the amount of exercise they do. Exercise is a bodily movement performed in order to develop or maintain physical fitness and good health overall. Exercise leads to the physical exertion of sufficient intensity, duration and frequency to achieve or maintain vigour and health. This essay on the importance of exercise will help students become familiar with the several benefits of doing exercise regularly. They must go through this essay so as to get an idea of how to write essays on similar topics.
Need of Exercise
The human body is like a complex and delicate machine which comprises several small parts. A slight malfunction of one part leads to the breakdown of the machine. In a similar way, if such a situation arises in the human body, it also leads to malfunctioning of the body. Exercise is one of the healthy lifestyles which contributes to optimum health and quality of life. People who exercise regularly can reduce their risk of death. By doing exercise, active people increase their life expectancy by two years compared to inactive people. Regular exercise and good physical fitness enhance the quality of life in many ways. Physical fitness and exercise can help us to look good, feel good, and enjoy life. Moreover, exercise provides an enjoyable way to spend leisure time.
Exercise helps a person develop emotional balance and maintain a strong self-image. As people get older, exercise becomes more important. This is because, after the age of 30, the heart’s blood pumping capacity declines at a rate of about 8 per cent each decade. Exercise is also vital for a child’s overall development. Exercising helps to maintain a healthy weight by stoking our metabolism, utilizing and burning the extra calories.
Types of Exercise
There are three broad intensities of exercise:
1) Light exercise – Going for a walk is an example of light exercise. In this, the exerciser is able to talk while exercising.
2) Moderate exercise – Here, the exerciser feels slightly out of breath during the session. Examples could be walking briskly, cycling moderately or walking up a hill.
3) Vigorous exercise – While performing this exercise, the exerciser is panting during the activity. The exerciser feels his/her body being pushed much nearer its limit compared to the other two intensities. This could include running, cycling fast, and heavy-weight training.
Importance of Exercise
Regular exercise increases our fitness level and physical stamina. It plays a crucial role in the prevention of cardiovascular diseases. It can help with blood lipid abnormalities, diabetes and obesity. Moreover, it can help to reduce blood pressure. Regular exercise substantially reduces the risk of dying of coronary heart disease and eases the risk of stroke and colon cancer. People of all age groups benefit from exercising.
Exercise can be effective in improving the mental well-being of human beings. It relieves human stress and anxiety. When we come back from work or school, we feel exhausted after a whole day of work. If we can go out to have a walk or jog for at least 30 minutes, it makes us feel happy and relaxed. A number of studies have found that a lifestyle that includes exercise helps alleviate depression. Those who can maintain regular exercise will also reduce their chances of seeing a doctor. Without physical activity, the body’s muscles lose their strength, endurance and ability to function properly. Regular exercise keeps all parts of the body in continuous activity. It improves overall health and fitness, as well as decreases the risk of many chronic diseases. Therefore, physical exercise is very important in our life.
Exercise can play a significant role in keeping the individual, society, community and nation wealthy. If the citizens of a country are healthy, the country is sure to touch heights in every facet of life. The country’s healthy generation can achieve the highest marks in various fields and thereby enable their country to win laurels and glory at the international level. The first step is always the hardest. However, if we can overcome it, and exercise for 21 days continuously, it will be a new beginning for a healthy life.
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Frequently Asked Questions on the Importance of Exercises Essay
What are the benefits of exercising regularly.
Regular exercise helps in the relaxation of the mind and body and keeps the body fit. It improves flexibility and blood circulation.
Which are some of the easy exercises that can be done at home?
Sit-ups, bicycle crunches, squats, lunges and planks are examples of easy exercises which can be done at home without the help of costly equipment.
Is cycling an effective form of exercise?
Cycling is a low-impact exercise and acts as a good muscle workout.
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Essay on Importance of Exercise: Benefits for Students
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This article includes an essay on the importance of exercise in 1000 words for school and college class students. Also, explained points like the meaning of exercise, its benefits for students and improvement in life.
Table of Contents
Essay on Importance of Exercise (1000 Words)
School and college students can take help from this article to write paragraphs on the importance of exercise.
What is Exercise?
One must be both physically and mentally fit. Exercising plays an essential role in our lives. It helps us in staying physically meet. Out physical body is meant to maneuver. If we don’t exercise or walk daily, then we’d quickly get susceptible to different diseases overtime.
How will Exercise Improve You?
With exercise, the brain cells are going to be released frequently, which helps in the production of the cells in the hippocampus. Hippocampus is that a part of the brain which helps in learning and controls the memory.
Benefits of Exercise
The recondition and reviving of our full-body is helped by doing exercise. It helps us to form our muscles strong. Exercise also prevents obesity or helps in losing the load. It maintains youthfulness and delays the method of aging.
1. Morning Walk
2. gymnastic exercises.
Under the guidance of an experienced trainer, only one must do gymnastic exercises. Gymnastics could also be positively dangerous to weak constitutions.
4. Free-Hand Exercises
5. aerobics.
Aerobics means using or requiring more oxygen. These exercises are done to form the body to consume more oxygen. Aerobics help to enhance the condition of the cardiovascular system and, therefore, the heart Example: Cycling, Swimming, etc.
6. Anaerobic
7. flexibility.
We should always give proper time to try to exercise because maybe a famous proverb, ”those who don’t have time for exercise will need to find for illness”.
If you have strong muscles and ligaments, you’re having very little chance of joint and lower back pain, as all of your bones are getting to be in proper alignment. The coordination and balance of your body also will get improved.
Importance of Exercises
To achieve life, both mental and physical development is vital. Therefore exercises are essential for the overall growth in one’s life. A balance should be maintained between his work, rest, and activities.
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Importance Of Exercise Essay - 100, 200, 500 Words
- Essay on Importance of Exercise -
It is our responsibility to take care of our bodies and stay fit in order to live a long life. People believe that eating healthy foods is sufficient for the body, ignoring the benefits of exercise. Doctors always advise their patients to make time in their lives to exercise and improve their health. Here are a few sample essays on Importance Of Exercise.
100 Words Essay on Importance of Exercise
200 words essay on importance of exercise, 500 words essay on importance of exercise.
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Keeping our bodies fit enough to live a healthy and wealthy life is one of the most crucial components of existence. Getting up early, eating a nutritious meal, and keeping track of nutrients are all important. Our bodies require exercise as well as nutrients to develop our bones and muscles, boost our mental health, and lose weight. People can avoid orthopedic disorders in their old age by strengthening their bones. Obesity can be avoided by losing weight. People who resist being indolent and prefer to engage in physical activity are more likely to live a pleasant existence. At the end of the day, it is up to the people to change their way of life.
Exercising is one of the most vital processes that everyone should incorporate into their lives. Some people disregard the benefits of physical exercises and how they might help them live a peaceful life. Your body is your responsibility, and the least you can do is stay fit for as long as possible. Exercising not only maintains your body fit, but it also prevents ailments caused by a lack of physical activity. Half of all illnesses can be avoided by engaging in modest exercise on a daily basis . Consider the issue of obesity—obesity is caused mostly by excessive calorie intake and insufficient physical activity. Squats, planks, running, and other exercises can help in the reduction of body weight.
In terms of mental health, exercise has been shown to be a mood booster and aid in the treatment of depression and other mental health issues. This also aids in better sleep at night. Excessive calorie consumption can result in heart disease . Exercise is vital for persons who have long-term cardiac and diabetes problems since it helps them avoid future sickness. Some individuals believe that exercise is only done in a gym and is physically exhausting. However, there are a variety of workouts that can be done from the convenience of your own home.
Physical activity is regarded as one of the most vital components of life , yet many individuals tend to disregard it. Hearing the term "physical activity" drains some people, and they avoid doing it. But many don't realise how beneficial exercise is on its own. It not only helps to keep fit, but it also helps to prevent numerous long-term disorders. It is always preferable for a person to alter their lifestyle in order to do something beneficial to themselves. People must realise how good exercise is, and once they do, they will embark on a healthy lifestyle journey. The following are some of the advantages of exercising that individuals should be aware of—
Reduces Weight
Exercise aids in weight loss and keeping a particular amount of BMI for a healthy lifestyle . A change in diet can only help with calorie reduction; to burn fat, people must step up and conduct regular exercises every day. This activity can also help to lower bad cholesterol in the body and prevent future cardiovascular disease. Excessive physical activity depletes obese persons. They can, however, burn calories without going to the gym every day. Normal daily actions such as walking the stairs frequently, keeping oneself busy, and avoiding binge eating are also ways to lose weight.
Prevents Illness
To avoid pain, the bones and muscles in the body require exercise. Orthopedic experts advise patients to exercise on a daily basis to keep their bones healthy. People who follow a regular fitness plan will never tire quickly.
Some diseases or illnesses, such as stroke, type 2 diabetes, metabolic syndrome, and high blood pressure, can also be avoided with physical activity . While exercising, the brain releases hormones that make individuals joyful, which leads to a reduction in depression. Exercise has always been shown to be good in many aspects, and experts have supported this notion.
