how to write a manuscript for research paper

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A Brief Guide To Writing Your First Scientific Manuscript

I’ve had the privilege of writing a few manuscripts in my research career to date, and helping trainees write them. It’s hard work, but planning and organization helps. Here’s some thoughts on how to approach writing manuscripts based on original biomedical research.

Getting ready to write

Involve your principal investigator (PI) early and throughout the process. It’s our job to help you write!

Write down your hypothesis/research question. Everything else will be spun around this.

Gather your proposed figures and tables in a sequence that tells a story. This will form the basis of your Results section. Write bulleted captions for the figures/tables, including a title that explains the key finding for each figure/table, an explanation of experimental groups and associated symbols/labels, and details on biological and technical replicates and statements (such as “one of four representative experiments are shown.”)

Generate a bulleted outline of the major points for each section of the manuscript. This depends on the journal, but typically, and with minor variations: Introduction, Methods, Results, Discussion. Use Endnote, Reference Manager, Mendeley, or other citation software to start inserting references to go with bullets. Decide from the beginning what word processing software you’ll use (Word, Google Docs, etc.). Google Docs can be helpful for maintaining a single version of the manuscript, but citation software often doesn’t play well with Google Docs (whereas most software options can automatically update citation changes in Word). Here’s what should go in each of these sections:

Introduction: What did you study, and why is it important? What is your hypothesis/research question?

Methods: What techniques did you use? Each technique should be its own bullet, with sub-bullets for key details. If you used animal or human subjects, include a bullet on ethics approval. Important methodologies and materials, i.e., blinding for subjective analyses, full names of cell lines/strains/reagents and your commercial/academic sources for them.

Results: What were your findings? Each major finding should be its own bullet, with sub-bullets going into more detail for each major finding. These bullets should refer to your figures.

Discussion: Summarize your findings in the context of prior work. Discuss possible interpretations. It is important to include a bullet describing the limitations of the presented work. Mention possible future directions.

Now read the entire outline (including the figures). Is it a complete story? If so, you’re ready to prepare for submission. If not, you should have a good idea of what it will take to finish the manuscript.

Writing your manuscript

You first need to decide where you want to submit your manuscript. I like to consider my ideal target audience. I also like to vary which journals I publish in, both to broaden the potential readers of my papers and to avoid the appearance of having an unfair “inside connection” to a given journal. Your academic reputation is priceless.

Once you’ve chosen your journal, look at the journal’s article types. Decide which article type you would like to submit and reformat your outline according to the journal’s standards (including citation style).

Convert your outline (including the figure captions) to complete sentences. Don’t focus on writing perfect prose for the first draft. Write your abstract after the first draft is completed. Make sure the manuscript conforms to the target journal’s word and figure limits.

Discuss all possible authors with your PI. If the study involved many people, create a table of possible authors showing their specific contributions to the manuscript. (This is helpful to do in any case as many journals now require this information.) Assigning authorship is sometimes complicated, but keep in mind that the Acknowledgements can be used to recognize those who made minor contributions (including reading the manuscript to provide feedback). “Equal contribution” authorship positions for the first and last authors is a newer option for a number of journals. An alternative is to generate the initial outline or first draft with the help of co-authors. This can take a lot more work and coordination, but may make sense for highly collaborative and large manuscripts.

Decide with your PI who will be corresponding author. Usually you or the PI.

Circulate the manuscript draft to all possible authors. Thank them for their prior and ongoing support. Inform your co-authors where you would like to send the manuscript and why. Give them a reasonable deadline to provide feedback (minimum of a few weeks). If you use Microsoft Word, ask your co-authors to use track changes.

Collate comments from your co-authors. The Combine Documents function in Word can be very helpful. Consider reconciling all comments and tracked changes before circulating another manuscript draft so that co-authors can read a “clean” copy. Repeat this process until you and your PI (and co-authors) are satisfied that the manuscript is ready for submission.

Some prefer to avoid listing authors on manuscript drafts until the final version is generated because the relative contributions of authors can shift during manuscript preparation.

Submit your manuscript

Write a cover letter for your manuscript. Put it on institutional letterhead, if you are permitted by the journal’s submission system. This makes the cover letter, and by extension, the manuscript, more professional. Some journals have required language for cover letters regarding simultaneous submissions to other journals. It’s common for journals to require that cover letters include a rationale explaining the impact and findings of the manuscript. If you need to do this, include key references and a citation list at the end of the cover letter.

Most journals will require you to provide keywords, and/or to choose subject areas related to the manuscript. Be prepared to do so.

Conflicts of interest should be declared in the manuscript, even if the journal does not explicitly request this. Ask your co-authors about any such potential conflicts.

Gather names and official designations of any grants that supported the work described in your manuscript. Ask your co-authors and your PI. This is very important for funding agencies such as the NIH, which scrutinize the productivity of their funded investigators and take this into account when reviewing future grants.

It’s common for journals to allow you to suggest an editor to handle your manuscript. Editors with expertise in your area are more likely to be able to identify and recruit reviewers who are also well-versed in the subject matter of your manuscript. Discuss this with your PI and co-authors.

Likewise, journals often allow authors to suggest reviewers. Some meta-literature indicates that manuscripts with suggested reviewers have an overall higher acceptance rate. It also behooves you to have expert reviewers that can evaluate your manuscript fairly, but also provide feedback that can improve your paper if revisions are recommended. Avoid suggesting reviewers at your own institution or who have recently written papers or been awarded grants with you. Savvy editors look for these types of relationships between reviewers and authors, and will nix a suggested reviewer with any potential conflict of interest. Discuss suggested reviewers with your PI and co-authors.

