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How to Make a Research Paper Title with Examples

how to come up with a good title for research paper

What is a research paper title and why does it matter?

A research paper title summarizes the aim and purpose of your research study. Making a title for your research is one of the most important decisions when writing an article to publish in journals. The research title is the first thing that journal editors and reviewers see when they look at your paper and the only piece of information that fellow researchers will see in a database or search engine query. Good titles that are concise and contain all the relevant terms have been shown to increase citation counts and Altmetric scores .

Therefore, when you title research work, make sure it captures all of the relevant aspects of your study, including the specific topic and problem being investigated. It also should present these elements in a way that is accessible and will captivate readers. Follow these steps to learn how to make a good research title for your work.

How to Make a Research Paper Title in 5 Steps

You might wonder how you are supposed to pick a title from all the content that your manuscript contains—how are you supposed to choose? What will make your research paper title come up in search engines and what will make the people in your field read it? 

In a nutshell, your research title should accurately capture what you have done, it should sound interesting to the people who work on the same or a similar topic, and it should contain the important title keywords that other researchers use when looking for literature in databases. To make the title writing process as simple as possible, we have broken it down into 5 simple steps.

Step 1: Answer some key questions about your research paper

What does your paper seek to answer and what does it accomplish? Try to answer these questions as briefly as possible. You can create these questions by going through each section of your paper and finding the MOST relevant information to make a research title.

Step 2: Identify research study keywords

Now that you have answers to your research questions, find the most important parts of these responses and make these your study keywords. Note that you should only choose the most important terms for your keywords–journals usually request anywhere from 3 to 8 keywords maximum.

Step 3: Research title writing: use these keywords

“We employed a case study of 60 liver transplant patients around the US aged 20-50 years to assess how waiting list volume affects the outcomes of liver transplantation in patients; results indicate a positive correlation between increased waiting list volume and negative prognosis after the transplant procedure.”

The sentence above is clearly much too long for a research paper title. This is why you will trim and polish your title in the next two steps.

Step 4: Create a working research paper title

To create a working title, remove elements that make it a complete “sentence” but keep everything that is important to what the study is about. Delete all unnecessary and redundant words that are not central to the study or that researchers would most likely not use in a database search.

“ We employed a case study of 60 liver transplant patients around the US aged 20-50 years to assess how the waiting list volume affects the outcome of liver transplantation in patients ; results indicate a positive correlation between increased waiting list volume and a negative prognosis after transplant procedure ”

Now shift some words around for proper syntax and rephrase it a bit to shorten the length and make it leaner and more natural. What you are left with is:

“A case study of 60 liver transplant patients around the US aged 20-50 years assessing the impact of waiting list volume on outcome of transplantation and showing a positive correlation between increased waiting list volume and a negative prognosis” (Word Count: 38)

This text is getting closer to what we want in a research title, which is just the most important information. But note that the word count for this working title is still 38 words, whereas the average length of published journal article titles is 16 words or fewer. Therefore, we should eliminate some words and phrases that are not essential to this title.

Step 5: Remove any nonessential words and phrases from your title

Because the number of patients studied and the exact outcome are not the most essential parts of this paper, remove these elements first:

 “A case study of 60 liver transplant patients around the US aged 20-50 years assessing the impact of waiting list volume on outcomes of transplantation and showing a positive correlation between increased waiting list volume and a negative prognosis” (Word Count: 19)

In addition, the methods used in a study are not usually the most searched-for keywords in databases and represent additional details that you may want to remove to make your title leaner. So what is left is:

“Assessing the impact of waiting list volume on outcome and prognosis in liver transplantation patients” (Word Count: 15)

In this final version of the title, one can immediately recognize the subject and what objectives the study aims to achieve. Note that the most important terms appear at the beginning and end of the title: “Assessing,” which is the main action of the study, is placed at the beginning; and “liver transplantation patients,” the specific subject of the study, is placed at the end.

This will aid significantly in your research paper title being found in search engines and database queries, which means that a lot more researchers will be able to locate your article once it is published. In fact, a 2014 review of more than 150,000 papers submitted to the UK’s Research Excellence Framework (REF) database found the style of a paper’s title impacted the number of citations it would typically receive. In most disciplines, articles with shorter, more concise titles yielded more citations.

Adding a Research Paper Subtitle

If your title might require a subtitle to provide more immediate details about your methodology or sample, you can do this by adding this information after a colon:

“ : a case study of US adult patients ages 20-25”

If we abide strictly by our word count rule this may not be necessary or recommended. But every journal has its own standard formatting and style guidelines for research paper titles, so it is a good idea to be aware of the specific journal author instructions , not just when you write the manuscript but also to decide how to create a good title for it.

Research Paper Title Examples

The title examples in the following table illustrate how a title can be interesting but incomplete, complete by uninteresting, complete and interesting but too informal in tone, or some other combination of these. A good research paper title should meet all the requirements in the four columns below.

Tips on Formulating a Good Research Paper Title

In addition to the steps given above, there are a few other important things you want to keep in mind when it comes to how to write a research paper title, regarding formatting, word count, and content:

  • Write the title after you’ve written your paper and abstract
  • Include all of the essential terms in your paper
  • Keep it short and to the point (~16 words or fewer)
  • Avoid unnecessary jargon and abbreviations
  • Use keywords that capture the content of your paper
  • Never include a period at the end—your title is NOT a sentence

Research Paper Writing Resources

We hope this article has been helpful in teaching you how to craft your research paper title. But you might still want to dig deeper into different journal title formats and categories that might be more suitable for specific article types or need help with writing a cover letter for your manuscript submission.

In addition to getting English proofreading services , including paper editing services , before submission to journals, be sure to visit our academic resources papers. Here you can find dozens of articles on manuscript writing, from drafting an outline to finding a target journal to submit to.

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  • How to Write a Great Title

Title

Maximize search-ability and engage your readers from the very beginning

Your title is the first thing anyone who reads your article is going to see, and for many it will be where they stop reading. Learn how to write a title that helps readers find your article, draws your audience in and sets the stage for your research!

How your title impacts the success of your article

Researchers are busy and there will always be more articles to read than time to read them.  Good titles help readers find your research, and decide whether to keep reading. Search engines use titles to retrieve relevant articles based on users’ keyword searches. Once readers find your article, they’ll use the title as the first filter to decide whether your research is what they’re looking for. A strong and specific title is the first step toward citations, inclusion in meta-analyses, and influencing your field. 

how to come up with a good title for research paper

What to include in a title

Include the most important information that will signal to your target audience that they should keep reading.

Key information about the study design

Important keywords

What you discovered

Writing tips

Getting the title right can be more difficult than it seems, and researchers refine their writing skills throughout their career. Some journals even help editors to re-write their titles during the publication process! 

how to come up with a good title for research paper

  • Keep it concise and informative What’s appropriate for titles varies greatly across disciplines. Take a look at some articles published in your field, and check the journal guidelines for character limits. Aim for fewer than 12 words, and check for journal specific word limits.
  • Write for your audience Consider who your primary audience is: are they specialists in your specific field, are they cross-disciplinary, are they non-specialists?
  • Entice the reader Find a way to pique your readers’ interest, give them enough information to keep them reading.
  • Incorporate important keywords Consider what about your article will be most interesting to your audience: Most readers come to an article from a search engine, so take some time and include the important ones in your title!
  • Write in sentence case In scientific writing, titles are given in sentence case. Capitalize only the first word of the text, proper nouns, and genus names. See our examples below.

how to come up with a good title for research paper

Don’t

  • Write your title as a question In most cases, you shouldn’t need to frame your title as a question. You have the answers, you know what you found. Writing your title as a question might draw your readers in, but it’s more likely to put them off.
  • Sensationalize your research Be honest with yourself about what you truly discovered. A sensationalized or dramatic title might make a few extra people read a bit further into your article, but you don’t want them disappointed when they get to the results.

Examples…

Format: Prevalence of [disease] in [population] in [location]

Example: Prevalence of tuberculosis in homeless women in San Francisco

Format: Risk factors for [condition] among [population] in [location]

Example: Risk factors for preterm births among low-income women in Mexico City

Format (systematic review/meta-analysis): Effectiveness of [treatment] for [disease] in [population] for [outcome] : A systematic review and meta-analysis

Example: Effectiveness of Hepatitis B treatment in HIV-infected adolescents in the prevention of liver disease: A systematic review and meta-analysis

Format (clinical trial): [Intervention] improved [symptoms] of [disease] in [population] : A randomized controlled clinical trial

Example: Using a sleep app lessened insomnia in post-menopausal women in southwest United States: A randomized controlled clinical trial

Format  (general molecular studies): Characterization/identification/evaluation of [molecule name] in/from [organism/tissue] (b y [specific biological methods] ) 

Example: Identification of putative Type-I sex pheromone biosynthesis-related genes expressed in the female pheromone gland of Streltzoviella insularis

Format  (general molecular studies): [specific methods/analysis] of organism/tissue reveal insights into [function/role] of [molecule name] in [biological process]  

Example: Transcriptome landscape of Rafflesia cantleyi floral buds reveals insights into the roles of transcription factors and phytohormones in flower development

Format  (software/method papers): [tool/method/software] for [what purpose] in [what research area]

Example: CRISPR-based tools for targeted transcriptional and epigenetic regulation in plants

Tip: How to edit your work

Editing is challenging, especially if you are acting as both a writer and an editor. Read our guidelines for advice on how to refine your work, including useful tips for setting your intentions, re-review, and consultation with colleagues.

  • How to Write an Abstract
  • How to Write Your Methods
  • How to Report Statistics
  • How to Write Discussions and Conclusions
  • How to Edit Your Work

The contents of the Peer Review Center are also available as a live, interactive training session, complete with slides, talking points, and activities. …

The contents of the Writing Center are also available as a live, interactive training session, complete with slides, talking points, and activities. …

There’s a lot to consider when deciding where to submit your work. Learn how to choose a journal that will help your study reach its audience, while reflecting your values as a researcher…

Enago Academy

6 Important Tips on Writing a Research Paper Title

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When you are searching for a research study on a particular topic, you probably notice that articles with interesting, descriptive research titles draw you in. By contrast, research paper titles that are not descriptive are usually passed over, even though you may write a good research paper with interesting contents. This shows the importance of coming up with a good title for your research paper when drafting your own manuscript.

Importance of a Research Title

The research title plays a crucial role in the research process, and its importance can be summarized as follows:

Importance of a Research Title

Why do Research Titles Matter?

Before we look at how to title a research paper, let’s look at a research title example that illustrates why a good research paper should have a strong title.

Imagine that you are researching meditation and nursing, and you want to find out if any studies have shown that meditation makes nurses better communicators.  You conduct a keyword search using the keywords “nursing”, “communication”, and “meditation.” You come up with results that have the following titles:

  • Benefits of Meditation for the Nursing Profession: A Quantitative Investigation
  • Why Mindful Nurses Make the Best Communicators
  • Meditation Gurus
  • Nurses on the Move: A Quantitative Report on How Meditation Can Improve Nurse Performance

All four of these research paper titles may describe very similar studies—they could even be titles for the same study! As you can see, they give very different impressions.

  • Title 1 describes the topic and the method of the study but is not particularly catchy.
  • Title 2 partly describes the topic, but does not give any information about the method of the study—it could simply be a theoretical or opinion piece.
  • Title 3 is somewhat catchier but gives almost no information at all about the article.
  • Title 4 begins with a catchy main title and is followed by a subtitle that gives information about the content and method of the study.

As we will see, Title 4 has all the characteristics of a good research title.

Characteristics of a Good Research Title

According to rhetoric scholars Hairston and Keene, making a good title for a paper involves ensuring that the title of the research accomplishes four goals as mentioned below:

  • It should predict the content of the research paper .
  • It should be interesting to the reader .
  • It should reflect the tone of the writing .
  • It should contain important keywords that will make it easier to be located during a keyword search.

Let’s return to the examples in the previous section to see how to make a research title.

As you can see in the table above, only one of the four example titles fulfills all of the criteria of a suitable research paper title.

Related: You’ve chosen your study topic, but having trouble deciding where to publish it? Here’s a comprehensive course to help you identify the right journal .

Tips for Writing an Effective Research Paper Title

When writing a research title, you can use the four criteria listed above as a guide. Here are a few other tips you can use to make sure your title will be part of the recipe for an effective research paper :

  • Make sure your research title describes (a) the topic, (b) the method, (c) the sample, and (d) the results of your study. You can use the following formula:
[ Result ]: A [ method ] study of [ topic ] among [ sample ] Example : Meditation makes nurses perform better: a qualitative study of mindfulness meditation among German nursing students
  • Avoid unnecessary words and jargons. Keep the title statement as concise as possible. You want a title that will be comprehensible even to people who are not experts in your field. Check our article for a detailed list of things to avoid when writing an effective research title .
  • Make sure your title is between 5 and 15 words in length.
  • If you are writing a title for a university assignment or for a particular academic journal, verify that your title conforms to the standards and requirements for that outlet. For example, many journals require that titles fall under a character limit, including spaces. Many universities require that titles take a very specific form, limiting your creativity.
  • Use a descriptive phrase to convey the purpose of your research efficiently.
  • Most importantly, use critical keywords in the title to increase the discoverability of your article.

how to come up with a good title for research paper

Resources for Further Reading

In addition to the tips above, there are many resources online that you can use to help write your research title. Here is a list of links that you may find useful as you work on creating an excellent research title:

  • The University of Southern California has a guide specific to social science research papers: http://libguides.usc.edu/writingguide/title
  • The Journal of European Psychology Students has a blog article focusing on APA-compliant research paper titles: http://blog.efpsa.org/2012/09/01/how-to-write-a-good-title-for-journal-articles/
  • This article by Kristen Hamlin contains a step-by-step approach to writing titles: http://classroom.synonym.com/choose-title-research-paper-4332.html

Are there any tips or tricks you find useful in crafting research titles? Which tip did you find most useful in this article? Leave a comment to let us know!

  • Hairston, M., & Keene, M. 2003. Successful writing . 5th ed. New York: Norton.
  • University of Southern California. 2017. Organizing your social sciences research paper: choosing a title . [Online] Available at: http://libguides.usc.edu/writingguide/title

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Thank you so much:) Have a nice day!

Thank you so much, it helped me.. God bless..

Thank you for the excellent article and tips for creating a research work, because I always forget about such an essential element as the keywords when forming topics. In particular, I have found a rapid help with the formation of informative and sound titles that also conforms to the standards and requirements.

I am doing a research work on sales girls or shop girls using qualititative method. Basicly I am from Pakistan and writing on the scenario of mycountry. I am really confused about my research title can you kindly give some suggestions and give me an approperaite tilte

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Hi Zubair, Thank you for your question. However, the information you have provided is insufficient for drafting an appropriate title. Information on what exactly you intend to study would be needed in order to draft a meaningful title. Meanwhile, you can try drafting your own title after going through the following articles our website: https://www.enago.com/academy/top-10-tips-on-choosing-an-attractive-research-title/ , https://www.enago.com/academy/writing-a-good-research-title-things-to-avoid/ , https://www.enago.com/academy/write-irresistible-research-paper-title/ We would be happy to give you feedback and suggest changes if required. Did you get a chance to install our free Mobile App? https://www.enago.com/academy/mobile-app/ . Make sure you subscribe to our weekly newsletter https://www.enago.com/academy/subscribe-now/ .

thanks for helping me like this!!

Thank you for this. It helped me improve my research title. I just want to verify to you the title I have just made. “Ensuring the safety: A Quantitative Study of Radio Frequency Identification system among the selected students of ( school’s name ).

(I need your reply asap coz we will be doing the chap. 1 tomorrow. Thank u in advance. 🙂 )

I am actually doing a research paper title. I want to know more further in doing research title. Can you give me some tips on doing a research paper?

Hi Joan, Thank you for your question. We are glad to know that you found our resources useful. Your feedback is very valuable to us. You can try drafting your own title after going through the following articles on our website: https://www.enago.com/academy/top-10-tips-on-choosing-an-attractive-research-title/ , https://www.enago.com/academy/writing-a-good-research-title-things-to-avoid/ , https://www.enago.com/academy/write-irresistible-research-paper-title/

We would be happy to give you feedback and suggest changes if required. Did you get a chance to install our free Mobile App? https://www.enago.com/academy/mobile-app/ . Make sure you subscribe to our weekly newsletter https://www.enago.com/academy/subscribe-now/ .

That really helpful. Thanks alot

Thank you so much. It’s really help me.

Thanks for sharing this tips. Title matters a lot for any article because it contents Keywords of article. It should be eye-catchy. Your article is helpful to select title of any article.