Elevates Mood
Exercise is the most effective mood booster. If you are going through a difficult time or need a solution to relieve stress, exercise is the only option. Most people have low self-esteem when it comes to their appearance. This can result in social anxiety and an eating disorder. Regular physical activity alleviates this anxiety . One can gain confidence in themselves and boost their self-esteem. People might also improve their mood by taking a short evening walk to relieve their minds of tension.
Exercise can help improve energy by supplying oxygen and nutrients to the tissues and assisting the circulatory system to function properly. People will have more energy to complete all of their chores this way. People sometimes find it difficult to socialise with others . They see no reason to leave their comfort zone and participate in any enjoyable activity. In this situation, exercise can serve as an excuse for people to socialise. Going to the gym and meeting new people can make your time and day more memorable. Dancing, climbing, backpacking, and athletics are all examples of physical activities that are simple to perform .
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Real-Life Benefits of Exercise and Physical Activity
On this page:
Why is physical activity important?
Emotional benefits of exercise.
Exercise and physical activity are good for just about everyone, including older adults. No matter your health and physical abilities, you can gain a lot by staying active. In fact, studies show that “taking it easy” is risky. Often, inactivity is more to blame than age when older people lose the ability to do things on their own. Lack of physical activity also can lead to more visits to the doctor, more hospitalizations, and more use of medicines for a variety of illnesses.
Including all 4 types of exercise can benefit a wide range of areas of your life. Staying active can help you:
![benefits of exercising essay Four Types of Exercise infographic. Click to open infographic webpage.](https://www.nia.nih.gov/sites/default/files/2023-02/exercise-types-nia_0.png)
- Keep and improve your strength so you can stay independent
- Have more energy to do the things you want to do and reduce fatigue
- Improve your balance and lower risk of falls and injuries from falls
- Manage and prevent some diseases like arthritis, heart disease, stroke, type 2 diabetes, osteoporosis, and 8 types of cancer, including breast and colon cancer
- Sleep better at home
- Reduce levels of stress and anxiety
- Reach or maintain a healthy weight and reduce risk of excessive weight gain
- Control your blood pressure
- Possibly improve or maintain some aspects of cognitive function , such as your ability to shift quickly between tasks or plan an activity
- Perk up your mood and reduce feelings of depression
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Research has shown that exercise is not only good for your physical health, it also supports emotional and mental health. You can exercise with a friend and get the added benefit of emotional support. So, next time you’re feeling down, anxious, or stressed, try to get up and start moving!
Physical activity can help:
- Reduce feelings of depression and stress, while improving your mood and overall emotional well-being
- Increase your energy level
- Improve sleep
- Empower you to feel more in control
In addition, exercise and physical activity may possibly improve or maintain some aspects of cognitive function , such as your ability to shift quickly between tasks, plan an activity, and ignore irrelevant information.
![benefits of exercising essay The Mental Health Benefits of Exercise and Physical Activity infographic. Click to open webpage](https://www.nia.nih.gov/sites/default/files/2023-01/mental-health-exercise-nia_1.jpg)
Here are some exercise ideas to help you lift your mood:
- Walking, bicycling, or dancing. Endurance activities increase your breathing, get your heart pumping, and boost chemicals in your body that may improve mood.
- Yoga. This mind and body practice typically combines physical postures, breathing exercises, and relaxation.
- Tai Chi. This "moving meditation" involves shifting the body slowly, gently, and precisely, while breathing deeply.
- Activities you enjoy. Whether it’s gardening, playing tennis, kicking around a soccer ball with your grandchildren, or something else, choose an activity you want to do, not one you have to do.
You may also be interested in
- Finding tips to help stay motivated to exercise
- Exploring safety tips for exercising outdoors
- Reading about the four types of exercise
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This content is provided by the NIH National Institute on Aging (NIA). NIA scientists and other experts review this content to ensure it is accurate and up to date.
Content reviewed: April 3, 2020
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Physical Activity Is Good for the Mind and the Body
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Health and Well-Being Matter is the monthly blog of the Director of the Office of Disease Prevention and Health Promotion.
Everyone has their own way to “recharge” their sense of well-being — something that makes them feel good physically, emotionally, and spiritually even if they aren’t consciously aware of it. Personally, I know that few things can improve my day as quickly as a walk around the block or even just getting up from my desk and doing some push-ups. A hike through the woods is ideal when I can make it happen. But that’s me. It’s not simply that I enjoy these activities but also that they literally make me feel better and clear my mind.
Mental health and physical health are closely connected. No kidding — what’s good for the body is often good for the mind. Knowing what you can do physically that has this effect for you will change your day and your life.
Physical activity has many well-established mental health benefits. These are published in the Physical Activity Guidelines for Americans and include improved brain health and cognitive function (the ability to think, if you will), a reduced risk of anxiety and depression, and improved sleep and overall quality of life. Although not a cure-all, increasing physical activity directly contributes to improved mental health and better overall health and well-being.
Learning how to routinely manage stress and getting screened for depression are simply good prevention practices. Awareness is especially critical at this time of year when disruptions to healthy habits and choices can be more likely and more jarring. Shorter days and colder temperatures have a way of interrupting routines — as do the holidays, with both their joys and their stresses. When the plentiful sunshine and clear skies of temperate months give way to unpredictable weather, less daylight, and festive gatherings, it may happen unconsciously or seem natural to be distracted from being as physically active. However, that tendency is precisely why it’s so important that we are ever more mindful of our physical and emotional health — and how we can maintain both — during this time of year.
Roughly half of all people in the United States will be diagnosed with a mental health disorder at some point in their lifetime, with anxiety and anxiety disorders being the most common. Major depression, another of the most common mental health disorders, is also a leading cause of disability for middle-aged adults. Compounding all of this, mental health disorders like depression and anxiety can affect people’s ability to take part in health-promoting behaviors, including physical activity. In addition, physical health problems can contribute to mental health problems and make it harder for people to get treatment for mental health disorders.
The COVID-19 pandemic has brought the need to take care of our physical and emotional health to light even more so these past 2 years. Recently, the U.S. Surgeon General highlighted how the pandemic has exacerbated the mental health crisis in youth .
The good news is that even small amounts of physical activity can immediately reduce symptoms of anxiety in adults and older adults. Depression has also shown to be responsive to physical activity. Research suggests that increased physical activity, of any kind, can improve depression symptoms experienced by people across the lifespan. Engaging in regular physical activity has also been shown to reduce the risk of developing depression in children and adults.
Though the seasons and our life circumstances may change, our basic needs do not. Just as we shift from shorts to coats or fresh summer fruits and vegetables to heartier fall food choices, so too must we shift our seasonal approach to how we stay physically active. Some of that is simply adapting to conditions: bundling up for a walk, wearing the appropriate shoes, or playing in the snow with the kids instead of playing soccer in the grass.
Sometimes there’s a bit more creativity involved. Often this means finding ways to simplify activity or make it more accessible. For example, it may not be possible to get to the gym or even take a walk due to weather or any number of reasons. In those instances, other options include adding new types of movement — such as impromptu dance parties at home — or doing a few household chores (yes, it all counts as physical activity).
During the COVID-19 pandemic, I built a makeshift gym in my garage as an alternative to driving back and forth to the gym several miles from home. That has not only saved me time and money but also afforded me the opportunity to get 15 to 45 minutes of muscle-strengthening physical activity in at odd times of the day.
For more ideas on how to get active — on any day — or for help finding the motivation to get started, check out this Move Your Way® video .
The point to remember is that no matter the approach, the Physical Activity Guidelines recommend that adults get at least 150 minutes of moderate-intensity aerobic activity (anything that gets your heart beating faster) each week and at least 2 days per week of muscle-strengthening activity (anything that makes your muscles work harder than usual). Youth need 60 minutes or more of physical activity each day. Preschool-aged children ages 3 to 5 years need to be active throughout the day — with adult caregivers encouraging active play — to enhance growth and development. Striving toward these goals and then continuing to get physical activity, in some shape or form, contributes to better health outcomes both immediately and over the long term.
For youth, sports offer additional avenues to more physical activity and improved mental health. Youth who participate in sports may enjoy psychosocial health benefits beyond the benefits they gain from other forms of leisure-time physical activity. Psychological health benefits include higher levels of perceived competence, confidence, and self-esteem — not to mention the benefits of team building, leadership, and resilience, which are important skills to apply on the field and throughout life. Research has also shown that youth sports participants have a reduced risk of suicide and suicidal thoughts and tendencies. Additionally, team sports participation during adolescence may lead to better mental health outcomes in adulthood (e.g., less anxiety and depression) for people exposed to adverse childhood experiences. In addition to the physical and mental health benefits, sports can be just plain fun.
Physical activity’s implications for significant positive effects on mental health and social well-being are enormous, impacting every facet of life. In fact, because of this national imperative, the presidential executive order that re-established the President’s Council on Sports, Fitness & Nutrition explicitly seeks to “expand national awareness of the importance of mental health as it pertains to physical fitness and nutrition.” While physical activity is not a substitute for mental health treatment when needed and it’s not the answer to certain mental health challenges, it does play a significant role in our emotional and cognitive well-being.