On the flip side, many journals will allow you to list opposed reviewers. If you believe that someone specific will provide a negatively biased review for non-scientific reasons, that is grounds for opposing them as your manuscript’s reviewer. In small fields, it may not be possible to exclude reviewers and still undergo expert peer review. Definitely a must-discuss with your PI and co-authors.

Generate a final version of the manuscript. Most journals use online submission systems that mandate uploading individual files for the manuscript, cover letter, etc. You may have to use pdf converting software (i.e., Adobe Acrobat) to change Word documents to pdf’s, or to combine documents into a single pdf. Review the final version, including the resolution and appearance of figures. Make sure that no edges of text or graphics near page margins are cut off (Adobe Acrobat sometimes does this with Microsoft Word). Send the final version to your PI and co-authors. Revise any errors. Then submit! Good luck!

Edited by Bill Sullivan, PhD, Indiana University School of Medicine.

Michael Hsieh is the Stirewalt Scientific Director of the Biomedical Research Institute and an Associate Professor at the George Washington University, where he studies host-pathogen interactions in the urinary tract. Michael has published over 90 peer-reviewed scientific papers. His work has been featured on PBS and in the New York Times.

Your article is wonderful. just read it. you advise very correctly. I am an experienced writer. I write articles on various scientific topics. and even I took some information for myself, who I have not used before. Your article will help many novice writers. I’m sure of it. You very well described all the points of your article. I completely agree with them. most difficult to determine the target audience. Thanks to your article, everyone who needs some kind of help can get it by reading your article. Thanks you

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Written by Jessica Rech an undergraduate student at IUPUI and coauthored by Brandi Gilbert, director of LHSI. I am an undergraduate student…

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Writing a journal manuscript

Publishing your results is a vital step in the research lifecycle and in your career as a scientist. When you publish your results as a journal article, you make it possible for the scientific community to see it. Publishing your work allows you to get recognition for your results, and to exchange your ideas with the global scientific community. 

We have designed this tutorial to help you write the best article possible by providing you with points to consider, from your background reading and study design to manuscript structuring and figure preparation.

By the end of the tutorial you should know on how to:

• Prepare prior to starting your research
• Structure your manuscript and what to include in each section
• Get the most out of your tables and figures so that they clearly represent your most important results.

You will also have the opportunity to test your learning with quizzes as we go.

Writing a Journal Manuscript

Click here to begin the self-guided tutorial (registration required). 

For further support

We hope that with this tutorial you have a clearer idea of how the publication process works and feel confident in responding to editor and reviewers. Good luck with publishing your work!

If you feel that you would like some further support with writing your paper and understanding the peer review process, Springer Nature offer some services which may be of help.

• Nature Research Editing Service offers high quality  English language and scientific editing. During language editing , Editors will improve the English in your manuscript to ensure the meaning is clear and identify problems that require your review. With Scientific Editing experienced development editors will improve the scientific presentation of your research in your manuscript and cover letter, if supplied. They will also provide you with a report containing feedback on the most important issues identified during the edit, as well as journal recommendations.
• Our affiliates American Journal Experts also provide English language editing* as well as other author services that may support you in preparing your manuscript.
• We provide both online and face-to-face training for researchers on all aspects of the manuscript writing process.

* Please note, using an editing service is neither a requirement nor a guarantee of acceptance for publication. 

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• CAREER FEATURE
• 28 February 2018
• Correction 16 March 2018

How to write a first-class paper

• Virginia Gewin 0

Virginia Gewin is a freelance writer in Portland, Oregon.

You can also search for this author in PubMed   Google Scholar

Manuscripts may have a rigidly defined structure, but there’s still room to tell a compelling story — one that clearly communicates the science and is a pleasure to read. Scientist-authors and editors debate the importance and meaning of creativity and offer tips on how to write a top paper.

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Nature 555 , 129-130 (2018)

doi: https://doi.org/10.1038/d41586-018-02404-4

Interviews have been edited for clarity and length.

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Correction 16 March 2018 : This article should have made clear that Altmetric is part of Digital Science, a company owned by Holtzbrinck Publishing Group, which is also the majority shareholder in Nature’s publisher, Springer Nature. Nature Research Editing Services is also owned by Springer Nature.

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Structuring your manuscript

Once you have completed your experiments it is time write it up into a coherent and concise paper which tells the story of your research. Researchers are busy people and so it is imperative that research articles are quick and easy to read. For this reason papers generally follow a standard structure which allows readers to easily find the information they are looking for. In the next part of the course we will discuss the standard structure and what to include in each section.

Overview of IMRaD structure

IMRaD refers to the standard structure of the body of research manuscripts (after the Title and Abstract):

• I ntroduction
• M aterials and Methods
• D iscussion and Conclusions

Not all journals use these section titles in this order, but most published articles have a structure similar to IMRaD. This standard structure:

• Gives a logical flow to the content
• Makes journal manuscripts consistent and easy to read
• Provides a “map” so that readers can quickly find content of interest in any manuscript
• Reminds authors what content should be included in an article

Provides all content needed for the work to be replicated and reproduced Although the sections of the journal manuscript are published in the order: Title, Abstract, Introduction, Materials and Methods, Results, Discussion, and Conclusion, this is not the best order for writing the sections of a manuscript. One recommended strategy is to write your manuscript in the following order:

1. Materials and Methods

These can be written first, as you are doing your experiments and collecting the results.