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This blog is very informative for me. Thanks for sharing.

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i’m found in selecting my ma thesis title ,so i’m going to do my final research after the proposal approved. Your post help me find good title.

I need help. I need a research title for my study about early mobilization of the mechanically ventilated patients in the ICU. Any suggestions would be highly appreciated.

Thank you for posting your query on the website. When writing manuscripts, too many scholars neglect the research title. This phrase, along with the abstract, is what people will mostly see and read online. Title research of publications shows that the research paper title does matter a lot. Both bibliometrics and altmetrics tracking of citations are now, for better or worse, used to gauge a paper’s “success” for its author(s) and the journal publishing it. Interesting research topics coupled with good or clever yet accurate research titles can draw more attention to your work from peers and the public alike. You can check through the following search results for titles on similar topics: https://www.google.com/search?q=early+mobilization+of+the+mechanically+ventilated+patients+in+the+icu&rlz=1C1GCEU_enIN907IN907&oq=&aqs=chrome.0.69i59.4920093j0j7&sourceid=chrome&ie=UTF-8 .

We hope this would be helpful in drafting an attractive title for your research paper.

Please let us know in case of any other queries.

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In case the topic is new research before you’re writing. And then to stand out, you end up being different.and be inclined to highlight yourself.

There are many free directories, and more paid lists.

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Ever find it hard to come up with a catchy title for your research paper? You're not alone! Many people struggle with creating titles that grab attention and show what their work is about.

It can be frustrating because your title is like a first impression. If it's not interesting, people might ignore your research. 

But no worries! 

In this blog, we'll give you practical tips and examples to make sure your research paper title stands out. 

Whether you're a beginner or an expert, we want to help you write research paper titles that would make others excited about your work!

So, let’s get started.

Arrow Down

  • 1. What is a Research Paper Title, and Why Does it Matter?
  • 2. How to Write a Good Research Paper Title in 5 Steps
  • 3. Step 2: Keep it Clear and Concise
  • 4. Research Paper Title Examples
  • 5. Tips for Writing an Effective Research Paper Title

What is a Research Paper Title, and Why Does it Matter?

A research paper title is like the name tag for your work. It tells people what your research paper is about. It's the first thing readers see, and it's important because it helps them decide if they want to read more.

Think of it like this: Have you ever picked up a book because the title sounded interesting? It's kind of the same idea. A good title grabs attention and makes people curious about what's inside.

In the world of research, a well-crafted title is crucial because it sets the stage for your whole paper. 

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Key Characteristics of a Good Research Paper Title

Here are some important factors that create an engaging and interesting research paper title:

  • Clarity and Precision: Clearly conveys the main idea.
  • Relevance to Content: Reflects core focus and findings.
  • Conciseness: Keeps title brief and to the point.
  • Keywords and Phrases: Includes important search keywords.
  • Captivating Language: Engages interest without sacrificing accuracy.
  • Reflects Paper's Tone: Matches the research paper's tone and style.

How to Write a Good Research Paper Title in 5 Steps

Writing an effective research paper title doesn't have to be difficult. Follow these five straightforward steps to craft a title that not only reflects your research but also captures the reader's interest.

Step 1: Understand Your Paper's Main Message

Think of your research as a big idea or a story. Imagine it as the most important thing you want to share with others. 

Ask yourself: What's the main thing or research problem I want people to know about my research? 

Once you're clear on this, you're ready to move on.

Step 2: Keep it Clear and Concise

When making your title, make it short and simple. Don't use too many words or make it confusing. 

The goal is to make it easy for people to understand what your paper is about right away. Think of it like telling a quick and clear story with your title!

Step 3: Be Specific, Not Too General

When writing your title, make sure it talks about your research and not just anything general. Don't use titles that could fit lots of different studies. 

Being specific helps people know exactly what your paper is going to tell them. It's like giving them a clear roadmap to your research!

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Step 4: Inject a Hint of Creativity or Intrigue

Make your title a little exciting! Use engaging words or ask a fun question to make people curious. Imagine your title as a little mystery that makes them want to learn more

Step 5: Check for Keywords and Relevance

Think about the words people might use when searching for research like yours. Use those words in your title to help people find your work. 

Including relevant keywords can improve the visibility of your paper in searches.

Adding a Research Paper Subtitle

A research paper subtitle is like an extra description that comes after the main title. It gives more details about what your research is about. 

Adding a subtitle is a choice, but it can be helpful. If your main title is short and you want to say more about your research, a subtitle is a good idea. 

It's like a bonus that provides extra information for readers. Consider using a subtitle when you want to give a bit more insight into your research topic.

Research Paper Title Examples

Check out the examples below and see how they perform in front of different factors:

Tips for Writing an Effective Research Paper Title

Follow these tips to make your research paper title engaging and attention-grabbing:

  • Add important words related to your research for better search results.
  • Make your title brief and clear to convey your research focus effectively.
  • Use words that grab attention and spark curiosity about your study.
  • Craft a title that anyone, whether an expert or newcomer, can understand.
  • Aim for a title that's not too general or too technical, striking the right balance.

In conclusion,

Writing a standout research paper title is a crucial step to ensure your work gets the attention it deserves. Following the simple tips shared in this guide can help you create a title that is clear, engaging, and perfectly aligned with your research focus. 

Remember, your title is the first thing readers see, so making it count is key!

However, if you need writing assistance, MyPerfectWords.com is here for you. Our skilled writers are not only ready to help with writing compelling titles but can also write custom research paper just for you.

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How to write a good research paper title

“Unread science is lost science .”

how to come up with a good title for research paper

Credit: Mykyta Dolmatov/Getty

“Unread science is lost science.”

28 July 2020

how to come up with a good title for research paper

Mykyta Dolmatov/Getty

With the influx of publications brought on by the pandemic, it’s become more challenging than ever for researchers to attract attention to their work.

Understanding which elements of a title will attract readers – or turn them away – has been proven to increase a paper’s citations and Altmetric score .

“In the era of information overload, most students and researchers do not have time to browse the entire text of a paper,” says Patrick Pu , a librarian at the National University of Singapore.

“The title of a paper, together with its abstract, become very important to capture and sustain the attention of readers.”

1. A good title avoids technical language

Since the primary audience of a paper is likely to be researchers working in the same field, using technical language in the title seems to make sense.

But this alienates the wider lay audience, which can bring valuable attention to your work . It can also alienate inexperienced researchers, or those who have recently entered the field.

“A good title does not use unnecessary jargon,” says Elisa De Ranieri , editor-in-chief at the Nature Communications journal (published by Springer Nature, which also publishes Nature Index.) “It communicates the main results in the study in a way that is clear and accessible, ideally to non-specialists or researchers new to the field.”

How-to: When crafting a title, says De Ranieri, write down the main result of the manuscript in a short paragraph. Shorten the text to make it more concise, while still remaining descriptive. Repeat this process until you have a title of fewer than 15 words.

2. A good title is easily searchable

Most readers today are accessing e-journals, which are indexed in scholarly databases such as Scopus and Google Scholar.

“Although these databases usually index the full text of papers, retrieval weightage for ‘Title’ is usually higher than other fields, such as ‘Results’,” Pu explains.

At the National University of Singapore, Pu and his colleagues run information literacy programmes for editors and authors. They give advice for publishing best practice, such as how to identify the most commonly used keywords in literature searches in a given field.

“A professor once told us how he discovered that industry experts were using a different term or keyword to describe his research area,” says Pu.

“He had written a seminal paper that did not include this ‘industry keyword’. He believes his paper, which was highly cited by academics, would have a higher citation count if he had included this keyword in the title. As librarians, we try to highlight this example to our students so that they will consider all possible keywords to use in their searches and paper titles.”

How-to: Authors should speak to an academic librarian at their institution to gain an understanding of keyword and search trends in their field of research. This should inform how the paper title is written.

3. A good title is substantiated by data

Authors should be cautious to not make any claims in the title that can’t be backed up by evidence.

“For instance, if you make a discovery with potential therapeutic relevance, the title should specify whether it was tested or studied in animals or humans/human samples,” says Irene Jarchum , senior editor at the journal Nature Biotechnology (also published by Springer Nature, which publishes the Nature Index.)

Jarchum adds that titles can be contentious because different authors have different views on the use of specific words, such as acronyms, or more fundamentally, what the main message of the title should be.

Some authors may over-interpret the significance of their preliminary findings, and want to reflect this in the title.

How-to: If you know your paper will be contentious within the scientific community, have the data ready to defend your decisions .

4. A good title sparks curiosity

A one-liner that sparks a reader’s interest can be very effective.

“A title has to pique the interest of the person searching for literature in a split-second – enough that they click on the title to read the abstract. Unread science is lost science,” says Christine Mayer , editor-in-chief of the journal Advanced Therapeutics .

Paper titles such as, "White and wonderful? Microplastics prevail in snow from the Alps to the Arctic" ( 2019 Science ), and “Kids these days: Why the youth of today seem lacking” ( 2019 Science Advances ) are good examples of this principle. Both papers have high Altmetric Attention scores, indicating that they have been widely read and discussed online.

How-to: Take note of the characteristics of paper titles that spark your own interest. Keep a record of these and apply the same principles to your own paper titles.

How to Write a Good Research Paper Title

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Table of contents

  • 1 Characteristics of a Good Title
  • 2.1 Start with a Working Title
  • 2.2 Prioritize Important Terms
  • 2.3 Use Active Verbs
  • 2.4 Avoid Clickbait Techniques
  • 2.5 Keep It Short But Informative
  • 2.6 Limit Vague Statements
  • 2.7 Mention the Study Design
  • 2.8 Avoid Abbreviations
  • 2.9 Check for Similiar Titles
  • 2.10 Don’t Be Too Technical and Forgetting Your Audience
  • 3.1 Good and Bad Titles for a Research Paper
  • 3.2 How to Title Research Paper in Your Field
  • 4 Our Take on Crafting Research Paper Titles

While working on a scientific academic paper, writing a good research paper title is probably the least of your concerns. However, it becomes an “issue” down the drain when it comes to combining all the necessary elements of a great-sounding title in one heading.

The PapersOwl team wanted to help you figure it out, so we’ve created this guide on writing a catchy, topic-relevant title. Here’s what you’ll learn after going through this guide:

  • We will delve into the essential attributes that make a research paper title effective and attention-grabbing, helping you understand what constitutes a good title.
  • Give you practical tips on how to optimize your research paper heading in alignment with established academic guidelines.
  • We will walk you through a process outlining the steps you should take to create a heading.
  • Real-world examples of research paper headings will show how you can successfully encapsulate the essence of their respective papers.
  • Here, you will find strategies and considerations for phrasing your paper title to resonate with a specific research discipline.

Let’s take it one step at a time, so we’ll dive into the elements of a great heading to show you what your heading should sound like first.

Characteristics of a Good Title

To write a perfect research paper title, you’ll need to know about the different types of headings first:

  • Interrogative
  • Humorous or colloquial

The key point for all these types is to make a catchy title that captures the tone and the essence of the topic with relevant keywords . If you decide to name a research paper with the interrogative approach, you can use the phrasing of a question-type heading to entice the readers to look for an answer.

Suggestive headings are a bit different as they indicate that a reader will have to keep reading to get an answer to the outlined thesis, only without phrasing it as a question. This is where things get interesting and start depending on the topic more because a humorous or colloquial title can’t always be used.

You should use these only if the title of the research topic allows it to be phrased in a common language and colloquial. Finally, the combined approach takes something from all these types and often makes the best option for general topics. You can take a look at our list to see what we mean by these characteristics:

Tips for Crafting the Perfect Title

If you are wondering about how to write a title for a research paper, you’ll find a lot of common knowledge tips for writing research paper titles. You may hear that it needs to be on-point, short, yet catchy and that it has to be interesting enough without compromising on keywords.

We also recommend that you keep in mind the formatting guidelines, including the APA format or another requested format. Still, we think it’s better to give you a more detailed set of tips to follow, so here’s our list of the most useful steps to take:

Start with a Working Title

The first tip we’ll give you is not to waste too much time wondering how to title a research paper. You should start with a working title that can be edited, revised and changed afterward.

Make sure to finish writing your paper first, and only then can you truly dedicate your time to creating a perfect title. By that time, you’ll already get a few ideas along the way, so try to think about how each new chapter may contribute as inspiration for the final title of the research project.

Prioritize Important Terms

It’s no secret that good research paper tiles simply need to include important and relevant terms in the paper. Since you won’t be able to make it a mile-long heading, it’s important to start with those terms first and try to build the rest around them.

We recommend writing down a few key terms for your research and topic in the heading first and then brainstorming ideas on how to make it sound catchy and fill up the gaps afterward.

Use Active Verbs

If you look at the good research paper title examples, you’ll notice a common denominator. Most of these headings have active verbs, which means you shouldn’t use verbs like “Study on” or “Analysis of”.

Instead, you can use active verbs like “Evaluating”, “Examining”, “Establishing”, “Interpreting”, and so on.

Avoid Clickbait Techniques

One of the most important things is not to make the title of the research paper sound like clickbait. Sure, it’s important to make it sound catchy and enticing, but avoid using the same format as clickbait news or journals.

The biggest difference between these two types of headings is that clickbait often doesn’t contain that much information on what seems to be the key thesis of the topic. It only serves to attract more readers and clicks.

However, your scientific paper’s title has to be on point with relevant topic keywords.

Keep It Short But Informative

This one is worth its weight in gold since there’s usually a certain word count limit for the research paper title. It may not be enforced strictly, but it’s still important to make the title short and concise to avoid topic confusion for the readers.

You can aim for around 10 to 12 words, just like with our example of a good title listed in the table above. Make sure to use a few relevant terms about your research first, and then fill in the gaps to create a title.

Limit Vague Statements

As we dive into the research paper title format more and more, you’ll notice that some titles feature vague statements. These are among the worst mistakes you can make, even though it initially may seem like vague titles are more enticing.

In reality, these are not news articles, so you’ll have to make a title catchy in another way and keep the heading specifically related to your research.

Mention the Study Design

If you have enough room in your title, you can also mention the study design. This means you can lay out a few details about the nature of your research methodology or variables used to explain certain scientific occurrences.

There’s no need to overdo it; you can simply create a catchy title and add something like “Using the (method name) method”, so it reveals something topic-related and represents your research.

Avoid Abbreviations

When coming up with the research paper name, it’s crucial to avoid abbreviations. Of course, this doesn’t reflect on the measurement units or similar pieces of data, but it’s better to steer away from these titles for research papers altogether.

Things can get a bit complex here since abbreviations may not be considered wrong if previously defined, but that would also consume too much space. So, make it simple and avoid using any acronyms or abbreviations within the title itself, but rather in the content sections.

Check for Similiar Titles

Sadly, this happens a lot more often than you would imagine, especially if you are a student working on research that’s commonly used as a subject. You may run into a problem if previous generations of students have used too similar or possibly even the same titles.

So, it’s best to check all this beforehand, and it goes the same way for scientific studies outside the academic frame. Also, when looking for custom research papers for sale , it’s important to make sure that the headings aren’t copied in any way.

Don’t Be Too Technical and Forgetting Your Audience

Finally, we have to encourage you to always keep in mind the tone of your research when naming a research paper. If the tone allows, you can get into the technical details, but make sure not to overdo it if that doesn’t suit the tone of the paper.

Try to think about the audience and who will read the research. This is the best way to not only create catchy research paper titles but also to ensure the use of the right voice. It’s also important to use the right style, depending on whether you are required to use the MLA guidelines or another format.

Examples of Research Paper Titles

After going through the technicalities, it’s time to give you a sample of title headings to show you what we mean in practice. We’ll also be giving you good and bad research title examples with a focus on the mentioned tips and steps for crafting a great title.

Good and Bad Titles for a Research Paper

We know it’s difficult to come up with a title for a research paper at first, but looking at the examples might help differentiate between good titles for research papers and bad ones. For instance, differentiating between vague and solid titles gets easier when you look at these few examples:

Vague: “A Study On Birds”

Improved: “Analyzing Migration Patterns of North American Sparrows”

Here’s another example of a vague title – “A Study on Facebook,” so you can see it’s pretty vague and short. An improved version would be “The Effects of Social Media on Psychological Health and Well-Being.”

It also comes in handy to differentiate between overly technical titles and acceptable titles with a glimpse of technical details. For example, the title “The Effect of 2,4-Dinitrophenol on ATP Synthase Activity in Mitochondria” can be simplified for wider audiences if needed.

You can use something like “Understanding the Impact of 2,4-Dinitrophenol on Cellular Energy Production” to make the title a bit catchier and acceptable for a wider audience.