No matter how we choose to be active during the holiday season — or any season — every effort to move counts toward achieving recommended physical activity goals and will have positive impacts on both the mind and the body. Along with preventing diabetes, high blood pressure, obesity, and the additional risks associated with these comorbidities, physical activity’s positive effect on mental health is yet another important reason to be active and Move Your Way .
As for me… I think it’s time for a walk. Happy and healthy holidays, everyone!
Yours in health, Paul
Paul Reed, MD Rear Admiral, U.S. Public Health Service Deputy Assistant Secretary for Health Director, Office of Disease Prevention and Health Promotion
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Benefits of Exercise Essay | Essay on Benefits of Exercise for Students and Children in English
February 13, 2024 by Prasanna
Benefits of Exercise Essay: Obesity and being unhealthy is found in almost every third of children aged two to fifteen. So it’s more important to address this major issue and to get people fit and active.
Exercise helps in the stimulation muscles development, joints and bones, as well as the lungs and heart. It helps a person maintain a constant healthy weight. Exercise helps young people manage symptoms of depression and anxiety.
You can also find more Essay Writing articles on events, persons, sports, technology and many more.
Long and Short Essays on Benefits of Exercise for Students and Kids in English
We are providing students with essay samples on a long essay of 500 words and a short essay of 150 words on the topic of Benefits Of Exercise for reference.
Long Essay on Benefits of Exercise 500 Words in English
Long Essay on Benefits of Exercise is usually given to classes 7, 8, 9, and 10.
We have always heard the word ‘fitness’ and ‘health’. We use it ourselves when we say such phrases like ‘fitness is the key’ and ‘health is wealth’. The word health means the idea of ‘being well’. When a person functions well physically as well as mentally, we call that person healthy and fit.
A healthy lifestyle demands regular exercise, and it is an integral part of being fit. Study after study has shown us the various benefits it can have. Not only does regular exercise help you reduce your risk of developing diseases and manage your weight, but it can also help prevent and treat mental health problems. Exercise is a great way to unwind from the stresses of life and can boost your wellbeing and mood. No matter what one’s age, everyone gets benefitted from regular exercise. To instil healthy habits that may last a lifetime of children, one makes their kids active from an early age. Being active is a huge benefit for older people and seniors.
Exercise helps in the stimulation muscles development, joints and bones, as well as the lungs and heart. It helps children maintain a constant healthy weight. Daily exercise also provides kids with the opportunity to make friends and interact with other people. Exercise helps young people manage symptoms of depression and anxiety.
Compared with previous generations, sedentary lifestyles, jobs, and long commutes have put us more at risk of the dangers of inactivity and unhealthy. Guidelines recommend us to take as much opportunity as we can to do exercise and be active. Every adult should aim at least 150 minutes of moderate-intensity activity over the course of the week. Strengthening exercises are also very important to do at least two days a week. Activities such as exercising with weights or heavy gardening can be included in strengthening exercises. One should aim to do at least some physical activity every day.
There are a whole host of benefits of being as active as possible and reduces one chance of getting several health conditions. Exercising regularly improves your muscular, bone health, cardiorespiratory fitness. It reduces your risk of hypertension or high blood pressure, stroke, coronary heart disease and some cancers. It reduces depression and anxiety and boosts good mental health with good wellbeing and mood.
Whether you have always been active or you’re just starting, make sure you take slow steps to stay, avoid injury and things like a muscle strain. It’s important to drink enough water to keep you hydrated and to eat the right foods to provide the fuel you need to exercise. But a balanced, wholesome diet is the best plan of action for most people.
A person stays happier, being fit and healthy. A healthy and fit person is less prone to chronic diseases. In any pressure situation, a healthy mind reacts better. The self-confidence of a person is increased. Drastic reduction in risk of heart failure. With the increased immunity power helps the body fight against cancerous cells. The intensity of getting a fracture gets decreased with regular exercise.
Short Essay on Benefits of Exercise 150 Words in English
Short Essay on Benefits of Exercise is usually given to classes 1, 2, 3, 4, 5, and 6.
Ahealthy lifestyle demands regular exercise, and it is an integral part of being fit. Study after study has shown us the various benefits it can have. Not only does regular exercise help you reduce your risk of developing diseases and manage your weight, but it can also help prevent and treat mental health problems.
Exercise is a great way to unwind from the stresses of life and can boost your wellbeing and mood. Exercise helps in the stimulation muscles development, joints and bones, as well as the lungs and heart. It helps a person maintain a constant healthy weight. Exercise helps young people manage symptoms of depression and anxiety. A person stays happier, being fit and healthy. A healthy and fit person is less prone to chronic diseases. In any pressure situation, a healthy mind reacts better. The self-confidence of a person is increased. Drastic reduction in risk of heart failure. With the increased immunity power helps the body fight against cancerous cells. The intensity of getting a fracture gets decreased with regular exercise.
10 Lines on Benefits of Exercise in English
- Exercise helps to control and maintain a constant weight by preventing a person from gaining excess weight or maintain weight loss.
- Exercise combats health conditions and diseases.
- Exercise improves wellbeing and mood.
- Exercise boost energy to perform an all-day-long task.
- Exercise promotes better sleep and helps maintain a good sleep cycle.
- Exercise puts the spark back into your sex life.
- Exercise can be fun and interactive and be social!
- Exercises help in the improvement of brain memory and health.
- Exercises can reduce chronic pain.
- Exercise can help skin health.
FAQ’s on Benefits of Exercise Essay
Question 1. Is it good to exercise every day?
Answer: In a well-structured workout program, a weekly day of rest is often advised. As long as you are not getting obsessive about it and not pushing yourself too hard, working out every day is fine.
Question 2. What happens if you don’t exercise?
Answer: If one does less exercise or activity will become deconditioned. Your lose bulk and weakens including muscle strain. Your muscle needs breathing especially the large muscles in legs and arms. The more breathless you become, the less activity you do.
Question 3. Which exercise burns the most fat?
Answer: High-Intensity Interval Training is one of the most effective ways to burn body fat. HIIT is an intense aerobic method that includes Tabata-styled or sprinting workout designed to condition the body in less time than steady-state low-intensity cardio.
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- v.8(7); 2018 Jul
Health Benefits of Exercise
Gregory n. ruegsegger.
1 Department of Biomedical Sciences, University of Missouri, Columbia, Missouri 65211
Frank W. Booth
2 Department of Medical Pharmacology and Physiology, University of Missouri, Columbia, Missouri 65211
3 Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, Missouri 65211
4 Dalton Cardiovascular Research Center, University of Missouri, Columbia, Missouri 65211
Overwhelming evidence exists that lifelong exercise is associated with a longer health span, delaying the onset of 40 chronic conditions/diseases. What is beginning to be learned is the molecular mechanisms by which exercise sustains and improves quality of life. The current review begins with two short considerations. The first short presentation concerns the effects of endurance exercise training on cardiovascular fitness, and how it relates to improved health outcomes. The second short section contemplates emerging molecular connections from endurance training to mental health. Finally, approximately half of the remaining review concentrates on the relationships between type 2 diabetes, mitochondria, and endurance training. It is now clear that physical training is complex biology, invoking polygenic interactions within cells, tissues/organs, systems, with remarkable cross talk occurring among the former list.
The aim of this introduction is briefly to document facts that health benefits of physical activity predate its readers. In the 5th century BC, the ancient physician Hippocrates stated: “All parts of the body, if used in moderation and exercised in labors to which each is accustomed, become thereby healthy and well developed and age slowly; but if they are unused and left idle, they become liable to disease, defective in growth and age quickly.” However, by the 21st century, the belief in the value of exercise for health has faded so considerably, the lack of exercise now presents a major public health problem ( Fig. 1 ) ( Booth et al. 2012 ). Similarly, the lack of exercise was classified as an actual cause of chronic diseases and death ( Mokdad et al. 2004 ).
![Click on image to zoom An external file that holds a picture, illustration, etc.
Object name is cshperspectmed-BEX-029694_F1.jpg](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027933/bin/cshperspectmed-BEX-029694_F1.jpg)
Simplistic overview of how physical activity can prevent the development of type 2 diabetes and one of its complications, cardiovascular disease. Physical inactivity is an actual cause of type 2 diabetes, cardiovascular disease, and tens of other chronic conditions ( Table 1 ) via interaction with other factors (e.g., age, diet, gender, and genetics) to increase disease risk factors. This leads to chronic disease, reduced quality of life, and premature death. However, physical activity can prevent and, in some cases, treat disease progression associated with physical inactivity and other genetic and environmental factors.
Published in 1953, Jeremy N. Morris and colleagues conducted the first rigorous epidemiological study investigating physical activity and chronic disease risk, in which coronary heart disease (CHD) rates were increased in physically inactive bus drivers versus active conductors ( Morris et al. 1953 ). Since this pioneering report, a plethora of evidence shows that physical inactivity is associated with the development of 40 chronic diseases ( Table 1 ), including major noncommunicable diseases such as type 2 diabetes (T2D) and CHD, and as premature mortality ( Booth et al. 2012 ).