3. Introduction

4. Discussion

5. Conclusion

Write these sections next, once you have had a chance to analyse your results, have a sense of their impact and have decided on the journal you think best suits the work

7. Abstract

Write your Title and Abstract last as these are based on all the other sections.

Following this order will help you write a logical and consistent manuscript.

Use the different sections of a manuscript to ‘tell a story’ about your research and its implications.

Back │ Next

A Guide on How to Write a Manuscript for a Research Paper

This article teaches how to write a manuscript for a research paper and recommended practices to produce a well-written manuscript.

For scientists, publishing a research paper is a huge accomplishment; they typically spend a large amount of time researching the appropriate subject, the right material, and, most importantly, the right place to publish their hard work. To be successful in publishing a research paper, it must be well-written and meet all of the high standards.

Although there is no quick and easy method to get published, there are certain manuscript writing strategies that can help earn the awareness and visibility you need to get it published.

In this Mind The Graph step-by-step tutorial, we give practical directions on how to write a manuscript for a research paper, to increase your research as well as your chances of publishing.

What is the manuscript of a research paper?

A manuscript is a written, typed, or word-processed document submitted to a publisher by the researcher. Researchers meticulously create manuscripts to communicate their unique ideas and fresh findings to both the scientific community and the general public. 

Overall, the manuscript must be outstanding and deeply represent your professional attitude towards work; it must be complete, rationally structured, and accurate. To convey the results to the scientific community while complying with ethical rules, scientific articles must use a specified language and structure.

Furthermore, the standards for title page information, abstract structure, reference style, font size, line spacing, margins, layout, and paragraph style must also be observed for effective publishing. This is a time-consuming and challenging technique, but it is worthwhile in the end.

How to structure a manuscript?

The first step in knowing how to write a manuscript for a research paper is understanding how the structure works. 

Title or heading

A poorly chosen title may deter a potential reader from reading deeper into your manuscript. When an audience comes across your manuscript, the first thing they notice is the title, keep in mind that the title you choose might impact the success of your work.

Abstracts are brief summaries of your paper. The fundamental concept of your research and the issues you intend to answer should be contained within the framework of the abstract. The abstract is a concise summary of the research that should be considered a condensed version of the entire article.

Introduction

The purpose of the research is disclosed in the body of the introduction. Background information is provided to explain why the study was conducted and the research’s development.

Methods and materials

The technical parts of the research have to be thoroughly detailed in this section. Transparency is required in this part of the research. Colleagues will learn about the methodology and materials you used to analyze your research, recreate it, and expand concepts further. 

This is the most important portion of the paper. You should provide your findings and data once the results have been thoroughly discussed. Use an unbiased point of view here; but leave the evaluation for your final piece, the conclusion.

Finally, explain why your findings are meaningful. This section allows you to evaluate your results and reflect on your process. Remember that conclusions are expressed in a succinct way using words rather than figures. The content presented in this section should solely be based on the research conducted.

The reference list contains information that readers may use to find the sources you mentioned in your research. Your reference page is at the end of your piece. Keep in mind that each publication has different submission criteria. For effective reference authentication, journal requirements should be followed.

Steps on how to write a manuscript for a research paper

It is not only about the format while writing a successful manuscript, but also about the correct strategy to stand out above other researchers trying to be published. Consider the following steps to a well-written manuscript:

1. Read the author’s guide

Many journals offer a Guide for Authors kind of document, which is normally printed yearly and is available online. In this Guide for Authors, you will discover thorough information on the journal’s interests and scope, as well as information regarding manuscript types and more in-depth instructions on how to do the right formatting to submit your research.

2. Pay special attention to the methods and materials section

The section on methods and materials is the most important part of the research. It should explain precisely what you observed in the research. This section should normally be less than 1,000 words long. The methods and materials used should be detailed enough that a colleague could reproduce the study.

3. Identify and describe your findings

The second most crucial aspect of your manuscript is the findings. After you’ve stated what you observed (methods and materials), you should go through what you discovered. Make a note to organize your findings such that they make sense without further explanation.

4. The research’s face and body

In this part you need to produce the face and body of your manuscript, so do it carefully and thoroughly. 

Ensure that the title page has all of the information required by the journal. The title page is the public face of your research and must be correctly structured to meet publication requirements. 

Write an introduction that explains why you carried out the research and why anybody should be interested in the results (ask yourself “so what?”). 

Concentrate on creating a clear and accurate reference page. As stated in step 1, you should read the author’s guide for the journal you intend to submit to thoroughly to ensure that your research reference page is correctly structured.

The abstract should be written just after the manuscript is finished. Follow the author’s guide and be sure to keep it under the word limit.

5. Rapid Rejection Criteria double-check

Now that you’ve completed the key aspects of your research, it’s time to double-check everything according to the Rapid Rejection Criteria. The “Rapid Rejection Criteria” are errors that lead to an instantaneous rejection. The criteria are:

• The answered question was not interesting enough
• The question has been satisfactorily answered before
• Wrong hypothesis
• The method cannot address the hypothesis
• Research is underpowered
• Contradictory manuscript
• The conclusion doesn’t support the data

Rewrite your manuscript now that you’ve finished it. Make yourself your fiercest critic. Consider reading the document loudly to yourself, keeping an ear out for any abrupt breaks in the logical flow or incorrect claims.