How to Title Research Paper in Your Field

If you are still having some doubts even after going through all these tips, we completely get you. It’s not so easy to form a title for a research paper in practice, so we’ll put some of our skills to use to give you a few creative examples to lean on when figuring out your heading:

Titles for psychology research papers:

  • Natural Methods For Fighting Stress Quickly and Effectively
  • How to Make People Do What You Want: 5 Most Effective Methods
  • A Full Guide on How Not to Be Influenced by Society
  • Correlation Between Aggressive Adult Behaviour And An Unhappy Childhood
  • How to Change Your Attitude to Life: Natural Methods That Really Work

Education and related topics:

  • How to Get As and Work at the Same Time: Time-Management Tips for Students
  • A Guide on How to Craft a Good Essay if You Have Only 1 Hour
  • You Mean Nothing to Society if You Don’t Have a Degree
  • Steps that Should be Taken to Improve the System of Education
  • Great Tricks for Motivating Students

Heading examples for business papers:

  • How to Start Your Own Business Without a Large Investment
  • Benefits of Being Self-Employed You Have Never Thought Of
  • 10 Great Business Ideas for Those Who Have No Money
  • The Most Common Mistakes Beginning Businessmen Do
  • The Secret Behind a Successful Business

Ideas for papers from the technology sphere:

  • The Greatest Innovations in Technology in the Last 5 Years
  • The Most Useful Technologies in Medicine
  • Original Technologies that Will Change the Future
  • The Role of Information Technology in Everyday Life
  • The Benefits of Living in a Highly-Technological World

You can also rely on a research paper proofreading service to help out with some minor details that could make a change both for the title and the paper itself.

If you are facing issues with the research paper title ideas, we recommend that you save it for last and finish your work first before crafting a title.

This usually helps as you’ll have more inspiration after you’ve gone in-depth with the topic, and the heading may come naturally to you. If not, you can always refer to the PapersOwl team and have it crafted by our experts.

Our Take on Crafting Research Paper Titles

To summarize, everyone can tell you how it is to make a title for a research paper by making it sound catchy and topic-relevant. However, we have outlined all the necessary details in-depth through this guide so you can truly craft an admirable title for a research project.

The key is to know your audience, avoid vague titles and short word forms, and keep an active voice with a focus on relevant terms. So, we hope that this guide will serve as a pathway toward a perfect scientific title for your project.

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how to come up with a good title for research paper

  • USC Libraries
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Organizing Your Social Sciences Research Paper

  • Choosing a Title
  • Purpose of Guide
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The title summarizes the main idea or ideas of your study. A good title contains the fewest possible words needed to adequately describe the content and/or purpose of your research paper.

Importance of Choosing a Good Title

The title is the part of a paper that is read the most, and it is usually read first . It is, therefore, the most important element that defines the research study. With this in mind, avoid the following when creating a title:

  • If the title is too long, this usually indicates there are too many unnecessary words. Avoid language, such as, "A Study to Investigate the...," or "An Examination of the...." These phrases are obvious and generally superfluous unless they are necessary to covey the scope, intent, or type of a study.
  • On the other hand, a title which is too short often uses words which are too broad and, thus, does not tell the reader what is being studied. For example, a paper with the title, "African Politics" is so non-specific the title could be the title of a book and so ambiguous that it could refer to anything associated with politics in Africa. A good title should provide information about the focus and/or scope of your research study.
  • In academic writing, catchy phrases or non-specific language may be used, but only if it's within the context of the study [e.g., "Fair and Impartial Jury--Catch as Catch Can"]. However, in most cases, you should avoid including words or phrases that do not help the reader understand the purpose of your paper.
  • Academic writing is a serious and deliberate endeavor. Avoid using humorous or clever journalistic styles of phrasing when creating the title to your paper. Journalistic headlines often use emotional adjectives [e.g., incredible, amazing, effortless] to highlight a problem experienced by the reader or use "trigger words" or interrogative words like how, what, when, or why to persuade people to read the article or click on a link. These approaches are viewed as counter-productive in academic writing. A reader does not need clever or humorous titles to catch their attention because the act of reading research is assumed to be deliberate based on a desire to learn and improve understanding of the problem. In addition, a humorous title can merely detract from the seriousness and authority of your research. 
  • Unlike everywhere else in a college-level social sciences research paper [except when using direct quotes in the text], titles do not have to adhere to rigid grammatical or stylistic standards. For example, it could be appropriate to begin a title with a coordinating conjunction [i.e., and, but, or, nor, for, so, yet] if it makes sense to do so and does not detract from the purpose of the study [e.g., "Yet Another Look at Mutual Fund Tournaments"] or beginning the title with an inflected form of a verb such as those ending in -ing [e.g., "Assessing the Political Landscape: Structure, Cognition, and Power in Organizations"].

Appiah, Kingsley Richard et al. “Structural Organisation of Research Article Titles: A Comparative Study of Titles of Business, Gynaecology and Law.” Advances in Language and Literary Studies 10 (2019); Hartley James. “To Attract or to Inform: What are Titles for?” Journal of Technical Writing and Communication 35 (2005): 203-213; Jaakkola, Maarit. “Journalistic Writing and Style.” In Oxford Research Encyclopedia of Communication . Jon F. Nussbaum, editor. (New York: Oxford University Press, 2018): https://oxfordre.com/communication.

Structure and Writing Style

The following parameters can be used to help you formulate a suitable research paper title:

  • The purpose of the research
  • The scope of the research
  • The narrative tone of the paper [typically defined by the type of the research]
  • The methods used to study the problem

The initial aim of a title is to capture the reader’s attention and to highlight the research problem under investigation.

Create a Working Title Typically, the final title you submit to your professor is created after the research is complete so that the title accurately captures what has been done . The working title should be developed early in the research process because it can help anchor the focus of the study in much the same way the research problem does. Referring back to the working title can help you reorient yourself back to the main purpose of the study if you find yourself drifting off on a tangent while writing. The Final Title Effective titles in research papers have several characteristics that reflect general principles of academic writing.

  • Indicate accurately the subject and scope of the study,
  • Rarely use abbreviations or acronyms unless they are commonly known,
  • Use words that create a positive impression and stimulate reader interest,
  • Use current nomenclature from the field of study,
  • Identify key variables, both dependent and independent,
  • Reveal how the paper will be organized,
  • Suggest a relationship between variables which supports the major hypothesis,
  • Is limited to 5 to 15 substantive words,
  • Does not include redundant phrasing, such as, "A Study of," "An Analysis of" or similar constructions,
  • Takes the form of a question or declarative statement,
  • If you use a quote as part of the title, the source of the quote is cited [usually using an asterisk and footnote],
  • Use correct grammar and capitalization with all first words and last words capitalized, including the first word of a subtitle. All nouns, pronouns, verbs, adjectives, and adverbs that appear between the first and last words of the title are also capitalized, and
  • Rarely uses an exclamation mark at the end of the title.

The Subtitle Subtitles are frequently used in social sciences research papers because it helps the reader understand the scope of the study in relation to how it was designed to address the research problem. Think about what type of subtitle listed below reflects the overall approach to your study and whether you believe a subtitle is needed to emphasize the investigative parameters of your research.

1.  Explains or provides additional context , e.g., "Linguistic Ethnography and the Study of Welfare Institutions as a Flow of Social Practices: The Case of Residential Child Care Institutions as Paradoxical Institutions." [Palomares, Manuel and David Poveda.  Text & Talk: An Interdisciplinary Journal of Language, Discourse and Communication Studies 30 (January 2010): 193-212]

2.  Adds substance to a literary, provocative, or imaginative title or quote , e.g., "Listen to What I Say, Not How I Vote": Congressional Support for the President in Washington and at Home." [Grose, Christian R. and Keesha M. Middlemass. Social Science Quarterly 91 (March 2010): 143-167]

3.  Qualifies the geographic scope of the research , e.g., "The Geopolitics of the Eastern Border of the European Union: The Case of Romania-Moldova-Ukraine." [Marcu, Silvia. Geopolitics 14 (August 2009): 409-432]

4.  Qualifies the temporal scope of the research , e.g., "A Comparison of the Progressive Era and the Depression Years: Societal Influences on Predictions of the Future of the Library, 1895-1940." [Grossman, Hal B. Libraries & the Cultural Record 46 (2011): 102-128]

5.  Focuses on investigating the ideas, theories, or work of a particular individual , e.g., "A Deliberative Conception of Politics: How Francesco Saverio Merlino Related Anarchy and Democracy." [La Torre, Massimo. Sociologia del Diritto 28 (January 2001): 75 - 98]

6.  Identifies the methodology used , e.g. "Student Activism of the 1960s Revisited: A Multivariate Analysis Research Note." [Aron, William S. Social Forces 52 (March 1974): 408-414]

7.  Defines the overarching technique for analyzing the research problem , e.g., "Explaining Territorial Change in Federal Democracies: A Comparative Historical Institutionalist Approach." [ Tillin, Louise. Political Studies 63 (August 2015): 626-641.

With these examples in mind, think about what type of subtitle reflects the overall approach to your study. This will help the reader understand the scope of the study in relation to how it was designed to address the research problem.

Anstey, A. “Writing Style: What's in a Title?” British Journal of Dermatology 170 (May 2014): 1003-1004; Balch, Tucker. How to Compose a Title for Your Research Paper. Augmented Trader blog. School of Interactive Computing, Georgia Tech University; Bavdekar, Sandeep B. “Formulating the Right Title for a Research Article.” Journal of Association of Physicians of India 64 (February 2016); Choosing the Proper Research Paper Titles. AplusReports.com, 2007-2012; Eva, Kevin W. “Titles, Abstracts, and Authors.” In How to Write a Paper . George M. Hall, editor. 5th edition. (Oxford: John Wiley and Sons, 2013), pp. 33-41; Hartley James. “To Attract or to Inform: What are Titles for?” Journal of Technical Writing and Communication 35 (2005): 203-213; General Format. The Writing Lab and The OWL. Purdue University; Kerkut G.A. “Choosing a Title for a Paper.” Comparative Biochemistry and Physiology Part A: Physiology 74 (1983): 1; “Tempting Titles.” In Stylish Academic Writing . Helen Sword, editor. (Cambridge, MA: Harvard University Press, 2012), pp. 63-75; Nundy, Samiran, et al. “How to Choose a Title?” In How to Practice Academic Medicine and Publish from Developing Countries? A Practical Guide . Edited by Samiran Nundy, Atul Kakar, and Zulfiqar A. Bhutta. (Springer Singapore, 2022), pp. 185-192.

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6 tips for writing a great title for your research article

how to come up with a good title for research paper

Title is the first thing the reader sees from your research article. Based on the title the reader decides to have a look at the article — or not. So a better title will attract more readers and quite possibly increase the impact of your research. If you wonder what makes a good title, and how you can formulate one for your paper as well, then check out our six tips for writing a great research article title.

Goal: catch the attention of the *right* reader

A good title helps the reader quickly recognize whether this paper is relevant for them. The title should give the reader an accurate picture of the article — and motivate the *right* reader to go on and read the article.

Additionally, an ideal title is memorable : researchers are reading many papers, some will be inevitably forgotten. A good title ensures that your paper will stick in your reader’s mind.

Case study: Important paper missed because of its title

Let me tell you an example from my own research, about an important paper that we missed because of its title.

Article entitled Distinct contributions of Na V 1.6 and Na V 1.2 in action potential initiation and backpropagation has been published in July 2009 in the prestigious journal Nature Neuroscience .

A couple of months later I started to work on a project that later became my PhD thesis. And the above mentioned article turned out to be the most important study on which my whole work was based.

Yet when I started, I didn’t know about the paper. My supervisor and another professor working on similar topics didn’t know about it either.

They had surely seen the title since they were following the journal’s publications. But they didn’t recognize that this might be a relevant paper.

Eventually we learned about the paper from a collaborator from a different institute. Later when I was presenting my work at conferences, I encountered many other researchers who missed this paper, even though it was clearly relevant to them.

So, what’s the issue with this title? Read on my tips on how to write a great title , and learn along the way what is problematic with this title and how we can fix it.

1. Headline the main result, not the main effort

If your paper has a clear main finding that can be summarized in a sentence , put it in the title. Such a title is much more interesting (and informative) than a title describing your approach.

Prof. Kevin Plaxco gives the following examples in his commentary article The art of writing science :

  • Main effort (not optimal): A phylogenetic analysis of humans and chimps
  • Main result (preferred): Phylogenetic evidence indicates an exceptionally close relationship between humans and chimps

Here is another example:

  • Main result missing: Cognitive-behavioural stress management skills and quality of life in stress-related disorders
  • Main result in the title: Cognitive-behavioural stress management skills improve quality of life in stress-related disorders

Concerning our case study example, the title Distinct contributions of Na V 1.6 and Na V 1.2 in action potential initiation and backpropagation does (kind of) contain the main result, albeit it is not formulated as a full sentence. We’ll see later how we can improve it.

Do you need to revise & polish your manuscript or thesis but don’t know where to begin?

Get your Revision Checklist

Click here for an efficient step-by-step revision of your scientific texts.

2. Adapt the level of detail to your target audience

If your article is intended for a broader audience (that is, you want to publish it in a general journal), your title should be more general , so that it is understandable to this broader audience.

On the other hand, if your article is intended for a specialized audience and a specialized journal, you can include more details and jargon in the title.

  • article published in the broad journal Nature: The hippocampus is crucial for forming non-hippocampal long-term memory during sleep
  • article on a similar topic published in the specialized journal Neurobiology of Learning and Memory: Sleep enhances memory consolidation in the hippocampus-dependent object-place recognition task in rats

However, be careful with short and general titles . Such titles are typical for review articles , because they suggest a broad scope of the article. So your readers might mistaken your original research article for a review article.

For example, the title Axon Initial Segment–Associated Microglia sounds like it’s a review, but it is an original research article. Such a title is misleading for the readers, so it’s better to avoid it.

how to come up with a good title for research paper

Not every neuroscientist knows what is “Na V 1.6″ and “Na V 1.2″. My supervisor didn’t know either — and it turns out that this was one of the reasons why he and the other professor missed this article. “Na V 1.6″ and “Na V 1.2″ are sodium channels — and every neuroscientist knows what are those. So the keyword “sodium channels” should definitely be included in an article title published in such a general journal as Nature Neuroscience .

3. Avoid “fluff” at the beginning of the title

Beginning of the title is especially salient , especially visible to the reader. And often this is your only chance to convince your potential reader that this paper is relevant to them.

So it’s a mistake to start the title with “fluff”, that is, a phrase that doesn’t carry much content and can be safely omitted. Instead, begin your title with an important keyword .

For example:

  • Aspects of ​immune dysfunction in end-stage renal disease
  • Revisiting the role of xanthophylls in nonphotochemical quenching

Our case-study title Distinct contributions of Na V 1.6 and Na V 1.2 in action potential initiation and backpropagation does not start with a meaningless phrase that can be simply deleted. However, it also doesn’t start with an important keyword. Let’s see in the next point what would be a better beginning of the title.

4. Use the Context – Emphasis structure

A great title follows the optimal sentence structure : The beginning of the title acts as context for the rest of the title while the end of the title is naturally emphasized (if the reader gets this far).

So a good strategy is to include at the beginning of the title a keyword that will be recognized by all of your target readers and at the end of the title a keyword that is specific to your paper and its contribution.

However, what is a general keyword and what is a specific contribution might depend on your audience .

For example, the title Selective Adsorption to Particular Crystal Faces of ZnO suggests that this article primarily targets researchers interested in adsorption processes: “selective adsorption” is the general process, which is examined in this paper for the particular case of ZnO. However, if the paper targets researchers working on ZnO (zinc oxide), then it would be better to mention “ZnO” at beginning of the title.

Now let’s consider our case study : Distinct contributions of Na V 1.6 and Na V 1.2 in action potential initiation and backpropagation .

how to come up with a good title for research paper

Then, what is a specific keyword related to the contribution of this paper? I would say it could be “Na V 1.6 and Na V 1.2 sodium channels”: although there are some previous studies investigating these two channel types, this paper put all the puzzle pieces together and provided a coherent picture about the interplay of these two channel types in — you guessed it — action potential initiation and backpropagation.

So, let’s improve this title by putting “Action potential initiation and backpropagation” at the beginning and “Na V 1.6 and Na V 1.2 sodium channels” at the end. Then we can rearrange the rest such that it makes sense — and reveals the main message of the paper:

Action potential initiation and backpropagation is differentially regulated by Na V 1.6 and Na V 1.2 sodium channels

A much better title, don’t you think?