Worsening of 40 conditions caused by the lack of physical activity with growth, maturation, and aging throughout life span
1. Accelerated biological aging/premature death |
2. Aerobic (cardiorespiratory) fitness (VO ) |
3. Arterial dyslipidemia |
4. Balance |
5. Bone fracture/falls |
6. Breast cancer |
7. Cognitive dysfunction |
8. Colon cancer |
9. Congestive heart failure |
10. Constipation |
11. Coronary (ischemic) heart disease |
12. Deep vein thrombosis |
13. Depression and anxiety |
14. Diverticulitis |
15. Endometrial cancer |
16. Endothelial dysfunction |
17. Erectile dysfunction |
18. Gallbladder diseases |
19. Gestational diabetes |
20. Hemostasis |
21. Hypertension |
22. Immunity |
23. Insulin resistance |
24. Large arteries lose more compliance with aging |
25. Metabolic syndrome |
26. Nonalcoholic fatty liver disease |
27. Obesity |
28. Osteoarthritis |
29. Osteoporosis |
30. Ovarian cancer |
31. Pain |
32. Peripheral artery disease |
33. Preeclampsia |
34. Polycystic ovary syndrome |
35. Prediabetes |
36. Rheumatoid arthritis |
37. Sarcopenia |
38. Stroke |
39. Tendons being less stiff |
40. Type 2 diabetes |
The breadth of the list implies that a single molecular target will not substitute for appropriate daily physical activity to prevent the loss of all listed items.
In this review, we highlight the far-reaching health benefits of physical activity. However, note that the studies cited here represent only a fraction of the >100,000 studies showing positive associations between the terms “exercise” and “health.” In addition, we discuss how exercise promotes complex integrative responses that lead to multisystem responses to exercise, an underappreciated area of medical research. Finally, we consider how strategies that “mimic” parts of exercise training compare with physical exercise for their potential to combat metabolic disease.
EXERCISE IMPROVES CARDIORESPIRATORY FITNESS
There is arguably no measure more important for health than cardiorespiratory fitness (CRF) (commonly measured by maximal oxygen uptake, VO 2max ) ( Blair et al. 1989 ). For example, Myers et al. (2002 ) showed that each 1 metabolic equivalent (1 MET) increase in exercise-test performance conferred a 12% improvement in survival, stating that “VO 2max is a more powerful predictor of mortality among men than other established risk factors for cardiovascular disease (CVD).” Low CRF is also well established as an independent risk factor of T2D ( Booth et al. 2002 ) and CVD morbidity and mortality ( Kodama et al. 2009 ; Gupta et al. 2011 ). Similarly, Kokkinos et al. (2010) reported that men who transitioned from having low to high CRF decreased their mortality risk by ∼50% over an 8-yr period, whereas men who transitioned from having high to low CRF increased their mortality risk by ∼50%.
Importantly then, from the above paragraph, physical activity and inactivity are major environmental modulators of CRF, increasing and decreasing it, respectively, often through independent pathways. Findings from rats selectively bred for high or low intrinsic aerobic capacity show that rats bred for high capacity, which are also more physically active, have 28%–42% increases in life span compared to low-capacity rats ( Koch et al. 2011 ). Endurance exercise is well recognized to improve CRF and cardiometabolic risk factors. Exercise improves numerous factors speculated to limit VO 2max including, but not restricted to, the capacity to transport oxygen (e.g., cardiac output), oxygen diffusion to working muscles (e.g., capillary density, membrane permeability, muscle myoglobin content), and adenosine triphosphate (ATP) generation (e.g., mitochondrial density, protein concentrations).
Data from the HERITAGE Family Study has provided some of the first knowledge of genes associated with VO 2max plasticity because of endurance-exercise training. Following 6 wk of cycling training at 70% of pretraining VO 2max , Timmons et al. (2010) performed messenger RNA (mRNA) expression microarray profiling to identify molecules potentially predicting VO 2max training responses, and then assessed these molecular predictors to determine whether DNA variants in these genes correlated with VO 2max training responses. This approach identified 29 mRNAs in skeletal muscle and 11 single-nucleotide polymorphisms (SNPs) that predicted ∼50% and ∼23%, respectively, of the variability in VO 2max plasticity following aerobic training ( Timmons et al. 2010 ). Intriguingly, pretraining levels of these mRNAs were greater in subjects that achieved greater increases in VO 2max following aerobic training, and of the 29 mRNAs, >90% were unchanged with aerobic training, suggesting that alternative exercise intervention paradigms or pharmacological strategies may be needed to improve VO 2max in individuals with a low responder profile for the identified predictor genes ( Timmons et al. 2010 ). Keller et al. (2011) found that, in response to endurance training, improvements in VO 2max were associated with effectively up-regulating proangiogenic gene networks and miRNAs influencing the transcription factor–directed networks for runt-related transcription factor 1 (RUNX1), paired box gene 3 (PAC3), and sex-determining region Y box 9 (SOX9). Collectively, these results led the investigators to speculate that improvements in skeletal muscle oxygen sensing and angiogenesis are primary determinates in training responses in VO 2max ( Keller et al. 2011 ).
Clinically important concepts have emerged from the pioneering HERITAGE Family Study. One new clinical concept is that a threshold dose–response relationship influences the percentage of subjects responding with an increase in VO 2max to endurance training volumes (with volume being defined here as the product of intensity × duration), as previously published ( Slentz et al. 2005 , 2007 ). Ross et al. (2015) later extended the aforementioned Slentz et al. studies. After a 24-wk-long endurance training study ( Ross et al. 2015 ), percentages of women and men identified as nonresponders to the training (i.e., defined as not increasing their VO 2peak ) progressively fell inversely to a two stepwise progressive increase in endurance-exercise training volume, as described next. Thirty-nine percent (15 of 39) of training subjects did not increase their VO 2peak in response to the low-amount, low-intensity training; 18% (9 of 51) had no increase in VO 2peak in the group having high-amount, low-intensity training; and 0% (0 of 31) who underwent high-amount, high-intensity training did not increase their VO 2peak . A biological basis for the dose–response relationship in the previous sentence could be made from an analysis of interval training (IT) and IT/continuous-training studies published from 1965 to 2012 ( Bacon et al. 2013 ). A second older concept is being reinvigorated; Bacon et al. (2013) indicate that different endurance-exercise intensities and durations are needed for different systems in the body. They suggest that very short periods of high-intensity endurance-type exercise may be needed to reach a threshold for peripheral metabolic adaptations, but that longer training durations at lower intensities are required to see large changes in maximal cardiac output and VO 2max .
A comparable example exists for resistance training. Maximal resistance loads require a minimum of 2 min/per wk for each muscle group recruited by a specific maneuver to obtain a strength training adaptation [(8 contractions/set × 2 sec/contraction × 3 sets/day) × 2 days/wk) = 96 sec]. As of 2016, one opinion from Sarzynski et al. (2016) for the molecular mechanisms by which endurance exercise drives VO 2max include, but are not limited to, calcium signaling, energy sensing and partitioning, mitochondrial biogenesis, angiogenesis, immune functions, and regulation of autophagy and apoptosis.
Perhaps more importantly, lifelong aerobic exercise training preserves VO 2max into old age. CRF generally increases until early adulthood, then declines the remainder of life in sedentary humans ( Astrand 1956 ). The age-related decline in VO 2max is not trivial, as Schneider (2013) reported a ∼40% decline in healthy males and females spanning from 20 to 70 yr of age. However, cross-sectional data show that with lifelong aerobic exercise training, trained individuals often have the same VO 2max as a sedentary individual four decades younger ( Booth et al. 2012 ). Myers et al. (2002) found that low estimated VO 2max increases mortality 4.5-fold compared to high estimated VO 2max . They concluded, “Exercise capacity is a more powerful predictor of mortality among men than other established risk factors for cardiovascular disease.” Given the strong association between CRF, chronic disease, and mortality, we feel identifying the molecular transducers that cause age-related reductions in CRF may have profound implications for improving health span and delaying the onset of chronic disease. In two of our recent papers, transcriptomics was performed on the triceps muscle ( Toedebusch et al. 2016 ) and on the cardiac left ventricle ( Ruegsegger et al. 2017 ). We were addressing the question of what molecule initiates the beginning of the lifelong decline in aerobic capacity with aging. Aerobic capacity (VO 2max ) involves, at a minimum, the next systems/tissues, as oxygen travels through the mouth, airways, pulmonary membrane, pulmonary circulation, left heart, aorta/arteries/capillaries, and sarcoplasm/myoglobin to mitochondria. We allowed female rats access, or no access, to running wheels from 5 to 27 wk of age. Surprisingly, voluntary running had no effect on the delay in the beginning of the lifetime decrease in VO 2max . Our skeletal muscle transcriptomics elicited no molecular targets, whereas gene networks suggestive of influencing maximal stroke volume were identified in the left ventricle transcriptomics ( Ruegsegger et al. 2017 ).