Your Creations, Ready within Minutes!

Aside from a step-by-step guide to writing a decent manuscript for your research, Mind The Graph includes a specialized tool for creating and providing templates for infographics that may maximize the potential and worth of your research. Check the website for more information. 

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About Jessica Abbadia

Jessica Abbadia is a lawyer that has been working in Digital Marketing since 2020, improving organic performance for apps and websites in various regions through ASO and SEO. Currently developing scientific and intellectual knowledge for the community's benefit. Jessica is an animal rights activist who enjoys reading and drinking strong coffee.

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How To Write A Research Paper

Step-By-Step Tutorial With Examples + FREE Template

By: Derek Jansen (MBA) | Expert Reviewer: Dr Eunice Rautenbach | March 2024

For many students, crafting a strong research paper from scratch can feel like a daunting task – and rightly so! In this post, we’ll unpack what a research paper is, what it needs to do , and how to write one – in three easy steps. 🙂 

Overview: Writing A Research Paper

What (exactly) is a research paper.

• How to write a research paper
• Stage 1 : Topic & literature search
• Stage 2 : Structure & outline
• Stage 3 : Iterative writing
• Key takeaways

Let’s start by asking the most important question, “ What is a research paper? ”.

Simply put, a research paper is a scholarly written work where the writer (that’s you!) answers a specific question (this is called a research question ) through evidence-based arguments . Evidence-based is the keyword here. In other words, a research paper is different from an essay or other writing assignments that draw from the writer’s personal opinions or experiences. With a research paper, it’s all about building your arguments based on evidence (we’ll talk more about that evidence a little later).

Now, it’s worth noting that there are many different types of research papers , including analytical papers (the type I just described), argumentative papers, and interpretative papers. Here, we’ll focus on analytical papers , as these are some of the most common – but if you’re keen to learn about other types of research papers, be sure to check out the rest of the blog .

With that basic foundation laid, let’s get down to business and look at how to write a research paper .

Overview: The 3-Stage Process

While there are, of course, many potential approaches you can take to write a research paper, there are typically three stages to the writing process. So, in this tutorial, we’ll present a straightforward three-step process that we use when working with students at Grad Coach.

These three steps are:

• Finding a research topic and reviewing the existing literature
• Developing a provisional structure and outline for your paper, and
• Writing up your initial draft and then refining it iteratively

Let’s dig into each of these.

Need a helping hand?

Step 1: Find a topic and review the literature

As we mentioned earlier, in a research paper, you, as the researcher, will try to answer a question . More specifically, that’s called a research question , and it sets the direction of your entire paper. What’s important to understand though is that you’ll need to answer that research question with the help of high-quality sources – for example, journal articles, government reports, case studies, and so on. We’ll circle back to this in a minute.

The first stage of the research process is deciding on what your research question will be and then reviewing the existing literature (in other words, past studies and papers) to see what they say about that specific research question. In some cases, your professor may provide you with a predetermined research question (or set of questions). However, in many cases, you’ll need to find your own research question within a certain topic area.

Finding a strong research question hinges on identifying a meaningful research gap – in other words, an area that’s lacking in existing research. There’s a lot to unpack here, so if you wanna learn more, check out the plain-language explainer video below.

Once you’ve figured out which question (or questions) you’ll attempt to answer in your research paper, you’ll need to do a deep dive into the existing literature – this is called a “ literature search ”. Again, there are many ways to go about this, but your most likely starting point will be Google Scholar .

If you’re new to Google Scholar, think of it as Google for the academic world. You can start by simply entering a few different keywords that are relevant to your research question and it will then present a host of articles for you to review. What you want to pay close attention to here is the number of citations for each paper – the more citations a paper has, the more credible it is (generally speaking – there are some exceptions, of course).

Ideally, what you’re looking for are well-cited papers that are highly relevant to your topic. That said, keep in mind that citations are a cumulative metric , so older papers will often have more citations than newer papers – just because they’ve been around for longer. So, don’t fixate on this metric in isolation – relevance and recency are also very important.

Beyond Google Scholar, you’ll also definitely want to check out academic databases and aggregators such as Science Direct, PubMed, JStor and so on. These will often overlap with the results that you find in Google Scholar, but they can also reveal some hidden gems – so, be sure to check them out.

Once you’ve worked your way through all the literature, you’ll want to catalogue all this information in some sort of spreadsheet so that you can easily recall who said what, when and within what context. If you’d like, we’ve got a free literature spreadsheet that helps you do exactly that.

Step 2: Develop a structure and outline

With your research question pinned down and your literature digested and catalogued, it’s time to move on to planning your actual research paper .

It might sound obvious, but it’s really important to have some sort of rough outline in place before you start writing your paper. So often, we see students eagerly rushing into the writing phase, only to land up with a disjointed research paper that rambles on in multiple

Now, the secret here is to not get caught up in the fine details . Realistically, all you need at this stage is a bullet-point list that describes (in broad strokes) what you’ll discuss and in what order. It’s also useful to remember that you’re not glued to this outline – in all likelihood, you’ll chop and change some sections once you start writing, and that’s perfectly okay. What’s important is that you have some sort of roadmap in place from the start.