5. “Context: Details” structure also works

But what to do with papers that have no single take-home message that can be summarized in a sentence?

For explorative papers that cover several problems or aspects of a topic, the “Context: Details” structure is often suitable. Here, you start with the general contextual keyword(s) that grab the attention of the reader, and then supplement relevant details after the colon.

  • UCB revisited: Improved regret bounds for the stochastic multi-armed bandit problem
  • Single Cell Assay for Molecular Diagnostics and Medicine: Monitoring Intracellular Concentrations of Macromolecules by Two-photon Fluorescence Lifetime Imaging

Here are some examples that don’t work very well:

  • Noise statistics identification for Kalman filtering of the electron radiation belt observations: 2. Filtration and smoothing
  • A better oscillation detection method robustly extracts EEG rhythms across brain state changes: The human alpha rhythm as a test case

In these cases, the first part before the colon is too long, it provides much more information than just the context, and therefore the whole title becomes harder to understand and remember.

So for an effective “Context: Details” type of title, make sure that the first part before the colon is short and memorable . Then the second part after the colon can be longer and detailed, and the title will still create a clear image in reader’s mind.

6. Title as a question or catchy title? It depends…

Now you might ask yourself: can’t we write more interesting titles than those that accurately reflect the content of the paper? These can be pretty boring… What about titles formulated as questions? And “catchy” titles?

Well, the general rule is to follow the conventions of your field . If some of the research articles you are reading have catchy titles, then it’s most probably OK for you to do this as well.

For example, questions and catchy titles are quite common in research articles from psychology:

  • How often is p rep close to the true replication probability?
  • Must interesting things be pleasant? A test of competing appraisal structures.

On the other hand, I have rarely seen a question as a title in a research article from neuroscience.

However, in most fields catchy and even funny titles are appreciated in commentary and opinion articles . For example, the “news & views” commentary article introducing our case-study paper Distinct contributions of Na V 1.6 and Na V 1.2 in action potential initiation and backpropagation is entitled Who let the spikes out?

Also the titles of review articles might be less formal. Which brings us to the next point…

Titles of review articles

Titles of review articles tend to be more general and broad than titles of original research articles. This, of course, reflects the broader scope and content of review articles. For example:

  • Carbohydrate inhibitors of cholera toxin
  • Neural circuits underlying thirst and fluid homeostasis

These titles don’t consist of a full sentence — because there is rarely a main take-home message in a review article. However, what is helpful here is to follow the Context-Emphasis structure introduced in point 4.

Titles of review articles often include the word “review” in the title, for example:

  • Gap junctions in developing neocortex: a review
  • A systematic review of COVID-19 epidemiology based on current evidence

And as we said in the previous point, titles of review articles may be less formal and more catchy even in fields where such titles are not used for original research articles:

  • Spooky sodium balance
  • Remembering the past to imagine the future: the prospective brain

How to find the perfect title for your article

Now you have learned all the rules for good titles, but one question remains: How to proceed? How to come up with a great title for your article?

how to come up with a good title for research paper

Then I recommend the following procedure :

  • First, generate 10 possible titles . These 10 titles don’t have to be unique: some of them might only differ in one or two words or in the word order.
  • Next, select the best title . You can do this together with your co-authors. Or each co-author picks one or two favorites and then you discuss and select the final title together.

With this procedure it’s much easier to find the most suitable title for your paper than if you would create just one title and then try to improve it.

So that was quite some theory about how to write a great title. Now if you want to practice this new knowledge, here is a little exercise for you.

What is good and what is not optimal about these titles? How would you improve them?

  • Analysis of processes leading to localized electron enhancements in the outer radiation belt
  • Wild-type and cancer-related p53 proteins are preferentially degraded by MDM2 as dimers rather than tetramers
  • A New Murine Model to Define the Critical Pathologic and Therapeutic Mediators of Polymyositis

If you are currently writing a manuscript and would like to get feedback and suggestions for your title: please, feel free to post it as a comment . Alternatively, you can also ask for feedback in our Facebook group Academic writing — peer feedback .

Do you need to revise & polish your manuscript or thesis but don’t know where to begin? Is your text a mess and you don't know how to improve it?

Click here for an efficient step-by-step revision of your scientific texts. You will be guided through each step with concrete tips for execution.

3 thoughts on “ 6 tips for writing a great title for your research article ”

Dear Martina,

Thank you very much for another portion of valuable information! It’s really helpful!

I’d be very greatful if you could comment on a title for a review article I’m writting now. Which of the two title you think is better:

Novel approaches to epigenetic therapies Novel approaches to epigenetic therapies: from drug combinations to epigenetic editing

Thank you for your suggestion, Kind regards, Aleksandra

Dear Aleksandra,

I am happy to hear that you found the article helpful!

Concerning your question: I prefer the second, longer title. It gives the reader a much better idea of what your review article is about. “Novel approaches to epigenetic therapies” alone is rather unspecific…

All the best, Martina

That was my choice as well! Thank you for ensuring me about it!

All the best, Aleksandra

Comments are closed.

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How to Write a Research Paper Title

7 Tips to create the best research title for your paper

Knowing how to write a research paper title is an art that not every researcher possesses, and researchers often spend a lot of time skimming through articles to find the right research paper title.

According to an interesting estimate, researchers read more than 100 publications every year and spend long hours, weeks and months searching for and reading articles relevant to their field of study. 1 While open access publishing and online repositories have made it easier to find articles, researchers still need to browse through a sea of research, often using research paper titles, to find relevant information for their research study. Researchers also face the challenge of ensuring their work reaches a broader audience in order to get more citations. This is where the importance of a good title for a research paper becomes evident.

Your research paper title is one of the first things readers in your research paper and plays an important role in influencing whether they will actually go through the entire article. This makes it critical to have a good research paper title that captures the reader’s attention. In this article, we look at the key characteristics of a good research title and what to keep in mind to create a research title that works for you.

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What to keep in mind when writing a research paper title

  • Convey the key research findings: Before writing a research paper title, list down what your study is about, what you have achieved or discovered, and the methodology used. Try and identify the one or two key elements that make your study novel or significant in your subject area. Combine these elements to create the best research title that showcases your article accurately and effectively.
  • Choose a declarative research paper title : Declarative titles are more informative and help readers to quickly grasp what the body of the article may contain. Therefore, it is considered to be more impactful and more likely to attract the reader’s attention. Additionally, most editors agree that papers with declarative titles are more likely to be shared online, allowing researchers to reach a far wider audience. 2
  • A good research title must pique reader interest : Researchers browsing through online platforms during their literature search often spend only a few seconds to read the title and evaluate an article’s relevance. This makes it important to create a catchy title for your research paper that will spark curiosity in the minds of your audience, which may prompt them pause, read, share, and discuss your research paper.
  • Avoid making any unsubstantiated claims: This is an important aspect to keep in mind when creating research paper titles. While it may be tempting to write titles with claims that will immediately attract reader attention and get you more citations, your research should be able to back-up these claims with substantive, studied evidence. Failing to do so can create mistrust about the research and even hurt your reputation.
  • Keep it simple and avoid jargon: It’s tempting to use technical words in a research paper title when you know that your primary audience is most likely to be other researchers working in the same field. However, this can prove counter-productive as readers who are not familiar with these complicated words may end up skipping your article. Some early career researchers might also give your paper a pass as they may feel that it is too technical for them so avoid using jargon.

Let Paperpal generate a suitable title for your content in minutes. Try it now!

  • Use phrases to keep your research title concise: One mistake early career researchers make is using full sentences to write the research paper title. Avoid complex phrases and unnecessary details as it makes the title unnecessarily lengthy. Remember to ensure proper syntax when trying to rephrase the title to make it leaner. A good research paper title offers a concise summary of the paper’s content; keep your title to under 12 words as lengthy titles can be hard to understand and may seem unfocused and uninteresting.
  • Include keywords to make your article discoverable: Today most researchers turn to online databases and search engines like Google Scholar to find the right research. This makes it critical to identify and use the best keywords for your research subject/topic when creating a research title. The best research paper title is one that is easily discoverable, making it easy for your readers to find and read your article.

A review of more than 150,000 papers  submitted to UK’s Research Excellence Framework (REF) database found that the style of a research paper’s title impacted the number of citations it would typically receive. 3 Writing a good research paper title is worth the time and effort, and we’re sure the points listed above will help!

How to generate research paper titles with Paperpal?

A research paper title is the first impression for journal editors, reviewers, and readers to understand the aim and purpose of your research study. However, picking a research paper title that encapsulates your research’s content can be daunting. Your research paper title should accurately capture your work, contain highly searched keywords, and should also sound interesting to people who work on a similar topic.   

Paperpal’s secure generative AI helps you write research paper titles twice as fast, ensuring they align with your research topic. Follow these simple steps to create an impactful research paper title: 

  • Sign Up or Log In: Start by creating an account or logging into Paperpal . 
  • Paste your content: Once logged in, paste your research paper’s content or abstract onto the document. 
  • Generate your title: Click on ‘Templates’ in the side navigation pane, go to Titles, and select ‘Generate’ . 

Paperpal will analyze your content and propose a fitting research paper title. If it doesn’t quite hit the mark, simply click regenerate to get additional title options until you find the perfect one. Remember, while Paperpal provides a solid starting point, personalizing the title to capture the essence of your research is key to making it stand out.  

  • How Scientists Retrieve Publications: An Empirical Study of How the Internet Is Overtaking Paper Media. Journal of Electronic Publishing, December 2000. [Accessed November 3, 2022] Available at https://quod.lib.umich.edu/j/jep/3336451.0006.202?view=text;rgn=main
  • Di Girolamo, N. Health care articles with simple and declarative titles were more likely to be in the Altmetric Top 100. Journal of Clinical Epidemiology, December 2016. [Accessed November 3, 2022] Available at https://www.jclinepi.com/article/S0895-4356(16)30853-8/fulltext
  • Hudson, J. An analysis of the titles of papers submitted to the UK REF in 2014: authors, disciplines, and stylistic details. Scientometrics, July 2016. [Accessed November 3, 2022] Available at https://link.springer.com/article/10.1007/s11192-016-2081-4

Frequently Asked Questions (FAQs)

It is generally recommended to avoid using a question to write a good research paper title. Titles should be concise and informative, conveying the main focus of the study. While questions can be used in the introduction or research objectives, a clear and declarative title is preferred to accurately represent the content and purpose of the research.

A research paper title should be concise and to the point. Ideally, it should be around 10 to 12 words or less. A shorter title is more effective in grabbing readers’ attention and conveying the main idea succinctly. However, it’s important to ensure that the title still accurately represents the research and provides enough information for readers to understand the scope of the study.

Including specific keywords related to the research topic can be beneficial. Keywords help in indexing and searching for relevant papers. However, it is not necessary to include all keywords in the title. Instead, focus on incorporating essential and relevant keywords that reflect the core aspects of the study. Use keywords that are commonly used and recognized in the field to increase the discoverability and relevance of your research.

Abbreviations or acronyms should generally be avoided in the research paper title. The title should be clear and easily understandable to a broad audience. If an abbreviation is commonly used in the field and is essential to convey the research focus, it can be included, but it’s important to provide the full term upon its first mention in the paper for clarity.

Whether you can change the research paper title after submission depends on the specific guidelines and policies of the journal or conference. Some publications allow minor revisions, including title changes, during the review process. However, it is best to ensure that the title is carefully chosen and reviewed before submission. If a change is necessary, it is recommended to contact the editor or conference organizers for guidance on whether it’s permissible to modify the title.

The preferred formatting style for research paper titles varies depending on the specific guidelines of the target journal or conference. Generally, sentence case is commonly used, where only the first word and proper nouns are capitalized. However, some publications may prefer title case, where the first letter of each major word is capitalized. It is important to carefully review the submission guidelines or consult the specific style guide recommended by the publication to ensure consistency with their preferred formatting style.

Paperpal is a comprehensive AI writing toolkit that helps students and researchers achieve 2x the writing in half the time. It leverages 21+ years of STM experience and insights from millions of research articles to provide in-depth academic writing, language editing, and submission readiness support to help you write better, faster.  

Get accurate academic translations, rewriting support, grammar checks, vocabulary suggestions, and generative AI assistance that delivers human precision at machine speed. Try for free or upgrade to Paperpal Prime starting at US$19 a month to access premium features, including consistency, plagiarism, and 30+ submission readiness checks to help you succeed.  

Experience the future of academic writing – Sign up to Paperpal and start writing for free!  

Related Reads:

How to write a research paper outline: simple steps for researchers.

  • Manuscript Withdrawal: Reasons, Consequences, and How to Withdraw Submitted Manuscripts
  • Supplementary Materials in Research: 5 Tips for Authors
  • What is an Expository Essay and How to Write It

The Ethics of Using AI in Research and Scientific Writing

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Writing the title and abstract for a research paper: Being concise, precise, and meticulous is the key

Milind s. tullu.

Department of Pediatrics, Seth G.S. Medical College and KEM Hospital, Parel, Mumbai, Maharashtra, India

This article deals with formulating a suitable title and an appropriate abstract for an original research paper. The “title” and the “abstract” are the “initial impressions” of a research article, and hence they need to be drafted correctly, accurately, carefully, and meticulously. Often both of these are drafted after the full manuscript is ready. Most readers read only the title and the abstract of a research paper and very few will go on to read the full paper. The title and the abstract are the most important parts of a research paper and should be pleasant to read. The “title” should be descriptive, direct, accurate, appropriate, interesting, concise, precise, unique, and should not be misleading. The “abstract” needs to be simple, specific, clear, unbiased, honest, concise, precise, stand-alone, complete, scholarly, (preferably) structured, and should not be misrepresentative. The abstract should be consistent with the main text of the paper, especially after a revision is made to the paper and should include the key message prominently. It is very important to include the most important words and terms (the “keywords”) in the title and the abstract for appropriate indexing purpose and for retrieval from the search engines and scientific databases. Such keywords should be listed after the abstract. One must adhere to the instructions laid down by the target journal with regard to the style and number of words permitted for the title and the abstract.

Introduction

This article deals with drafting a suitable “title” and an appropriate “abstract” for an original research paper. Because the “title” and the “abstract” are the “initial impressions” or the “face” of a research article, they need to be drafted correctly, accurately, carefully, meticulously, and consume time and energy.[ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ] Often, these are drafted after the complete manuscript draft is ready.[ 2 , 3 , 4 , 5 , 9 , 10 , 11 ] Most readers will read only the title and the abstract of a published research paper, and very few “interested ones” (especially, if the paper is of use to them) will go on to read the full paper.[ 1 , 2 ] One must remember to adhere to the instructions laid down by the “target journal” (the journal for which the author is writing) regarding the style and number of words permitted for the title and the abstract.[ 2 , 4 , 5 , 7 , 8 , 9 , 12 ] Both the title and the abstract are the most important parts of a research paper – for editors (to decide whether to process the paper for further review), for reviewers (to get an initial impression of the paper), and for the readers (as these may be the only parts of the paper available freely and hence, read widely).[ 4 , 8 , 12 ] It may be worth for the novice author to browse through titles and abstracts of several prominent journals (and their target journal as well) to learn more about the wording and styles of the titles and abstracts, as well as the aims and scope of the particular journal.[ 5 , 7 , 9 , 13 ]

The details of the title are discussed under the subheadings of importance, types, drafting, and checklist.

Importance of the title

When a reader browses through the table of contents of a journal issue (hard copy or on website), the title is the “ first detail” or “face” of the paper that is read.[ 2 , 3 , 4 , 5 , 6 , 13 ] Hence, it needs to be simple, direct, accurate, appropriate, specific, functional, interesting, attractive/appealing, concise/brief, precise/focused, unambiguous, memorable, captivating, informative (enough to encourage the reader to read further), unique, catchy, and it should not be misleading.[ 1 , 2 , 3 , 4 , 5 , 6 , 9 , 12 ] It should have “just enough details” to arouse the interest and curiosity of the reader so that the reader then goes ahead with studying the abstract and then (if still interested) the full paper.[ 1 , 2 , 4 , 13 ] Journal websites, electronic databases, and search engines use the words in the title and abstract (the “keywords”) to retrieve a particular paper during a search; hence, the importance of these words in accessing the paper by the readers has been emphasized.[ 3 , 4 , 5 , 6 , 12 , 14 ] Such important words (or keywords) should be arranged in appropriate order of importance as per the context of the paper and should be placed at the beginning of the title (rather than the later part of the title, as some search engines like Google may just display only the first six to seven words of the title).[ 3 , 5 , 12 ] Whimsical, amusing, or clever titles, though initially appealing, may be missed or misread by the busy reader and very short titles may miss the essential scientific words (the “keywords”) used by the indexing agencies to catch and categorize the paper.[ 1 , 3 , 4 , 9 ] Also, amusing or hilarious titles may be taken less seriously by the readers and may be cited less often.[ 4 , 15 ] An excessively long or complicated title may put off the readers.[ 3 , 9 ] It may be a good idea to draft the title after the main body of the text and the abstract are drafted.[ 2 , 3 , 4 , 5 ]

Types of titles

Titles can be descriptive, declarative, or interrogative. They can also be classified as nominal, compound, or full-sentence titles.