Publications concerning the effects of exercise on the brain (from 54 to 216 papers listed on PubMed from 2007 to 2016) have increased 400%. In addition, a 2016 study ( Schuch et al. 2016 ) of three previous papers reported that humans with low- and moderate-CRF had 76% and 23%, respectively, increased risk of developing depression compared to high CRF in three publications. With this forming trend, the next section will consider exercise and brain health.
EXERCISE IMPROVES MENTAL HEALTH
Many studies support physical activity as a noninvasive therapy for mental health improvements in cognition ( Beier et al. 2014 ; Bielak et al. 2014 ; Tian et al. 2014 ), depression ( Kratz et al. 2014 ; McKercher et al. 2014 ; Mura et al. 2014 ), anxiety ( Greenwood et al. 2012 ; Nishijima et al. 2013 ; Schoenfeld et al. 2013 ), neurodegenerative diseases (i.e., Alzheimer’s and Parkinson’s disease) ( Bjerring and Arendt-Nielsen 1990 ; Mattson 2014 ), and drug addiction ( Zlebnik et al. 2012 ; Lynch et al. 2013 ; Peterson et al. 2014 ). In 1999, van Praag et al. (1999) showed the survival of newborn cells in the adult mouse dentate gyrus, a hippocampal region important for spatial recognition, is enhanced by voluntary wheel running. Similarly, spatial pattern separation and neurogenesis in the dentate gyrus are strongly correlated in 3-mo-old mice following 10 wk of voluntary wheel running ( Creer et al. 2010 ), and the development of new neurons in the dentate gyrus is coupled with the formation of new blood vessels ( Pereira et al. 2007 ). Many exercise-related improvements in cognitive function have been associated with local and systemic expression of growth factors in the hippocampus, notably, brain-derived neurotrophic factor (BDNF) ( Neeper et al. 1995 ; Cotman and Berchtold 2002 ). BDNF promotes many developmental functions in the brain, including neuronal cell survival, differentiation, migration, dendritic arborization, and synaptic plasticity ( Park and Poo 2013 ). In rat hippocampus, regular exercise promotes a progressive increase in BDNF protein for up to at least 3 mo ( Berchtold et al. 2005 ). In an opposite manner, BDNF mRNA in the hippocampus is rapidly decreased by the cessation of wheel running, suggesting BDNF expression is tightly related to exercise volume ( Widenfalk et al. 1999 ).
Findings by Wrann et al. (2013) highlight one mechanism by which endurance exercise may up-regulate BDNF expression. To summarize, Wrann et al. (2013) noted that exercise increases the activity of the estrogen-related receptor α (ERRα)/peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) complex, in turn increasing levels of the exercise-secreted factor FNDC5 in skeletal muscle and the hippocampus, whose cleavage products provide beneficial effects in the hippocampus by increasing BDNF gene expression. While future research should determine whether the FNDC5 cleavage-product was produced locally in hippocampal neurons or was secreted into the circulation, this finding eloquently displays one mechanism responsible for brain health benefits following exercise. Similarly, work by van Praag and colleagues suggests that exercise or pharmacological activation of AMP-activated protein kinase (AMPK) in skeletal muscle enhances indices of learning and memory, neurogenesis, and gene expression related to mitochondrial function in the hippocampus ( Kobilo et al. 2011 , 2014 ; Guerrieri and van Praag 2015 ).
Insulin-like growth factor 1 (IGF-1), is central to many exercise-induced adaptations in the brain. Like BDNF, physical activity increases circulatory IGF-1 levels and both exercise and infusion of IGF-1 increase BrdU + cell number and survivability in the hippocampus ( Trejo et al. 2001 ). Similarly, the protective effects of exercise on various brain lesions are nullified by anti-IGF-1 antibody ( Carro et al. 2001 ).
In 1979, Greist et al. (1979) provided evidence that running reduced depression symptoms similarly to psychotherapy. However, the precise mechanisms by which exercise prevents and/or treats depression remain largely unknown. Of the proposed mechanisms, increases in the availability of brain neurotransmitters and neurotrophic factors (e.g., BDNF, dopamine, glutamate, norepinephrine, serotonin) are perhaps the best studied. For example, tyrosine hydroxylase (TH) activity, the rate-limiting enzyme in dopamine formation, in the striatum, an area of the brain's reward system, is increased following 7 days of treadmill running in an intensity-dependent manner ( Hattori et al. 1994 ). Voluntary wheel running is also highly rewarding in rats, and voluntary wheel running in rats lowers the motivation to self-administer cocaine, suggesting exercise may be a viable strategy in the fight against drug addiction ( Larson and Carroll 2005 ).
Similar to the above examples, secreted factors from skeletal muscle have been linked to the regulation of depression. Agudelo et al. (2014) showed that exercise training in mice and humans, and overexpression of skeletal muscle PGC-1α1, leads to robust increases in kynurenine amino transferase (KAT) expression in skeletal muscle, an enzyme whose activity protects from stress-induced increases in depression in the brain by converting kynurenine into kynurenic acid. Additionally, overexpression of PGC-1α1 in skeletal muscle left mice resistant to stress, as evaluated by various behavioral assays indicative of depression ( Agudelo et al. 2014 ). Simultaneously, they report gene expression related to synaptic plasticity in the hippocampus, such as BDNF and CamkII, were unaffected by chronic mild stress compared to wild-type mice. Collectively, these findings suggest exercise-induced increases in skeletal muscle PGC-1α1 may be an important regulator of KAT expression in skeletal muscle, which, via modulation in plasma kynurenine levels, may alleviate stress-induced depression and promote hippocampal neuronal plasticity.
TYPE 2 DIABETES, MITOCHONDRIA, AND EXERCISE
T2d predictions show a pandemic.
In a 2001 Diabetes Care article ( Boyle et al. 2001 ), investigators at the U.S. Centers for Disease Control (CDC) predicted 29 million U.S. cases of T2D would be present in 2050. Unfortunately, the 2001 prediction of 29 million was reached in 2012! For 2012, the American Diabetes Association reported that 29 million Americans had diagnosed and undiagnosed T2D, which was 9% of the American population ( Dwyer-Lindgren et al. 2016 ). More rapid increases in T2D are now predicted by the CDC than in the previous estimate. The CDC now predicts a doubling or tripling in T2D in 2050. The tripling would mean that one out of three U.S. adults would have T2D in their lifetime by 2050 ( Boyle et al. 2010 ), which would be >100 million U.S. cases. The International Diabetes Federation (IDF) reports T2D cases worldwide. In 2015, the IDF reported that 344 and 416 million North American (including Caribbean) and worldwide adults, respectively, had T2D. Furthermore, the IDF predicts for 2040 that 413 and 642 million, respectively, will have T2D. In sum, T2D is now pandemic, and the pandemic will increase in numbers without current apparent action within the general public.
Type 2 Diabetes Prevalence Is Based on a Strong Genetic Predisposition
The Framingham study found that T2D risk in offspring was 3.5-fold and sixfold higher for a single and two diabetic parent(s), respectively, as compared to nondiabetic offspring ( Meigs et al. 2000 ). Thus, T2D is gene-based.
Noncoding regions of the human genome contain >90% of the >100 variants associated with both T2D and related traits that were observed in genome-wide association studies ( Scott et al. 2016 ). Another 2016 paper ( Kwak and Park 2016 ) lists at least 75 independent genetic loci that are associated with T2D. Taken together, T2D is a complex genetic disease ( Scott et al. 2016 ).
Type 2 Diabetes Is Modulated by Lifestyle, with Exercise as the More Powerful Lifestyle Factor
Three large-scale epidemiological studies have been performed on prediabetics, each in a different geographical location. The first study, and only study to have separate study arms for diet and exercise, was in China. The pure exercise intervention group had a 46% reduction in the onset of T2D, relative to the nontreated group, after 6 yr of the study ( Pan et al. 1997 ). Diet alone reduced T2D by 31% in the Chinese study. The second study on T2D was the Finnish Diabetes Prevention Study. It found a 58% reduction in T2D in the lifestyle intervention (combined diet and exercise) in its 522 prediabetic subjects after a mean study duration of 3.2 yr ( Tuomilehto et al. 2001 ). The latest of the three studies was in the U.S. Diabetes Prevention Program. The large randomized trial ( n = 3150 prediabetics) was stopped after 2.8 yr, because of harm to the control group. T2D prevalence in the high-risk adults was reduced by 58% with intensive lifestyle (diet and exercise) intervention, whereas the drug arm (metformin) of the study only reduced T2D by 31%, both compared to the noninnervation group ( Knowler et al. 2002 ). Thus, if differences in genetics in the above three differing ethnicities are not a factor, combined exercise and diet remain more effective in T2D prevention than the drug metformin two decades ago.