At this stage you might be wondering, “ But how should I structure my research paper? ”. Well, there’s no one-size-fits-all solution here, but in general, a research paper will consist of a few relatively standardised components:

• Introduction
• Literature review
• Methodology

Let’s take a look at each of these.

First up is the introduction section . As the name suggests, the purpose of the introduction is to set the scene for your research paper. There are usually (at least) four ingredients that go into this section – these are the background to the topic, the research problem and resultant research question , and the justification or rationale. If you’re interested, the video below unpacks the introduction section in more detail. 

The next section of your research paper will typically be your literature review . Remember all that literature you worked through earlier? Well, this is where you’ll present your interpretation of all that content . You’ll do this by writing about recent trends, developments, and arguments within the literature – but more specifically, those that are relevant to your research question . The literature review can oftentimes seem a little daunting, even to seasoned researchers, so be sure to check out our extensive collection of literature review content here .

With the introduction and lit review out of the way, the next section of your paper is the research methodology . In a nutshell, the methodology section should describe to your reader what you did (beyond just reviewing the existing literature) to answer your research question. For example, what data did you collect, how did you collect that data, how did you analyse that data and so on? For each choice, you’ll also need to justify why you chose to do it that way, and what the strengths and weaknesses of your approach were.

Now, it’s worth mentioning that for some research papers, this aspect of the project may be a lot simpler . For example, you may only need to draw on secondary sources (in other words, existing data sets). In some cases, you may just be asked to draw your conclusions from the literature search itself (in other words, there may be no data analysis at all). But, if you are required to collect and analyse data, you’ll need to pay a lot of attention to the methodology section. The video below provides an example of what the methodology section might look like.

By this stage of your paper, you will have explained what your research question is, what the existing literature has to say about that question, and how you analysed additional data to try to answer your question. So, the natural next step is to present your analysis of that data . This section is usually called the “results” or “analysis” section and this is where you’ll showcase your findings.

Depending on your school’s requirements, you may need to present and interpret the data in one section – or you might split the presentation and the interpretation into two sections. In the latter case, your “results” section will just describe the data, and the “discussion” is where you’ll interpret that data and explicitly link your analysis back to your research question. If you’re not sure which approach to take, check in with your professor or take a look at past papers to see what the norms are for your programme.

Alright – once you’ve presented and discussed your results, it’s time to wrap it up . This usually takes the form of the “ conclusion ” section. In the conclusion, you’ll need to highlight the key takeaways from your study and close the loop by explicitly answering your research question. Again, the exact requirements here will vary depending on your programme (and you may not even need a conclusion section at all) – so be sure to check with your professor if you’re unsure.

Step 3: Write and refine

Finally, it’s time to get writing. All too often though, students hit a brick wall right about here… So, how do you avoid this happening to you?

Well, there’s a lot to be said when it comes to writing a research paper (or any sort of academic piece), but we’ll share three practical tips to help you get started.

First and foremost , it’s essential to approach your writing as an iterative process. In other words, you need to start with a really messy first draft and then polish it over multiple rounds of editing. Don’t waste your time trying to write a perfect research paper in one go. Instead, take the pressure off yourself by adopting an iterative approach.

Secondly , it’s important to always lean towards critical writing , rather than descriptive writing. What does this mean? Well, at the simplest level, descriptive writing focuses on the “ what ”, while critical writing digs into the “ so what ” – in other words, the implications . If you’re not familiar with these two types of writing, don’t worry! You can find a plain-language explanation here.

Last but not least, you’ll need to get your referencing right. Specifically, you’ll need to provide credible, correctly formatted citations for the statements you make. We see students making referencing mistakes all the time and it costs them dearly. The good news is that you can easily avoid this by using a simple reference manager . If you don’t have one, check out our video about Mendeley, an easy (and free) reference management tool that you can start using today.

Recap: Key Takeaways

We’ve covered a lot of ground here. To recap, the three steps to writing a high-quality research paper are:

• To choose a research question and review the literature
• To plan your paper structure and draft an outline
• To take an iterative approach to writing, focusing on critical writing and strong referencing

Remember, this is just a b ig-picture overview of the research paper development process and there’s a lot more nuance to unpack. So, be sure to grab a copy of our free research paper template to learn more about how to write a research paper.

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How to Write and Publish a Research Paper for a Peer-Reviewed Journal

• Open access
• Published: 30 April 2020
• Volume 36 , pages 909–913, ( 2021 )

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• Clara Busse   ORCID: orcid.org/0000-0002-0178-1000 1 &
• Ella August   ORCID: orcid.org/0000-0001-5151-1036 1 , 2  

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Communicating research findings is an essential step in the research process. Often, peer-reviewed journals are the forum for such communication, yet many researchers are never taught how to write a publishable scientific paper. In this article, we explain the basic structure of a scientific paper and describe the information that should be included in each section. We also identify common pitfalls for each section and recommend strategies to avoid them. Further, we give advice about target journal selection and authorship. In the online resource 1 , we provide an example of a high-quality scientific paper, with annotations identifying the elements we describe in this article.

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Introduction

Writing a scientific paper is an important component of the research process, yet researchers often receive little formal training in scientific writing. This is especially true in low-resource settings. In this article, we explain why choosing a target journal is important, give advice about authorship, provide a basic structure for writing each section of a scientific paper, and describe common pitfalls and recommendations for each section. In the online resource 1 , we also include an annotated journal article that identifies the key elements and writing approaches that we detail here. Before you begin your research, make sure you have ethical clearance from all relevant ethical review boards.