Descriptive or neutral title

This has the essential elements of the research theme, that is, the patients/subjects, design, interventions, comparisons/control, and outcome, but does not reveal the main result or the conclusion.[ 3 , 4 , 12 , 16 ] Such a title allows the reader to interpret the findings of the research paper in an impartial manner and with an open mind.[ 3 ] These titles also give complete information about the contents of the article, have several keywords (thus increasing the visibility of the article in search engines), and have increased chances of being read and (then) being cited as well.[ 4 ] Hence, such descriptive titles giving a glimpse of the paper are generally preferred.[ 4 , 16 ]

Declarative title

This title states the main finding of the study in the title itself; it reduces the curiosity of the reader, may point toward a bias on the part of the author, and hence is best avoided.[ 3 , 4 , 12 , 16 ]

Interrogative title

This is the one which has a query or the research question in the title.[ 3 , 4 , 16 ] Though a query in the title has the ability to sensationalize the topic, and has more downloads (but less citations), it can be distracting to the reader and is again best avoided for a research article (but can, at times, be used for a review article).[ 3 , 6 , 16 , 17 ]

From a sentence construct point of view, titles may be nominal (capturing only the main theme of the study), compound (with subtitles to provide additional relevant information such as context, design, location/country, temporal aspect, sample size, importance, and a provocative or a literary; for example, see the title of this review), or full-sentence titles (which are longer and indicate an added degree of certainty of the results).[ 4 , 6 , 9 , 16 ] Any of these constructs may be used depending on the type of article, the key message, and the author's preference or judgement.[ 4 ]

Drafting a suitable title

A stepwise process can be followed to draft the appropriate title. The author should describe the paper in about three sentences, avoiding the results and ensuring that these sentences contain important scientific words/keywords that describe the main contents and subject of the paper.[ 1 , 4 , 6 , 12 ] Then the author should join the sentences to form a single sentence, shorten the length (by removing redundant words or adjectives or phrases), and finally edit the title (thus drafted) to make it more accurate, concise (about 10–15 words), and precise.[ 1 , 3 , 4 , 5 , 9 ] Some journals require that the study design be included in the title, and this may be placed (using a colon) after the primary title.[ 2 , 3 , 4 , 14 ] The title should try to incorporate the Patients, Interventions, Comparisons and Outcome (PICO).[ 3 ] The place of the study may be included in the title (if absolutely necessary), that is, if the patient characteristics (such as study population, socioeconomic conditions, or cultural practices) are expected to vary as per the country (or the place of the study) and have a bearing on the possible outcomes.[ 3 , 6 ] Lengthy titles can be boring and appear unfocused, whereas very short titles may not be representative of the contents of the article; hence, optimum length is required to ensure that the title explains the main theme and content of the manuscript.[ 4 , 5 , 9 ] Abbreviations (except the standard or commonly interpreted ones such as HIV, AIDS, DNA, RNA, CDC, FDA, ECG, and EEG) or acronyms should be avoided in the title, as a reader not familiar with them may skip such an article and nonstandard abbreviations may create problems in indexing the article.[ 3 , 4 , 5 , 6 , 9 , 12 ] Also, too much of technical jargon or chemical formulas in the title may confuse the readers and the article may be skipped by them.[ 4 , 9 ] Numerical values of various parameters (stating study period or sample size) should also be avoided in the titles (unless deemed extremely essential).[ 4 ] It may be worthwhile to take an opinion from a impartial colleague before finalizing the title.[ 4 , 5 , 6 ] Thus, multiple factors (which are, at times, a bit conflicting or contrasting) need to be considered while formulating a title, and hence this should not be done in a hurry.[ 4 , 6 ] Many journals ask the authors to draft a “short title” or “running head” or “running title” for printing in the header or footer of the printed paper.[ 3 , 12 ] This is an abridged version of the main title of up to 40–50 characters, may have standard abbreviations, and helps the reader to navigate through the paper.[ 3 , 12 , 14 ]

Checklist for a good title

Table 1 gives a checklist/useful tips for drafting a good title for a research paper.[ 1 , 2 , 3 , 4 , 5 , 6 , 12 ] Table 2 presents some of the titles used by the author of this article in his earlier research papers, and the appropriateness of the titles has been commented upon. As an individual exercise, the reader may try to improvise upon the titles (further) after reading the corresponding abstract and full paper.

Checklist/useful tips for drafting a good title for a research paper

Some titles used by author of this article in his earlier publications and remark/comment on their appropriateness

The Abstract

The details of the abstract are discussed under the subheadings of importance, types, drafting, and checklist.

Importance of the abstract

The abstract is a summary or synopsis of the full research paper and also needs to have similar characteristics like the title. It needs to be simple, direct, specific, functional, clear, unbiased, honest, concise, precise, self-sufficient, complete, comprehensive, scholarly, balanced, and should not be misleading.[ 1 , 2 , 3 , 7 , 8 , 9 , 10 , 11 , 13 , 17 ] Writing an abstract is to extract and summarize (AB – absolutely, STR – straightforward, ACT – actual data presentation and interpretation).[ 17 ] The title and abstracts are the only sections of the research paper that are often freely available to the readers on the journal websites, search engines, and in many abstracting agencies/databases, whereas the full paper may attract a payment per view or a fee for downloading the pdf copy.[ 1 , 2 , 3 , 7 , 8 , 10 , 11 , 13 , 14 ] The abstract is an independent and stand-alone (that is, well understood without reading the full paper) section of the manuscript and is used by the editor to decide the fate of the article and to choose appropriate reviewers.[ 2 , 7 , 10 , 12 , 13 ] Even the reviewers are initially supplied only with the title and the abstract before they agree to review the full manuscript.[ 7 , 13 ] This is the second most commonly read part of the manuscript, and therefore it should reflect the contents of the main text of the paper accurately and thus act as a “real trailer” of the full article.[ 2 , 7 , 11 ] The readers will go through the full paper only if they find the abstract interesting and relevant to their practice; else they may skip the paper if the abstract is unimpressive.[ 7 , 8 , 9 , 10 , 13 ] The abstract needs to highlight the selling point of the manuscript and succeed in luring the reader to read the complete paper.[ 3 , 7 ] The title and the abstract should be constructed using keywords (key terms/important words) from all the sections of the main text.[ 12 ] Abstracts are also used for submitting research papers to a conference for consideration for presentation (as oral paper or poster).[ 9 , 13 , 17 ] Grammatical and typographic errors reflect poorly on the quality of the abstract, may indicate carelessness/casual attitude on part of the author, and hence should be avoided at all times.[ 9 ]

Types of abstracts

The abstracts can be structured or unstructured. They can also be classified as descriptive or informative abstracts.

Structured and unstructured abstracts

Structured abstracts are followed by most journals, are more informative, and include specific subheadings/subsections under which the abstract needs to be composed.[ 1 , 7 , 8 , 9 , 10 , 11 , 13 , 17 , 18 ] These subheadings usually include context/background, objectives, design, setting, participants, interventions, main outcome measures, results, and conclusions.[ 1 ] Some journals stick to the standard IMRAD format for the structure of the abstracts, and the subheadings would include Introduction/Background, Methods, Results, And (instead of Discussion) the Conclusion/s.[ 1 , 2 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 17 , 18 ] Structured abstracts are more elaborate, informative, easy to read, recall, and peer-review, and hence are preferred; however, they consume more space and can have same limitations as an unstructured abstract.[ 7 , 9 , 18 ] The structured abstracts are (possibly) better understood by the reviewers and readers. Anyway, the choice of the type of the abstract and the subheadings of a structured abstract depend on the particular journal style and is not left to the author's wish.[ 7 , 10 , 12 ] Separate subheadings may be necessary for reporting meta-analysis, educational research, quality improvement work, review, or case study.[ 1 ] Clinical trial abstracts need to include the essential items mentioned in the CONSORT (Consolidated Standards Of Reporting Trials) guidelines.[ 7 , 9 , 14 , 19 ] Similar guidelines exist for various other types of studies, including observational studies and for studies of diagnostic accuracy.[ 20 , 21 ] A useful resource for the above guidelines is available at www.equator-network.org (Enhancing the QUAlity and Transparency Of health Research). Unstructured (or non-structured) abstracts are free-flowing, do not have predefined subheadings, and are commonly used for papers that (usually) do not describe original research.[ 1 , 7 , 9 , 10 ]

The four-point structured abstract: This has the following elements which need to be properly balanced with regard to the content/matter under each subheading:[ 9 ]

Background and/or Objectives: This states why the work was undertaken and is usually written in just a couple of sentences.[ 3 , 7 , 8 , 9 , 10 , 12 , 13 ] The hypothesis/study question and the major objectives are also stated under this subheading.[ 3 , 7 , 8 , 9 , 10 , 12 , 13 ]

Methods: This subsection is the longest, states what was done, and gives essential details of the study design, setting, participants, blinding, sample size, sampling method, intervention/s, duration and follow-up, research instruments, main outcome measures, parameters evaluated, and how the outcomes were assessed or analyzed.[ 3 , 7 , 8 , 9 , 10 , 12 , 13 , 14 , 17 ]

Results/Observations/Findings: This subheading states what was found, is longer, is difficult to draft, and needs to mention important details including the number of study participants, results of analysis (of primary and secondary objectives), and include actual data (numbers, mean, median, standard deviation, “P” values, 95% confidence intervals, effect sizes, relative risks, odds ratio, etc.).[ 3 , 7 , 8 , 9 , 10 , 12 , 13 , 14 , 17 ]

Conclusions: The take-home message (the “so what” of the paper) and other significant/important findings should be stated here, considering the interpretation of the research question/hypothesis and results put together (without overinterpreting the findings) and may also include the author's views on the implications of the study.[ 3 , 7 , 8 , 9 , 10 , 12 , 13 , 14 , 17 ]

The eight-point structured abstract: This has the following eight subheadings – Objectives, Study Design, Study Setting, Participants/Patients, Methods/Intervention, Outcome Measures, Results, and Conclusions.[ 3 , 9 , 18 ] The instructions to authors given by the particular journal state whether they use the four- or eight-point abstract or variants thereof.[ 3 , 14 ]

Descriptive and Informative abstracts

Descriptive abstracts are short (75–150 words), only portray what the paper contains without providing any more details; the reader has to read the full paper to know about its contents and are rarely used for original research papers.[ 7 , 10 ] These are used for case reports, reviews, opinions, and so on.[ 7 , 10 ] Informative abstracts (which may be structured or unstructured as described above) give a complete detailed summary of the article contents and truly reflect the actual research done.[ 7 , 10 ]

Drafting a suitable abstract

It is important to religiously stick to the instructions to authors (format, word limit, font size/style, and subheadings) provided by the journal for which the abstract and the paper are being written.[ 7 , 8 , 9 , 10 , 13 ] Most journals allow 200–300 words for formulating the abstract and it is wise to restrict oneself to this word limit.[ 1 , 2 , 3 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 22 ] Though some authors prefer to draft the abstract initially, followed by the main text of the paper, it is recommended to draft the abstract in the end to maintain accuracy and conformity with the main text of the paper (thus maintaining an easy linkage/alignment with title, on one hand, and the introduction section of the main text, on the other hand).[ 2 , 7 , 9 , 10 , 11 ] The authors should check the subheadings (of the structured abstract) permitted by the target journal, use phrases rather than sentences to draft the content of the abstract, and avoid passive voice.[ 1 , 7 , 9 , 12 ] Next, the authors need to get rid of redundant words and edit the abstract (extensively) to the correct word count permitted (every word in the abstract “counts”!).[ 7 , 8 , 9 , 10 , 13 ] It is important to ensure that the key message, focus, and novelty of the paper are not compromised; the rationale of the study and the basis of the conclusions are clear; and that the abstract is consistent with the main text of the paper.[ 1 , 2 , 3 , 7 , 9 , 11 , 12 , 13 , 14 , 17 , 22 ] This is especially important while submitting a revision of the paper (modified after addressing the reviewer's comments), as the changes made in the main (revised) text of the paper need to be reflected in the (revised) abstract as well.[ 2 , 10 , 12 , 14 , 22 ] Abbreviations should be avoided in an abstract, unless they are conventionally accepted or standard; references, tables, or figures should not be cited in the abstract.[ 7 , 9 , 10 , 11 , 13 ] It may be worthwhile not to rush with the abstract and to get an opinion by an impartial colleague on the content of the abstract; and if possible, the full paper (an “informal” peer-review).[ 1 , 7 , 8 , 9 , 11 , 17 ] Appropriate “Keywords” (three to ten words or phrases) should follow the abstract and should be preferably chosen from the Medical Subject Headings (MeSH) list of the U.S. National Library of Medicine ( https://meshb.nlm.nih.gov/search ) and are used for indexing purposes.[ 2 , 3 , 11 , 12 ] These keywords need to be different from the words in the main title (the title words are automatically used for indexing the article) and can be variants of the terms/phrases used in the title, or words from the abstract and the main text.[ 3 , 12 ] The ICMJE (International Committee of Medical Journal Editors; http://www.icmje.org/ ) also recommends publishing the clinical trial registration number at the end of the abstract.[ 7 , 14 ]

Checklist for a good abstract

Table 3 gives a checklist/useful tips for formulating a good abstract for a research paper.[ 1 , 2 , 3 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 17 , 22 ]

Checklist/useful tips for formulating a good abstract for a research paper

Concluding Remarks

This review article has given a detailed account of the importance and types of titles and abstracts. It has also attempted to give useful hints for drafting an appropriate title and a complete abstract for a research paper. It is hoped that this review will help the authors in their career in medical writing.

Financial support and sponsorship

Conflicts of interest.

There are no conflicts of interest.

Acknowledgement

The author thanks Dr. Hemant Deshmukh - Dean, Seth G.S. Medical College & KEM Hospital, for granting permission to publish this manuscript.

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What is a "good" title?

"title checklist" from: how to write a good scientific paper. chris a. mack. spie. 2018., other hints for writing a title.

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The title will be read by many people. Only a few will read the entire paper, therefore all words in the title should be chosen with care. Too short a title is not helpful to the potential reader. However too long a title can sometimes be even less meaningful. Remember a title is not an abstract. Also a title is not a sentence.

Goals: • Fewest possible words that describe the contents of the paper. • Avoid waste words like "Studies on", or "Investigations on" • Use specific terms rather than general • Watch your word order and syntax • Avoid abbreviations and jargon

 The title should be clear and informative, and should reflect the aim and approach of the work.

 The title should be as specific as possible while still describing the full range of the work. Does the title, seen in isolation, give a full yet concise and specific indication of the work reported?

 Do not mention results or conclusions in the title.

 Avoid: overly clever or punny titles that will not fare well with search engines or international audiences; titles that are too short to be descriptive or too long to be read; jargon, acronyms, or trademarked terms. 

  • Whenever possible, use a declarative rather than a neutral title
  • Don't end your title with a question mark?
  • Begin with the keywords
  • Use verbs instead of abstract nouns
  • Avoid abbrev. in the title

From: How to Write and Illustrate a Scientific Paper (2008)

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choosing a title

Choosing a Title

Choosing a strong title for your paper is important as the title is the most read part of the paper and it is usually read first. There are two approaches to creating titles, one that is more informative, and another that is more creative. The first is most often used for academic papers, though some disciplines allow for more creatively titled papers. This guide focuses on the informative type.

  • General Tips

Strong titles for academic papers contain the fewest possible words that describe the contents and/or purpose of your research paper. In general, the answers to the following questions can help you create a title for your paper:

  • What is the purpose of this research?
  • What is the scope of this research?
  • What methods were used in this study?
  • Is there something new or exciting about your topic?

Tip: Don't wait until you are done writing your paper to come up with a title. A good title can help you stay focused in your writing just like a good thesis statement can.

Subtitles are sometimes used in academic research papers and are more common among the social science disciplines. 