Exercise Increases Glucose by Signaling Independent of the Insulin Receptor
A single exercise bout increases glucose uptake by skeletal muscle, sidestepping the insulin receptor and thus insulin resistance in T2D patients ( Holloszy and Narahara 1965 ; Goodyear and Kahn 1998 ; Holloszy 2005 ). After insulin binding to its receptor, insulin initiates a downstream signaling cascade of tyrosine autophosphorylation of insulin receptor, insulin receptor substrate 1 (IRS-1) binding and phosphorylation, activation of a PI3K-dependent pathway, including key downstream regulators protein kinase B (Akt) and the Akt substrate of 160 kDa (AS160), ultimately promoting glucose transporter 4 (GLUT4) translocation to the plasma membrane ( Rockl et al. 2008 ; Stanford and Goodyear 2014 ). Despite normal GLUT4 levels, insulin fails to induce GLUT4 translocation in T2D ( Zierath et al. 2000 ). However, exercise activates a downstream insulin-signaling pathway at AS160 and TBC1 domain family member 1 (TBC1D1) ( Deshmukh et al. 2006 ; Maarbjerg et al. 2011 ), facilitating GLUT4 expression translocation to the plasma membrane independent of the insulin receptor. We contend that exercise could be considered as a very powerful tool to primarily attenuate the T2D pandemic.
Complex Biology of T2D Interactions with the Complex Biology of Exercise
An important consideration from the above is that T2D is such a genetically complex disease that a single gene has not been proven to be sufficiently causal to be effective, at this stage in time, to be a successful target for pharmacological treatment. The expectation for a single molecule target has been met for infectious diseases, which are often monogenic diseases. For example, a vaccine against smallpox was highly successful. Edward Jenner in 1796 produced the first successful vaccine. An important fact is that exercise is genetically complex. The literature allows us to speculate that exercise is at least as genetically complex as the approximately 75 genes associated with T2D ( Kwak and Park 2016 ). An example indicating that exercise is complex biology follows. RNA sequencing analysis of all 119 vastus lateralis muscle biopsies found that endurance training for 4 days/wk for 12 wk produced the differential expression of 3404 putative isoforms, belonging to 2624 different genes, many associated with oxidative ATP production in 23 women and men aged 29 yr old ( Lindholm et al. 2016 ). Our notion is that over 2600 genes suggests complex biology.
A “Case-Type” Study of the Molecular Underpinnings of Exercise, Mitochondria, and T2D Interactions
A PubMed search for the terms “diabetes mitochondria exercise molecular” elicited 74 papers. We arbitrarily selected some of the most recent 50 (spanning from mid-2014 into January 2017), with the assumption they would be representative of any other papers that we did not find in our search. Papers fell into our two arbitrary categories of single gene studies versus “omic”-type studies. First, subcategories of studies that develop themes will be arbitrarily presented.
Recent Studies Show Single Gene Manipulation Alters Mitochondrial Level and Running Performance
Numerous reports in the past couple of years observed that single gene manipulations increase mitochondrial gene expression and activity, which was also associated with increased exercise performance/capacity. A few of these are presented below:
- Irisin was shown to increase oxidative metabolism in myocytes and increase PGC-1α mRNA and protein ( Vaughan et al. 2014 ), which extends the first observation made earlier in adipose tissue by Spiegelman ( Bostrom et al. 2012 ).
- Patients with impaired glucose tolerance underwent low-intensity exercise training. Patients whose mitochondrial markers increased to levels that were measured in a separate cohort of nonexercised healthy individuals recovered normal glucose tolerance ( Osler et al. 2015 ). In opposition, those patients whose mitochondria markers did not improve, remained with impaired glucose tolerance.
- In 2003, muscle PGC-1α mRNA was shown to be induced by endurance-exercise training in human skeletal muscle ( Short et al. 2003 ). PGC-1α was shown to have multiple isoforms ( Lin et al. 2002 ). After a 60-min cycling bout, human vastus lateralis biopsies were taken from both sexes in their mid-20s. Additional biopsies were taken 30 min, and at 2, 6, and 24 hr postexercise. At 30 min postexercise, PGC-1α-ex1b mRNA and PGC-1α mRNA increased 468- and 2.4-fold, respectively, whereas PGC-1α-ex1b protein and PGC-1α protein increased 3.1-fold and no change, respectively. Gidlund et al. (2015 ) interprets the above data as implying PGC-1α-ex1b could be responsible for other changes that have previously been recorded before the increase in total PGC-1α postexercise.
- Mice with knockout of the kinin B1 receptor gene had higher mitochondrial DNA quantification and of mRNA levels of genes related to mitochondrial biogenesis in soleus and gastrocnemius muscles and had higher exercise times to exhaustion, but did not have higher VO 2max ( Reis et al. 2015 ).
- Mice do not normally express cholesteryl ester transfer protein (CETP), which is a lipid transfer protein that shuttles lipids between serum lipoproteins and tissues. Overexpression of CETP in mice after 6 wk on a high-fat diet increased treadmill running duration and distance, mitochondrial oxidation of glutamate/malate, but not palmitoylcarnitine oxidation, and doubled PGC-1α mRNA concentration ( Cappel et al. 2015 ).
- The myokine musclin is a peptide secreted from exercising muscle during treadmill running. Removal of musclin release during running results in lowered VO 2max , lower skeletal muscle mitochondrial content and respiratory complex protein expression, and reduced exercise tolerance ( Subbotina et al. 2015 ).
- Lactate dehydrogenase B (LDHB), which produces pyruvate from lactate, was overexpressed in mouse skeletal muscle. Increases in markers of skeletal muscle mitochondria were associated with increased running distance in a progressive speed test, and increased peak VO 2 ( Liang et al. 2016 ).
- Another example of endurance-type exercise adaptations is the 2016 paper that transcription factor EB (TFEB) regulates metabolic flexibility in skeletal muscle independent of PGC-1α during endurance-type exercise ( Mansueto et al. 2017 ). Lack of metabolic flexibility, termed “metabolic inflexibility,” is important because it is common in T2D. One definition of metabolic inflexibility is its inability to rapidly switch between glucose and fatty acid substrates for ATP production when nutrient availability changes from high blood glucose levels immediately after a meal to decreasing below 100 mg/dl when not eating for hours after a meal. A clinical consequence of T2D-induced metabolic inflexibility is prolonged periods of hyperglycemia, because skeletal muscle is more insulin insensitive in T2D. In contrast, after sufficient endurance exercise, skeletal muscle increases its insulin sensitivity by a second pathway that is independent of proximal postreceptor insulin signaling (see Stephenson et al. 2014 for further discussion).
Studies Showing that Manipulation of One Signaling Molecule Does Not Alter Expression of All Genes with Mitochondrial Functions Found in Skeletal Muscles of Wild-Type Animals to Exercise Training
A 2010 review article ( Lira et al. 2010 ) concludes from gene-deletion studies that p38γ MAPK/PGC-1α signaling controls mitochondrial biogenesis’ adaptation to endurance exercise in skeletal muscle. Two studies do not completely agree with the conclusion in the review article. The Pilegaard laboratory published a 2008 study ( Leick et al. 2008 ) that did not confirm their hypothesis that PGC-1α was required for every metabolic protein adaptive increase after endurance-exercise training by skeletal muscle. They reported that PGC-1α was not required for endurance-training-induced increases in ALAS1, COXI, and cytochrome c expression ( Leick et al. 2008 ). Their interpretation, at that time, was that molecules other than PGC-1α can exert exercise-induced mitochondrial adaptations. A second study published in 2012 rendered a similar verdict. A 12-day program of endurance training led to the middle portion of the gastrocnemius muscle demonstrating a similar 60% increase in mitochondrial density in both wild-type and PGC-1α muscle-specific knockout mice (Myo-PGC-1αKO) ( Rowe et al. 2012 ). The paper concludes that PGC-1α is dispensable for endurance-exercise’s induction of skeletal muscle mitochondrial adaptations.
Exercise signaling targets have actions that are independent of PGC-1α, which is specific to endurance exercise. In 2002, two groups identified PGC-1β, a transcriptional coactivator closely related to PGC-1α ( Kressler et al. 2002 ; Lin et al. 2002 ). Later in 2012, the PGC-1α4 variant of PGC-1α was found to induce skeletal muscle hypertrophy and strength ( Ruas et al. 2012 ). The importance of the finding of a PGC-1α variant is that it partially explains the phenotypic variation for differing types of exercise. Since the 1970s ( Holloszy and Booth 1976 ), it has been appreciated that the biochemical and anatomical observations between endurance and resistance differed. For example, Holloszy and Booth (1976) noted in 1976 that, whereas endurance-type exercise markedly increased skeletal muscle mitochondrial density with very minor increases in muscle fiber diameter, strength-type exercise, in contrast, increased muscle fiber diameter without increases in skeletal muscle mitochondrial density. Taken together, a drug specific for PGC-1α will not likely mimic separate physical training for endurance, strength/resistance, and coordination types of exercise in the same subject. Thus, the common usage of the term exercise capacity is a misnomer because endurance training and resistance training were shown to have different exercise capacity phenotypes very long ago.