Select a Target Journal Early in the Writing Process

We recommend that you select a “target journal” early in the writing process; a “target journal” is the journal to which you plan to submit your paper. Each journal has a set of core readers and you should tailor your writing to this readership. For example, if you plan to submit a manuscript about vaping during pregnancy to a pregnancy-focused journal, you will need to explain what vaping is because readers of this journal may not have a background in this topic. However, if you were to submit that same article to a tobacco journal, you would not need to provide as much background information about vaping.

Information about a journal’s core readership can be found on its website, usually in a section called “About this journal” or something similar. For example, the Journal of Cancer Education presents such information on the “Aims and Scope” page of its website, which can be found here: https://www.springer.com/journal/13187/aims-and-scope .

Peer reviewer guidelines from your target journal are an additional resource that can help you tailor your writing to the journal and provide additional advice about crafting an effective article [ 1 ]. These are not always available, but it is worth a quick web search to find out.

Identify Author Roles Early in the Process

Early in the writing process, identify authors, determine the order of authors, and discuss the responsibilities of each author. Standard author responsibilities have been identified by The International Committee of Medical Journal Editors (ICMJE) [ 2 ]. To set clear expectations about each team member’s responsibilities and prevent errors in communication, we also suggest outlining more detailed roles, such as who will draft each section of the manuscript, write the abstract, submit the paper electronically, serve as corresponding author, and write the cover letter. It is best to formalize this agreement in writing after discussing it, circulating the document to the author team for approval. We suggest creating a title page on which all authors are listed in the agreed-upon order. It may be necessary to adjust authorship roles and order during the development of the paper. If a new author order is agreed upon, be sure to update the title page in the manuscript draft.

In the case where multiple papers will result from a single study, authors should discuss who will author each paper. Additionally, authors should agree on a deadline for each paper and the lead author should take responsibility for producing an initial draft by this deadline.

Structure of the Introduction Section

The introduction section should be approximately three to five paragraphs in length. Look at examples from your target journal to decide the appropriate length. This section should include the elements shown in Fig.  1 . Begin with a general context, narrowing to the specific focus of the paper. Include five main elements: why your research is important, what is already known about the topic, the “gap” or what is not yet known about the topic, why it is important to learn the new information that your research adds, and the specific research aim(s) that your paper addresses. Your research aim should address the gap you identified. Be sure to add enough background information to enable readers to understand your study. Table 1 provides common introduction section pitfalls and recommendations for addressing them.

The main elements of the introduction section of an original research article. Often, the elements overlap

Methods Section

The purpose of the methods section is twofold: to explain how the study was done in enough detail to enable its replication and to provide enough contextual detail to enable readers to understand and interpret the results. In general, the essential elements of a methods section are the following: a description of the setting and participants, the study design and timing, the recruitment and sampling, the data collection process, the dataset, the dependent and independent variables, the covariates, the analytic approach for each research objective, and the ethical approval. The hallmark of an exemplary methods section is the justification of why each method was used. Table 2 provides common methods section pitfalls and recommendations for addressing them.

Results Section

The focus of the results section should be associations, or lack thereof, rather than statistical tests. Two considerations should guide your writing here. First, the results should present answers to each part of the research aim. Second, return to the methods section to ensure that the analysis and variables for each result have been explained.

Begin the results section by describing the number of participants in the final sample and details such as the number who were approached to participate, the proportion who were eligible and who enrolled, and the number of participants who dropped out. The next part of the results should describe the participant characteristics. After that, you may organize your results by the aim or by putting the most exciting results first. Do not forget to report your non-significant associations. These are still findings.

Tables and figures capture the reader’s attention and efficiently communicate your main findings [ 3 ]. Each table and figure should have a clear message and should complement, rather than repeat, the text. Tables and figures should communicate all salient details necessary for a reader to understand the findings without consulting the text. Include information on comparisons and tests, as well as information about the sample and timing of the study in the title, legend, or in a footnote. Note that figures are often more visually interesting than tables, so if it is feasible to make a figure, make a figure. To avoid confusing the reader, either avoid abbreviations in tables and figures, or define them in a footnote. Note that there should not be citations in the results section and you should not interpret results here. Table 3 provides common results section pitfalls and recommendations for addressing them.

Discussion Section

Opposite the introduction section, the discussion should take the form of a right-side-up triangle beginning with interpretation of your results and moving to general implications (Fig.  2 ). This section typically begins with a restatement of the main findings, which can usually be accomplished with a few carefully-crafted sentences.

Major elements of the discussion section of an original research article. Often, the elements overlap

Next, interpret the meaning or explain the significance of your results, lifting the reader’s gaze from the study’s specific findings to more general applications. Then, compare these study findings with other research. Are these findings in agreement or disagreement with those from other studies? Does this study impart additional nuance to well-accepted theories? Situate your findings within the broader context of scientific literature, then explain the pathways or mechanisms that might give rise to, or explain, the results.

Journals vary in their approach to strengths and limitations sections: some are embedded paragraphs within the discussion section, while some mandate separate section headings. Keep in mind that every study has strengths and limitations. Candidly reporting yours helps readers to correctly interpret your research findings.

The next element of the discussion is a summary of the potential impacts and applications of the research. Should these results be used to optimally design an intervention? Does the work have implications for clinical protocols or public policy? These considerations will help the reader to further grasp the possible impacts of the presented work.