You may want to include a subtitle in order to:

  • Explain or provide additional context
  • Add substance to a literary, provocative, or imaginative title
  • Qualify the geographic scope of the research
  • Qualify the temporal scope of the research
  • Focus on investigating the ideas, theories, or work of a particular individual

General Tips for creating a strong title: 

  • Indicate accurately the subject and scope of the study
  • Rarely use abbreviations or acronyms unless they are commonly known
  • Use words that create a positive impression and stimulate reader interest
  • Use current nomenclature from the field of study
  • Identify key variables, both dependent and independent
  • Suggest a relationship between variables which supports the major hypothesis
  • Limit to 5 to 15 substantive words
  • Do not include redundant phrasing, such as, "A Study of," "An Analysis of" or similar constructions
  • Use a question or declarative statement
  • Use correct grammar, capitalization, and check publication style for additional parameters 
  • Do not use an exclamation mark at the end of the title

Examples of strong titles for academic papers: 

  • The Effects of Light and Temperature on the Growth of Populations of the Bacterium, Escherichia coli
  • Listen to What I Say, Not How I Vote: Congressional Support for the President in Washington and at Home
  • The Geopolitics of the Eastern Border of the European Union: The Case of Romania-Moldova-Ukraine
  • The Machine-Language of the Muscles: Reading, Sport and the Self in Infinite Jest
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Organizing Academic Research Papers: Choosing a Title

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The title summarizes the main idea or ideas of your study. A good title contains the fewest possible words that adequately describe the contents and/or purpose of your research paper.

The title is without doubt the part of a paper that is read the most, and it is usually read first . If the title is too long it usually contains too many unnecessary words, e.g., "A Study to Investigate the...." On the other hand, a title which is too short often uses words which are too general. For example, "African Politics" could be the title of a book, but it does not provide any information on the focus of a research paper.

Structure and Writing Style

The following parameters can be used to help you formulate a suitable research paper title:

  • The purpose of the research
  • The narrative tone of the paper [typically defined by the type of the research]
  • The methods used

The initial aim of a title is to capture the reader’s attention and to draw his or her attention to the research problem being investigated.

Create a Working Title Typically, the final title you submit to your professor is created after the research is complete so that the title accurately captures what was done . The working title should be developed early in the research process because it can help anchor the focus of the study in much the same way the research problem does. Referring back to the working title can help you reorient yourself back to the main purpose of the study if you feel yourself drifting off on a tangent while writing. The Final Title Effective titles in academic research papers have several characteristics.

  • Indicate accurately the subject and scope of the study.
  • Avoid using abbreviations.
  • Use words that create a positive impression and stimulate reader interest.
  • Use current nomenclature from the field of study.
  • Identify key variables, both dependent and independent.
  • May reveal how the paper will be organized.
  • Suggest a relationship between variables which supports the major hypothesis.
  • Is limited to 10 to 15 substantive words.
  • Do not include "study of," "analysis of" or similar constructions.
  • Titles are usually in the form of a phrase, but can also be in the form of a question.
  • Use correct grammar and capitalization with all first words and last words capitalized, including the first word of a subtitle. All nouns,  pronouns, verbs, adjectives, and adverbs that appear between the first and last words of the title are also capitalized.
  • In academic papers, rarely is a title followed by an exclamation mark. However, a title or subtitle can be in the form of a question.

The Subtitle Subtitles are quite common in social science research papers. Examples of why you may include a subtitle:

  • Explains or provides additional context , e.g., "Linguistic Ethnography and the Study of Welfare Institutions as a Flow of Social Practices: The Case of Residential Child Care Institutions as Paradoxical Institutions."
  • Adds substance to a literary, provocative, or imaginative title , e.g., "Listen to What I Say, Not How I Vote: Congressional Support for the President in Washington and at Home."
  • Qualifies the geographic scope of the research , e.g., "The Geopolitics of the Eastern Border of the European Union: The Case of Romania-Moldova-Ukraine."
  • Qualifies the temporal scope of the research , e.g., "A Comparison of the Progressive Era and the Depression Years: Societal Influences on Predictions of the Future of the Library, 1895-1940."
  • Focuses on investigating the ideas, theories, or work of a particular individual , e.g., "A Deliberative Conception of Politics: How Francesco Saverio Merlino Related Anarchy and Democracy."

Balch, Tucker. How to Compose a Title for Your Research Paper . Augmented Trader blog. School of Interactive Computing, Georgia Tech University;  Choosing the Proper Research Paper Titles . AplusReports.com, 2007-2012; General Format. The Writing Lab and The OWL. Purdue University.

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How to Come up With a Good Title

Last Updated: May 17, 2024 Fact Checked

This article was co-authored by Rachel Scoggins, PhD . Rachel Scoggins is a Visiting Assistant Professor of English at Lander University. Rachel's work has been presented at the South Atlantic Modern Language Association and the Georgia International Conference on Information Literacy. She received her PhD in Literary Studies from Georgia State University in 2016. There are 10 references cited in this article, which can be found at the bottom of the page. This article has been fact-checked, ensuring the accuracy of any cited facts and confirming the authority of its sources. This article has been viewed 577,222 times.

Writing an essay or a story can seem like the hardest part of the project, but sometimes coming up with a catchy title can be just as challenging. However, with a combination of organization and creativity, you can create a wide selection of potential titles that will allow you to choose the perfect one for your work.

Things You Should Know

  • For non-fiction titles, try combining 2 elements, like a quote and a main theme, with a colon between them.
  • For fiction titles, jot down keywords about the main topic and characters. Arrange keywords in different combinations until you find something that you like.
  • Use strong, vivid language to make your title stand out from the crowd.

Writing a Title for Non-Fiction

Step 1 Write a draft of your essay.

  • Essays often change during the drafting and revising process. A title you come up with at the beginning may not reflect your essay when you have finished it. Make sure to also revise your title after you finish your paper.

Step 2 Identify major themes in your work.

  • Look at your thesis statement. This sentence contains the major argument of your paper and can help you craft a title.
  • Look at your topic sentences. Reading these sentences together can help you pick out themes, symbols, or motifs in your paper that can be integrated into the title.
  • Consider asking a friend to read your work to help you identify themes.

Step 3 Determine your target audience.

  • If you are writing a school assignment, or your audience are academics and specialists in your topic, use formal language. Avoid using a playful tone or slang terms.
  • If you are trying to reach an online audience, think of what keywords a reader might use to find your article. For example, if you wrote a how-to article, include words like "beginner" or "do it yourself" that would identify your writing as appropriate for all levels of ability.
  • If your piece is a news story, consider who you are writing about. For example, if are writing about an athletic team write down terms like "fan," "coach," "referee," or the team name. Readers with an interest in sports or that team can quickly identify your perspective and the topic of your story.

Step 4 Think about the function of a title.

  • Declarative titles state the main findings or conclusions.
  • Descriptive titles describe the subject of the article but do not reveal the main conclusions.
  • Interrogative titles introduce the subject in the form of a question. [6] X Research source

Step 6 Avoid titles that are too long.

  • Look for attention-grabbing descriptions or phrases you're proud of. For example, in an essay on censorship choose a phrase like "forbidden music" that is descriptive but also intriguing.

Step 8 Review your sources.

  • For example, in an essay on religious persecution, a quote like "God was silent" is arresting and thought-provoking. Readers may immediately agree or disagree and will want to read your explanation.
  • If you use someone else's words, make sure to put them in quotation marks, even in the title.

Step 9 Create a list of possible titles.

  • The Negative Impact of Replacement Referees on Football Fans (Theme and Audience)
  • "A Crucible of Victory": Understanding the Western Front in World War One (Quote and Theme)
  • The Queen of Diamonds: Marie-Antoinette and Revolutionary Propaganda (Phrase and Theme)

Step 10 Respect conventions.

  • Most words in your title should begin with a capital letter.
  • The first word and the first word after a colon should always be capitalized even if one of the "short words."
  • In general, do not capitalize the following words: and, a, an, the, or short prepositions if they are not the first letter in the title.
  • If the title of a book or film is part of your essay title, it should be put in italics, e.g., Gender Relationships Between Vampires in Twilight. Short story titles are always in quotation marks.
  • Know if the paper follows MLA, APA, or another style. Websites like Purdue University's Online Writing Lab , APA Style , and MLA Handbook can help you with conventions for titles.

Writing a Title for Fiction

Step 1 Brainstorm ideas.

  • For example, many young adult fantasy novels hinge on one or two intriguing words: Twilight, Bitten, Cinder, The Selection .

Step 3 Make the title exciting.

  • Try adding a more descriptive word to the basic title. Successful titles using the above words include The Giving Tree, A Tree Grows In Brooklyn, The Mystery of the Blue Train , and The Orphan Train .

Step 4 Make the title easy to remember.

  • Read your title out loud. Does it roll off the tongue? Is it exciting? Does it sound boring? Would you check out this title? The answers to these questions can help you revise the title.

Step 5 Pay attention to the wording.

  • For example, the use of the word desire in Eugene O'Neill's Desire Under the Elms is far more interesting than Love Under the Elms . [10] X Research source

Step 7 Seek inspiration.

  • Examples of this type of title include: The Grapes of Wrath; Absalom, Absalom; Gaudy Night and, The Fault in Our Stars .

Step 8 Read your own work.

  • Examples of this type of title include To Kill a Mockingbird, Catch-22, and Catcher in the Rye.

Step 9 Write down your inspirations when they come.

Draw inspiration for a variety of sources. "Ideas seem to come from everywhere – my life, everything I see, hear, and read, and most of all, from my imagination. I have a lot of imagination."

Community Q&A

Tom De Backer

  • Write the whole essay, go to your thesis and find a way to narrow it down to two to four words. Thanks Helpful 3 Not Helpful 0
  • Try this template to generate a good title. Thanks Helpful 4 Not Helpful 2

how to come up with a good title for research paper

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Write in Third Person

  • ↑ https://www.trentu.ca/academicskills/how-guides/how-write-university/how-approach-any-assignment/writing-english-essay/drafting-english
  • ↑ https://www.grammarly.com/blog/themes/
  • ↑ https://owl.purdue.edu/owl/general_writing/common_writing_assignments/research_papers/identifying_audiences.html
  • ↑ https://writing.umn.edu/sws/assets/pdf/quicktips/titles.pdf
  • ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398294/
  • ↑ https://blog.efpsa.org/2012/09/01/how-to-write-a-good-title-for-journal-articles/
  • ↑ https://library.sacredheart.edu/c.php?g=29803&p=185911
  • ↑ https://libguides.usc.edu/writingguide/title
  • ↑ https://writingcenter.unc.edu/tips-and-tools/brainstorming/
  • ↑ https://www.writersdigest.com/at-work-on-first-draft/7-tips-to-nail-the-perfect-title

About This Article

Rachel Scoggins, PhD

To help you come up with a title for an essay, write a draft of your paper first so you know what its main themes are. Then, write down key points in your essay that you could include in the title. Before making a decision, take your audience into account, such as by trying to include keywords in a title if your article is for an online audience. Additionally, decide whether you want to state the conclusion of your piece up front with a declarative title or introduce the subject as a question with an interrogative title. For tips on how to come up with a title for a story or other work of fiction, read on! Did this summary help you? Yes No

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Cultural Relativity and Acceptance of Embryonic Stem Cell Research

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Main Article Content

There is a debate about the ethical implications of using human embryos in stem cell research, which can be influenced by cultural, moral, and social values. This paper argues for an adaptable framework to accommodate diverse cultural and religious perspectives. By using an adaptive ethics model, research protections can reflect various populations and foster growth in stem cell research possibilities.

INTRODUCTION

Stem cell research combines biology, medicine, and technology, promising to alter health care and the understanding of human development. Yet, ethical contention exists because of individuals’ perceptions of using human embryos based on their various cultural, moral, and social values. While these disagreements concerning policy, use, and general acceptance have prompted the development of an international ethics policy, such a uniform approach can overlook the nuanced ethical landscapes between cultures. With diverse viewpoints in public health, a single global policy, especially one reflecting Western ethics or the ethics prevalent in high-income countries, is impractical. This paper argues for a culturally sensitive, adaptable framework for the use of embryonic stem cells. Stem cell policy should accommodate varying ethical viewpoints and promote an effective global dialogue. With an extension of an ethics model that can adapt to various cultures, we recommend localized guidelines that reflect the moral views of the people those guidelines serve.

Stem cells, characterized by their unique ability to differentiate into various cell types, enable the repair or replacement of damaged tissues. Two primary types of stem cells are somatic stem cells (adult stem cells) and embryonic stem cells. Adult stem cells exist in developed tissues and maintain the body’s repair processes. [1] Embryonic stem cells (ESC) are remarkably pluripotent or versatile, making them valuable in research. [2] However, the use of ESCs has sparked ethics debates. Considering the potential of embryonic stem cells, research guidelines are essential. The International Society for Stem Cell Research (ISSCR) provides international stem cell research guidelines. They call for “public conversations touching on the scientific significance as well as the societal and ethical issues raised by ESC research.” [3] The ISSCR also publishes updates about culturing human embryos 14 days post fertilization, suggesting local policies and regulations should continue to evolve as ESC research develops. [4]  Like the ISSCR, which calls for local law and policy to adapt to developing stem cell research given cultural acceptance, this paper highlights the importance of local social factors such as religion and culture.

I.     Global Cultural Perspective of Embryonic Stem Cells

Views on ESCs vary throughout the world. Some countries readily embrace stem cell research and therapies, while others have stricter regulations due to ethical concerns surrounding embryonic stem cells and when an embryo becomes entitled to moral consideration. The philosophical issue of when the “someone” begins to be a human after fertilization, in the morally relevant sense, [5] impacts when an embryo becomes not just worthy of protection but morally entitled to it. The process of creating embryonic stem cell lines involves the destruction of the embryos for research. [6] Consequently, global engagement in ESC research depends on social-cultural acceptability.

a.     US and Rights-Based Cultures

In the United States, attitudes toward stem cell therapies are diverse. The ethics and social approaches, which value individualism, [7] trigger debates regarding the destruction of human embryos, creating a complex regulatory environment. For example, the 1996 Dickey-Wicker Amendment prohibited federal funding for the creation of embryos for research and the destruction of embryos for “more than allowed for research on fetuses in utero.” [8] Following suit, in 2001, the Bush Administration heavily restricted stem cell lines for research. However, the Stem Cell Research Enhancement Act of 2005 was proposed to help develop ESC research but was ultimately vetoed. [9] Under the Obama administration, in 2009, an executive order lifted restrictions allowing for more development in this field. [10] The flux of research capacity and funding parallels the different cultural perceptions of human dignity of the embryo and how it is socially presented within the country’s research culture. [11]

b.     Ubuntu and Collective Cultures

African bioethics differs from Western individualism because of the different traditions and values. African traditions, as described by individuals from South Africa and supported by some studies in other African countries, including Ghana and Kenya, follow the African moral philosophies of Ubuntu or Botho and Ukama , which “advocates for a form of wholeness that comes through one’s relationship and connectedness with other people in the society,” [12] making autonomy a socially collective concept. In this context, for the community to act autonomously, individuals would come together to decide what is best for the collective. Thus, stem cell research would require examining the value of the research to society as a whole and the use of the embryos as a collective societal resource. If society views the source as part of the collective whole, and opposes using stem cells, compromising the cultural values to pursue research may cause social detachment and stunt research growth. [13] Based on local culture and moral philosophy, the permissibility of stem cell research depends on how embryo, stem cell, and cell line therapies relate to the community as a whole. Ubuntu is the expression of humanness, with the person’s identity drawn from the “’I am because we are’” value. [14] The decision in a collectivistic culture becomes one born of cultural context, and individual decisions give deference to others in the society.

Consent differs in cultures where thought and moral philosophy are based on a collective paradigm. So, applying Western bioethical concepts is unrealistic. For one, Africa is a diverse continent with many countries with different belief systems, access to health care, and reliance on traditional or Western medicines. Where traditional medicine is the primary treatment, the “’restrictive focus on biomedically-related bioethics’” [is] problematic in African contexts because it neglects bioethical issues raised by traditional systems.” [15] No single approach applies in all areas or contexts. Rather than evaluating the permissibility of ESC research according to Western concepts such as the four principles approach, different ethics approaches should prevail.