In a 2015 Diabetes paper ( Wong et al. 2015 ), Muoio’s laboratory concluded that changes in glucose tolerance and total body fat depended upon how much energy is expended in contracting muscle rather than muscle mitochondrial content or substrate selection. A finding to support the previous sentence was the glucose tolerance tests (GTTs). MCK-PGC-1α mice and their nontransgenic (NT) littermates were not different in GTT, with both being the most glucose intolerant after 10 wk of high-fat feeding. Adding 10 wk of voluntary wheel running to the two high-fat-feed groups during the next 10-wk period (weeks 11–20 of the experiment) lowered the glucose intolerance, and then during weeks 21–30 of the experiment, glucose intolerance was further lowered by adding 25% caloric restriction with the high-fat food and running during the final 10 wk. The percentage weight lost after 30 wk of high-fat feeding was positively related to greater running distances. No single front-runner gene candidate could be identified by principle component analysis. Taken together, the paper suggests “doubts” that pharmacological exercise mimetics that increase muscle oxidative capacity will be effective antiobesity and/or antidiabetic agents. Rather, Muoio and investigators suggest energy expenditure by muscle contraction induces localized shifts in energy balance inside the muscle fiber, which then initiates a broad network of metabolic intermediates regulating nutrient sensing and insulin action. A further discussion of complex biology produced by polygenicity continues next.
POLYGENICITY OF EXERCISE LEADS TO COMPLEX MULTISYSTEM RESPONSES TO IMPROVE HEALTH OUTCOMES
Multiples tissues, organs, and systems are influenced by physical activity, or the lack thereof ( Table 2 ).
Worsening of maximal functioning in selected major organ/tissue/systems that are caused by the lack of physical activity with growth, maturation, and aging
Site | Organ/tissue/system loses designated function, most with aging after maturation |
---|---|
Brain | Specific types of cognition |
Brain | Motor coordination and balance |
Heart | Maximal pumping volume/minute |
Peripheral circulation | Maximal capacity to supply blood to working muscles |
Peripheral circulation | Prevention of capillary rarefaction in feet |
Skeletal muscle | Less mass and strength |
Skeletal muscle | Lower insulin sensitivity |
Pancreas | Loss of β cells |
Aerobic capacity | Lower |
Bone | Less mass and strength |
Liver | Excessive fat storage |
The higher their maximal function is before the end of each item’s maturation, the longer chances are that the quality of life will remain optimal. The breadth of the list implies that a single molecular target will not substitute for appropriate daily physical activity to prevent the loss of all listed items.
To present one extreme, that most will agree, one molecule will not describe the 1000s of molecules adapting to aerobic, resistance, and coordination exercise training. On the opposite extreme, many could likely agree that usage of the various “omics” underlying all adaptations to physical activity will differ (i.e., not be identical in most aspects) among the next list: various cell types within a tissue/organ, tissues/organs, and various intensities of physical activity (i.e., the thresholds among gene responses for health benefits will differ because of the presence of responders and nonresponders, or protein isoform type); during various types cycling (circadian or menstrual); postprandial versus fasting between meals; male and female; child, adult, and the elderly; trained and untrained; aerobic- and resistance-exercise types; and so forth. Others have repetitively written that only ∼59% of the risk reduction for all forms of CVD have been shown to be caused by effects through traditional factors ( Mora et al. 2007 ; Joyner and Green 2009 ). Thus, we pose the next question: what is the identity of all molecules in the yet-to-be-discovered gap between our knowledge of single gene functions and the totality of personalized prescription of physical activity to maximize the period of life free of any chronic disease, termed health span?
While approaches using single-gene manipulations are valuable tools, research must also focus on integrating exercise-responsive molecules into networks that maintain or improve health. This process will reveal complex, multisystem, polygenic networking essential for the advancement of many goals pertaining to exercise physiology, such as tailoring exercise prescriptions and implementing personalized medicine. One example is the developing myokine network with auto-, para-, and endocrine molecules. The first myokine interleukin (IL)-6 began to be described as early as 1994 by the Pedersen laboratory ( Ullum et al. 1994 ), with a history of its development as the first exercise myokine recounted in 2007 ( Pedersen et al. 2007 ). Since their discovery, myokine action within and at a distance from their origins in skeletal muscle have been increasingly studied, as schematically illustrated by Schnyder and Handschin (2015) ( Fig. 2 ).
![Click on image to zoom An external file that holds a picture, illustration, etc.
Object name is cshperspectmed-BEX-029694_F2.jpg](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027933/bin/cshperspectmed-BEX-029694_F2.jpg)
Figure provides an illustration of myokine production by skeletal muscle for actions within or at a distance. Myokine release promotes a high degree of intertissue cross talk. CNTF, Ciliary neurotrophic factor; OSM, oncostatin M; IL, interleukin; BDNF, brain-derived neurotrophic factor; VEGF, vascular endothelial growth factor. (From Schnyder and Handschin 2015 ; reprinted, with permission, courtesy of PMC Open Access.)
Similarly, maximal aerobic exercise is accompanied by tremendous stress on many systems, yet whole-body homeostasis is remarkably maintained. For example, world-class endurance athletes can increase whole-body energy production well over 20-fold ( Joyner and Coyle 2008 ), whereas maintaining blood glucose concentrations at resting levels ( Wasserman 2009 ). Intuitively, such effort would require sophisticated interorgan cross talk and polygenic integration of numerous functions.
Exercise Provides Too Many Benefits to “Fit into a Single Pill”
Despite the well-known benefits of exercise, most adults and many children lead relatively sedentary lifestyles and are not active enough to achieve the health benefits of exercise ( Warburton et al. 2006 ; Fried 2016 ). Accelerometry measurements suggest that >90% of U.S. individuals >12 yr of age and ∼50% of children aged 6–11 yr old fail to meet U.S. Federal physical activity guidelines ( Troiano et al. 2008 ). Given this incredibly low compliance, the identification of genetic and/or orally active agents that mimic the effects of endurance exercise might have high appeal for a majority of sedentary individuals. This high appeal has led to recent identification/development of exercise “mimetics.” In 2009, we set criteria for proper usage of the term “exercise mimetic,” based upon its common usage ( Booth and Laye 2009 ). We gave the Oxford English Dictionary’s definition of mimetic, “A synthetic compound that produces the same (or a very similar) effect as another (especially a naturally occurring) compound.” While many exercise “mimetics” activate signaling pathways commonly associated with muscle endurance, these agents have not completely mimicked all effects for all types of exercise. For example, the AMPK activator 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), when given daily to rats over a 5-wk-period, did not increase maximal oxygen consumption (VO 2peak ) in the sedentary group of rats that were forced to run to VO 2peak on treadmills, as compared to sedentary rats receiving the vehicle ( Toedebusch et al. 2016 ). Thus, in our opinion, the published claim ( Narkar et al. 2008 ) that AICAR is an exercise mimetic is invalidated because it did not increase VO 2peak . While these agents may undoubtedly have specific health benefits, it is currently impractical to assume that all of the benefits of exercise can be replaced by “exercise mimetics.”
CONCLUDING REMARKS
Exercise is a powerful tool in the fight to prevent and treat numerous chronic diseases ( Table 1 ). Given its whole-body, health-promoting nature, the integrative responses to exercise should surely attract a great detail of interest as the notion of “exercise is medicine” continues to its integration into clinical settings.
ACKNOWLEDGMENTS
The authors disclose no conflicts of interest. Partial funding for this project was obtained from grants awarded to G.N.R. (AHA 16PRE2715005).
Editors: Juleen R. Zierath, Michael J. Joyner, and John A. Hawley
Additional Perspectives on The Biology of Exercise available at www.perspectivesinmedicine.org
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Home — Essay Samples — Nursing & Health — Physical Exercise — The Comprehensive Benefits of Exercise: A Path to Health and Wellness
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The Comprehensive Benefits of Exercise: a Path to Health and Wellness
- Categories: Healthy Lifestyle Physical Exercise
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Table of contents
Chapter 1: physical benefits of exercise, chapter 2: mental benefits of exercise, conclusion: embracing the benefits of exercise, 1. improved cardiovascular health, 2. increased muscle strength, 3. improved flexibility, 4. reduced risk of chronic diseases, 1. enhanced cognitive function, 2. improved mood and mental health, 3. stress reduction, 4. enhanced sleep quality.
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Essay on Exercise in 500+ Words for Students in English
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What are your physical fitness goals? How much do you weigh? Do you plan on running a marathon next year? The goal of all these questions is different but they involve a set of similar activities; Exercises. Physical exercises are activities that improve or maintain physical fitness and overall health. Engaging in exercise helps individuals stay physically fit and promotes mental well-being. Today, we will discuss an essay on exercise for students to highlight its importance and benefits.
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Table of Contents
- 1 Why do we Exercise?
- 2 Types of Exercise
- 3 Should We Make Exercise a Habit?
Why do we Exercise?
Exercise is like any activity that requires physical effort and helps maintain physical fitness and overall health. When we exercise, our bodies undergo numerous physiological changes, such as an increase in heart rate, which further pumps more oxygen-rich blood to our muscles. This delivery of oxygen further benefits the muscles’ ability to perform efficiently and helps improve cardiovascular perseverance.
The above effects further lead to improvements and long-term adaptations in our bodies. Further regular exercise also leads to:
- Regular exercise helps reduce the risk of heart disease and improves cardiovascular health conditions.