Finally, the discussion should conclude with specific suggestions for future work. Here, you have an opportunity to illuminate specific gaps in the literature that compel further study. Avoid the phrase “future research is necessary” because the recommendation is too general to be helpful to readers. Instead, provide substantive and specific recommendations for future studies. Table 4 provides common discussion section pitfalls and recommendations for addressing them.

Follow the Journal’s Author Guidelines

After you select a target journal, identify the journal’s author guidelines to guide the formatting of your manuscript and references. Author guidelines will often (but not always) include instructions for titles, cover letters, and other components of a manuscript submission. Read the guidelines carefully. If you do not follow the guidelines, your article will be sent back to you.

Finally, do not submit your paper to more than one journal at a time. Even if this is not explicitly stated in the author guidelines of your target journal, it is considered inappropriate and unprofessional.

Your title should invite readers to continue reading beyond the first page [ 4 , 5 ]. It should be informative and interesting. Consider describing the independent and dependent variables, the population and setting, the study design, the timing, and even the main result in your title. Because the focus of the paper can change as you write and revise, we recommend you wait until you have finished writing your paper before composing the title.

Be sure that the title is useful for potential readers searching for your topic. The keywords you select should complement those in your title to maximize the likelihood that a researcher will find your paper through a database search. Avoid using abbreviations in your title unless they are very well known, such as SNP, because it is more likely that someone will use a complete word rather than an abbreviation as a search term to help readers find your paper.

After you have written a complete draft, use the checklist (Fig. 3 ) below to guide your revisions and editing. Additional resources are available on writing the abstract and citing references [ 5 ]. When you feel that your work is ready, ask a trusted colleague or two to read the work and provide informal feedback. The box below provides a checklist that summarizes the key points offered in this article.

Checklist for manuscript quality

Data Availability

Michalek AM (2014) Down the rabbit hole…advice to reviewers. J Cancer Educ 29:4–5

Article   Google Scholar  

International Committee of Medical Journal Editors. Defining the role of authors and contributors: who is an author? http://www.icmje.org/recommendations/browse/roles-and-responsibilities/defining-the-role-of-authosrs-and-contributors.html . Accessed 15 January, 2020

Vetto JT (2014) Short and sweet: a short course on concise medical writing. J Cancer Educ 29(1):194–195

Brett M, Kording K (2017) Ten simple rules for structuring papers. PLoS ComputBiol. https://doi.org/10.1371/journal.pcbi.1005619

Lang TA (2017) Writing a better research article. J Public Health Emerg. https://doi.org/10.21037/jphe.2017.11.06

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Acknowledgments

Ella August is grateful to the Sustainable Sciences Institute for mentoring her in training researchers on writing and publishing their research.

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Busse, C., August, E. How to Write and Publish a Research Paper for a Peer-Reviewed Journal. J Canc Educ 36 , 909–913 (2021). https://doi.org/10.1007/s13187-020-01751-z

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How to Write a Research Paper 

• Smodin Editorial Team
• Updated: May 17, 2024

Most students hate writing research papers. The process can often feel long, tedious, and sometimes outright boring. Nevertheless, these assignments are vital to a student’s academic journey. Want to learn how to write a research paper that captures the depth of the subject and maintains the reader’s interest? If so, this guide is for you.

Today, we’ll show you how to assemble a well-organized research paper to help you make the grade. You can transform any topic into a compelling research paper with a thoughtful approach to your research and a persuasive argument.

In this guide, we’ll provide seven simple but practical tips to help demystify the process and guide you on your way. We’ll also explain how AI tools can expedite the research and writing process so you can focus on critical thinking.

By the end of this article, you’ll have a clear roadmap for tackling these essays. You will also learn how to tackle them quickly and efficiently. With time and dedication, you’ll soon master the art of research paper writing.

Ready to get started?

What Is a Research Paper?

A research paper is a comprehensive essay that gives a detailed analysis, interpretation, or argument based on your own independent research. In higher-level academic settings, it goes beyond a simple summarization and includes a deep inquiry into the topic or topics.

The term “research paper” is a broad term that can be applied to many different forms of academic writing. The goal is to combine your thoughts with the findings from peer-reviewed scholarly literature.

By the time your essay is done, you should have provided your reader with a new perspective or challenged existing findings. This demonstrates your mastery of the subject and contributes to ongoing scholarly debates.

7 Tips for Writing a Research Paper

Often, getting started is the most challenging part of a research paper. While the process can seem daunting, breaking it down into manageable steps can make it easier to manage. The following are seven tips for getting your ideas out of your head and onto the page.

1. Understand Your Assignment

It may sound simple, but the first step in writing a successful research paper is to read the assignment. Sit down, take a few moments of your time, and go through the instructions so you fully understand your assignment.

Misinterpreting the assignment can not only lead to a significant waste of time but also affect your grade. No matter how patient your teacher or professor may be, ignoring basic instructions is often inexcusable.

If you read the instructions and are still confused, ask for clarification before you start writing. If that’s impossible, you can use tools like Smodin’s AI chat to help. Smodin can help highlight critical requirements that you may overlook.

This initial investment ensures that all your future efforts will be focused and efficient. Remember, thinking is just as important as actually writing the essay, and it can also pave the wave for a smoother writing process.

2. Gather Research Materials

Now comes the fun part: doing the research. As you gather research materials, always use credible sources, such as academic journals or peer-reviewed papers. Only use search engines that filter for accredited sources and academic databases so you can ensure your information is reliable.