Another consideration is the socio-economic standing of countries. In parts of South Africa, researchers have not focused heavily on contributing to the stem cell discourse, either because it is not considered health care or a health science priority or because resources are unavailable. [16] Each country’s priorities differ given different social, political, and economic factors. In South Africa, for instance, areas such as maternal mortality, non-communicable diseases, telemedicine, and the strength of health systems need improvement and require more focus. [17] Stem cell research could benefit the population, but it also could divert resources from basic medical care. Researchers in South Africa adhere to the National Health Act and Medicines Control Act in South Africa and international guidelines; however, the Act is not strictly enforced, and there is no clear legislation for research conduct or ethical guidelines. [18]

Some parts of Africa condemn stem cell research. For example, 98.2 percent of the Tunisian population is Muslim. [19] Tunisia does not permit stem cell research because of moral conflict with a Fatwa. Religion heavily saturates the regulation and direction of research. [20] Stem cell use became permissible for reproductive purposes only recently, with tight restrictions preventing cells from being used in any research other than procedures concerning ART/IVF.  Their use is conditioned on consent, and available only to married couples. [21] The community's receptiveness to stem cell research depends on including communitarian African ethics.

c.     Asia

Some Asian countries also have a collective model of ethics and decision making. [22] In China, the ethics model promotes a sincere respect for life or human dignity, [23] based on protective medicine. This model, influenced by Traditional Chinese Medicine (TCM), [24] recognizes Qi as the vital energy delivered via the meridians of the body; it connects illness to body systems, the body’s entire constitution, and the universe for a holistic bond of nature, health, and quality of life. [25] Following a protective ethics model, and traditional customs of wholeness, investment in stem cell research is heavily desired for its applications in regenerative therapies, disease modeling, and protective medicines. In a survey of medical students and healthcare practitioners, 30.8 percent considered stem cell research morally unacceptable while 63.5 percent accepted medical research using human embryonic stem cells. Of these individuals, 89.9 percent supported increased funding for stem cell research. [26] The scientific community might not reflect the overall population. From 1997 to 2019, China spent a total of $576 million (USD) on stem cell research at 8,050 stem cell programs, increased published presence from 0.6 percent to 14.01 percent of total global stem cell publications as of 2014, and made significant strides in cell-based therapies for various medical conditions. [27] However, while China has made substantial investments in stem cell research and achieved notable progress in clinical applications, concerns linger regarding ethical oversight and transparency. [28] For example, the China Biosecurity Law, promoted by the National Health Commission and China Hospital Association, attempted to mitigate risks by introducing an institutional review board (IRB) in the regulatory bodies. 5800 IRBs registered with the Chinese Clinical Trial Registry since 2021. [29] However, issues still need to be addressed in implementing effective IRB review and approval procedures.

The substantial government funding and focus on scientific advancement have sometimes overshadowed considerations of regional cultures, ethnic minorities, and individual perspectives, particularly evident during the one-child policy era. As government policy adapts to promote public stability, such as the change from the one-child to the two-child policy, [30] research ethics should also adapt to ensure respect for the values of its represented peoples.

Japan is also relatively supportive of stem cell research and therapies. Japan has a more transparent regulatory framework, allowing for faster approval of regenerative medicine products, which has led to several advanced clinical trials and therapies. [31] South Korea is also actively engaged in stem cell research and has a history of breakthroughs in cloning and embryonic stem cells. [32] However, the field is controversial, and there are issues of scientific integrity. For example, the Korean FDA fast-tracked products for approval, [33] and in another instance, the oocyte source was unclear and possibly violated ethical standards. [34] Trust is important in research, as it builds collaborative foundations between colleagues, trial participant comfort, open-mindedness for complicated and sensitive discussions, and supports regulatory procedures for stakeholders. There is a need to respect the culture’s interest, engagement, and for research and clinical trials to be transparent and have ethical oversight to promote global research discourse and trust.

d.     Middle East

Countries in the Middle East have varying degrees of acceptance of or restrictions to policies related to using embryonic stem cells due to cultural and religious influences. Saudi Arabia has made significant contributions to stem cell research, and conducts research based on international guidelines for ethical conduct and under strict adherence to guidelines in accordance with Islamic principles. Specifically, the Saudi government and people require ESC research to adhere to Sharia law. In addition to umbilical and placental stem cells, [35] Saudi Arabia permits the use of embryonic stem cells as long as they come from miscarriages, therapeutic abortions permissible by Sharia law, or are left over from in vitro fertilization and donated to research. [36] Laws and ethical guidelines for stem cell research allow the development of research institutions such as the King Abdullah International Medical Research Center, which has a cord blood bank and a stem cell registry with nearly 10,000 donors. [37] Such volume and acceptance are due to the ethical ‘permissibility’ of the donor sources, which do not conflict with religious pillars. However, some researchers err on the side of caution, choosing not to use embryos or fetal tissue as they feel it is unethical to do so. [38]

Jordan has a positive research ethics culture. [39] However, there is a significant issue of lack of trust in researchers, with 45.23 percent (38.66 percent agreeing and 6.57 percent strongly agreeing) of Jordanians holding a low level of trust in researchers, compared to 81.34 percent of Jordanians agreeing that they feel safe to participate in a research trial. [40] Safety testifies to the feeling of confidence that adequate measures are in place to protect participants from harm, whereas trust in researchers could represent the confidence in researchers to act in the participants’ best interests, adhere to ethical guidelines, provide accurate information, and respect participants’ rights and dignity. One method to improve trust would be to address communication issues relevant to ESC. Legislation surrounding stem cell research has adopted specific language, especially concerning clarification “between ‘stem cells’ and ‘embryonic stem cells’” in translation. [41] Furthermore, legislation “mandates the creation of a national committee… laying out specific regulations for stem-cell banking in accordance with international standards.” [42] This broad regulation opens the door for future global engagement and maintains transparency. However, these regulations may also constrain the influence of research direction, pace, and accessibility of research outcomes.

e.     Europe

In the European Union (EU), ethics is also principle-based, but the principles of autonomy, dignity, integrity, and vulnerability are interconnected. [43] As such, the opportunity for cohesion and concessions between individuals’ thoughts and ideals allows for a more adaptable ethics model due to the flexible principles that relate to the human experience The EU has put forth a framework in its Convention for the Protection of Human Rights and Dignity of the Human Being allowing member states to take different approaches. Each European state applies these principles to its specific conventions, leading to or reflecting different acceptance levels of stem cell research. [44]

For example, in Germany, Lebenzusammenhang , or the coherence of life, references integrity in the unity of human culture. Namely, the personal sphere “should not be subject to external intervention.” [45]  Stem cell interventions could affect this concept of bodily completeness, leading to heavy restrictions. Under the Grundgesetz, human dignity and the right to life with physical integrity are paramount. [46] The Embryo Protection Act of 1991 made producing cell lines illegal. Cell lines can be imported if approved by the Central Ethics Commission for Stem Cell Research only if they were derived before May 2007. [47] Stem cell research respects the integrity of life for the embryo with heavy specifications and intense oversight. This is vastly different in Finland, where the regulatory bodies find research more permissible in IVF excess, but only up to 14 days after fertilization. [48] Spain’s approach differs still, with a comprehensive regulatory framework. [49] Thus, research regulation can be culture-specific due to variations in applied principles. Diverse cultures call for various approaches to ethical permissibility. [50] Only an adaptive-deliberative model can address the cultural constructions of self and achieve positive, culturally sensitive stem cell research practices. [51]

II.     Religious Perspectives on ESC

Embryonic stem cell sources are the main consideration within religious contexts. While individuals may not regard their own religious texts as authoritative or factual, religion can shape their foundations or perspectives.

The Qur'an states:

“And indeed We created man from a quintessence of clay. Then We placed within him a small quantity of nutfa (sperm to fertilize) in a safe place. Then We have fashioned the nutfa into an ‘alaqa (clinging clot or cell cluster), then We developed the ‘alaqa into mudgha (a lump of flesh), and We made mudgha into bones, and clothed the bones with flesh, then We brought it into being as a new creation. So Blessed is Allah, the Best of Creators.” [52]

Many scholars of Islam estimate the time of soul installment, marked by the angel breathing in the soul to bring the individual into creation, as 120 days from conception. [53] Personhood begins at this point, and the value of life would prohibit research or experimentation that could harm the individual. If the fetus is more than 120 days old, the time ensoulment is interpreted to occur according to Islamic law, abortion is no longer permissible. [54] There are a few opposing opinions about early embryos in Islamic traditions. According to some Islamic theologians, there is no ensoulment of the early embryo, which is the source of stem cells for ESC research. [55]

In Buddhism, the stance on stem cell research is not settled. The main tenets, the prohibition against harming or destroying others (ahimsa) and the pursuit of knowledge (prajña) and compassion (karuna), leave Buddhist scholars and communities divided. [56] Some scholars argue stem cell research is in accordance with the Buddhist tenet of seeking knowledge and ending human suffering. Others feel it violates the principle of not harming others. Finding the balance between these two points relies on the karmic burden of Buddhist morality. In trying to prevent ahimsa towards the embryo, Buddhist scholars suggest that to comply with Buddhist tenets, research cannot be done as the embryo has personhood at the moment of conception and would reincarnate immediately, harming the individual's ability to build their karmic burden. [57] On the other hand, the Bodhisattvas, those considered to be on the path to enlightenment or Nirvana, have given organs and flesh to others to help alleviate grieving and to benefit all. [58] Acceptance varies on applied beliefs and interpretations.

Catholicism does not support embryonic stem cell research, as it entails creation or destruction of human embryos. This destruction conflicts with the belief in the sanctity of life. For example, in the Old Testament, Genesis describes humanity as being created in God’s image and multiplying on the Earth, referencing the sacred rights to human conception and the purpose of development and life. In the Ten Commandments, the tenet that one should not kill has numerous interpretations where killing could mean murder or shedding of the sanctity of life, demonstrating the high value of human personhood. In other books, the theological conception of when life begins is interpreted as in utero, [59] highlighting the inviolability of life and its formation in vivo to make a religious point for accepting such research as relatively limited, if at all. [60] The Vatican has released ethical directives to help apply a theological basis to modern-day conflicts. The Magisterium of the Church states that “unless there is a moral certainty of not causing harm,” experimentation on fetuses, fertilized cells, stem cells, or embryos constitutes a crime. [61] Such procedures would not respect the human person who exists at these stages, according to Catholicism. Damages to the embryo are considered gravely immoral and illicit. [62] Although the Catholic Church officially opposes abortion, surveys demonstrate that many Catholic people hold pro-choice views, whether due to the context of conception, stage of pregnancy, threat to the mother’s life, or for other reasons, demonstrating that practicing members can also accept some but not all tenets. [63]

Some major Jewish denominations, such as the Reform, Conservative, and Reconstructionist movements, are open to supporting ESC use or research as long as it is for saving a life. [64] Within Judaism, the Talmud, or study, gives personhood to the child at birth and emphasizes that life does not begin at conception: [65]

“If she is found pregnant, until the fortieth day it is mere fluid,” [66]

Whereas most religions prioritize the status of human embryos, the Halakah (Jewish religious law) states that to save one life, most other religious laws can be ignored because it is in pursuit of preservation. [67] Stem cell research is accepted due to application of these religious laws.

We recognize that all religions contain subsets and sects. The variety of environmental and cultural differences within religious groups requires further analysis to respect the flexibility of religious thoughts and practices. We make no presumptions that all cultures require notions of autonomy or morality as under the common morality theory , which asserts a set of universal moral norms that all individuals share provides moral reasoning and guides ethical decisions. [68] We only wish to show that the interaction with morality varies between cultures and countries.

III.     A Flexible Ethical Approach

The plurality of different moral approaches described above demonstrates that there can be no universally acceptable uniform law for ESC on a global scale. Instead of developing one standard, flexible ethical applications must be continued. We recommend local guidelines that incorporate important cultural and ethical priorities.

While the Declaration of Helsinki is more relevant to people in clinical trials receiving ESC products, in keeping with the tradition of protections for research subjects, consent of the donor is an ethical requirement for ESC donation in many jurisdictions including the US, Canada, and Europe. [69] The Declaration of Helsinki provides a reference point for regulatory standards and could potentially be used as a universal baseline for obtaining consent prior to gamete or embryo donation.

For instance, in Columbia University’s egg donor program for stem cell research, donors followed standard screening protocols and “underwent counseling sessions that included information as to the purpose of oocyte donation for research, what the oocytes would be used for, the risks and benefits of donation, and process of oocyte stimulation” to ensure transparency for consent. [70] The program helped advance stem cell research and provided clear and safe research methods with paid participants. Though paid participation or covering costs of incidental expenses may not be socially acceptable in every culture or context, [71] and creating embryos for ESC research is illegal in many jurisdictions, Columbia’s program was effective because of the clear and honest communications with donors, IRBs, and related stakeholders.  This example demonstrates that cultural acceptance of scientific research and of the idea that an egg or embryo does not have personhood is likely behind societal acceptance of donating eggs for ESC research. As noted, many countries do not permit the creation of embryos for research.

Proper communication and education regarding the process and purpose of stem cell research may bolster comprehension and garner more acceptance. “Given the sensitive subject material, a complete consent process can support voluntary participation through trust, understanding, and ethical norms from the cultures and morals participants value. This can be hard for researchers entering countries of different socioeconomic stability, with different languages and different societal values. [72]

An adequate moral foundation in medical ethics is derived from the cultural and religious basis that informs knowledge and actions. [73] Understanding local cultural and religious values and their impact on research could help researchers develop humility and promote inclusion.

IV.     Concerns

Some may argue that if researchers all adhere to one ethics standard, protection will be satisfied across all borders, and the global public will trust researchers. However, defining what needs to be protected and how to define such research standards is very specific to the people to which standards are applied. We suggest that applying one uniform guide cannot accurately protect each individual because we all possess our own perceptions and interpretations of social values. [74] Therefore, the issue of not adjusting to the moral pluralism between peoples in applying one standard of ethics can be resolved by building out ethics models that can be adapted to different cultures and religions.

Other concerns include medical tourism, which may promote health inequities. [75] Some countries may develop and approve products derived from ESC research before others, compromising research ethics or drug approval processes. There are also concerns about the sale of unauthorized stem cell treatments, for example, those without FDA approval in the United States. Countries with robust research infrastructures may be tempted to attract medical tourists, and some customers will have false hopes based on aggressive publicity of unproven treatments. [76]

For example, in China, stem cell clinics can market to foreign clients who are not protected under the regulatory regimes. Companies employ a marketing strategy of “ethically friendly” therapies. Specifically, in the case of Beike, China’s leading stem cell tourism company and sprouting network, ethical oversight of administrators or health bureaus at one site has “the unintended consequence of shifting questionable activities to another node in Beike's diffuse network.” [77] In contrast, Jordan is aware of stem cell research’s potential abuse and its own status as a “health-care hub.” Jordan’s expanded regulations include preserving the interests of individuals in clinical trials and banning private companies from ESC research to preserve transparency and the integrity of research practices. [78]

The social priorities of the community are also a concern. The ISSCR explicitly states that guidelines “should be periodically revised to accommodate scientific advances, new challenges, and evolving social priorities.” [79] The adaptable ethics model extends this consideration further by addressing whether research is warranted given the varying degrees of socioeconomic conditions, political stability, and healthcare accessibilities and limitations. An ethical approach would require discussion about resource allocation and appropriate distribution of funds. [80]

While some religions emphasize the sanctity of life from conception, which may lead to public opposition to ESC research, others encourage ESC research due to its potential for healing and alleviating human pain. Many countries have special regulations that balance local views on embryonic personhood, the benefits of research as individual or societal goods, and the protection of human research subjects. To foster understanding and constructive dialogue, global policy frameworks should prioritize the protection of universal human rights, transparency, and informed consent. In addition to these foundational global policies, we recommend tailoring local guidelines to reflect the diverse cultural and religious perspectives of the populations they govern. Ethics models should be adapted to local populations to effectively establish research protections, growth, and possibilities of stem cell research.

For example, in countries with strong beliefs in the moral sanctity of embryos or heavy religious restrictions, an adaptive model can allow for discussion instead of immediate rejection. In countries with limited individual rights and voice in science policy, an adaptive model ensures cultural, moral, and religious views are taken into consideration, thereby building social inclusion. While this ethical consideration by the government may not give a complete voice to every individual, it will help balance policies and maintain the diverse perspectives of those it affects. Embracing an adaptive ethics model of ESC research promotes open-minded dialogue and respect for the importance of human belief and tradition. By actively engaging with cultural and religious values, researchers can better handle disagreements and promote ethical research practices that benefit each society.

This brief exploration of the religious and cultural differences that impact ESC research reveals the nuances of relative ethics and highlights a need for local policymakers to apply a more intense adaptive model.

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[25] Li, X.-T., & Zhao, J. (2012). Chapter 4: An Approach to the Nature of Qi in TCM- Qi and Bioenergy. In Recent Advances in Theories and Practice of Chinese Medicine (p. 79). InTech.