- Methodical exercise benefits in strengthening the muscles and making them more resistant to fatigue.
- Weight-bearing exercises help restore bone formation and reduce the risk of osteoporosis.
- Exercise can improve insulin sensitivity and help regulate blood sugar levels.
As per the study published in The Lancet Psychiatry in 2018, people who exercised were found with 43.2 percent fewer days of poor mental health than those who did not exercise. The numbers are sufficient enough to elaborate on the powerful link between physical activity and the importance of mental health in our lives.
Quick Read: Essay on Athletics
Types of Exercise
Now, as you come to know about the importance of exercise in our daily lives, similarly, it should also be noted that not all exercises are equally effective. Different physical activities offer unique benefits.
To understand it more, let us learn about some main categories of exercises:
1. Aerobic exercise: Aerobic exercise is also known as cardiovascular exercise. This physical activity helps increase heart rate and breathing. Examples of aerobic exercise include running, cycling, swimming, and brisk walking. It is important to know that Aerobic exercise is an excellent workout for cardiovascular health and calorie burning.
2. Strength Training: A strength training exercise that works against resistance to build muscle strength. This type of exercise includes weightlifting, bodyweight training, and resistance band workouts. Strength training is important for the growing age as it helps maintain muscle mass.
3. Flexibility Exercises: Flexibility exercises include stretching and practicing yoga. These physical activities improve in range of motion, reduce the risk of injury, and also help in the relaxation of muscle tension.
4. High-Intensity Interval Training (HIIT): HIIT involves exercises of intense activity followed by periods of rest or lower-intensity workouts. This type of exercise is highly effective for improving fitness and burning calories in a short amount of time.
Quick Read: International Olympic Day Essay
Should We Make Exercise a Habit?
Although we all know the benefits of exercise, many people still struggle to make it a regular part of their lives. To overcome this hurdle, here are some strategies that could help one make exercise a regular habit.
- Begin your workouts with goals that can be easily achieved. Doing 10 minutes of exercise a day is better than none.
- Find activities that you enjoy. Doing exercise does not mean going to the gym. Dancing, hiking, or sports serve the same purpose that is counted as exercise.
- Schedule your exercise like any other important appointment in your daily schedule. Mark your calendar and stick to it.
- Find friends or a team to exercise with. Support of social groups increases one´s motivation and makes exercise more enjoyable.
- The market is full of fitness applications. Find a fitness app and wearable devices that help keep track of your progress and motivate you.
- 75 to 150 minutes per week of aerobic exercise and 150 to 300 minutes of moderately intense aerobic activity help reduce the mortality of cardiovascular disease by 22% to 31%
Exercise is a powerful tool that not only helps one physically but mentally. Understanding the benefits of exercises, exploring the types of workouts, and developing strategies for doing regular aerobics helps enhance one´s well-being.
Either go for a brisk walk or do a yoga session, find whatever works for you. Physical activity should be a joyful part of your daily life and trust that your body and mind will thank you for it.
Also Read: Essay on Fitness
Ans: We all have physical fitness goals and every type of exercise can help us achieve our goals. Exercise keeps us healthy, strong, and energetic. Further, it improves one´s mood, helps in sleeping better, and reduces the risk of health diseases.
Ans: Exercise improves focus and memory. Workouts help boost self-confidence and lessen the symptoms of anxiety and depression.
Ans: Exercise strengthens one body, improves the health of the heart, and maintains a healthy weight. It increases energy, boosts flexibility, and strengthens the immune system.
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Essay on Importance of Exercise
Students are often asked to write an essay on Importance of Exercise in their schools and colleges. And if you’re also looking for the same, we have created 100-word, 250-word, and 500-word essays on the topic.
Let’s take a look…
100 Words Essay on Importance of Exercise
Introduction.
Exercise is vital for our health. It helps us stay fit, active, and healthy.
Physical Benefits
Mental benefits.
Exercise also improves our mood and reduces stress. It aids in better sleep and enhances our memory.
In conclusion, exercise is essential for our overall well-being. It is a simple and effective way to ensure a healthy life.
250 Words Essay on Importance of Exercise
Exercise is a fundamental aspect of maintaining a healthy lifestyle. It is not just about physical fitness, but it also contributes to mental health, productivity, and overall quality of life.
The Physical Impact of Exercise
Regular exercise has numerous physical benefits. It aids in maintaining a healthy weight, reducing the risk of heart diseases, and strengthening muscles and bones. Exercise also boosts the immune system, improving the body’s ability to fight off illnesses.
The Psychological Benefits of Exercise
Exercise is not just about the body; it’s equally beneficial for the mind. Regular physical activity can help reduce symptoms of depression and anxiety. It stimulates the production of endorphins, the body’s natural mood elevators, promoting a sense of well-being.
Exercise and Productivity
Exercise has been linked with increased productivity. It enhances cognitive functions, improving concentration, memory, and creativity. Regular physical activity can lead to better academic performance and efficiency in tasks.
Exercise as a Social Activity
500 words essay on importance of exercise.
Exercise is an essential component of a healthy lifestyle, often overlooked in our fast-paced modern lives. Regular physical activity fosters resilience, promotes overall well-being, and protects against various diseases. It is not just about physical health; it also has profound impacts on mental health, productivity, and overall quality of life.
The Physical Benefits of Exercise
Exercise plays a crucial role in maintaining physical health. Regular physical activity strengthens the cardiovascular system, reducing the risk of heart disease and stroke. It also helps in managing weight, as exercise increases the metabolic rate, which aids in burning more calories. Moreover, exercise enhances muscular strength and endurance, improving body composition and posture.
The Mental Health Benefits of Exercise
Exercise can significantly boost productivity and creativity. Regular physical activity improves concentration, enhances memory, speeds up cognitive processes, and stimulates creative thinking. It also increases energy levels, helping us to feel more alert and engaged throughout the day.
Exercise and Social Interaction
Promoting a culture of exercise.
In conclusion, exercise is a powerful tool for improving physical health, mental health, productivity, and social interaction. Despite the challenges of a busy lifestyle, it is essential to make time for regular physical activity. The benefits of exercise extend far beyond the immediate gratification of a good workout; they contribute to long-term health, happiness, and overall quality of life. As such, exercise should not be viewed as a chore or a luxury, but as a fundamental part of a healthy life.
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Benefits of Exercise and Importance of Overall Fitness Essay
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The Body Composition Benchmark
This paper clarifies the concepts of health and fitness, briefly explains why attaining both is essential for all ages, and imparts a beginning program for those who are truly motivated. Being in the best of health means more than the absence of illness.
Beyond avoiding the sickbed, being healthy and fit has immense physiological, cosmetic, and psychological value. Since keeping fit means staying active and engaging in a program of exercise, one gets improved muscle strength, bone density/durability, and cardiovascular tone.
In turn, better circulation improves skin tone and appearance. If your preferred exercise is playing a competitive sport, so much the better.
Stress recedes and the pleasant feeling of exhaustion afterward calms your nerves and helps you sleep better (WebMD LLC, 2009). Given these physiological benefits, exercise is great for helping prevent or delay the onset of osteoporosis, diabetes, and cardiovascular disease (Atwal, Porter, and MacDonald, 2002).
Exercise can take many forms. Start with a program of brisk walking on the treadmill at home. Or walk several laps around the track at school. Sign up for an aerobics dance class at one of many gyms around town. Or go biking around the park or forest trails and marvel at the sights you used to miss.
Since it is good to engage in exercise for the long term even if improvements in physique and health are subtle at first, it is good to have a reliable benchmark. The American Heart Association (2009) recommends keeping track of body composition: how much of your body are fat, bone, and muscle. Typically, an inactive but reasonably slender adult female may have 20-25% body fat. A nurse can measure how thick the fat layer under the skin is with calipers or run one through a bioelectrical impedance analysis device that measures resistance encountered by a low-voltage electrical current to assess body fat. After a period of exercise at some vigorous sport (multi-lap swimming or distance running), one can get fat down to as little as 10% of body mass (National Institutes of Health, 2007).
American Heart Association (2009). Body composition tests . Web.
Atwal, S., Porter, J. & MacDonald, P. (2002). Cardiovascular effect of strenuous exercise in adult recreational hockey: The Hockey Heart Study. Canadian Medical Association Journal, 166 (3); 303-307 (5 pages).
National Institutes of Health (2007). Weight management . Web.
WebMD LLC (2009). The incredible benefits of regular exercise . Web.
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Home / Essay Samples / Health / Physical Exercise / Benefits of Exercise: What Is the Real Importance
Benefits of Exercise: What Is the Real Importance
- Category: Science , Health
- Topic: Body , Human Physiology , Physical Exercise
Pages: 2 (1088 words)
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References
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- Resul Cekin ( 2015 ). Psychological benefits of regular physical activity. Universal journal of education research, 3 ( 10 ), 710-717.
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- Effect of regular exercise on anxiety and self-esteem level in college students. Althea medical journal, 2 ( 3 ), 429-432.
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