To optimize your time, you must learn to master the art of skimming. If a source seems relevant and valuable, save it and review it later. The last thing you want to do is waste time on material that won’t make it into the final paper.

To speed up the process even more, consider using Smodin’s AI summarizer . This tool can help summarize large texts, highlighting key information relevant to your topic. By systematically gathering and filing research materials early in the writing process, you build a strong foundation for your thesis.

3. Write Your Thesis

Creating a solid thesis statement is the most important thing you can do to bring structure and focus to your research paper. Your thesis should express the main point of your argument in one or two simple sentences. Remember, when you create your thesis, you’re setting the tone and direction for the entire paper.

Of course, you can’t just pull a winning thesis out of thin air. Start by brainstorming potential thesis ideas based on your preliminary research. And don’t overthink things; sometimes, the most straightforward ideas are often the best.

You want a thesis that is specific enough to be manageable within the scope of your paper but broad enough to allow for a unique discussion. Your thesis should challenge existing expectations and provide the reader with fresh insight into the topic. Use your thesis to hook the reader in the opening paragraph and keep them engaged until the very last word.

4. Write Your Outline

An outline is an often overlooked but essential tool for organizing your thoughts and structuring your paper. Many students skip the outline because it feels like doing double work, but a strong outline will save you work in the long run.

Here’s how to effectively structure your outline.

• Introduction: List your thesis statement and outline the main questions your essay will answer.
• Literature Review: Outline the key literature you plan to discuss and explain how it will relate to your thesis.
• Methodology: Explain the research methods you will use to gather and analyze the information.
• Discussion: Plan how you will interpret the results and their implications for your thesis.
• Conclusion: Summarize the content above to elucidate your thesis fully.

To further streamline this process, consider using Smodin’s Research Writer. This tool offers a feature that allows you to generate and tweak an outline to your liking based on the initial input you provide. You can adjust this outline to fit your research findings better and ensure that your paper remains well-organized and focused.

5. Write a Rough Draft

Once your outline is in place, you can begin the writing process. Remember, when you write a rough draft, it isn’t meant to be perfect. Instead, use it as a working document where you can experiment with and rearrange your arguments and evidence.

Don’t worry too much about grammar, style, or syntax as you write your rough draft. Focus on getting your ideas down on paper and flush out your thesis arguments. You can always refine and rearrange the content the next time around.

Follow the basic structure of your outline but with the freedom to explore different ways of expressing your thoughts. Smodin’s Essay Writer offers a powerful solution for those struggling with starting or structuring their drafts.

After you approve the outline, Smodin can generate an essay based on your initial inputs. This feature can help you quickly create a comprehensive draft, which you can then review and refine. You can even use the power of AI to create multiple rough drafts from which to choose.

6. Add or Subtract Supporting Evidence

Once you have a rough draft, but before you start the final revision, it’s time to do a little cleanup. In this phase, you need to review all your supporting evidence. You want to ensure that there is nothing redundant and that you haven’t overlooked any crucial details.

Many students struggle to make the required word count for an essay and resort to padding their writing with redundant statements. Instead of adding unnecessary content, focus on expanding your analysis to provide deeper insights.

A good essay, regardless of the topic or format, needs to be streamlined. It should convey clear, convincing, relevant information supporting your thesis. If you find some information doesn’t do that, consider tweaking your sources.

Include a variety of sources, including studies, data, and quotes from scholars or other experts. Remember, you’re not just strengthening your argument but demonstrating the depth of your research.

If you want comprehensive feedback on your essay without going to a writing center or pestering your professor, use Smodin. The AI Chat can look at your draft and offer suggestions for improvement.

7. Revise, Cite, and Submit

The final stages of crafting a research paper involve revision, citation, and final review. You must ensure your paper is polished, professionally presented, and plagiarism-free. Of course, integrating Smodin’s AI tools can significantly streamline this process and enhance the quality of your final submission.

Start by using Smodin’s Rewriter tool. This AI-powered feature can help rephrase and refine your draft to improve overall readability. If a specific section of your essay just “doesn’t sound right,” the AI can suggest alternative sentence structures and word choices.

Proper citation is a must for all academic papers. Thankfully, thanks to Smodin’s Research Paper app, this once tedious process is easier than ever. The AI ensures all sources are accurately cited according to the required style guide (APA, MLA, Chicago, etc.).

Plagiarism Checker:

All students need to realize that accidental plagiarism can happen. That’s why using a Plagiarism Checker to scan your essay before you submit it is always useful. Smodin’s Plagiarism Checker can highlight areas of concern so you can adjust accordingly.

Final Submission

After revising, rephrasing, and ensuring all citations are in order, use Smodin’s AI Content Detector to give your paper one last review. This tool can help you analyze your paper’s overall quality and readability so you can make any final tweaks or improvements.

Mastering Research Papers

Mastering the art of the research paper cannot be overstated, whether you’re in high school, college, or postgraduate studies. You can confidently prepare your research paper for submission by leveraging the AI tools listed above.

Research papers help refine your abilities to think critically and write persuasively. The skills you develop here will serve you well beyond the walls of the classroom. Communicating complex ideas clearly and effectively is one of the most powerful tools you can possess.

With the advancements of AI tools like Smodin , writing a research paper has become more accessible than ever before. These technologies streamline the process of organizing, writing, and revising your work. Write with confidence, knowing your best work is yet to come!