[26] Luo, D., Xu, Z., Wang, Z., & Ran, W. (2021). China's Stem Cell Research and Knowledge Levels of Medical Practitioners and Students.  Stem cells international ,  2021 , 6667743. https://doi.org/10.1155/2021/6667743

[27] Luo, D., Xu, Z., Wang, Z., & Ran, W. (2021). China's Stem Cell Research and Knowledge Levels of Medical Practitioners and Students.  Stem cells international ,  2021 , 6667743. https://doi.org/10.1155/2021/6667743

[28] Zhang, J. Y. (2017). Lost in translation? accountability and governance of Clinical Stem Cell Research in China. Regenerative Medicine , 12 (6), 647–656. https://doi.org/10.2217/rme-2017-0035

[29] Wang, L., Wang, F., & Zhang, W. (2021). Bioethics in China’s biosecurity law: Forms, effects, and unsettled issues. Journal of law and the biosciences , 8(1).  https://doi.org/10.1093/jlb/lsab019 https://academic.oup.com/jlb/article/8/1/lsab019/6299199

[30] Chen, H., Wei, T., Wang, H.  et al.  Association of China’s two-child policy with changes in number of births and birth defects rate, 2008–2017.  BMC Public Health   22 , 434 (2022). https://doi.org/10.1186/s12889-022-12839-0

[31] Azuma, K. Regulatory Landscape of Regenerative Medicine in Japan.  Curr Stem Cell Rep   1 , 118–128 (2015). https://doi.org/10.1007/s40778-015-0012-6

[32] Harris, R. (2005, May 19). Researchers Report Advance in Stem Cell Production . NPR. https://www.npr.org/2005/05/19/4658967/researchers-report-advance-in-stem-cell-production

[33] Park, S. (2012). South Korea steps up stem-cell work.  Nature . https://doi.org/10.1038/nature.2012.10565

[34] Resnik, D. B., Shamoo, A. E., & Krimsky, S. (2006). Fraudulent human embryonic stem cell research in South Korea: lessons learned.  Accountability in research ,  13 (1), 101–109. https://doi.org/10.1080/08989620600634193 .

[35] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: interviews with researchers from Saudi Arabia. BMC medical ethics, 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6

[36] Association for the Advancement of Blood and Biotherapies.  https://www.aabb.org/regulatory-and-advocacy/regulatory-affairs/regulatory-for-cellular-therapies/international-competent-authorities/saudi-arabia

[37] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: Interviews with researchers from Saudi Arabia.  BMC medical ethics ,  21 (1), 35. https://doi.org/10.1186/s12910-020-00482-6

[38] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: Interviews with researchers from Saudi Arabia. BMC medical ethics , 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6

Culturally, autonomy practices follow a relational autonomy approach based on a paternalistic deontological health care model. The adherence to strict international research policies and religious pillars within the regulatory environment is a great foundation for research ethics. However, there is a need to develop locally targeted ethics approaches for research (as called for in Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: interviews with researchers from Saudi Arabia. BMC medical ethics, 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6), this decision-making approach may help advise a research decision model. For more on the clinical cultural autonomy approaches, see: Alabdullah, Y. Y., Alzaid, E., Alsaad, S., Alamri, T., Alolayan, S. W., Bah, S., & Aljoudi, A. S. (2022). Autonomy and paternalism in Shared decision‐making in a Saudi Arabian tertiary hospital: A cross‐sectional study. Developing World Bioethics , 23 (3), 260–268. https://doi.org/10.1111/dewb.12355 ; Bukhari, A. A. (2017). Universal Principles of Bioethics and Patient Rights in Saudi Arabia (Doctoral dissertation, Duquesne University). https://dsc.duq.edu/etd/124; Ladha, S., Nakshawani, S. A., Alzaidy, A., & Tarab, B. (2023, October 26). Islam and Bioethics: What We All Need to Know . Columbia University School of Professional Studies. https://sps.columbia.edu/events/islam-and-bioethics-what-we-all-need-know

[39] Ababneh, M. A., Al-Azzam, S. I., Alzoubi, K., Rababa’h, A., & Al Demour, S. (2021). Understanding and attitudes of the Jordanian public about clinical research ethics.  Research Ethics ,  17 (2), 228-241.  https://doi.org/10.1177/1747016120966779

[40] Ababneh, M. A., Al-Azzam, S. I., Alzoubi, K., Rababa’h, A., & Al Demour, S. (2021). Understanding and attitudes of the Jordanian public about clinical research ethics.  Research Ethics ,  17 (2), 228-241.  https://doi.org/10.1177/1747016120966779

[41] Dajani, R. (2014). Jordan’s stem-cell law can guide the Middle East.  Nature  510, 189. https://doi.org/10.1038/510189a

[42] Dajani, R. (2014). Jordan’s stem-cell law can guide the Middle East.  Nature  510, 189. https://doi.org/10.1038/510189a

[43] The EU’s definition of autonomy relates to the capacity for creating ideas, moral insight, decisions, and actions without constraint, personal responsibility, and informed consent. However, the EU views autonomy as not completely able to protect individuals and depends on other principles, such as dignity, which “expresses the intrinsic worth and fundamental equality of all human beings.” Rendtorff, J.D., Kemp, P. (2019). Four Ethical Principles in European Bioethics and Biolaw: Autonomy, Dignity, Integrity and Vulnerability. In: Valdés, E., Lecaros, J. (eds) Biolaw and Policy in the Twenty-First Century. International Library of Ethics, Law, and the New Medicine, vol 78. Springer, Cham. https://doi.org/10.1007/978-3-030-05903-3_3

[44] Council of Europe. Convention for the protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine: Convention on Human Rights and Biomedicine (ETS No. 164) https://www.coe.int/en/web/conventions/full-list?module=treaty-detail&treatynum=164 (forbidding the creation of embryos for research purposes only, and suggests embryos in vitro have protections.); Also see Drabiak-Syed B. K. (2013). New President, New Human Embryonic Stem Cell Research Policy: Comparative International Perspectives and Embryonic Stem Cell Research Laws in France.  Biotechnology Law Report ,  32 (6), 349–356. https://doi.org/10.1089/blr.2013.9865

[45] Rendtorff, J.D., Kemp, P. (2019). Four Ethical Principles in European Bioethics and Biolaw: Autonomy, Dignity, Integrity and Vulnerability. In: Valdés, E., Lecaros, J. (eds) Biolaw and Policy in the Twenty-First Century. International Library of Ethics, Law, and the New Medicine, vol 78. Springer, Cham. https://doi.org/10.1007/978-3-030-05903-3_3

[46] Tomuschat, C., Currie, D. P., Kommers, D. P., & Kerr, R. (Trans.). (1949, May 23). Basic law for the Federal Republic of Germany. https://www.btg-bestellservice.de/pdf/80201000.pdf

[47] Regulation of Stem Cell Research in Germany . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-germany

[48] Regulation of Stem Cell Research in Finland . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-finland

[49] Regulation of Stem Cell Research in Spain . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-spain

[50] Some sources to consider regarding ethics models or regulatory oversights of other cultures not covered:

Kara MA. Applicability of the principle of respect for autonomy: the perspective of Turkey. J Med Ethics. 2007 Nov;33(11):627-30. doi: 10.1136/jme.2006.017400. PMID: 17971462; PMCID: PMC2598110.

Ugarte, O. N., & Acioly, M. A. (2014). The principle of autonomy in Brazil: one needs to discuss it ...  Revista do Colegio Brasileiro de Cirurgioes ,  41 (5), 374–377. https://doi.org/10.1590/0100-69912014005013

Bharadwaj, A., & Glasner, P. E. (2012). Local cells, global science: The rise of embryonic stem cell research in India . Routledge.

For further research on specific European countries regarding ethical and regulatory framework, we recommend this database: Regulation of Stem Cell Research in Europe . Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-europe   

[51] Klitzman, R. (2006). Complications of culture in obtaining informed consent. The American Journal of Bioethics, 6(1), 20–21. https://doi.org/10.1080/15265160500394671 see also: Ekmekci, P. E., & Arda, B. (2017). Interculturalism and Informed Consent: Respecting Cultural Differences without Breaching Human Rights.  Cultura (Iasi, Romania) ,  14 (2), 159–172.; For why trust is important in research, see also: Gray, B., Hilder, J., Macdonald, L., Tester, R., Dowell, A., & Stubbe, M. (2017). Are research ethics guidelines culturally competent?  Research Ethics ,  13 (1), 23-41.  https://doi.org/10.1177/1747016116650235

[52] The Qur'an  (M. Khattab, Trans.). (1965). Al-Mu’minun, 23: 12-14. https://quran.com/23

[53] Lenfest, Y. (2017, December 8). Islam and the beginning of human life . Bill of Health. https://blog.petrieflom.law.harvard.edu/2017/12/08/islam-and-the-beginning-of-human-life/

[54] Aksoy, S. (2005). Making regulations and drawing up legislation in Islamic countries under conditions of uncertainty, with special reference to embryonic stem cell research. Journal of Medical Ethics , 31: 399-403.; see also: Mahmoud, Azza. "Islamic Bioethics: National Regulations and Guidelines of Human Stem Cell Research in the Muslim World." Master's thesis, Chapman University, 2022. https://doi.org/10.36837/ chapman.000386

[55] Rashid, R. (2022). When does Ensoulment occur in the Human Foetus. Journal of the British Islamic Medical Association , 12 (4). ISSN 2634 8071. https://www.jbima.com/wp-content/uploads/2023/01/2-Ethics-3_-Ensoulment_Rafaqat.pdf.

[56] Sivaraman, M. & Noor, S. (2017). Ethics of embryonic stem cell research according to Buddhist, Hindu, Catholic, and Islamic religions: perspective from Malaysia. Asian Biomedicine,8(1) 43-52.  https://doi.org/10.5372/1905-7415.0801.260

[57] Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.),  Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues  (pp. 79-94). Berkeley: University of California Press.  https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005

[58] Lecso, P. A. (1991). The Bodhisattva Ideal and Organ Transplantation.  Journal of Religion and Health ,  30 (1), 35–41. http://www.jstor.org/stable/27510629 ; Bodhisattva, S. (n.d.). The Key of Becoming a Bodhisattva . A Guide to the Bodhisattva Way of Life. http://www.buddhism.org/Sutras/2/BodhisattvaWay.htm

[59] There is no explicit religious reference to when life begins or how to conduct research that interacts with the concept of life. However, these are relevant verses pertaining to how the fetus is viewed. (( King James Bible . (1999). Oxford University Press. (original work published 1769))

Jerimiah 1: 5 “Before I formed thee in the belly I knew thee; and before thou camest forth out of the womb I sanctified thee…”

In prophet Jerimiah’s insight, God set him apart as a person known before childbirth, a theme carried within the Psalm of David.

Psalm 139: 13-14 “…Thou hast covered me in my mother's womb. I will praise thee; for I am fearfully and wonderfully made…”

These verses demonstrate David’s respect for God as an entity that would know of all man’s thoughts and doings even before birth.

[60] It should be noted that abortion is not supported as well.

[61] The Vatican. (1987, February 22). Instruction on Respect for Human Life in Its Origin and on the Dignity of Procreation Replies to Certain Questions of the Day . Congregation For the Doctrine of the Faith. https://www.vatican.va/roman_curia/congregations/cfaith/documents/rc_con_cfaith_doc_19870222_respect-for-human-life_en.html

[62] The Vatican. (2000, August 25). Declaration On the Production and the Scientific and Therapeutic Use of Human Embryonic Stem Cells . Pontifical Academy for Life. https://www.vatican.va/roman_curia/pontifical_academies/acdlife/documents/rc_pa_acdlife_doc_20000824_cellule-staminali_en.html ; Ohara, N. (2003). Ethical Consideration of Experimentation Using Living Human Embryos: The Catholic Church’s Position on Human Embryonic Stem Cell Research and Human Cloning. Department of Obstetrics and Gynecology . Retrieved from https://article.imrpress.com/journal/CEOG/30/2-3/pii/2003018/77-81.pdf.

[63] Smith, G. A. (2022, May 23). Like Americans overall, Catholics vary in their abortion views, with regular mass attenders most opposed . Pew Research Center. https://www.pewresearch.org/short-reads/2022/05/23/like-americans-overall-catholics-vary-in-their-abortion-views-with-regular-mass-attenders-most-opposed/

[64] Rosner, F., & Reichman, E. (2002). Embryonic stem cell research in Jewish law. Journal of halacha and contemporary society , (43), 49–68.; Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.),  Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues  (pp. 79-94). Berkeley: University of California Press.  https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005

[65] Schenker J. G. (2008). The beginning of human life: status of embryo. Perspectives in Halakha (Jewish Religious Law).  Journal of assisted reproduction and genetics ,  25 (6), 271–276. https://doi.org/10.1007/s10815-008-9221-6

[66] Ruttenberg, D. (2020, May 5). The Torah of Abortion Justice (annotated source sheet) . Sefaria. https://www.sefaria.org/sheets/234926.7?lang=bi&with=all&lang2=en

[67] Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.),  Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues  (pp. 79-94). Berkeley: University of California Press.  https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005

[68] Gert, B. (2007). Common morality: Deciding what to do . Oxford Univ. Press.

[69] World Medical Association (2013). World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA , 310(20), 2191–2194. https://doi.org/10.1001/jama.2013.281053 Declaration of Helsinki – WMA – The World Medical Association .; see also: National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. (1979).  The Belmont report: Ethical principles and guidelines for the protection of human subjects of research . U.S. Department of Health and Human Services.  https://www.hhs.gov/ohrp/regulations-and-policy/belmont-report/read-the-belmont-report/index.html

[70] Zakarin Safier, L., Gumer, A., Kline, M., Egli, D., & Sauer, M. V. (2018). Compensating human subjects providing oocytes for stem cell research: 9-year experience and outcomes.  Journal of assisted reproduction and genetics ,  35 (7), 1219–1225. https://doi.org/10.1007/s10815-018-1171-z https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063839/ see also: Riordan, N. H., & Paz Rodríguez, J. (2021). Addressing concerns regarding associated costs, transparency, and integrity of research in recent stem cell trial. Stem Cells Translational Medicine , 10 (12), 1715–1716. https://doi.org/10.1002/sctm.21-0234

[71] Klitzman, R., & Sauer, M. V. (2009). Payment of egg donors in stem cell research in the USA.  Reproductive biomedicine online ,  18 (5), 603–608. https://doi.org/10.1016/s1472-6483(10)60002-8

[72] Krosin, M. T., Klitzman, R., Levin, B., Cheng, J., & Ranney, M. L. (2006). Problems in comprehension of informed consent in rural and peri-urban Mali, West Africa.  Clinical trials (London, England) ,  3 (3), 306–313. https://doi.org/10.1191/1740774506cn150oa

[73] Veatch, Robert M.  Hippocratic, Religious, and Secular Medical Ethics: The Points of Conflict . Georgetown University Press, 2012.

[74] Msoroka, M. S., & Amundsen, D. (2018). One size fits not quite all: Universal research ethics with diversity.  Research Ethics ,  14 (3), 1-17.  https://doi.org/10.1177/1747016117739939

[75] Pirzada, N. (2022). The Expansion of Turkey’s Medical Tourism Industry.  Voices in Bioethics ,  8 . https://doi.org/10.52214/vib.v8i.9894

[76] Stem Cell Tourism: False Hope for Real Money . Harvard Stem Cell Institute (HSCI). (2023). https://hsci.harvard.edu/stem-cell-tourism , See also: Bissassar, M. (2017). Transnational Stem Cell Tourism: An ethical analysis.  Voices in Bioethics ,  3 . https://doi.org/10.7916/vib.v3i.6027

[77] Song, P. (2011) The proliferation of stem cell therapies in post-Mao China: problematizing ethical regulation,  New Genetics and Society , 30:2, 141-153, DOI:  10.1080/14636778.2011.574375

[78] Dajani, R. (2014). Jordan’s stem-cell law can guide the Middle East.  Nature  510, 189. https://doi.org/10.1038/510189a

[79] International Society for Stem Cell Research. (2024). Standards in stem cell research . International Society for Stem Cell Research. https://www.isscr.org/guidelines/5-standards-in-stem-cell-research

[80] Benjamin, R. (2013). People’s science bodies and rights on the Stem Cell Frontier . Stanford University Press.

Mifrah Hayath

SM Candidate Harvard Medical School, MS Biotechnology Johns Hopkins University

Olivia Bowers

MS Bioethics Columbia University (Disclosure: affiliated with Voices in Bioethics)

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